Grid integration of wind power is essential to reduce fossil fuel usage but challenging in view of the intermittent nature of wind.Recently,we developed a hybrid Markovian and interval approach for the unit commitment...Grid integration of wind power is essential to reduce fossil fuel usage but challenging in view of the intermittent nature of wind.Recently,we developed a hybrid Markovian and interval approach for the unit commitment and economic dispatch problem where power generation of conventional units is linked to local wind states to dampen the effects of wind uncertainties.Also,to reduce complexity,extreme and expected states are considered as interval modeling.Although this approach is effective,the fact that major wind farms are often located in remote locations and not accompanied by conventional units leads to conservative results.Furthermore,weights of extreme and expected states in the objective function are difficult to tune,resulting in significant differences between optimization and simulation costs.In this paper,each remote wind farm is paired with a conventional unit to dampen the effects of wind uncertainties without using expensive utility-scaled battery storage,and extra constraints are innovatively established to model pairing.Additionally,proper weights are derived through a novel quadratic fit of cost functions.The problem is solved by using a creative integration of our recent surrogate Lagrangian relaxation and branch-and-cut.Results demonstrate modeling accuracy,computational efficiency,and significant reduction of conservativeness of the previous approach.展开更多
In contrast to most existing works on robust unit commitment(UC),this study proposes a novel big-M-based mixed-integer linear programming(MILP)method to solve security-constrained UC problems considering the allowable...In contrast to most existing works on robust unit commitment(UC),this study proposes a novel big-M-based mixed-integer linear programming(MILP)method to solve security-constrained UC problems considering the allowable wind power output interval and its adjustable conservativeness.The wind power accommodation capability is usually limited by spinning reserve requirements and transmission line capacity in power systems with large-scale wind power integration.Therefore,by employing the big-M method and adding auxiliary 0-1 binary variables to describe the allowable wind power output interval,a bilinear programming problem meeting the security constraints of system operation is presented.Furthermore,an adjustable confidence level was introduced into the proposed robust optimization model to decrease the level of conservatism of the robust solutions.This can establish a trade-off between economy and security.To develop an MILP problem that can be solved by commercial solvers such as CPLEX,the big-M method is utilized again to represent the bilinear formulation as a series of linear inequality constraints and approximately address the nonlinear formulation caused by the adjustable conservativeness.Simulation studies on a modified IEEE 26-generator reliability test system connected to wind farms were performed to confirm the effectiveness and advantages of the proposed method.展开更多
In this paper, the robust H∞control problem for a class of stochastic systems with interval time-varying and distributed delays is discussed. The system under study involves parameter uncertainty, stochastic disturba...In this paper, the robust H∞control problem for a class of stochastic systems with interval time-varying and distributed delays is discussed. The system under study involves parameter uncertainty, stochastic disturbance, interval time-varying,and distributed delay. The aim is to design a delay-dependent robust H∞control which ensures the robust asymptotic stability of the given system and to express it in the form of linear matrix inequalities(LMIs). Numerical examples are given to demonstrate the effectiveness of the proposed method. The results are also compared with the existing results to show its conservativeness.展开更多
This paper considers H-infinity control problem for interval descriptor systems. Necessary and sufficient LMI-based conditions are derived for quadratic-like H-infinity control analysis of interval descriptor systems....This paper considers H-infinity control problem for interval descriptor systems. Necessary and sufficient LMI-based conditions are derived for quadratic-like H-infinity control analysis of interval descriptor systems. Using the analysis result, two types of feedback controllers are designed so that the closed-loop interval descriptor systems are admissible with H-infinity-norm less than a prescribed value. To the best of the authors's knowledge, this is the first paper to deal with the H-infinity control problem of interval descriptor systems in the literature.展开更多
Multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program(2014).T...Multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program(2014).The United States Preventive Services Task Force(USPSTF) October 2015 draft recommendation for CRC screening included mt-s DNA as an "alternative" screening test that "may be useful in select clinical circumstances",despite its very high sensitivity for early stage CRC.The evidence supporting mt-s DNA for routine screening use is robust.The clinical efficacy of mt-s DNA as measured by sensitivity,specificity,life-years gained(LYG),and CRC deaths averted is similar to or exceeds that of the other more specifically recommended screening options included in the draft document,especially those requiring annual testing adherence.In a population with primarily irregular screening participation,tests with the highest point sensitivity and reasonable specificity are more likely to favorably impact CRC related morbidity and mortality than those depending on annual adherence.This paper reviews the evidence supporting mt-s DNA for routine screening and demonstrates,using USPSTF's modeling data,that mt-s DNA at three-year intervals provides significant clinical net benefits and fewer complications per LYG than annual fecal immunochemical testing,high sensitivity guaiac based fecal occult blood testing and 10-year colonoscopy screening.展开更多
Stress-related mucosal disease is a typical complication of critically ill patients in the intensive care unit(ICU). It poses a risk of clinically relevant upper gastrointestinal(GI) bleeding. Therefore, stress ulcer ...Stress-related mucosal disease is a typical complication of critically ill patients in the intensive care unit(ICU). It poses a risk of clinically relevant upper gastrointestinal(GI) bleeding. Therefore, stress ulcer prophylaxis(SUP)is recommended in high-risk patients, especially those mechanically ventilated > 48 h and those with a manifest coagulopathy. Proton pump inhibitors(PPI) and, less effectively, histamine 2 receptor antagonists(H2RA) prevent GI bleeding in critically ill patients in the ICU. However, the routine use of pharmacological SUP does not reduce overall mortality in ICU patients. Moreover, recent studies revealed that SUP in the ICU might be associated with potential harm such as an increased risk of infectious complications, especially nosocomial pneumonia and Clostridium difficile-associated diarrhea. Additionally, special populations such as patients with liver cirrhosis may even have an increased mortality rate if treated with PPI. Likewise, PPI can be toxic for both the liver and the bone marrow, and some PPI show clinically relevant interactions with important other drugs like clopidogrel. Therefore, the agent of choice, the specific balance of risks and benefits for individual patients as well as the possible dose of PPI has to be chosen carefully. Alternatives to PPI prophylaxis include H2 RA and/or sucralfate. Instead of routine SUP, further trials should investigate risk-adjusted algorithms, balancing benefits and threats of SUP medication in the ICU.展开更多
During efficiency evaluating by DEA, the inputs and outputs of DMUs may be intervals because of insufficient information or measure error. For this reason, interval DEA is proposed. To make the efficiency scores more ...During efficiency evaluating by DEA, the inputs and outputs of DMUs may be intervals because of insufficient information or measure error. For this reason, interval DEA is proposed. To make the efficiency scores more discriminative, this paper builds an Interval Modified DEA (IMDEA) model based on MDEA. Furthermore, models of obtaining upper and lower bounds of the efficiency scores for each DMU are set up. Based on this, the DMUs are classified into three types. Next, a new order relation between intervals which can express the DM’s preference to the three types is proposed. As a result, a full and more convictive ranking is made on all the DMUs. Finally an example is given.展开更多
This paper shows that, for every unit interval graph, there is a labelling which is simultaneously optimal for the following seven graph labelling problems: bandwidth, cyclic bandwidth, profile, fill-in, cutwidth, mod...This paper shows that, for every unit interval graph, there is a labelling which is simultaneously optimal for the following seven graph labelling problems: bandwidth, cyclic bandwidth, profile, fill-in, cutwidth, modified cutwidth, and bandwidth sum(linear arrangement).展开更多
ONIOM quantum mechanics method is used in this paper to study one-carbon unit transfer from imidazolidine to 6-aminouracil derivates. The computation results show that this reaction can be completed via three paths ow...ONIOM quantum mechanics method is used in this paper to study one-carbon unit transfer from imidazolidine to 6-aminouracil derivates. The computation results show that this reaction can be completed via three paths owing to the three different proton transfer modes. By calculation and analysis, we can find the direct proton transfer is the preferable pathway.展开更多
基金supported in part by the Project Funded by ABB and U.S.National Science Foundation(ECCS-1509666)
文摘Grid integration of wind power is essential to reduce fossil fuel usage but challenging in view of the intermittent nature of wind.Recently,we developed a hybrid Markovian and interval approach for the unit commitment and economic dispatch problem where power generation of conventional units is linked to local wind states to dampen the effects of wind uncertainties.Also,to reduce complexity,extreme and expected states are considered as interval modeling.Although this approach is effective,the fact that major wind farms are often located in remote locations and not accompanied by conventional units leads to conservative results.Furthermore,weights of extreme and expected states in the objective function are difficult to tune,resulting in significant differences between optimization and simulation costs.In this paper,each remote wind farm is paired with a conventional unit to dampen the effects of wind uncertainties without using expensive utility-scaled battery storage,and extra constraints are innovatively established to model pairing.Additionally,proper weights are derived through a novel quadratic fit of cost functions.The problem is solved by using a creative integration of our recent surrogate Lagrangian relaxation and branch-and-cut.Results demonstrate modeling accuracy,computational efficiency,and significant reduction of conservativeness of the previous approach.
基金State Grid Jiangsu Electric Power Co.,Ltd(JF2020001)National Key Technology R&D Program of China(2017YFB0903300)State Grid Corporation of China(521OEF17001C).
文摘In contrast to most existing works on robust unit commitment(UC),this study proposes a novel big-M-based mixed-integer linear programming(MILP)method to solve security-constrained UC problems considering the allowable wind power output interval and its adjustable conservativeness.The wind power accommodation capability is usually limited by spinning reserve requirements and transmission line capacity in power systems with large-scale wind power integration.Therefore,by employing the big-M method and adding auxiliary 0-1 binary variables to describe the allowable wind power output interval,a bilinear programming problem meeting the security constraints of system operation is presented.Furthermore,an adjustable confidence level was introduced into the proposed robust optimization model to decrease the level of conservatism of the robust solutions.This can establish a trade-off between economy and security.To develop an MILP problem that can be solved by commercial solvers such as CPLEX,the big-M method is utilized again to represent the bilinear formulation as a series of linear inequality constraints and approximately address the nonlinear formulation caused by the adjustable conservativeness.Simulation studies on a modified IEEE 26-generator reliability test system connected to wind farms were performed to confirm the effectiveness and advantages of the proposed method.
基金Project supported by the Fund from the Department of Science and Technology(DST)(Grant No.SR/FTP/MS-039/2011)
文摘In this paper, the robust H∞control problem for a class of stochastic systems with interval time-varying and distributed delays is discussed. The system under study involves parameter uncertainty, stochastic disturbance, interval time-varying,and distributed delay. The aim is to design a delay-dependent robust H∞control which ensures the robust asymptotic stability of the given system and to express it in the form of linear matrix inequalities(LMIs). Numerical examples are given to demonstrate the effectiveness of the proposed method. The results are also compared with the existing results to show its conservativeness.
基金supported by the National Science Council of Taiwan (No.98-2221-E-151-049)
文摘This paper considers H-infinity control problem for interval descriptor systems. Necessary and sufficient LMI-based conditions are derived for quadratic-like H-infinity control analysis of interval descriptor systems. Using the analysis result, two types of feedback controllers are designed so that the closed-loop interval descriptor systems are admissible with H-infinity-norm less than a prescribed value. To the best of the authors's knowledge, this is the first paper to deal with the H-infinity control problem of interval descriptor systems in the literature.
文摘Multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program(2014).The United States Preventive Services Task Force(USPSTF) October 2015 draft recommendation for CRC screening included mt-s DNA as an "alternative" screening test that "may be useful in select clinical circumstances",despite its very high sensitivity for early stage CRC.The evidence supporting mt-s DNA for routine screening use is robust.The clinical efficacy of mt-s DNA as measured by sensitivity,specificity,life-years gained(LYG),and CRC deaths averted is similar to or exceeds that of the other more specifically recommended screening options included in the draft document,especially those requiring annual testing adherence.In a population with primarily irregular screening participation,tests with the highest point sensitivity and reasonable specificity are more likely to favorably impact CRC related morbidity and mortality than those depending on annual adherence.This paper reviews the evidence supporting mt-s DNA for routine screening and demonstrates,using USPSTF's modeling data,that mt-s DNA at three-year intervals provides significant clinical net benefits and fewer complications per LYG than annual fecal immunochemical testing,high sensitivity guaiac based fecal occult blood testing and 10-year colonoscopy screening.
基金The German Research Foundation,No.DFG Ta434/5-1the Interdisciplinary Center for Clinical Research(IZKF)Aachen
文摘Stress-related mucosal disease is a typical complication of critically ill patients in the intensive care unit(ICU). It poses a risk of clinically relevant upper gastrointestinal(GI) bleeding. Therefore, stress ulcer prophylaxis(SUP)is recommended in high-risk patients, especially those mechanically ventilated > 48 h and those with a manifest coagulopathy. Proton pump inhibitors(PPI) and, less effectively, histamine 2 receptor antagonists(H2RA) prevent GI bleeding in critically ill patients in the ICU. However, the routine use of pharmacological SUP does not reduce overall mortality in ICU patients. Moreover, recent studies revealed that SUP in the ICU might be associated with potential harm such as an increased risk of infectious complications, especially nosocomial pneumonia and Clostridium difficile-associated diarrhea. Additionally, special populations such as patients with liver cirrhosis may even have an increased mortality rate if treated with PPI. Likewise, PPI can be toxic for both the liver and the bone marrow, and some PPI show clinically relevant interactions with important other drugs like clopidogrel. Therefore, the agent of choice, the specific balance of risks and benefits for individual patients as well as the possible dose of PPI has to be chosen carefully. Alternatives to PPI prophylaxis include H2 RA and/or sucralfate. Instead of routine SUP, further trials should investigate risk-adjusted algorithms, balancing benefits and threats of SUP medication in the ICU.
文摘During efficiency evaluating by DEA, the inputs and outputs of DMUs may be intervals because of insufficient information or measure error. For this reason, interval DEA is proposed. To make the efficiency scores more discriminative, this paper builds an Interval Modified DEA (IMDEA) model based on MDEA. Furthermore, models of obtaining upper and lower bounds of the efficiency scores for each DMU are set up. Based on this, the DMUs are classified into three types. Next, a new order relation between intervals which can express the DM’s preference to the three types is proposed. As a result, a full and more convictive ranking is made on all the DMUs. Finally an example is given.
文摘This paper shows that, for every unit interval graph, there is a labelling which is simultaneously optimal for the following seven graph labelling problems: bandwidth, cyclic bandwidth, profile, fill-in, cutwidth, modified cutwidth, and bandwidth sum(linear arrangement).
文摘ONIOM quantum mechanics method is used in this paper to study one-carbon unit transfer from imidazolidine to 6-aminouracil derivates. The computation results show that this reaction can be completed via three paths owing to the three different proton transfer modes. By calculation and analysis, we can find the direct proton transfer is the preferable pathway.