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Simultaneous, Asymmetrical, Comminuted and Bilateral Ballistic Fractures by Multiple Gunshot Wounds and a Review of Its Literature: A Case Report in Chad
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作者 Siniki Fandebnet Ngamai Kotyade +5 位作者 Adamou Abbasi Dingamnodji Magloire Mahamat Bahar Abdelsalam Yusra Aboulbachar Assi Constant Andre Daniel Sane 《Open Journal of Orthopedics》 2022年第10期377-382,共6页
Although open leg fractures are very common in orthopedics and traumatology, bilateral open leg fractures are extremely rare and are usually associated with an increased risk of complications. We report a case of a si... Although open leg fractures are very common in orthopedics and traumatology, bilateral open leg fractures are extremely rare and are usually associated with an increased risk of complications. We report a case of a simultaneous, asymmetrical, comminuted and bilateral open fracture of the tibia and fibula by a firearm that occurred during an escape attempt in a 29-year-old prisoner. The pre-operative radiological assessment found an open fracture of both legs of the ballistic type;multiple traumatic gunshot wounds with a narrow entry hole and a wide exit hole. Early surgical intervention of intravenous antibiotics, tetanus prophylaxis and open fracture irrigation and debridement was performed within the 6 hour rule. The treatment consisted of a posterior splint followed by trimming andosteosynthesis using a FESSA external fixator from the military health service. A second operation was not needed. Evolution was favorable with ambulation starting from the 45th day. Simultaneous and bilateral tibia-fibula fractures by a firearm are exceptional, therefore, the treatment was surgical with the pre-operative and post-operative protocols well managed. 展开更多
关键词 Simultaneous Bilateral Tibia-Fibula Fractures gunshot wounds External Fixator Ballistic Fractures
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Civilian gunshot wounds to the head:a case report,clinical management,and literature review 被引量:1
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作者 Haoyi Qi Kunzheng Li 《Chinese Neurosurgical Journal》 CSCD 2021年第3期216-224,共9页
Background:Civilian gunshot wounds to the head refer to brain injury caused by projectiles such as gun projectiles and various fragments generated by explosives in a power launch or explosion.Gunshot wounds to the hea... Background:Civilian gunshot wounds to the head refer to brain injury caused by projectiles such as gun projectiles and various fragments generated by explosives in a power launch or explosion.Gunshot wounds to the head are the deadliest of all gun injuries.According to literature statistics,the survival rate of patients with gunshot wounds to the head is only 9%.Due to the strict management of various types of firearms,they rarely occur,so the injury mechanism,injury and trauma analysis,clinical management,and surgical standards are almost entirely based on military experience,and there are few related reports,especially of the head,in which an individual suffered a fatal blow more than once in a short time.We report a case with a return to almost complete recovery despite the patient suffering two gunshot injuries to the head in a short period of time.Case presentations:We present a case of a 53-year-old man who suffered two gunshot injuries to the head under unknown circumstances.On initial presentation,the patient had a Glasgow Coma Scale score of 6,was unable to communicate,and had loss of consciousness.The first bullet penetrated the right frontal area and finally reached the right occipital lobe.When the patient reflexively shielded his head with his hand,the second bullet passed through the patient’s right palm bone,entered the right frontotemporal area,and came to rest deep in the lateral sulcus.The patient had a cerebral hernia when he was admitted to the hospital and immediately entered the operating room for rescue after a computed tomography scan.After two foreign body removals and skull repair,the patient recovered completely.Conclusions:Gunshot wounds to the head have a high mortality rate and usually require aggressive management.Evaluation of most gunshot injuries requires extremely fast imaging examination upon arrival at the hospital,followed by proactive treatment against infection,seizure,and increased intracranial pressure.Surgical intervention is usually necessary,and its key points include the timing,method,and scope of the operation. 展开更多
关键词 gunshot wound Head trauma Penetrating brain injury Traumatic brain injury
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Surgical treatment for rabbits' femoral arteries subjected to gunshot wounds combining with seawater immersion 被引量:4
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作者 刘鹏 彭学良 +4 位作者 刘晋才 赖西南 张良潮 吴国萍 王丽丽 《Chinese Journal of Traumatology》 CAS 2005年第5期311-316,共6页
Objective: To investigate the surgical treatment methods and evaluate the outcome of gunshot wounds combining with seawater immersion in rabbits’ femoral arteries. Methods: One hundred healthy New Zealand white rabbi... Objective: To investigate the surgical treatment methods and evaluate the outcome of gunshot wounds combining with seawater immersion in rabbits’ femoral arteries. Methods: One hundred healthy New Zealand white rabbits (either sex, 3.14 kg± 0.61 kg in weight) were randomly divided into a seawater immersion group (n=50) and a simple injury group (n=50). The unilateral femoral arteries of all the rabbits were injured by 0.38 g steel spheres with velocity of 600-800 m/s fired by a 7.62 mm rifle. The rabbits in the seawater immersion group were immersed in seawater (saline content of 2.54%, pH 8.2- 8.4, and at 21℃) for 60 minutes but those in the simple injury group were not. After the injured segment (observed by naked eyes) of the femoral artery was excised, the blood flow restoration was reconstructed by direct end-to-end anastomosis, reversed autogenous venous grafting or cryopreserved arterial allografting, according to the length of the arterial defects. At 24 hours, and 7, 14 and 21 days after operation, the blood flow was examined. Operative exploration was performed for the animals with partly or fully obstructed blood flow. The tissues around the anastomosis sites and the grafts were harvested for pathological observation under a light microscope and an electron microscope. Results: In the rabbits with completely transected injury, the unobstructed rates in the first 3 weeks after operation were 80.00% in the seawater immersion group and 86.67% in the single injury group, and no significant difference was found between the two groups (P> 0.1). In the rabbits with arterial contusion injury, the unobstructed rates in the first 3 weeks after operation were 86.67% in the seawater immersion group and 82.35% in the single injury group, and no significant difference was found between the two groups (P> 0.1). Most thrombosis occurred in the first operative week. Atypical endothelial cells were detected at the anastomosis sites at the first operative week, and the anastomosis sites were lined with endothelial cells in 3 weeks postoperatively. Conclusions: During the surgical treatment for gunshot wounds combining with seawater immersion, resection of the grossly-injured artery and routine artery reconstruction can obtain satisfactory outcome. Homologous artery is a kind of vascular graft with certain applied value. 展开更多
关键词 手术治疗 动脉疾病 创伤 海水浸泡 动脉通道
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Pathological study of rabbits' femoral arteries subjected to gunshot wounds combining with seawater immersion 被引量:2
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作者 刘鹏 刘晋才 +4 位作者 赖西南 彭学良 吴国萍 张良潮 王丽丽 《Chinese Journal of Traumatology》 CAS 2005年第3期186-190,共5页
Objective: To investigate pathological characteristics of gunshot wounds concomitant seawater immersion in rabbits’ femoral arteries. Methods: Thirty rabbits were divided randomly into 3 groups: simple gunshot-wound ... Objective: To investigate pathological characteristics of gunshot wounds concomitant seawater immersion in rabbits’ femoral arteries. Methods: Thirty rabbits were divided randomly into 3 groups: simple gunshot-wound group (Group I, n=10), gunshot wound with seawater immersion for 30 mins (Group II, n=10), and 60 mins group (Group III, n=10). Femoral arteries were impacted by (0.38 g) steel spheres fired with a (7.62 mm) rifle. After being wounded, rabbits in Groups II and III were immersed in seawater for 30 or 60 mins, but those in Group I were not. At 2, 4, 6, 8, 12 hours following injury, a 40 mm segment of the artery on each side of the gunshot point were excised and observed by light and electron microscopy. Results: The patterns of arterial injuries were mainly contusion and transection. Completely transected artery was classified as primary-wound-tract area, contused area and shocked area. Compared with those in Group I, the primary-wound-tract and contused areas in Group II manifested obvious swelling in the arterial wall especially at the outside 2/3 of the media. Vacuolar structures were often seen in smooth muscle cells of the media. Intercellular space among the smooth muscle cells were filled with homogeneous acidophilic substances. Deep rugae among endothelial cells flattened or rugal folds lost their longitudinal orientation, and marked fibrin and platelet deposition were noticed. No significant difference was detected between Group II and III. The pathological changes in the shocked area were similar in 3 groups. Conclusions: For gunshot wounds concomitant seawater immersion in rabbits’ femoral arteries, there was a marked swelling of cells and intercellular space in primary-wound-tract area and contusion area. The influence of these pathological changes on surgical reparation deservers further study. 展开更多
关键词 病理学 动物实验 股动脉 炮伤 海水沉浸
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损害控制手术治疗高原寒冷环境猪腹部枪击肠管贯通伤的效果评价
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作者 孙赳 杨雪 +3 位作者 屈金权 杨欣悦 李佳佳 刘江伟 《创伤外科杂志》 2024年第6期410-417,共8页
目的观察损害控制手术(DCS)与传统手术对于高原寒冷环境下猪腹部枪击肠管贯通伤的救治效果。方法本文前瞻性研究,将30头10~12周龄健康长白仔猪,随机分为3组(各10只),分别为高原致伤组(HI)、高原致伤+传统手术组(HIT)、高原致伤+DCS组(H... 目的观察损害控制手术(DCS)与传统手术对于高原寒冷环境下猪腹部枪击肠管贯通伤的救治效果。方法本文前瞻性研究,将30头10~12周龄健康长白仔猪,随机分为3组(各10只),分别为高原致伤组(HI)、高原致伤+传统手术组(HIT)、高原致伤+DCS组(HID)。通过将仔猪放入模拟高原寒冷环境的西北地区特殊环境人工实验舱[设置舱内海拔6000 m,气压约4.7 kPa,温度(8±2)℃,模拟高原低压、低氧、寒冷环境]48 h,并使用警用制式QSZ92式手枪,9 mm手枪弹射击脐水平后方2 cm,右侧腹壁皱襞下缘交界处目标点制作高原寒冷环境猪腹部枪击肠管贯通伤模型。HI组受伤后予以伤口包扎后观察处理。HIT组伤后4 h予以断裂小肠或缺血坏死小肠切除后行肠管端端吻合的传统手术治疗。HID组伤后4 h行断裂小肠近端置入减压管,远端小肠封闭;连续多处穿孔小肠或缺血坏死小肠切除,近端置入减压管,远端小肠封闭的DCS治疗。分别观察并比较各组伤后不同时间一般情况、生命体征、手术相关指标,WBC、中性粒细胞计数(NEUT)、IL-6、TNF-α、ALT、AST、并发症发生率、存活率。结果HIT组和HID组的小肠挫伤、小肠破裂、肠系膜损伤、结肠破裂、弹孔直径、腹腔积血无明显差异(P>0.05)。HID组12 h开始呼吸(25.2±4.0)次/min、心率(129.9±9.8)次/min、体温(38.3±0.6)℃显著低于HI组[呼吸(38.7±4.7)次/min、心率(150.3±8.6)次/min、体温(40.2±1.0)℃]和HIT组[呼吸(32.0±4.0)次/min、心率(143.6±11.4)次/min,体温(38.8±0.6)℃];HID组48 h体温低于HIT组[(38.3±0.6)℃vs.(39.6±0.6)℃],差异有统计学意义(P<0.05),生命体征更快达到平稳状态。HID组的手术时间、呼吸恢复时间、拔管时间、自由活动时间和首次排便时间显著短于HIT组[(46.00±9.37)min vs.(146.00±14.68)min、(26.20±4.24)min vs.(46.10±3.84)min、(45.40±3.03)min vs.(95.70±3.30)min、(96.90±4.48)min vs.(198.20±4.80)min、(27.90±7.80)h vs.(47.99±5.41)h];术中失血量及输液量少于HIT组(P<0.05)。HID组12 h开始WBC(18.4±4.8)×10^(9)/L、NEUT(3.3±1.1)×10^(9)/L、IL-6(110.4±8.7)pg/mL、TNF-α(288.5±16.4)×10^(9)/L低于HI组[WBC(56.6±9.3)×10^(9)/L、NEUT(24.0±4.4)×10^(9)/L、IL-6(158.8±16.0)pg/mL、TNF-α(425.4±35.3)pg/mL];HID组WBC和NEUT于12 h起低于HIT组;IL-6于24 h起低于HIT组;TNF-α于48 h起低于HIT组(P<0.05)。HID组12 h开始ALT、AST低于HI组[(88.4±9.9)U/L vs.(138.1±14.4)U/L、(110.4±8.8)U/L vs.(210.1±11.6)U/L];HID组24 h开始ALT、AST低于HIT组[(66.6±14.0)U/L vs.(82.0±8.3)U/L、(96.4±8.9)U/L vs.(10^(9).7±9.9)U/L],P<0.05。HID组术后发热、切口出血、切口皮肤淤斑、肠漏发生率低于HIT组(P<0.05)。HI组、HIT组、HID组72 h存活率分别为60%、70%、100%。HID组生存曲线优于HI组(P<0.05)。结论与传统手术治疗比较,伤后早期行DCS治疗,可缩短手术时间,减少术中出血,加快麻醉苏醒,促进术后早期胃肠道功能恢复及活动,降低手术并发症,改善仔猪生命体征、血清炎症因子水平、生存时间,提示DCS是早期治疗高原寒冷环境腹部枪击肠管贯通伤的有效方法。 展开更多
关键词 肠管贯通伤 枪击伤 损害控制手术 高原寒冷环境
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Temporary Cavity Effects of High Velocity Spherical Steel Bullet Wounds in Maxillofacial Region of Dogs
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作者 华泽权 周树夏 +1 位作者 刘荫秋 刘志斌 《Journal of Medical Colleges of PLA(China)》 CAS 1990年第2期168-170,175,共4页
Maxillofacial region wounds of dogs were inflicted by spherical steel bullets,0.7 g weight,with the muzzle velocity of 1.3 km/s.The photographs of the temporarycavity were taken with a high speed x-ray cine-camera,and... Maxillofacial region wounds of dogs were inflicted by spherical steel bullets,0.7 g weight,with the muzzle velocity of 1.3 km/s.The photographs of the temporarycavity were taken with a high speed x-ray cine-camera,and local wounding conditionswere observed with the naked eye.The experimental results proved that a temporary ca-vity was formed in the maxillofacial region wound.The contusion zone of the maxillofa-cial soft tissue was smaller than that of the extremities.The contusion zone of the skinand oral mucous membrane was 1-2 mm,and that of muscle was 5-8 mm in thickness.In clinical situation,the tissues of the contusion zones should always be excised since itconsists of devitalized tissue.The temporary cavitation is an important factor in causingstructural injuries of tissues around the local wound track. 展开更多
关键词 MAXILLOFACIAL fegion wound gunshot cavity effect
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Pathological Changes of Small Blood Vessels in Maxillofacial Region Following High Velocity Missile Wound:an Experimental Study in Dogs
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作者 谭颖徽 周树夏 +3 位作者 刘宝林 刘荫秋 程学明 赖西南 《Journal of Medical Colleges of PLA(China)》 CAS 1990年第3期232-236,共5页
In order to provide an experimental foundation and pathological base for earlyreconstruction of maxillofacial tissues defects after firearms wound using microsurgicalmethods,an experiment,was made to study the microva... In order to provide an experimental foundation and pathological base for earlyreconstruction of maxillofacial tissues defects after firearms wound using microsurgicalmethods,an experiment,was made to study the microvascular pathological changesthrough light and electron microscopy observation.In the experiment we found somepathological changes of small vessels in wounded region,such as mierothrombi forma-tion,endothelial loss,internal elastic membrane break and some degenerations,necrosis within endothelial and smooth muscle cells of vessel.The nearer the woundededge was,the more evident injury was.The microvascular injurous range was 3 cm dis-tant from wounded edge,which recovered in 7 days later after wounding.The experi-ment indicated that if we used the vascularized free tissue transfer to repair defects ofmaxillofacial firearms wounds,the pedicles of flap should be anastomosed to distant re-cipient vesseles which could be chosen beyond 3 cm from wounded edge.Thereconstructive operation should be done 7 days later after wound. 展开更多
关键词 wound gunshot MAXILLOFACIAL SMALL vessel pathology
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Internal Fixation of Gunshot Induced Fractures in Civilians: Anatomic and Functional Results of a Standard Protocol at an Urban Trauma Center
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作者 Anani Abalo Atsi Walla +3 位作者 Gamal Ayouba Yaovi Yannick Dellanh Kosivi Fortey Assang Dossim 《Open Journal of Orthopedics》 2016年第3期63-70,共8页
Introduction: Despite extensive experience with civilian gunshot fractures or wounds, no consensus exists on a standard protocol to manage these injuries. Many authors recommended immediate debridement, but the optima... Introduction: Despite extensive experience with civilian gunshot fractures or wounds, no consensus exists on a standard protocol to manage these injuries. Many authors recommended immediate debridement, but the optimal timing of internal fixation and the use of antibiotic have not been determined. The purpose of this paper is to present and discuss our experience. Material and methods: In January 2007, a treatment protocol was put in place for the evaluation and management of fractured extremities resulting from civilian gunshot wounds. Sixty-three patients with 64 fractures had been managed by this protocol for gunshot fractures between January 2005 and January 2012. There were 56 male and seven female. Their mean age was 33.1 years (range: 17 - 61 years). Thirteen patients (20.6%) were able to provide a description of the weapon. Only 15 patients had entry and exit wounds. The mean follow-up period was 27 (range, 20 - 58) months. The main factors assessed were the surgical site infection, the fracture union and the functional status. Results: Out of the 63 patients, 14 patients developed a wound infection (five superficial and seven deep infections). Wound infection was significantly associated with associated injuries (p = 0.0388), fractures sites requiring fixation (p = 0.024), the fracture pattern (p = 0.0412), operative modalities (p = 0.0400). There were nine cases (14.1%) of fracture non-union. The mean time to union was 15 weeks (range: 5 - 32 weeks). Five patients developed chronics osteomyelitis. The average SMFA score for all of the patients was 23.8 (range: 0 - 56.3). The mean dysfunctional and bother indexes were 18.3 (range: 0 - 52.7) and 22.6 (range: 0 - 66.1), respectively. The SMFA total score and dysfunction index had a significant correlation based on presence or absence of associated injuries (p < 0.0001). But bother index did not show the same correlation (p = 0.452). The average length of hospital stay was 11.3 days (range: 3 - 64). Conclusion: In civilian’s gunshot induced fractures, internal fixation can be made according to standard protocol, with acceptable result. 展开更多
关键词 FRACTURE gunshot Fracture Internal Fixation wound Infection Surgical Treatment
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Masquelet technique in military practice:specificities and future directions for combat-related bone defect reconstruction
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作者 Laurent Mathieu Romain Mourtialon +3 位作者 Marjorie Durand Arnaud de Rousiers Nicolas de l’Escalopier Jean‑Marc Collombet 《Military Medical Research》 SCIE CAS CSCD 2023年第3期369-382,共14页
Because of its simplicity,reliability,and replicability,the Masquelet induced membrane technique(IMT)has become one of the preferred methods for critical bone defect reconstruction in extremities.Although it is now us... Because of its simplicity,reliability,and replicability,the Masquelet induced membrane technique(IMT)has become one of the preferred methods for critical bone defect reconstruction in extremities.Although it is now used worldwide,few studies have been published about IMT in military practice.Bone reconstruction is particularly challenging in this context of care due to extensive soft-tissue injury,early wound infection,and even delayed management in austere conditions.Based on our clinical expertise,recent research,and a literature analysis,this narrative review provides an overview of the IMT application to combat-related bone defects.It presents technical specificities and future developments aiming to optimize IMT outcomes,including for the management of massive multi-tissue defects or bone reconstruction performed in the field with limited resources. 展开更多
关键词 Bone defect Induced membrane technique gunshot wound Low resources Masquelet technique MILITARY War surgery
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腹臀部贯通枪伤1例诊治体会
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作者 刘蒸 罗岚 廖建 《外科研究与新技术》 2023年第1期66-68,共3页
由于我国枪支管制,相关临床实践经验欠缺,本文特报告腹臀部的贯通枪伤1例,并对腹部的火器伤的手术指征的判断、手术原则及相关处理要点进行讨论,为普外科医师处理腹部枪伤提供帮助。
关键词 枪伤 贯通伤 腹部损伤
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一起变造射钉枪走火致人死亡案的模拟实验
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作者 毛文智 赵晔 霍起森 《刑事技术》 2023年第5期547-550,共4页
因枪支机件陈旧松散、保险机件失灵导致枪支在拆卸、擦拭、触摸、磕碰等过程中引起走火是较为常见的枪支走火原因。本文介绍了一起因变造射钉枪裸露击发扳机受到包裹物撞击引起走火而致人死亡的案件,结合现场勘查及尸体检验的意见,对死... 因枪支机件陈旧松散、保险机件失灵导致枪支在拆卸、擦拭、触摸、磕碰等过程中引起走火是较为常见的枪支走火原因。本文介绍了一起因变造射钉枪裸露击发扳机受到包裹物撞击引起走火而致人死亡的案件,结合现场勘查及尸体检验的意见,对死者枪创的形成方式及变造射钉枪能否走火等问题进行了模拟实验。通过实验的方法还原了枪支走火的全过程,分析讨论了变造射钉枪走火的规律、特点,能为类似案件侦办提供参考。 展开更多
关键词 变造枪支 射钉枪 人体枪创 形成方式 包裹物 走火 模拟实验
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以动物模型为基础的颅脑战伤损伤控制手术模拟训练
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作者 钟鑫 宗兆文 +4 位作者 贾益君 蒋仁庆 叶钊 周小林 杜文琼 《海军医学杂志》 2023年第7期667-671,共5页
目的为提高基层军医颅脑战伤损伤控制手术能力,采用枪弹伤动物模型进行模拟训练。方法以自行研发的实验动物致伤平台为基础,将家猪固定于致伤仪器上,瞄准眼角眶上缘0.5 cm处进行致伤,制成颅脑枪弹伤动物模型,根据实际伤情完成颅脑战伤... 目的为提高基层军医颅脑战伤损伤控制手术能力,采用枪弹伤动物模型进行模拟训练。方法以自行研发的实验动物致伤平台为基础,将家猪固定于致伤仪器上,瞄准眼角眶上缘0.5 cm处进行致伤,制成颅脑枪弹伤动物模型,根据实际伤情完成颅脑战伤损伤控制手术。在一线救治能力建设试点、任职培训班、整建制基地化训练等任务中进行应用。结果开展以动物模型为基础的颅脑战伤损伤控制手术模拟训练后,学员成绩提高了17.48%。结论野战医疗队的手术能力强于严重创伤损伤控制手术和复苏培训班手术组,更是强于一线救治能力建设试点单位基层部队手术组。本研究建立的动物模型及模拟训练流程有利于提高基层军医颅脑战伤损伤控制手术能力。 展开更多
关键词 颅脑战伤 损伤控制手术 动物模型 枪弹伤 训练流程
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高压氧治疗海水浸泡火器伤兔股骨骨缺损的疗效观察
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作者 张淦 刘胜杰 +3 位作者 王智 陈聪聪 马武秀 陈肖松 《安徽医药》 CAS 2023年第5期999-1002,I0004,共5页
目的 观察高压氧治疗海水浸泡火器伤所致兔股骨开放性骨缺损的疗效。方法 实验实施时间2020年7月至2021年5月。84只新西兰兔采用随机数字表法分成对照组和高压氧组。制作海水浸泡火器伤所致肢体开放性骨缺损模型,对照组彻底清创后,行骨... 目的 观察高压氧治疗海水浸泡火器伤所致兔股骨开放性骨缺损的疗效。方法 实验实施时间2020年7月至2021年5月。84只新西兰兔采用随机数字表法分成对照组和高压氧组。制作海水浸泡火器伤所致肢体开放性骨缺损模型,对照组彻底清创后,行骨折切开复位钢板内固定术;高压氧组彻底清创后,行骨折切开复位钢板内固定术,连续高压氧治疗7 d。通过X线摄片、定量PCR法、HE染色及生物力学分析评价各组治疗效果。结果 血管内皮生长因子(VEGF) mRNA各组各个时间段均有表达,与对照组相比,高压氧组术后1 d[(2.97±0.25)比(2.39±0.24)]、3 d[(4.12±0.38)比(3.65±0.30)]、1周[(4.83±0.23)比(4.36±0.39)]、2周[(5.89±0.40)比(5.04±0.36)]、4周[(4.21±0.42)比(5.04±0.36)],差异有统计学意义(P<0.05);术后8周、12周,两组VEGF mRNA表达,差异无统计学意义(P>0.05)。影像学观察:术后2周两组未见明显骨组织影,钢板及螺钉在位。术后4周两组骨缺损区有薄云状骨痂阴影,阴影区域高压氧组>对照组,钢板及螺钉在位。术后8周对照组骨组织阴影增强,高压氧组达骨性愈合,髓腔未完全再通,钢板及螺钉在位。术后12周,对照组达骨性愈合,但髓腔部分再通,钢板及螺钉在位;高压氧组皮质连续性好,髓腔再通,基本完成修复,钢板及螺钉在位。Lane-Sandhu放射学评分,与对照组相比,高压氧组术后4周[(4.17±0.75)分比(2.83±0.98)分]、8周[(7.67±1.63)分比(5.67±0.82)分]、12周[(10.17±1.47)分比(7.83±1.17)分],差异有统计学意义(P<0.05);术后2周,两组Lane-Sandhu放射学评分,差异无统计学意义(P>0.05)。组织学观察:术后第12周,两组大量板层骨形成,对照组髓腔部分再通,高压氧组髓腔再通。生物力学分析:对照组最大负荷(195.97±11.70)N<高压氧组最大负荷(239.75±10.76)N,差异有统计学意义(P<0.05)。结论 高压氧具有促进海水浸泡火器伤致骨缺损愈合的作用。 展开更多
关键词 高压氧 创伤 枪击 海水浸泡 兔股骨骨缺损 火器伤
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高原高寒战时环境猪肢体枪弹伤后T-AOC、SOD、MDA的特点变化及意义 被引量:23
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作者 殷作明 胡德耀 +7 位作者 李素芝 叶峰 石权贵 宋俊 刘良明 杨志焕 陈永龙 刘安 《第三军医大学学报》 CAS CSCD 北大核心 2005年第9期809-812,共4页
目的 探讨高原高寒环境下平战时肢体火器伤后血浆及伤道组织中总抗氧化能力(T AOC)、超氧化物歧化酶(SOD)、丙二醛(MDA)含量变化的规律。方法 将2 4头实验猪随机分为高原战时致伤组(GZ)、高原平时致伤组(GP)和平原平时致伤组(PP) ,每... 目的 探讨高原高寒环境下平战时肢体火器伤后血浆及伤道组织中总抗氧化能力(T AOC)、超氧化物歧化酶(SOD)、丙二醛(MDA)含量变化的规律。方法 将2 4头实验猪随机分为高原战时致伤组(GZ)、高原平时致伤组(GP)和平原平时致伤组(PP) ,每组8头,在不同环境下致伤;分别于伤前、伤后不同时相点采集中静脉血和伤道肌肉组织定量测定T AOC、SOD、MDA。结果 ①平原平时组血浆和伤道组织内T AOC伤后均持续下降,在伤后1~2d降至最低点,此后逐渐上升;SOD、MDA均在伤后3 0min~2h即有升高,至6h时达最高点,此后逐渐下降,组织中3d恢复到较低水平,血浆中5d恢复至正常水平。②高原平时组血浆和伤道组织内T AOC、SOD、MDA变化规律与平原平时组相似,但变化的幅度大、持续的时间长。③高原战时组与高原平时组相比,血浆和伤道组织内T AOC在伤前即有显著降低,SOD、MDA显著增高,伤后各指标升高或降低的程度、持续时间均显著高于高原平时组,峰值出现的时间也有所提前。结论 高原高寒战时环境猪肢体枪弹伤后全身和局部伤道组织的损伤程度重于高原平时组,而高原平时组的损伤又重于平原平时组。 展开更多
关键词 高海拔 高寒 战争环境 枪弹伤 总抗氧化能力 超氧化物歧化酶 丙二醛
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狗颅脑爆炸伤后脑组织中TNF-αmRNA表达的变化 被引量:8
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作者 侯立军 张光霁 +7 位作者 卢亦成 朱诚 刘荫秋 李兵仓 赖西南 李曙光 李薇 蔡文琴 《第二军医大学学报》 CAS CSCD 北大核心 2001年第6期551-553,F003,共4页
目的 :探讨狗颅脑爆炸伤后脑组织中 TNF-α m RNA的变化及其规律。方法 :应用原位杂交技术分别检测狗颅脑爆炸伤后 30 min和 1、3、6 h大脑皮质、海马、下丘脑和脑干等不同脑区脑组织中 TNF-α m RNA的表达情况 ,并与正常对照组比较。... 目的 :探讨狗颅脑爆炸伤后脑组织中 TNF-α m RNA的变化及其规律。方法 :应用原位杂交技术分别检测狗颅脑爆炸伤后 30 min和 1、3、6 h大脑皮质、海马、下丘脑和脑干等不同脑区脑组织中 TNF-α m RNA的表达情况 ,并与正常对照组比较。应用电子计算机图像分析技术对其结果进行半定量分析。结果 :正常对照组狗脑组织内 TNF-α m RNA即有表达 ;颅脑爆炸伤后不同脑区脑组织中 TNF-α m RNA的表达量均明显升高 ,变化幅度以大脑皮质挫伤区和同侧海马最为显著。 TNF-αm RNA在伤后 30 m in表达量即明显增加 ,至伤后 1h达到高峰 ,伤后 3h呈下降趋势 ,但仍高于正常水平。伤侧大脑半球TNF- α m RNA的表达量明显高于对侧大脑半球。结论 :TNF- α m RNA在生理状态下即有表达 ,TNF- α参与正常的生理功能 ;颅脑爆炸伤后早期脑组织中 TNF- α的表达增多 ,提示 TNF- 展开更多
关键词 脑损伤 火器伤 肿瘤坏死因子 mRNA TNFΑ
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火器伤初期外科处理的病理学研究 被引量:13
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作者 章亚东 侯树勋 +1 位作者 张伟佳 盛志勇 《解放军医学杂志》 CAS CSCD 北大核心 1995年第3期190-192,共3页
对犬火器伤模型分别采用传统的切除失活组织(切除)和现代的仅强调减压、引流(切开)的初期外科处理方法,对其病理形态学及细菌学等资料作了系统观察。结果发现:两种方法对感染等并发症的防治效果没有显著性差异,而在对创伤修复的... 对犬火器伤模型分别采用传统的切除失活组织(切除)和现代的仅强调减压、引流(切开)的初期外科处理方法,对其病理形态学及细菌学等资料作了系统观察。结果发现:两种方法对感染等并发症的防治效果没有显著性差异,而在对创伤修复的影响方面,切开法明显较切除法优越。 展开更多
关键词 火器伤 切除法 切开法 外科手术 病理学
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枪弹伤所致血流动力学变化对远隔脏器损伤作用的临床意义 被引量:9
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作者 李曙光 刘荫秋 +7 位作者 王建民 安波 陈菁 练伟坤 王大田 赖西南 吴国萍 陈志强 《医用生物力学》 CAS CSCD 1996年第3期136-139,共4页
本文以五六式7.62mm和5.56mmM193两种枪弹对狗和模拟介质射击为致伤模型,以高速摄影、瞬态测压和病理解剖等手段,观察了致伤瞬间血管移位变形和不同管径内压力呈梯度衰减规律,并证实了致伤瞬间确有血流扰动的存在,... 本文以五六式7.62mm和5.56mmM193两种枪弹对狗和模拟介质射击为致伤模型,以高速摄影、瞬态测压和病理解剖等手段,观察了致伤瞬间血管移位变形和不同管径内压力呈梯度衰减规律,并证实了致伤瞬间确有血流扰动的存在,结合远端组织脏器的病理变化特点,阐明了远隔脏器的损伤与致伤瞬间所致血流剧烈扰动的强度之间的关系,为判定严重创伤并发症发生发展的规律提供理论依据。 展开更多
关键词 枪弹伤 远达效应 血流扰动 血液动力学
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寒冷干燥环境中肢体火器伤伤道细菌种类分析 被引量:7
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作者 陈建常 严耘 +5 位作者 史振满 彭江 季明华 许刚 李莉 刘霞 《中国现代医学杂志》 CAS CSCD 2003年第4期20-22,共3页
目的 :探讨寒冷干燥环境下 ,肢体火器伤细菌种类与药敏试验。方法 :用 2 4只兔的后肢制作成寒冷干燥环境下火器伤模型 ,于伤后 1、3、6、12、2 4、4 8、72、96h进行生命体征观察、伤道分泌物细菌培养、分类及药物敏感试验 ,同时对动物... 目的 :探讨寒冷干燥环境下 ,肢体火器伤细菌种类与药敏试验。方法 :用 2 4只兔的后肢制作成寒冷干燥环境下火器伤模型 ,于伤后 1、3、6、12、2 4、4 8、72、96h进行生命体征观察、伤道分泌物细菌培养、分类及药物敏感试验 ,同时对动物皮毛、耙场空气等进行了细菌培养和分类。结果 :伤后动物呼吸、脉搏加快 ,体温下降 ,致伤后 2 4h呼吸、脉搏恢复正常 ,但体温仍低于致伤前 ;伤道分泌物细菌培养主要为G+ 菌 ,其次为G-菌 ,这些细菌对红霉素、丁胺卡那霉素、头孢类和喹诺酮类抗生素最敏感 ,对复方新诺明耐药 ,部分G-菌对青霉素、庆大霉素耐药。结论 :寒冷干燥环境下火器伤伤道细菌繁殖慢 ,伤道感染及细菌入血时间推后 ,认为这种特殊环境条件下的火器伤早期伤道清创时限可适当推迟 ,强调抗生素的使用应结合地域环境、气候条件等特点 ,早期联合使用抗生素。 展开更多
关键词 寒冷 干燥 火器伤 细菌学 抗生素 细菌种类 药物敏感试验
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犬脑枪弹伤模型建立及相关生理、病理指标观察 被引量:18
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作者 封亚平 章翔 +4 位作者 费舟 吴景文 武弋 宋少军 顾建文 《第四军医大学学报》 北大核心 2002年第23期2145-2148,共4页
目的 建立犬脑枪弹伤致伤模型 ,检验该模型用于颅脑枪弹伤进一步研究的可行性 .方法 杂种犬 14只 ,随机分成脑贯通伤 (PCI)组 (n =7)和脑切线伤 (TBI)组 (n =7) ,采用德国小口径步枪子弹按上述分组要求致伤 .测定弹丸致伤参数 ,观察... 目的 建立犬脑枪弹伤致伤模型 ,检验该模型用于颅脑枪弹伤进一步研究的可行性 .方法 杂种犬 14只 ,随机分成脑贯通伤 (PCI)组 (n =7)和脑切线伤 (TBI)组 (n =7) ,采用德国小口径步枪子弹按上述分组要求致伤 .测定弹丸致伤参数 ,观察实验犬伤后相关生理与病理指标改变 .结果 TBI组和PCI组的弹丸撞击速度与撞击能量基本一致 ;TBI组的组织对弹丸吸收能量较大 (P <0 0 5 ) ,且实验犬伤后存活时间也较长(P =0 0 0 13) .两组犬均在伤后数分钟至 1h内出现明显的心率减慢、血压下降、颈动脉血流量减少、呼吸暂停或减慢、颅内压 (ICP)逐渐升高 .两组挫伤区病理表现为脑血管扩张、充血、血管周围环形出血、神经细胞轻度缺血、坏死及脑水肿 .结论 上述模型均具有弹道伤恒定、重复性好、伤后动物存活时间较长等特点 。 展开更多
关键词 脑枪弹伤 致伤能量 病理生量学 动物模型
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枪弹所致血流强扰动后血液流变学变化及其对伤情转归的影响 被引量:5
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作者 李曙光 王建民 +7 位作者 刘荫秋 陈志强 王大田 张良潮 练伟伸 赖西南 吴国萍 陈蕾 《生物医学工程学杂志》 EI CAS CSCD 北大核心 1998年第1期49-52,共4页
采用M193556mm枪弹对犬双后肢致伤、双侧股动静脉结扎后致伤及单纯放血致休克三组实验模型,重点观察了血液流变学发生的一系变化特点,分析探讨了其在伤情转归中的作用。结果表明:高速投射物所产生的血流强烈扰动,可导致... 采用M193556mm枪弹对犬双后肢致伤、双侧股动静脉结扎后致伤及单纯放血致休克三组实验模型,重点观察了血液流变学发生的一系变化特点,分析探讨了其在伤情转归中的作用。结果表明:高速投射物所产生的血流强烈扰动,可导致全血粘度急剧增高、红细胞聚集增加及血液浓缩等流变学变化,可能与血流强烈扰动造成血管内皮细胞损伤以及血液中细胞成分的破坏有关。上述变化可导致微循环的改变和物质传输的紊乱,进而为严重并发症的发生发展提供病理生理基础。 展开更多
关键词 枪弹伤 血流强扰 血液流变学 伤情转归 失血性休克 并发症
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