El Ni?o–Southern Oscillation(ENSO) exhibits a distinctive phase-locking characteristic, first expressed during its onset in boreal spring, developing during summer and autumn, reaching its peak towards winter, and de...El Ni?o–Southern Oscillation(ENSO) exhibits a distinctive phase-locking characteristic, first expressed during its onset in boreal spring, developing during summer and autumn, reaching its peak towards winter, and decaying over the next spring. Several studies have demonstrated that this feature arises as a result of seasonal variation in the growth rate of ENSO as expressed by the sea surface temperature(SST). The bias towards simulating the phase locking of ENSO by many state-of-the-art climate models is also attributed to the unrealistic depiction of the growth rate. In this study, the seasonal variation of SST growth rate in the Ni?o-3.4 region(5°S–5°N, 120°–170°W) is estimated in detail based on the mixed layer heat budget equation and recharge oscillator model during 1981–2020. It is suggested that the consideration of a variable mixed layer depth is essential to its diagnostic process. The estimated growth rate has a remarkable seasonal cycle with minimum rates occurring in spring and maximum rates evident in autumn. More specifically, the growth rate derived from the meridional advection(surface heat flux) is positive(negative) throughout the year. Vertical diffusion generally makes a negative contribution to the evolution of growth rate and the magnitude of vertical entrainment represents the smallest contributor. Analysis indicates that the zonal advective feedback is regulated by the meridional immigration of the intertropical convergence zone, which approaches its southernmost extent in February and progresses to its northernmost location in September, and dominates the seasonal variation of the SST growth rate.展开更多
BACKGROUND In recent years,approximately half of the newly diagnosed cases and mortalities attributed to hepatocellular carcinoma(HCC)have been reported in China.Despite the high incidence of HCC,there remains a pauci...BACKGROUND In recent years,approximately half of the newly diagnosed cases and mortalities attributed to hepatocellular carcinoma(HCC)have been reported in China.Despite the high incidence of HCC,there remains a paucity of data regarding the natural growth pattern and the determination of optimal surveillance intervals specific to the Chinese population.AIM To quantify the natural tumor growth pattern of HCC in regional China.METHODS A retrospective analysis was performed on patients from a single institution in Southwest China who had undergone two or more serial dynamic computed tomography or magnetic resonance imaging scans between 2014 and 2020,without having received any anti-cancer therapy.Tumor growth was assessed using tumor volume doubling time(TVDT)and tumor growth rate(TGR),with volumes measured manually by experienced radiologists.Simple univariate linear regression and descriptive analysis were applied to explore associations between growth rates and clinical factors.RESULTS This study identifies the median TVDT for HCC as 163.4 d,interquartile range(IQR)72.1 to 302.3 d,with a daily TGR of 0.42%(IQR 0.206%-0.97%).HCC growth patterns reveal that about one-third of tumors grow indolently with TVDT exceeding 270 d,another one-third of tumors exhibit rapid growth with TVDT under 90 d,and the remaining tumors show intermediate growth rates,with TVDT ranging between 3 to 9 months.CONCLUSION The identified TGRs support biannual surveillance and follow-up for HCC patients in certain regions of China.Given the observed heterogeneity in HCC growth,further investigation is warranted.展开更多
From 20 January to 20 July 2023, a study was carried out on the Lobé Creek, a waterway subject to considerable natural and man-made pressures, with a negative impact on its biodiversity and habitats. The aim was ...From 20 January to 20 July 2023, a study was carried out on the Lobé Creek, a waterway subject to considerable natural and man-made pressures, with a negative impact on its biodiversity and habitats. The aim was to evaluate the growth rate of invasive aquatic macrophytes and their contribution to the use of organic fertilisers: a case of Eicchornia crassipes (Mart.) Solms, 1883 in the Lobé Creek (Littoral-Cameroon) with a view to its appropriate use in agronomy. The specific objective was to examine the impact of anthropogenic actions on Lobé Creek, characterise physico-chemical environment of the study area, and evaluate the growth rate of E. crassipes and its chemical composition with a view to producing an organic biofertiliser. The results show that E. crassipes represents a considerable threat to the populations of these localities. As for the physico-chemical parameters, the temperature values vary from 24 ± 1.41˚C to 26.5 ± 1.13˚C;pH from 6.3 ± 0.1 to 7.2 ± 0.07;conductivity and dissolved oxygen vary respectively from 40.7 ± 1.83 µS/cm to 19.6 ± 3.11 µS/cm and from 7.3 ± 0.14 mg/l to 5.8 ± 1.55 mg/l. Its average growth rate varies from 0.69 feet/day to 0.63 feet/day. With regard to the nitrogen, phosphorus and potassium content of water hyacinth plants, the results show that the average total nitrogen content ranges from 6.11 ± 1.59 g/kg to 5.2 ± 2.03 g/kg;total phosphorus, from 0.52 ± 0.54 g/kg to 0.88 ± 0.38 g/kg;and potassium, from 1.43 ± 0.45 g/kg to 2.61 ± 0.89 g/kg.展开更多
It is known that injection of carbon dioxide into the petroleum reservoir(CO_(2) flooding) is one of the effective methods for enhanced oil recovery. CO_(2) flooding may be complicated by formation of CO_(2) hydrate p...It is known that injection of carbon dioxide into the petroleum reservoir(CO_(2) flooding) is one of the effective methods for enhanced oil recovery. CO_(2) flooding may be complicated by formation of CO_(2) hydrate plugs. It makes topical investigation of CO_(2) hydrate formation in the system gaseous CO_(2)-oil-water. In this work, the growth rates of carbon dioxide hydrate films at the water-oil as well as the water-gas interface are studied in the pressure range of 2.30-3.04 MPa and at temperatures between -5.4 and 5.0℃. It is found that the growth rate for the water-oil interface is 3.5 times lower than that for the water-gas interface with carbon dioxide. It is hypothesised that the observed decrease in the growth rate is related to the mechanical resistance of the oil components adsorbed on the interface to the growth of the hydrate film. The growth rate of the film has been shown to depend on the experimental procedure,most likely due to the different initial concentrations of carbon dioxide in the aqueous solutions.展开更多
Inventory data were available from 96 plots of even-aged,monoculture,tall-open forests of Eucalyptus pilularis Smith,aged 2-63 years,growing in sub-tropical regions along the east coast of Australia.A model was develo...Inventory data were available from 96 plots of even-aged,monoculture,tall-open forests of Eucalyptus pilularis Smith,aged 2-63 years,growing in sub-tropical regions along the east coast of Australia.A model was developed relating the maximum possible stem basal area growth rate of individual trees to their stem basal area.For any tree size,this maximum increased as site productivity increased.However,the size at which this maximum occurred decreased as productivity increased.Much research has shown that,at any stand age,trees of a particular stem basal area are taller on more productive sites than on less productive ones.Taller trees incur greater respiratory costs to ensure maintenance of the photo synthetic capacity of their canopies;this reduces their growth rates.It was concluded that trees with larger basal areas will have the maximum possible growth rate on a less productive site,whilst trees with smaller basal areas will have the maximum possible on a more productive site.The model developed may constitute the first stage of a complete individual tree growth model system to predict wood yields from these forests.展开更多
Machine learning(ML)has powerful nonlinear processing and multivariate learning capabilities,so it has been widely utilised in the fatigue field.However,most ML methods are inexplicable black-box models that are diffi...Machine learning(ML)has powerful nonlinear processing and multivariate learning capabilities,so it has been widely utilised in the fatigue field.However,most ML methods are inexplicable black-box models that are difficult to apply in engineering practice.Symbolic regression(SR)is an interpretable machine learning method for determining the optimal fitting equation for datasets.In this study,domain knowledge-guided SR was used to determine a new fatigue crack growth(FCG)rate model.Three terms of the variable subtree ofΔK,R-ratio,andΔK_(th)were obtained by analysing eight traditional semi-empirical FCG rate models.Based on the FCG rate test data from other literature,the SR model was constructed using Al-7055-T7511.It was subsequently extended to other alloys(Ti-10V-2Fe-3Al,Ti-6Al-4V,Cr-Mo-V,LC9cs,Al-6013-T651,and Al-2324-T3)using multiple linear regression.Compared with the three semi-empirical FCG rate models,the SR model yielded higher prediction accuracy.This result demonstrates the potential of domain knowledge-guided SR for building the FCG rate model.展开更多
Objective:To evaluate the effects of an aqueous extract of Protaetia brevitarsis(AEPB)on the growth of zebrafish and preosteoblast MC3T3-E1 cells.Methods:The effects of AEPB on the linear growth and the expression of ...Objective:To evaluate the effects of an aqueous extract of Protaetia brevitarsis(AEPB)on the growth of zebrafish and preosteoblast MC3T3-E1 cells.Methods:The effects of AEPB on the linear growth and the expression of growth-related genes in zebrafish and MC3T3-E1 cells were assessed using various molecular techniques.Furthermore,the involvement of the mammalian target of rapamycin(mTOR)pathway in AEPB-induced growth was investigated by employing the mTOR inhibitor rapamycin.Results:AEPB administration led to a significant and dose-dependent increase in zebrafish larvae growth over time.Additionally,AEPB treatment upregulated the expression of growth hormone-1(GH-1),insulin-like growth factor-1(IGF-1),growth hormone receptor-1(GHR-1),and cholecystokinin-a(CCKA)in zebrafish.Similarly,AEPB stimulated the expression and release of IGF-1 and accelerated mTOR expression in MC3T3-E1 cells.In addition,rapamycin hindered AEPB-induced linear growth in zebrafish larvae and suppressed the expression of growth-promoting genes by inhibiting mTOR activation.Conclusions:AEPB shows growth-promoting effects by upregulating growth-related genes and activating the mTOR signaling pathway.Further investigations are warranted to elucidate its mechanisms of action and explore its potential application in the development of growth-enhancing supplements for various purposes.展开更多
Minerals and trace elements content and concentration in marine algae vary depending on species morphology and physiology;as well as growing environmental conditions. Despite this variability, accumulation of magnesiu...Minerals and trace elements content and concentration in marine algae vary depending on species morphology and physiology;as well as growing environmental conditions. Despite this variability, accumulation of magnesium, and especially iron, seems to be common in Chlorophyta;while Rhodophyta and Heterokontophyta show higher affinity to manganese. The red agarophyte Alsidium triquetrum was used to analyze the relationship between metal concentration, environmental conditions and growth rate. Specimens grown in situ showed a large variability of Fe, Mn, Mg, and Al, in thallus tissue concentrations. Further, a compelling relationship between the growth rate and the thallus concentration of Mg and Mn, Zn, and Al was detecte. Manganese, unlike the other trace elements analyzed showed a positive linear relationship between growth rate and tissue content during the period of greatest vegetative growth.展开更多
Purpose–The study aims to provide a basis for the effective use of safety-related information data and a quantitative assessment way for the occurrence probability of the safety risk such as the fatigue fracture of t...Purpose–The study aims to provide a basis for the effective use of safety-related information data and a quantitative assessment way for the occurrence probability of the safety risk such as the fatigue fracture of the key components.Design/methodology/approach–The fatigue crack growth rate is of dispersion,which is often used to accurately describe with probability density.In view of the external dispersion caused by the load,a simple and applicable probability expression of fatigue crack growth rate is adopted based on the fatigue growth theory.Considering the isolation among the pairs of crack length a and crack formation time t(a∼t data)obtained from same kind of structural parts,a statistical analysis approach of t distribution is proposed,which divides the crack length in several segments.Furthermore,according to the compatibility criterion of crack growth,that is,there is statistical development correspondence among a∼t data,the probability model of crack growth rate is established.Findings–The results show that the crack growth rate in the stable growth stage can be approximately expressed by the crack growth control curve da/dt=5 Q•a,and the probability density of the crack growth parameter Q represents the external dispersion;t follows two-parameter Weibull distribution in certain a values.Originality/value–The probability density f(Q)can be estimated by using the probability model of crack growth rate,and a calculation example shows that the estimation method is effective and practical.展开更多
Bridgman-type directional solidification experiments were conducted for Ti-46Al-8Nb (mole fraction, %) alloy. The effects of the growth rate and the diameter on the microstructure, phase transition and hardness of t...Bridgman-type directional solidification experiments were conducted for Ti-46Al-8Nb (mole fraction, %) alloy. The effects of the growth rate and the diameter on the microstructure, phase transition and hardness of the alloy were investigated. The results show that with the increase of the growth rate and the decrease of the diameter, the fullyβphase solidification changes to the peritectic solidification, and the final microstructure is composed of theα2/γlamellar structure and a multiphase microstructure (B2 phase,α2/γlamellar structure) respectively, which can be attributed to the solute enrichment resulting from the decreasing diffusion and convection ability. The occurrence of peritectic reaction at high growth rate promotes the solute segregation heavily and the coarse lamellar spacing in Al-and Nb-rich region, which greatly decreases the hardness values and leads to the discontinuity of the hardness curves with the increase of the growth rate. Comparatively, the Ti-46Al-8Nb alloy has lower hardness values than the other applied TiAl-based alloys in previous studies.展开更多
Objective] The aim of this study was to simultaneously isolate and identify the main pathogenic fungi of the root rot, black spot and round spot from the Panax notoginseng plants cultivated in Wenshan Eparchy of Yunna...Objective] The aim of this study was to simultaneously isolate and identify the main pathogenic fungi of the root rot, black spot and round spot from the Panax notoginseng plants cultivated in Wenshan Eparchy of Yunnan Province of China. [Method] The pathogenic fungi were isolated and purified by using potato dextrose agar (PDA) medium. The morphological identification was accomplished first according to the colony forms of the fungi when cultivated in vitro, then accord-ing to the symptom characteristics and colony forms of the re-isolated fungi in the reverse inoculation experiments. The molecular identification was performed accord-ing to the amplification and alignment of the internal transcribed space (ITS) se-quences of the fungi. The increases of the diameters and thickness of the colonies of the fungi cultivated in vitro were employed to indicate the growth rates of the fungi. [Results] The consistency of the colony forms and symptom characteristics and the 96%-99% similarities revealed in the ITS sequence alignments al proved that the main pathogenic fungi of the root rot, black spot and round spot of the P. notoginseng plants raised in Wenshan were Cylindrocarpon didymium, Alternaria panax and Mycocentrospora acerina, respectively. When cultivated in vitro in the same temperature, humidity and il umination, the increases of the colony diameters and thickness of C. didymium were the highest, fol owed by those of A. panax, then those of M. acerina. During different cultivation periods, the differences of the colony diameters and thickness of the three fungi al reached extremely significant level. However, at the same cultivation time, the differences of the diameters and thickness among the three fungi only reached significant level. [Conclusion] The main pathogenic fungi which result in the root rot, black spot and round spot of the P. notoginseng in Wenshan are C. didymium, A. panax and M. acerina, respec-tively. When these three diseases break out at the same time, the root rot wil spread fastest, fol owed orderly by the black spot and the round spot.展开更多
This paper examines the effect of supply-side structural reforms on China's potential economic growth rate in the coming decade according to the data the authors have gathered. Under the rapid growth scenario with th...This paper examines the effect of supply-side structural reforms on China's potential economic growth rate in the coming decade according to the data the authors have gathered. Under the rapid growth scenario with the implementation of supply-side structural reforms, China's potential economic growth rate will reach an average of 6.5% and 5.8% respectively in the 13th Five-year Plan (2016-2020) and 14th Five-year Plan (2021-2025) periods. These rates are 0.2 and 0.3 percentage points higher, respectively, than that under the baseline scenario with the inertia of historic trends. In implementing supply-side structural reforms, China must transform governmental functions, break monopolies, create a comprehensive competitive market environment, foster the creation of pro-innovation mechanisms, refocus on quality and efficiency, and raise capital utilization and labor productivity.展开更多
Different from other methodologies for the forecasting of China's economic growth rate, this paper forecast of future potential growth rates from the end of China's demographic dividends, and then identified it as a...Different from other methodologies for the forecasting of China's economic growth rate, this paper forecast of future potential growth rates from the end of China's demographic dividends, and then identified it as a growth target. Official promulgation of non-binding targets will guide social expectation, assist in government policy-making, boost confidence in consumers, and provide guidance for producers and investors. Based on our estimation results, we suggest that during the 13th Five-Year Plan period, a GDP growth target between 6. 5% and 7% would be appropriate.展开更多
Experimental study is performed on the probabilistic models for the long fatigue crack growth rates (da/dN) of LZ50 axle steel. An equation for crack growth rate was derived to consider the trend of stress intensity f...Experimental study is performed on the probabilistic models for the long fatigue crack growth rates (da/dN) of LZ50 axle steel. An equation for crack growth rate was derived to consider the trend of stress intensity factor range going down to the threshold and the average stress effect. The probabilistic models were presented on the equation. They consist of the probabilistic da/dN-ΔK relations, the confidence-based da/dN-ΔK relations, and the probabilistic- and confidence-based da/dN-ΔK relations. Efforts were made respectively to characterize the effects of probabilistic assessments due to the scattering regularity of test data, the number of sampling, and both of them. These relations can provide wide selections for practice. Analysis on the test data of LZ50 steel indicates that the present models are available and feasible.展开更多
The growth rates of bainite plates in an Fe-C-Mn-Si superbainitie steel were investigated by in situ observation. The lengthening rates of ferrite bainite during both cooling and isothermal holding processes were obse...The growth rates of bainite plates in an Fe-C-Mn-Si superbainitie steel were investigated by in situ observation. The lengthening rates of ferrite bainite during both cooling and isothermal holding processes were observed and the growth rates of bainite plates nucleating at grain boundaries, within grains and on preformed bainite were measured. It is indicated that the lengthening rates of bainite plates during the cooling and isothermal processes were different, and that the growth rates of bainite plates nucleating at different types of sites also demon- strated diversity. The bainite plates initiating at [vain boundaries during cooling grew the fastest, while the plates nucleating on preformed bainite did the slowest. However, the growth rate of the bainite plates nucleating at grain boundaries during isothermal transformation de- creased the most, whereas the bainite plates initiating within grains grew the fastest. In addition, the growth rate of ferrite bainite in the study supported the diffusion transformation mechanism of bainite from the viewooint of ~rowth rate.展开更多
The effects of precipitates on the fatigue crack growth rate of AA 7055 Al alloy subjected to different ageing treatments were investigated using transmission electron microscope and fatigue crack growth testing.The r...The effects of precipitates on the fatigue crack growth rate of AA 7055 Al alloy subjected to different ageing treatments were investigated using transmission electron microscope and fatigue crack growth testing.The results show that the T77 treated samples exhibit the lowest crack growth rate,while the crack growth rate of over-aged samples is the highest.In terms of the model based on the reversibility of dislocation motion within the plastic zone close to the crack tip,the improved crack growth resistance is attributed to many precipitates that are coherent with Al matrix in the under-aged and T77 treated samples.When the precipitate is coherent with the Al matrix,the larger the precipitate is,the slower the fatigue crack grows.The effects of grain boundary precipitates and precipitate free zone on the fatigue crack growth resistance are less significant than those of precipitates within grains of the alloy.展开更多
Experimental study is performed on the probabilistic models for the long fatigue crack growth rates (da/dN) of LZ50 axle steel. An equation for crack growth rate was derived to consider the trend of stress intensity...Experimental study is performed on the probabilistic models for the long fatigue crack growth rates (da/dN) of LZ50 axle steel. An equation for crack growth rate was derived to consider the trend of stress intensity factor range going down to the threshold and the average stress effect. The probabilistic models were presented on the equation. They consist of the probabilistic da/dN-△K relations, the confidence-based da/dN-△K relations, and the probabilistic- and confidence-based da/dN-△K relations. Efforts were made respectively to characterize the effects of probabilistic assessments due to the scattering regularity of test data, the number of sampling, and both of them. These relations can provide wide selections for practice. Analysis on the test data of LZ50 steel indicates that the present models are available and feasible.展开更多
Three types of fatigue tests for an annealed carbon steel containing carbon of 0.42%were carried out on smooth specimens and specimens with a small blind hole in order to investigate the fatigue crack growth law.A sim...Three types of fatigue tests for an annealed carbon steel containing carbon of 0.42%were carried out on smooth specimens and specimens with a small blind hole in order to investigate the fatigue crack growth law.A simple predicting method for crack growth rates has been proposed involving strengthσband the relation between cyclic stress and strain.The validity of proposed method has been confirmed by experiments on several carbon steels with different loadings.展开更多
An Al-5.3%Zn-5.3%Mg alloy was unidirectionally solidified to determine morphological transition and solute distribution by a modification of the Bridgman technique for crystal growth with growth rates ranging from 4-5...An Al-5.3%Zn-5.3%Mg alloy was unidirectionally solidified to determine morphological transition and solute distribution by a modification of the Bridgman technique for crystal growth with growth rates ranging from 4-500 μm/s and a temperature gradient of 25 K/cm. It was determined that growth rates from 6.5-9.5 μm/s generated a cell morphology, where the lower limit corresponds to the plane front to cellular transition and the upper limit indicates the cellular to columnar dendrite transition. The microstructures of the alloys solidified from 30 μm/s to growth rates less than 500 μm/s were mainly composed of columnar dendrites, while the microstructures solidified at growth rates greater than 500 μm/s were equiaxed. Regarding experimental results on solute distribution, a prediction of the model developed by Rappaz and Boettinger for dendrite solidification of multicomponent alloys was applied with excellent agreement. Results of solute distribution were employed to derive the precipitation fraction of τ-phase needed to increase the electrochemical properties of the alloy to be used as an Al-sacrificial anode.展开更多
The elementary task is to calculate the growth rates of disturbances when the e;method in transition prediction is performed. However, there is no unified knowledge to determine the growth rates of disturbances in thr...The elementary task is to calculate the growth rates of disturbances when the e;method in transition prediction is performed. However, there is no unified knowledge to determine the growth rates of disturbances in three-dimensional(3 D) flows. In this paper, we study the relation among the wave parameters of the disturbance in boundary layers in which the imaginary parts of wave parameters are far smaller than the real parts.The generalized growth rate(GGR) in the direction of group velocity is introduced, and the conservation relation of GGR is strictly deduced in theory. This conservation relation manifests that the GGR only depends on the real parts of wave parameters instead of the imaginary parts. Numerical validations for GGR conservation are also provided in the cases of first/second modes and crossflow modes. The application of GGR to the eN method in 3 D flows is discussed, and the puzzle of determining growth rates in 3 D flows is clarified. A convenient method is also proposed to calculate growth rates of disturbances in 3 D flows. Good agreement between this convenient method and existing methods is found except the condition that the angle between the group velocity direction and the x-direction is close to 90?which can be easily avoided in practical application.展开更多
基金supported by the National Natural Science Foundation of China (Grant No. 42192564)Guangdong Major Project of Basic and Applied Basic Research (Grant No. 2020B0301030004)the Ministry of Science and Technology of the People's Republic of China (Grant No.2020YFA0608802)。
文摘El Ni?o–Southern Oscillation(ENSO) exhibits a distinctive phase-locking characteristic, first expressed during its onset in boreal spring, developing during summer and autumn, reaching its peak towards winter, and decaying over the next spring. Several studies have demonstrated that this feature arises as a result of seasonal variation in the growth rate of ENSO as expressed by the sea surface temperature(SST). The bias towards simulating the phase locking of ENSO by many state-of-the-art climate models is also attributed to the unrealistic depiction of the growth rate. In this study, the seasonal variation of SST growth rate in the Ni?o-3.4 region(5°S–5°N, 120°–170°W) is estimated in detail based on the mixed layer heat budget equation and recharge oscillator model during 1981–2020. It is suggested that the consideration of a variable mixed layer depth is essential to its diagnostic process. The estimated growth rate has a remarkable seasonal cycle with minimum rates occurring in spring and maximum rates evident in autumn. More specifically, the growth rate derived from the meridional advection(surface heat flux) is positive(negative) throughout the year. Vertical diffusion generally makes a negative contribution to the evolution of growth rate and the magnitude of vertical entrainment represents the smallest contributor. Analysis indicates that the zonal advective feedback is regulated by the meridional immigration of the intertropical convergence zone, which approaches its southernmost extent in February and progresses to its northernmost location in September, and dominates the seasonal variation of the SST growth rate.
基金Supported by Cultivate Project for the National Natural Science Foundation of China,No.gyfynsfc[2020]-27and National Natural Science Foundation of China,No.81960328.
文摘BACKGROUND In recent years,approximately half of the newly diagnosed cases and mortalities attributed to hepatocellular carcinoma(HCC)have been reported in China.Despite the high incidence of HCC,there remains a paucity of data regarding the natural growth pattern and the determination of optimal surveillance intervals specific to the Chinese population.AIM To quantify the natural tumor growth pattern of HCC in regional China.METHODS A retrospective analysis was performed on patients from a single institution in Southwest China who had undergone two or more serial dynamic computed tomography or magnetic resonance imaging scans between 2014 and 2020,without having received any anti-cancer therapy.Tumor growth was assessed using tumor volume doubling time(TVDT)and tumor growth rate(TGR),with volumes measured manually by experienced radiologists.Simple univariate linear regression and descriptive analysis were applied to explore associations between growth rates and clinical factors.RESULTS This study identifies the median TVDT for HCC as 163.4 d,interquartile range(IQR)72.1 to 302.3 d,with a daily TGR of 0.42%(IQR 0.206%-0.97%).HCC growth patterns reveal that about one-third of tumors grow indolently with TVDT exceeding 270 d,another one-third of tumors exhibit rapid growth with TVDT under 90 d,and the remaining tumors show intermediate growth rates,with TVDT ranging between 3 to 9 months.CONCLUSION The identified TGRs support biannual surveillance and follow-up for HCC patients in certain regions of China.Given the observed heterogeneity in HCC growth,further investigation is warranted.
文摘From 20 January to 20 July 2023, a study was carried out on the Lobé Creek, a waterway subject to considerable natural and man-made pressures, with a negative impact on its biodiversity and habitats. The aim was to evaluate the growth rate of invasive aquatic macrophytes and their contribution to the use of organic fertilisers: a case of Eicchornia crassipes (Mart.) Solms, 1883 in the Lobé Creek (Littoral-Cameroon) with a view to its appropriate use in agronomy. The specific objective was to examine the impact of anthropogenic actions on Lobé Creek, characterise physico-chemical environment of the study area, and evaluate the growth rate of E. crassipes and its chemical composition with a view to producing an organic biofertiliser. The results show that E. crassipes represents a considerable threat to the populations of these localities. As for the physico-chemical parameters, the temperature values vary from 24 ± 1.41˚C to 26.5 ± 1.13˚C;pH from 6.3 ± 0.1 to 7.2 ± 0.07;conductivity and dissolved oxygen vary respectively from 40.7 ± 1.83 µS/cm to 19.6 ± 3.11 µS/cm and from 7.3 ± 0.14 mg/l to 5.8 ± 1.55 mg/l. Its average growth rate varies from 0.69 feet/day to 0.63 feet/day. With regard to the nitrogen, phosphorus and potassium content of water hyacinth plants, the results show that the average total nitrogen content ranges from 6.11 ± 1.59 g/kg to 5.2 ± 2.03 g/kg;total phosphorus, from 0.52 ± 0.54 g/kg to 0.88 ± 0.38 g/kg;and potassium, from 1.43 ± 0.45 g/kg to 2.61 ± 0.89 g/kg.
基金supported by a grant from the Ministry of Science and Higher Education of Russia, Agreement No. 075-152020-806 (Contract No. 13.1902.21.0014)。
文摘It is known that injection of carbon dioxide into the petroleum reservoir(CO_(2) flooding) is one of the effective methods for enhanced oil recovery. CO_(2) flooding may be complicated by formation of CO_(2) hydrate plugs. It makes topical investigation of CO_(2) hydrate formation in the system gaseous CO_(2)-oil-water. In this work, the growth rates of carbon dioxide hydrate films at the water-oil as well as the water-gas interface are studied in the pressure range of 2.30-3.04 MPa and at temperatures between -5.4 and 5.0℃. It is found that the growth rate for the water-oil interface is 3.5 times lower than that for the water-gas interface with carbon dioxide. It is hypothesised that the observed decrease in the growth rate is related to the mechanical resistance of the oil components adsorbed on the interface to the growth of the hydrate film. The growth rate of the film has been shown to depend on the experimental procedure,most likely due to the different initial concentrations of carbon dioxide in the aqueous solutions.
文摘Inventory data were available from 96 plots of even-aged,monoculture,tall-open forests of Eucalyptus pilularis Smith,aged 2-63 years,growing in sub-tropical regions along the east coast of Australia.A model was developed relating the maximum possible stem basal area growth rate of individual trees to their stem basal area.For any tree size,this maximum increased as site productivity increased.However,the size at which this maximum occurred decreased as productivity increased.Much research has shown that,at any stand age,trees of a particular stem basal area are taller on more productive sites than on less productive ones.Taller trees incur greater respiratory costs to ensure maintenance of the photo synthetic capacity of their canopies;this reduces their growth rates.It was concluded that trees with larger basal areas will have the maximum possible growth rate on a less productive site,whilst trees with smaller basal areas will have the maximum possible on a more productive site.The model developed may constitute the first stage of a complete individual tree growth model system to predict wood yields from these forests.
基金Supported by Sichuan Provincial Science and Technology Program(Grant No.2022YFH0075)Opening Project of State Key Laboratory of Performance Monitoring and Protecting of Rail Transit Infrastructure(Grant No.HJGZ2021113)Independent Research Project of State Key Laboratory of Traction Power(Grant No.2022TPL_T03).
文摘Machine learning(ML)has powerful nonlinear processing and multivariate learning capabilities,so it has been widely utilised in the fatigue field.However,most ML methods are inexplicable black-box models that are difficult to apply in engineering practice.Symbolic regression(SR)is an interpretable machine learning method for determining the optimal fitting equation for datasets.In this study,domain knowledge-guided SR was used to determine a new fatigue crack growth(FCG)rate model.Three terms of the variable subtree ofΔK,R-ratio,andΔK_(th)were obtained by analysing eight traditional semi-empirical FCG rate models.Based on the FCG rate test data from other literature,the SR model was constructed using Al-7055-T7511.It was subsequently extended to other alloys(Ti-10V-2Fe-3Al,Ti-6Al-4V,Cr-Mo-V,LC9cs,Al-6013-T651,and Al-2324-T3)using multiple linear regression.Compared with the three semi-empirical FCG rate models,the SR model yielded higher prediction accuracy.This result demonstrates the potential of domain knowledge-guided SR for building the FCG rate model.
基金supported by the 2023 scientific promotion program funded by Jeju National University.
文摘Objective:To evaluate the effects of an aqueous extract of Protaetia brevitarsis(AEPB)on the growth of zebrafish and preosteoblast MC3T3-E1 cells.Methods:The effects of AEPB on the linear growth and the expression of growth-related genes in zebrafish and MC3T3-E1 cells were assessed using various molecular techniques.Furthermore,the involvement of the mammalian target of rapamycin(mTOR)pathway in AEPB-induced growth was investigated by employing the mTOR inhibitor rapamycin.Results:AEPB administration led to a significant and dose-dependent increase in zebrafish larvae growth over time.Additionally,AEPB treatment upregulated the expression of growth hormone-1(GH-1),insulin-like growth factor-1(IGF-1),growth hormone receptor-1(GHR-1),and cholecystokinin-a(CCKA)in zebrafish.Similarly,AEPB stimulated the expression and release of IGF-1 and accelerated mTOR expression in MC3T3-E1 cells.In addition,rapamycin hindered AEPB-induced linear growth in zebrafish larvae and suppressed the expression of growth-promoting genes by inhibiting mTOR activation.Conclusions:AEPB shows growth-promoting effects by upregulating growth-related genes and activating the mTOR signaling pathway.Further investigations are warranted to elucidate its mechanisms of action and explore its potential application in the development of growth-enhancing supplements for various purposes.
文摘Minerals and trace elements content and concentration in marine algae vary depending on species morphology and physiology;as well as growing environmental conditions. Despite this variability, accumulation of magnesium, and especially iron, seems to be common in Chlorophyta;while Rhodophyta and Heterokontophyta show higher affinity to manganese. The red agarophyte Alsidium triquetrum was used to analyze the relationship between metal concentration, environmental conditions and growth rate. Specimens grown in situ showed a large variability of Fe, Mn, Mg, and Al, in thallus tissue concentrations. Further, a compelling relationship between the growth rate and the thallus concentration of Mg and Mn, Zn, and Al was detecte. Manganese, unlike the other trace elements analyzed showed a positive linear relationship between growth rate and tissue content during the period of greatest vegetative growth.
基金This research was supported by the China National Railway Group Co.,Ltd.Research and Development Project(N2022T008).
文摘Purpose–The study aims to provide a basis for the effective use of safety-related information data and a quantitative assessment way for the occurrence probability of the safety risk such as the fatigue fracture of the key components.Design/methodology/approach–The fatigue crack growth rate is of dispersion,which is often used to accurately describe with probability density.In view of the external dispersion caused by the load,a simple and applicable probability expression of fatigue crack growth rate is adopted based on the fatigue growth theory.Considering the isolation among the pairs of crack length a and crack formation time t(a∼t data)obtained from same kind of structural parts,a statistical analysis approach of t distribution is proposed,which divides the crack length in several segments.Furthermore,according to the compatibility criterion of crack growth,that is,there is statistical development correspondence among a∼t data,the probability model of crack growth rate is established.Findings–The results show that the crack growth rate in the stable growth stage can be approximately expressed by the crack growth control curve da/dt=5 Q•a,and the probability density of the crack growth parameter Q represents the external dispersion;t follows two-parameter Weibull distribution in certain a values.Originality/value–The probability density f(Q)can be estimated by using the probability model of crack growth rate,and a calculation example shows that the estimation method is effective and practical.
基金Projects(51071062,51274077,51271068)supported by the National Natural Science Foundation of ChinaProject(2011-P03)supported by Open Fund of State Key Laboratory of Mold and Die Technology of Huazhong University of Science and Technology+1 种基金Project(HIT.NSRIF.2013002)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(2011CB605504)supported by the National Basic Research Program of China
文摘Bridgman-type directional solidification experiments were conducted for Ti-46Al-8Nb (mole fraction, %) alloy. The effects of the growth rate and the diameter on the microstructure, phase transition and hardness of the alloy were investigated. The results show that with the increase of the growth rate and the decrease of the diameter, the fullyβphase solidification changes to the peritectic solidification, and the final microstructure is composed of theα2/γlamellar structure and a multiphase microstructure (B2 phase,α2/γlamellar structure) respectively, which can be attributed to the solute enrichment resulting from the decreasing diffusion and convection ability. The occurrence of peritectic reaction at high growth rate promotes the solute segregation heavily and the coarse lamellar spacing in Al-and Nb-rich region, which greatly decreases the hardness values and leads to the discontinuity of the hardness curves with the increase of the growth rate. Comparatively, the Ti-46Al-8Nb alloy has lower hardness values than the other applied TiAl-based alloys in previous studies.
基金Supported by the National Natural Science Foundation of China(31060045,31260091,31460065)~~
文摘Objective] The aim of this study was to simultaneously isolate and identify the main pathogenic fungi of the root rot, black spot and round spot from the Panax notoginseng plants cultivated in Wenshan Eparchy of Yunnan Province of China. [Method] The pathogenic fungi were isolated and purified by using potato dextrose agar (PDA) medium. The morphological identification was accomplished first according to the colony forms of the fungi when cultivated in vitro, then accord-ing to the symptom characteristics and colony forms of the re-isolated fungi in the reverse inoculation experiments. The molecular identification was performed accord-ing to the amplification and alignment of the internal transcribed space (ITS) se-quences of the fungi. The increases of the diameters and thickness of the colonies of the fungi cultivated in vitro were employed to indicate the growth rates of the fungi. [Results] The consistency of the colony forms and symptom characteristics and the 96%-99% similarities revealed in the ITS sequence alignments al proved that the main pathogenic fungi of the root rot, black spot and round spot of the P. notoginseng plants raised in Wenshan were Cylindrocarpon didymium, Alternaria panax and Mycocentrospora acerina, respectively. When cultivated in vitro in the same temperature, humidity and il umination, the increases of the colony diameters and thickness of C. didymium were the highest, fol owed by those of A. panax, then those of M. acerina. During different cultivation periods, the differences of the colony diameters and thickness of the three fungi al reached extremely significant level. However, at the same cultivation time, the differences of the diameters and thickness among the three fungi only reached significant level. [Conclusion] The main pathogenic fungi which result in the root rot, black spot and round spot of the P. notoginseng in Wenshan are C. didymium, A. panax and M. acerina, respec-tively. When these three diseases break out at the same time, the root rot wil spread fastest, fol owed orderly by the black spot and the round spot.
文摘This paper examines the effect of supply-side structural reforms on China's potential economic growth rate in the coming decade according to the data the authors have gathered. Under the rapid growth scenario with the implementation of supply-side structural reforms, China's potential economic growth rate will reach an average of 6.5% and 5.8% respectively in the 13th Five-year Plan (2016-2020) and 14th Five-year Plan (2021-2025) periods. These rates are 0.2 and 0.3 percentage points higher, respectively, than that under the baseline scenario with the inertia of historic trends. In implementing supply-side structural reforms, China must transform governmental functions, break monopolies, create a comprehensive competitive market environment, foster the creation of pro-innovation mechanisms, refocus on quality and efficiency, and raise capital utilization and labor productivity.
文摘Different from other methodologies for the forecasting of China's economic growth rate, this paper forecast of future potential growth rates from the end of China's demographic dividends, and then identified it as a growth target. Official promulgation of non-binding targets will guide social expectation, assist in government policy-making, boost confidence in consumers, and provide guidance for producers and investors. Based on our estimation results, we suggest that during the 13th Five-Year Plan period, a GDP growth target between 6. 5% and 7% would be appropriate.
基金Project supported by the National Natural Science Foundation of China (Nos.50375130and50323003), the Special Foundation of National Excellent Ph.D.Thesis (No.200234) and thePlanned Itemforthe Outstanding Young Teachers ofMinistry ofEducationofChina (No.2101)
文摘Experimental study is performed on the probabilistic models for the long fatigue crack growth rates (da/dN) of LZ50 axle steel. An equation for crack growth rate was derived to consider the trend of stress intensity factor range going down to the threshold and the average stress effect. The probabilistic models were presented on the equation. They consist of the probabilistic da/dN-ΔK relations, the confidence-based da/dN-ΔK relations, and the probabilistic- and confidence-based da/dN-ΔK relations. Efforts were made respectively to characterize the effects of probabilistic assessments due to the scattering regularity of test data, the number of sampling, and both of them. These relations can provide wide selections for practice. Analysis on the test data of LZ50 steel indicates that the present models are available and feasible.
基金financially supported by the National Natural Science Foundation of China(No.51274154)the National High-Tech Research and Development Program of China(No.2012AA03A504)+1 种基金the State Key Laboratory of Development and Application Technology of Automotive Steels(Baosteel Group)the Key Project of Hubei Education Committee,China(No.20121101)
文摘The growth rates of bainite plates in an Fe-C-Mn-Si superbainitie steel were investigated by in situ observation. The lengthening rates of ferrite bainite during both cooling and isothermal holding processes were observed and the growth rates of bainite plates nucleating at grain boundaries, within grains and on preformed bainite were measured. It is indicated that the lengthening rates of bainite plates during the cooling and isothermal processes were different, and that the growth rates of bainite plates nucleating at different types of sites also demon- strated diversity. The bainite plates initiating at [vain boundaries during cooling grew the fastest, while the plates nucleating on preformed bainite did the slowest. However, the growth rate of the bainite plates nucleating at grain boundaries during isothermal transformation de- creased the most, whereas the bainite plates initiating within grains grew the fastest. In addition, the growth rate of ferrite bainite in the study supported the diffusion transformation mechanism of bainite from the viewooint of ~rowth rate.
基金Project(2005CB623700) supported by the National Basic Research Program of China
文摘The effects of precipitates on the fatigue crack growth rate of AA 7055 Al alloy subjected to different ageing treatments were investigated using transmission electron microscope and fatigue crack growth testing.The results show that the T77 treated samples exhibit the lowest crack growth rate,while the crack growth rate of over-aged samples is the highest.In terms of the model based on the reversibility of dislocation motion within the plastic zone close to the crack tip,the improved crack growth resistance is attributed to many precipitates that are coherent with Al matrix in the under-aged and T77 treated samples.When the precipitate is coherent with the Al matrix,the larger the precipitate is,the slower the fatigue crack grows.The effects of grain boundary precipitates and precipitate free zone on the fatigue crack growth resistance are less significant than those of precipitates within grains of the alloy.
基金国家自然科学基金,Special Foundation of National Excellent Ph.D.Thesis,Outstanding Young Teachers of Ministry of Education of China
文摘Experimental study is performed on the probabilistic models for the long fatigue crack growth rates (da/dN) of LZ50 axle steel. An equation for crack growth rate was derived to consider the trend of stress intensity factor range going down to the threshold and the average stress effect. The probabilistic models were presented on the equation. They consist of the probabilistic da/dN-△K relations, the confidence-based da/dN-△K relations, and the probabilistic- and confidence-based da/dN-△K relations. Efforts were made respectively to characterize the effects of probabilistic assessments due to the scattering regularity of test data, the number of sampling, and both of them. These relations can provide wide selections for practice. Analysis on the test data of LZ50 steel indicates that the present models are available and feasible.
基金the supports from the Research Foundation for Visiting Scholars of Key Laboratory of Solid Mechanics and FML of Education Ministry,P R Chinathe supports from Japan Society for Promotion of Science
文摘Three types of fatigue tests for an annealed carbon steel containing carbon of 0.42%were carried out on smooth specimens and specimens with a small blind hole in order to investigate the fatigue crack growth law.A simple predicting method for crack growth rates has been proposed involving strengthσband the relation between cyclic stress and strain.The validity of proposed method has been confirmed by experiments on several carbon steels with different loadings.
基金the financial support from Consejo Nacional de Ciencia y Tecnología (CONACYT) Project N° 129780PAPIIT-UNAM project N° IN213912-3
文摘An Al-5.3%Zn-5.3%Mg alloy was unidirectionally solidified to determine morphological transition and solute distribution by a modification of the Bridgman technique for crystal growth with growth rates ranging from 4-500 μm/s and a temperature gradient of 25 K/cm. It was determined that growth rates from 6.5-9.5 μm/s generated a cell morphology, where the lower limit corresponds to the plane front to cellular transition and the upper limit indicates the cellular to columnar dendrite transition. The microstructures of the alloys solidified from 30 μm/s to growth rates less than 500 μm/s were mainly composed of columnar dendrites, while the microstructures solidified at growth rates greater than 500 μm/s were equiaxed. Regarding experimental results on solute distribution, a prediction of the model developed by Rappaz and Boettinger for dendrite solidification of multicomponent alloys was applied with excellent agreement. Results of solute distribution were employed to derive the precipitation fraction of τ-phase needed to increase the electrochemical properties of the alloy to be used as an Al-sacrificial anode.
基金Project supported by the National Natural Science Foundation of China(Nos.11672351 and11332007)the National Key R&D Plan(No.2016YFA0401200)the FengLei Youth Innovation Fund of China Aerodynamics Research and Development Center(No.KT-FLJJ-201803)
文摘The elementary task is to calculate the growth rates of disturbances when the e;method in transition prediction is performed. However, there is no unified knowledge to determine the growth rates of disturbances in three-dimensional(3 D) flows. In this paper, we study the relation among the wave parameters of the disturbance in boundary layers in which the imaginary parts of wave parameters are far smaller than the real parts.The generalized growth rate(GGR) in the direction of group velocity is introduced, and the conservation relation of GGR is strictly deduced in theory. This conservation relation manifests that the GGR only depends on the real parts of wave parameters instead of the imaginary parts. Numerical validations for GGR conservation are also provided in the cases of first/second modes and crossflow modes. The application of GGR to the eN method in 3 D flows is discussed, and the puzzle of determining growth rates in 3 D flows is clarified. A convenient method is also proposed to calculate growth rates of disturbances in 3 D flows. Good agreement between this convenient method and existing methods is found except the condition that the angle between the group velocity direction and the x-direction is close to 90?which can be easily avoided in practical application.