Assessment of the triglyceride glucose index in adult patients with chronic diarrhea and constipation

BACKGROUND Accumulating evidence suggests that the gut microbiome is involved in the pathogenesis of insulin resistance(IR).However,the link between two of the most prevalent bowel disorders,chronic diarrhea and constipation,and the triglyceride glucose(TyG)index,a marker of IR,has not yet been investigated.AIM To investigate the potential association between TyG and the incidence of chronic diarrhea and constipation.METHODS This cross-sectional study enrolled 2400 participants from the National Health and Nutrition Examination Survey database from 2009-2010.TyG was used as an exposure variable,with chronic diarrhea and constipation as determined by the Bristol Stool Form Scale used as the outcome variables.A demographic investigation based on TyG quartile subgroups was performed.The application of multivariate logistic regression models and weighted generalized additive models revealed potential correlations between TyG,chronic diarrhea,and constipation.Subgroup analyses were performed to examine the stability of any potential associations.RESULTS In the chosen sample,chronic diarrhea had a prevalence of 8.00%,while chronic constipation had a prevalence of 8.04%.In multiple logistic regression,a more prominent positive association was found between TyG and chronic diarrhea,particularly in model 1(OR=1.45;95%CI:1.17-1.79,P=0.0007)and model 2(OR=1.40;95%CI:1.12-1.76,P=0.0033).No definite association was observed between the TyG levels and chronic constipation.The weighted generalized additive model findings suggested a more substantial positive association with chronic diarrhea when TyG was less than 9.63(OR=1.89;95%CI:1.05-3.41,P=0.0344),and another positive association with chronic constipation when it was greater than 8.2(OR=1.74;95%CI:1.02-2.95,P=0.0415).The results of the subgroup analyses further strengthen the extrapolation of these results to a wide range of populations.CONCLUSION Higher TyG levels were positively associated with abnormal bowel health.

Correlation between the triglyceride glucose index and the degree of steatosis and liver fibrosis in nonalcoholic fatty liver disease

Objective:To investigate the relationship between triglyceride glucose index(TyG)and the degree of steatosis and liver fibrosis in patients with nonalcoholic fatty liver disease(NAFLD).Methods:Totally 2054 patients hospitalized in the second affiliated hospital of Xinjiang Medical University from September 2020 to September 2021 were retrospectively selected.According to abdominal ultrasound were divided into NAFLD group and non-NAFLD group.In accordance with the degree of steatosis,NAFLD patients were separated into mild group,moderate group and severe group.According to the liver stiffness,NAFLD patients were divided into liver fibrosis group and non-liver fibrosis group.We used the logistic regression to examine the correlation between TyG index and the the degree of steatosis and liver fibrosis.ROC curve was drawn to evaluate the diagnostic value of TyG index for NAFLD and liver fibrosis.Results:The prevalence of NAFLD increased with the increase of the interquartile of TyG index(Q_(1)44.1%,Q_(2)58.7%,Q_(3)71.9%,Q_(4)84.6%,P<0.001);The prevalence of liver fibrosis increased with the increase of the interquartile of TyG index(Q_(1)25.8%,Q_(2)30.2%,Q_(3)38.6%,Q_(4)44.3%,P<0.001).After adjusting for confounders,there was a correlation between TyG index and the degree of steatosis in NAFLD patients(the OR values of mild,moderate and severe groups were 1.383,2.450 and 3.070,P<0.001).TyG index was associated with liver fibrosis(OR=1.132,P<0.001).The ROC curve of TyG index predicted NAFLD was 0.701,with an optimal cutoff value of TyG is 8.57.However,the ROC curve of TyG index predicted liver fibrosis was 0.595.TyG index may not be a reliable predictor of liver fibrosis.Conclusion:TyG index was positively correlated with the degree of steatosis and liver fibrosis in NAFLD.

基于机-热-电多参量信号特征的GIS隔离开关状态评估方法

气体绝缘开关(gas insulated switchgear,GIS)设备中的隔离开关故障往往是机械、热、电气多物理量综合作用的结果,从微小缺陷发展至严重故障的过程中,会产生异常振动、温度、局部放电多种参量信号,同时测量并分析GIS隔离开关的多参量信息对于准确获取其运行状态具有重要意义。文中通过在实体220 kV GIS实验平台上模拟隔离开关最为常见的接触不良缺陷,研究不同接触状态时振动信号、温度变化和局部放电信号的演化规律,获得其与设备状态之间的对应关系,结合健康指数理论和改进层次分析法,提出基于多参量特征的GIS隔离开关综合评估方法。使用该方法开展现场测试,其检查结果与多参量综合评估方法的的分析结果相吻合。文中的研究为GIS隔离开关状态的带电检测提供了一种可行性较高的多参量融合分析新方法。

Determination of Fructose and Glucose Contents in Honey by Liquid Chromatography-refractive Index Detection Method and Direct Titration Method

In this study, fructose and glucose contents in honey were determined by liquid chromatography-refractive index detection method and alkaline copper tartrate solution-direct titration method. According to the results, there were great differences between determination results of reducing sugar contents by liquid chromatography-refractive index detection method and alkaline copper tartrate solution-direct titration method. Specifically, average determination results of reducing sugar contents by liquid chromatography-refractive index detection method were reduced by about 9.5% compared with alkaline copper tartrate solution-direct titra- tion method. Subsequently, determination results of reducing sugar contents by two methods were compared and analyzed. Liquid chromatography-refractive index detection method was used to determine fructose and glucose monomers in honey, but alkaline copper tartrate solution-direct titration method was used to determine reducing sugar composition in honey, which might lead to significantly different results. Due to small sample size and limited conditions, the determination results were not necessarily representative. Bee product acquisition and processing enterprises and relevant departments should pay much attention on these issues and fully consider the current situation of grass-roots units to develop scientific, rigorous, simple, universal, convenient, low-cost and practicable standards, thus ensuring the safety and reliability of food quality.

低GI枸杞杂粮代餐粉的体外消化特性

为探究低血糖生成指数(Glycemic index,GI)枸杞杂粮代餐粉的体外消化特性,本研究对各原料粉及代餐粉的基本组分、吸水率及吸水膨胀率、淀粉组分、淀粉水解率及估计血糖生成指数(Estimate Glycemic index,eGI)值进行测定与分析,并通过体外模拟胃肠消化方法对比分析了各原料粉及代餐粉中蛋白质水解率、总酚含量、黄酮含量及抗氧化活性的变化。结果表明,代餐粉中脂肪和粗纤维含量相较于各原料粉处于偏低水平。各原料粉及代餐粉的高温吸水率为常温吸水率的2倍左右,其中代餐粉吸水率最低(常温条件下吸水率为0.27%±0.05%,高温条件下吸水率为0.59%±0.05%)。代餐粉中快速消化淀粉含量(40.4%±0.003%)及eGI值(23.4)相较于各原料粉均达到最低,而慢消化淀粉和抗性淀粉含量均相对较高。体外模拟胃肠消化实验中,各原料粉及代餐粉蛋白质水解率均逐渐升高且水解主要以胃部为主,其中代餐粉蛋白水解率相对较高;总酚含量在胃肠消化期间均呈上升趋势且代餐粉在消化结束时含量达到最高(7.26 mg/g)。黄酮含量在模拟胃消化过程中明显增加,而在模拟肠消化中含量下降。DPPH自由基和ABTS+自由基清除率在模拟胃消化过程中随时间延长显著(P<0.05)上升,而在模拟肠消化过程中随时间延长呈先上升后降低趋势,但整体变化幅度较为平缓。综上所述,枸杞杂粮代餐粉适合作为低GI原料或产品且具有良好的抗氧化能力,对于杂粮制品的开发具有一定指导的意义。

Compressive near-field millimeter wave imaging algorithm based on Gini index and total variation mixed regularization

A compressive near-field millimeter wave(MMW)imaging algorithm is proposed.From the compressed sensing(CS)theory,the compressive near-field MMW imaging process can be considered to reconstruct an image from the under-sampled sparse data.The Gini index(GI)has been founded that it is the only sparsity measure that has all sparsity attributes that are called Robin Hood,Scaling,Rising Tide,Cloning,Bill Gates,and Babies.By combining the total variation(TV)operator,the GI-TV mixed regularization introduced compressive near-field MMW imaging model is proposed.In addition,the corresponding algorithm based on a primal-dual framework is also proposed.Experimental results demonstrate that the proposed GI-TV mixed regularization algorithm has superior convergence and stability performance compared with the widely used l1-TV mixed regularization algorithm.

基于RS与GIS技术的喀斯特煤矿区生态环境质量评价:以盘州市为例

针对喀斯特煤矿区特殊的地质环境特点,综合考虑影响生态环境质量的因素,选取与煤矿开采活动关联的指标因子,建立喀斯特煤矿区生态环境质量综合评价指标体系。通过对评价指标的分级处理,利用RS与GIS技术对指标因子进行单一评价分析,并在ArcGIS栅格数据空间叠加分析计算的支持下,采用综合指数法和层次分析法对盘州市生态环境质量进行综合评价,从而得到盘州市喀斯特煤矿区的生态环境质量等级。评价结果显示,盘州市生态环境质量大部分较好,优良等级占比达75.03%,但部分区域山高坡陡、植被覆盖度低及煤矿开采区相对应的生态环境情况较差;在生态环境保护及经济发展的规划中应以生态环境质量较差的区域为主,加强矿山土地复垦、植树造林等一系列生态恢复措施。在综合评价时引入生态环境质量网格化评价方法,通过一定范围内生态环境质量等级面积及权重的定量计算,为区域生态环境质量评价提供参考。

基于GIS的滇中地区人居环境适宜性评价

科学评估人居环境适宜性,有助于城市可持续发展,实现人类活动与自然环境和谐共处。研究基于地理信息系统(GIS)技术,以1 km×1 km栅格为基本研究单元,构建了滇中地区地形、水文、植被、气候单要素和综合人居环境适宜性评价模型与标准,从空间上定量评价了滇中地区的人居环境适宜性空间分布特征。研究表明:(1)从自然单要素的适宜性评价结果来看,气候、水文和地被的适宜性评价结果均以比较适宜为主;而地形是该区域人居环境适宜性的主要限制要素,且在空间上分区比较破碎,以一般适宜地区为主,主要分布在区域的西部和北部。(2)从人居环境适宜性综合评价结果来看,整体的人居环境状况较好,空间上呈片状分布的特征,临界适宜和一般适宜地区区域点总面积的80%以上;昆明市的不适宜地区面积占比最高,高度适宜地区面积较小但多数分布在楚雄州,曲靖市整体的人居环境状况最好。(3)结合人口数量和密度空间分布数据来看,人口分布与人居环境适宜性在空间分布上存在较高一致性,滇中地区近90%的人分布在临界适宜、一般适宜和比较适宜地区。

Triglyceride and Glucose Index (TyG) is a Reliable Biomarker to Predict Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is a common liver disease worldwide. There is no specific biomarker for the diagnosis of NAFLD. Trigly-ceride and glucose index (TyG) may predict the subsequent occurrence of NAFLD in later life. This cross sectional study was aimed to evaluate the effectiveness of triglyceride and glucose index (TyG) as a possible biomarker of NAFLD. The study was conducted at the Department of Laboratory Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2019 to February 2020. A total of 124 subjects were taken as study population following selection criteria. Among them 62 were diagnosed patients of NAFLD and 62 were healthy subjects as control group. Fasting plasma glucose was measured by glucose oxidase method and serum triglyceride was measured by enzymatic-colorimetric method, while TyG index was calculated accordingly. The mean age was 39.5 ± 11.27 years in NAFLD patients and 37.10 ± 12.28 years in control subjects with male female ratio 1:1.7 and 1:1.8 respectively. Major portion of NAFLD patients (62.9%) were overweight (BMI ≥ 25). The mean fasting plasma glucose level was 5.73 ± 1.47 mmol/L in NAFLD patients and 5.27 ± 0.69 mmol/L in control group (p < 0.027). The mean serum triglyceride level was 237.19 ± 96.47 mg/dl in NAFLD patients and 117.32 ± 53.07 mg/dl in control group (p < 0.001). The triglyceride and glucose index (TyG) was 9.36 ± 0.47 in NAFLD group and 8.53 ± 0.42 in control group. TyG index was significantly higher in NAFLD patients in comparison to control group (p < 0.001). In ROC analysis, cut off value of TyG index was 8.85 with sensitivity 93.5% and specificity 79%. As a fast and effective method, TyG index can be used as a diagnostic tool to predict NAFLD.

妊娠糖尿病患者早孕期间相关因素同围产结局的Logistic多因素回归分析

目的探究妊娠期糖尿病(GDM)患者早孕期身体质量指数(BMI)增幅和24 h内葡萄糖在目标范围内时间与围产结局之间的关系。方法回顾性分析2019年10月至2021年10月期间,郑州市金水区总医院收治的妊娠期糖尿病患者共计188例,全部研究对象均在妊娠期早期接受体BMI、血糖水平的定期监测;查阅患者病历资料,根据围产结局将全部研究对象划分为顺利妊娠组(n=123)以及不良结局组(n=65);收集患者一般资料信息,记录孕早期BMI增幅、空腹血糖(FBG)、24 h内葡萄糖在目标范围内时间、糖化血红蛋白(HbA1c)水平。首先采用单因素Logistic回归分析探究可能影响妊娠期糖尿病者围产结局的相关因素,随后将组间差异存在统计学意义的因素纳入Logistic多因素分析,并探究引发GDM患者不良围产结局的独立危险因素。结果单因素回归分析结果显示,不良结局组产妇存在妊娠合并高血压、GDM家族史的病例数占比高于顺利妊娠组,差异有统计学意义(P<0.05);另外,不良结局组产妇的母血乳酸、孕早期BMI指数增幅、FBG以及HbA1c水平显著高于顺利妊娠组产妇、葡萄糖在目标范围内时间低于顺利妊娠组产妇,差异有统计学意义(P<0.05);多因素回归分析结果显示,早孕期BMI增幅偏高、孕妇FBG、HbA1c水平偏高、葡萄糖在目标范围内时间偏低是造成GDM产妇不良围产结局的独立危险因素,差异有统计学意义(P<0.05)。结论GDM患者孕早期BMI增幅以及葡萄糖水平在目标范围时间内与围产结局存在显著的相关性,BMI增幅偏高、葡萄糖在目标范围内时间偏低、空腹血糖以及糖化血红蛋白偏高是造成GDM产妇不良围产结局的独立危险因素。

基于GIS与层次分析模型的生态旅游舒适度评价方法

为了提升区域范围内的生态旅游质量,针对生态旅游舒适度分析结果片面及冗余性的问题,提出基于地理信息系统(Geographic Information System,GIS)与层次分析(Analytic Hierarchy Process,AHP)模型的生态旅游舒适度评价方法。建立评价指标体系,通过两两对比判断矩阵及方根法确定生态旅游舒适度评价指标的权重值。结果显示:该方法所构建的评价指标体系信度较高,获取生态旅游舒适度评价结果准确,方法可行。

Triglyceride-glucose index predicts the prognosis of patients with acute myocardial infarction

Background Research has indicated that the triglyceride-glucose(Ty G)index is associated with the development and prognosis of cardiovascular diseases.However,there is still uncertainty regarding whether the Ty G index can predict adverse cardiovascular events in patients with acute myocardial infarction(AMI).The present study aimed to explore the prognostic value of the Ty G index in patients with AMI.Methods AMI patients who underwent emergency percutaneous coronary intervention(PCI)in Guangdong General Hospital from February 2021 to June 2022 were enrolled.The study population was grouped based on the median Ty G index.The end point of the study was major adverse cardiovascular events(MACEs),defined as all-cause mortality,cardiogenic shock,recurrent myocardial infarction,acute attack of heart failure,repeat revascularization induced by cardiac ischemia,and urgent visit due to aggravation of chest pain.The Ty G index was calculated as follows:LN[fasting triglycerides(mg/d L)×fasting blood glucose(mg/d L)x1/2].Results A total of 196 patients were included.In the multivariate logistic regression analysis,Ty G index[odds ratio(OR):0.99,95%confidence interval(CI):0.45-2.16,P=0.98]was not significantly correlated with the occurrence of MACEs in AMI patients during hospitalization.Afterwards a total of 178 patients were followed up for an average of 12.66±5.35 months.In the multivariate Cox proportional hazards model,Ty G index[hazard ratio(HR):1.91,95%CI:1.02-3.6,P<0.05]were independent predictor of adverse events during follow-up,and the area under the receiver operating characteristic(ROC)curve(AUC)was0.63(0.53-0.73,P<0.05).Conclusions Ty G index can independently predict the prognosis of AMI patients during the follow-up period.[S Chin J Cardiol 2024;25(1):11-20]

杂粮的有效利用——低GI(Glycaemic Index)食品的必要性(英文)

研究了在体重过多人群的食生活里导入杂粮的有效性以及杂粮食谱的营养价值。营养价值参考了日本厚生劳动省发表的"日本人食事摄取基准",这资料标示了目标热量、各种营养成分的目标摄取量以及许多项目的极限程度。因为极限程度与年龄、性别和生理状态有关,在此我们以普通生活的成人作为基准。杂粮中的营养成分,苋的热量358kcal、蛋白质12.7g、脂肪6.0g、糖质64.9g、食物纤维7.4g、Na 1.0mg、P540mg、Fe 9.4mg、Ca 160mg、K 600mg、Cu 0.92mg、Zn 5.8mg、Mn 6.14mg、维生素A 2.0ug以及微量的维生素C。经过研讨设计了营养平衡最佳的食谱为:糙米200g、苋50g、andeskinua50g、大豆110g、甘薯200g、绿黄色蔬菜(小青菜)300g、鸡蛋55g以及泥鳅100g。食用这个食谱可以摄取热量2007 kcal(是基准摄取量的100%),其他营养成分的摄取量与基准摄取量相比分别为:蛋白质173%、脂肪72%、碳水化物105%、K 332%、Ca262%、Mg 267%、P 250%、Fe 420%、Zn 183%、Cu 343%、VA 126%、VD 100%、VE 142%、VK 940%、VB1237%、VB2174%、烟碱酸201%、VB6218%、VB12375%、叶酸350%、泛酸160%、VC 176%、食物纤维185%、盐分5%以及Mn 273%。不足的盐分可以使用调味料来补充。氨基酸的摄取量推测是基准值的100%。蛋白质:脂肪:碳水化物的比例是19.0∶18.0∶63.0,与理想的平衡比接近。

基于GIS的田间精细化管理——以玉米种业田间种植为例

该文介绍基于GIS的田间精细化管理平台的设计与实现。以玉米田间种植指标的数字化为基础,采集田间种植过程关键指标数据,获取环境要素信息,对田间空间数据通过GIS进行转换、处理和分析,用以制定种植计划、规范田间管理、保证品种质量、建立种植绩效考核体系及提高工作效率。同时,当进入种子加工厂后,通过产品数字化技术及质量追溯平台,对产品生产加工、包装对应、仓库管理、订单、物流和销售等各个环节的信息进行有效采集、对应和管理,从而进行产品生命周期的全程监控,实现物流跟踪、质量控制及追溯等功能。

A Novel Hybrid Method for Measuring the Spatial Autocorrelation of Vehicular Crashes: Combining Moran’s Index and Getis-Ord G_i<sup style='margin-left:-7px;'>*</sup>Statistic

Spatial autocorrelation is a measure of the correlation of an observation with other observations through space. Most statistical analyses are based on the assumption that the values of observations are independent of one another. Spatial autocorrelation violates this assumption, because observations at near-by locations are related to each other, and hence, the consideration of spatial autocorrelations has been gaining attention in crash data modeling in recent years, and research have shown that ignoring this factor may lead to a biased estimation of the modeling parameters. This paper examines two spatial autocorrelation indices: Moran’s Index;and Getis-Ord Gi* statistic to measure the spatial autocorrelation of vehicle crashes occurred in Boone County roads in the state of Missouri, USA for the years 2013-2015. Since each index can identify different clustering patterns of crashes, therefore this paper introduces a new hybrid method to identify the crash clustering patterns by combining both Moran’s Index and Gi*?statistic. Results show that the new method can effectively improve the number, extent, and type of crash clustering along roadways.

Integrating Lithostratigraphic Units and GIS-Analysis Techniques to Modified Surface Water Quality Index

The purpose of this study is to investigate the effect of using Bicarbonate and Calcium parameters as alternatives to the lithostratigraphic units covered the catchment area, on water quality index (WQI) values that have been implemented with GIS technique at Wadi Al-Arab Dam. The analyzed results (by WQI method) have been used to depict water quality for the two approaches. Based on physico-chemical parameters, the calculated values for WQI over the 3-year for study period were 169, 168, and 157, respectively. While the WQI values were 184, 183 and 172, respectively, as a result of incorporated Bicarbonate and Calcium parameters in WQI calculations that significantly contributed to increasing the WQI. The elevated values may be attributed to the influence of carbonate stone dissolution and mechanical erosion under weathering conditions that are prevalent during winter season in the catchment area. As a consequence of lithostratigraphic unites product and GIS technique integration and normalization processes, most of water quality ranks are good and only autumn season has poor water quality in the 2012 and 2013, while in 2014 it has good water quality in the same season. The WQI values increase in general trend from winter to autumn seasons during the study period that may be referred to outflow by daily consumption, evaporation rising, and seepage water. The analysis shows that the modified water quality values of the Wadi Al-Arab Dam Reservoir (WADR) vary after using Bicarbonate and Calcium parameters by constant value. Generally, the results signify that the WADR is not polluted based on the physical and chemical characteristics of water.

Spatial/temporal indexing and information visualization genre for environmental digital libraries

Protecting and preserving our environmental systems require the ability to understand the spatio-temporal distri- bution of soils, parent material, topography, and land cover as well as the effects of human activities on ecosystems. Space-time modelling of ecosystems in an environmental digital library is essential for visualizing past, present, and future impacts of changes occurring within such landscapes (e.g., shift in land use practices). In this paper, we describe three novel features, spa- tio-temporal indexing, visualization, and geostatistical genre, for the environmental digital library, Environmental Visualization and Geographic Enterprise System (ENVISAGE), currently in progress at the University of Florida.

Spouses of patients with diabetes mellitus type 2 at increased risk of high blood glucose levels

Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to determine whether spouses of patients with diabetes mellitus have higher random blood glucose (RBG) levels as well as the benefit of RBG testing as a targetted screening tool. Methodology: The survey employed a cross-sectional comparative study of spouses’ of diabetics and non-diabetics attending the general out-patient department of the LagosStateUniversityTeaching Hospital (LASUTH), Ikeja. A modified WHO STEPS Surveillance Instrument and a one-touch Glucometer were used to collect data. Blood pressures and BMI were measured and correlated to blood glucose levels. Results: Prevalence of high RBG was found to be 7% among spouses of diabetics and 3.3% among spouses of non-diabetic patients. Mean RBG was 5.57 mmol/L and 7.7 mmol/L within the age group 40 - 49 years and 50 - 59 years respectively among spouses of diabetic patients compared to 5.4 mmol/L and 5.5 mmol/L within the same age group among the spouses non-diabetics. Spouses of patients with diabetes mellitus had higher systolic and diastolic blood pressures and BMI compared to spouses of non-diabetics. Conclusion: Being male, married to a diabetic patient, lower educational levels and higher body mass index are significantly associated with higher random blood glucose in the spouses of diabetic patients. Random blood glucose measurements are an effective screening tool and spouses of diabetic patients can benefit from targeted screening in controlled clinical settings.

Research of the Differential Uplifting in the Palongzangbu Region Based on the Synthesis of the Watershed Index and Seismic Data

Research on the differential uplifting in the Palongzangbu region is crucial to understanding the tectonic deformation mechanism and establishing the model of the faulted blocks in the region of the east structural knot.In this paper,based on the ASTER-30m DEM,we calculate the hypsometry index(HI)of 19 watersheds in the Palongzangbu region,and study the differential uplifting in this region combining with seismic data,the ground deposition and erosion process.The result shows that the spatial distribution of the HI value can reflect the differential uplifting in the study area.Differential uplifting exists within different zones,and there are 2 relative strong uplifting centers.One center is near the east structural knot,and the other lies between the Lhari fault and Nujiang fault at their converging segment.Also,the watershed evolution,seismic activity,and ground deposition and erosion process are closely related to each other,and they constitute a chain of evidence which reveals the whole process from the tectonic movement underground to the landform evolution on the surface.

Detection and Mapping of Water Quality Variation in the Godavari River Using Water Quality Index, Clustering and GIS Techniques

The objective of this research is to develop a tool for planning and managing the water quality of River Godavari. This is achieved by classifying the pollution levels of Godavari River into several categories using water quality index and a clustering approach that ensure simple but accurate information about the pollution levels and water characteristics at any point in Godavari River in Maharashtra. The derived water quality indices and clusters were then visualized by using a Geographical Information System to draw thematic maps of Godavari River, thus making GIS as a decision support system. The obtained maps may assist the decision makers in managing and controlling pollution in the Godavari River. This also provides an effective overview of those spots in the Godavari River where intensified monitoring activities are required. Consequently, the obtained results make a major contribution to the assessment of the State’s water quality monitoring network. Three significant groups (less polluted, moderately and highly polluted sites) were detected by Cluster Analysis method. The results of Discriminant Analysis revealed that five parameters?i.e.?pH, Dissolved Oxygen (DO), Faecal Coliform (FC), Total Coliform (TC) and Ammonical Nitrogen (NH3-N) were necessary for analysis in spatial variation. Using discriminant function developed in the analysis, 100% of the original sites were correctly classified.