BACKGROUND Early diagnosis is key to prevent bowel damage in inflammatory bowel disease(IBD).Risk factor analyses linked with delayed diagnosis in European IBD patients are scarce and no data in German IBD patients ex...BACKGROUND Early diagnosis is key to prevent bowel damage in inflammatory bowel disease(IBD).Risk factor analyses linked with delayed diagnosis in European IBD patients are scarce and no data in German IBD patients exists.AIM To identify risk factors leading to prolonged diagnostic time in a German IBD cohort.METHODS Between 2012 and 2022,430 IBD patients from four Berlin hospitals were enrolled in a prospective study and asked to complete a 16-item questionnaire to determine features of the path leading to IBD diagnosis.Total diagnostic time was defined as the time from symptom onset to consulting a physician(patient waiting time)and from first consultation to IBD diagnosis(physician diagnostic time).Univariate and multivariate analyses were performed to identify risk factors for each time period.RESULTS The total diagnostic time was significantly longer in Crohn’s disease(CD)compared to ulcerative colitis(UC)patients(12.0 vs 4.0 mo;P<0.001),mainly due to increased physician diagnostic time(5.5 vs 1.0 mo;P<0.001).In a multivariate analysis,the predominant symptoms diarrhea(P=0.012)and skin lesions(P=0.028)as well as performed gastroscopy(P=0.042)were associated with longer physician diagnostic time in CD patients.In UC,fever was correlated(P=0.020)with shorter physician diagnostic time,while fatigue(P=0.011)and positive family history(P=0.046)were correlated with longer physician diagnostic time.CONCLUSION We demonstrated that CD patients compared to UC are at risk of long diagnostic delay.Future efforts should focus on shortening the diagnostic delay for a better outcome in these patients.展开更多
Turbine noise would be one of the dominant noise sources especially in future UHBR (Ultra High Bypass-Ratio) aeroengine, but its currently far from being studied enough. Acoustic mode is crucial for duct propagation b...Turbine noise would be one of the dominant noise sources especially in future UHBR (Ultra High Bypass-Ratio) aeroengine, but its currently far from being studied enough. Acoustic mode is crucial for duct propagation but little study about the relation between serration and mode. Thus, taking axial single-turbine test bench NPU-Turb as object, the effect of Stator with Serrated Trailing-edge (Bionic S) and Rotor with Serrated Leading-edge (Bionic R) on duct acoustic modes of turbine turbulence interac-tion noise were studied in detail using DDES/AA hybrid model validated by acoustic experiment of NPU-Turb. Serval conclusions can be made here. First, for broadband noise, the effect of serrations on duct modes (increased or reduced of PWL<sub>mn</sub>) with the increasing frequency is more prominent. Second, the changing trend of ?PWL<sub>mn</sub> is something like Chinese character “人” with circumferential mode m and alternating with radial mode. Such distribution is more obvious at higher frequency. More theoretical and mechanistic research work needs to be carried out in depth in the future. .展开更多
On the basis of the ideal gas model, the polarization of charges in the mantle was obtained, a physical and mathematical model was constructed, and estimated calculations of the dipole mode of the Earth’s magnetic fi...On the basis of the ideal gas model, the polarization of charges in the mantle was obtained, a physical and mathematical model was constructed, and estimated calculations of the dipole mode of the Earth’s magnetic field were performed, taking into account the speed of its angular rotation, the parameters of density and temperature, the chemical composition, the ionization potential, the dielectric constant and the percentage of the main chemical compounds of the mantle substance.展开更多
机场场面多点定位利用S模式信号到达时间差实现目标定位。针对S模式信号易受接收系统内部非线性影响和机场场面复杂电磁干扰的问题,研究S模式信号失真恢复方法。根据S模式信号频谱特征和接收基站弱非线性记忆系统特征简化Volterra级数,...机场场面多点定位利用S模式信号到达时间差实现目标定位。针对S模式信号易受接收系统内部非线性影响和机场场面复杂电磁干扰的问题,研究S模式信号失真恢复方法。根据S模式信号频谱特征和接收基站弱非线性记忆系统特征简化Volterra级数,降低计算量的同时满足Volterra级数关键核函数对S模式信号非线性失真表示能力,得到S模式信号失真恢复模型。仿真结果表明:3阶简化Volterra级数模型恢复15 dB和0 dB S模式信号前导脉冲的失真前波形,误差仅有2.23%和12.59%,且模型在典型运用环境下满足一定的适用性、抗干扰性和稳定性,为S模式信号到达时间戳的准确提取提供基础。展开更多
This paper introduces the system structure and work principle of the upgraded real time information system in Wangting Power Plant, and then expounds the realization way and function features of this system on B/S co...This paper introduces the system structure and work principle of the upgraded real time information system in Wangting Power Plant, and then expounds the realization way and function features of this system on B/S computing mode. The results of field application show the new system has good capability, reliability and expandability.展开更多
文摘BACKGROUND Early diagnosis is key to prevent bowel damage in inflammatory bowel disease(IBD).Risk factor analyses linked with delayed diagnosis in European IBD patients are scarce and no data in German IBD patients exists.AIM To identify risk factors leading to prolonged diagnostic time in a German IBD cohort.METHODS Between 2012 and 2022,430 IBD patients from four Berlin hospitals were enrolled in a prospective study and asked to complete a 16-item questionnaire to determine features of the path leading to IBD diagnosis.Total diagnostic time was defined as the time from symptom onset to consulting a physician(patient waiting time)and from first consultation to IBD diagnosis(physician diagnostic time).Univariate and multivariate analyses were performed to identify risk factors for each time period.RESULTS The total diagnostic time was significantly longer in Crohn’s disease(CD)compared to ulcerative colitis(UC)patients(12.0 vs 4.0 mo;P<0.001),mainly due to increased physician diagnostic time(5.5 vs 1.0 mo;P<0.001).In a multivariate analysis,the predominant symptoms diarrhea(P=0.012)and skin lesions(P=0.028)as well as performed gastroscopy(P=0.042)were associated with longer physician diagnostic time in CD patients.In UC,fever was correlated(P=0.020)with shorter physician diagnostic time,while fatigue(P=0.011)and positive family history(P=0.046)were correlated with longer physician diagnostic time.CONCLUSION We demonstrated that CD patients compared to UC are at risk of long diagnostic delay.Future efforts should focus on shortening the diagnostic delay for a better outcome in these patients.
文摘Turbine noise would be one of the dominant noise sources especially in future UHBR (Ultra High Bypass-Ratio) aeroengine, but its currently far from being studied enough. Acoustic mode is crucial for duct propagation but little study about the relation between serration and mode. Thus, taking axial single-turbine test bench NPU-Turb as object, the effect of Stator with Serrated Trailing-edge (Bionic S) and Rotor with Serrated Leading-edge (Bionic R) on duct acoustic modes of turbine turbulence interac-tion noise were studied in detail using DDES/AA hybrid model validated by acoustic experiment of NPU-Turb. Serval conclusions can be made here. First, for broadband noise, the effect of serrations on duct modes (increased or reduced of PWL<sub>mn</sub>) with the increasing frequency is more prominent. Second, the changing trend of ?PWL<sub>mn</sub> is something like Chinese character “人” with circumferential mode m and alternating with radial mode. Such distribution is more obvious at higher frequency. More theoretical and mechanistic research work needs to be carried out in depth in the future. .
文摘On the basis of the ideal gas model, the polarization of charges in the mantle was obtained, a physical and mathematical model was constructed, and estimated calculations of the dipole mode of the Earth’s magnetic field were performed, taking into account the speed of its angular rotation, the parameters of density and temperature, the chemical composition, the ionization potential, the dielectric constant and the percentage of the main chemical compounds of the mantle substance.
文摘机场场面多点定位利用S模式信号到达时间差实现目标定位。针对S模式信号易受接收系统内部非线性影响和机场场面复杂电磁干扰的问题,研究S模式信号失真恢复方法。根据S模式信号频谱特征和接收基站弱非线性记忆系统特征简化Volterra级数,降低计算量的同时满足Volterra级数关键核函数对S模式信号非线性失真表示能力,得到S模式信号失真恢复模型。仿真结果表明:3阶简化Volterra级数模型恢复15 dB和0 dB S模式信号前导脉冲的失真前波形,误差仅有2.23%和12.59%,且模型在典型运用环境下满足一定的适用性、抗干扰性和稳定性,为S模式信号到达时间戳的准确提取提供基础。
文摘This paper introduces the system structure and work principle of the upgraded real time information system in Wangting Power Plant, and then expounds the realization way and function features of this system on B/S computing mode. The results of field application show the new system has good capability, reliability and expandability.
