This article gives a general model using specific periodic special functions, which is degenerate elliptic Weierstrass P functions whose presence in the governing equations through the forcing terms simplify the perio...This article gives a general model using specific periodic special functions, which is degenerate elliptic Weierstrass P functions whose presence in the governing equations through the forcing terms simplify the periodic Navier Stokes equations (PNS) at the centers of cells of the 3-Torus. Satisfying a divergence-free vector field and periodic boundary conditions respectively with a general spatio-temporal forcing term which is smooth and spatially periodic, the existence of solutions which have finite time singularities can occur starting with the first derivative and higher with respect to time. The existence of a subspace of the solution space where v<sub>3</sub> is continuous and {C, y<sub>1</sub>, y<sub>1</sub><sup>2</sup>}, is linearly independent in the additive argument of the solution in terms of the Lambert W function, (y<sub>1</sub><sup>2</sup>=y<sub>2</sub>, C∈R) together with the condition v<sub>2</sub>=-2y<sub>1</sub>v<sub>1</sub>. On this subspace, the Biot Savart Law holds exactly [see Section 2 (Equation (13))]. Also on this subspace, an expression X (part of PNS equations) vanishes which contains all the expressions in derivatives of v<sub>1</sub> and v<sub>2</sub> and the forcing terms in the plane which are related as with the cancellation of all such terms in governing PDE. The y<sub>3</sub> component forcing term is arbitrarily small in ε ball where Weierstrass P functions touch the center of the ball both for inviscid and viscous cases. As a result, a significant simplification occurs with a v<sub>3 </sub>only governing PDE resulting. With viscosity present as v changes from zero to the fully viscous case at v =1 the solution for v<sub>3</sub> reaches a peak in the third component y<sub>3</sub>. Consequently, there exists a dipole which is not centered at the center of the cell of the Lattice. Hence since the dipole by definition has an equal in magnitude positive and negative peak in y<sub>3</sub>, then the dipole Riemann cut-off surface is covered by a closed surface which is the sphere and where a given cell of dimensions [-1, 1]<sup>3</sup> is circumscribed on a sphere of radius 1. For such a closed surface containing a dipole it necessarily follows that the flux at the surface of the sphere of v<sub>3</sub> wrt to surface normal n is zero including at the points where the surface of sphere touches the cube walls. At the finite time singularity on the sphere a rotation boundary condition is deduced. It is shown that v<sub>3</sub> is spatially finite on the Riemann Sphere and the forcing is oscillatory in y<sub>3</sub> component if the velocity v3</sub> is. It is true that . A boundary condition on the sphere shows the rotation of a sphere of viscous fluid. Finally on the sphere a solution for v3</sub> is obtained which is proven to be Hölder continuous and it is shown that it is possible to extend Hölder continuity on the sphere uniquely to all of the interior of the ball.展开更多
This article gives a general model using specific periodic special functions, that is, degenerate elliptic Weierstrass P functions composed with the LambertW function, whose presence in the governing equations through...This article gives a general model using specific periodic special functions, that is, degenerate elliptic Weierstrass P functions composed with the LambertW function, whose presence in the governing equations through the forcing terms simplify the periodic Navier Stokes equations (PNS) at the centers of arbitrary r balls of the 3-Torus. The continuity equation is satisfied together with spatially periodic boundary conditions. The yicomponent forcing terms consist of a function F as part of its expression that is arbitrarily small in an r ball where it is associated with a singular forcing expression both for inviscid and viscous cases. As a result, a significant simplification occurs with a v3(vifor all velocity components) only governing PDE resulting. The extension of three restricted subspaces in each of the principal directions in the Cartesian plane is shown as the Cartesian product ℋ=Jx,t×Jy,t×Jz,t. On each of these subspaces vi,i=1,2,3is continuous and there exists a linear independent subspace associated with the argument of the W function. Here the 3-Torus is built up from each compact segment of length 2R on each of the axes on the 3 principal directions x, y, and z. The form of the scaled velocities for non zero scaled δis related to the definition of the W function such that e−W(ξ)=W(ξ)ξwhere ξdepends on t and proportional to δ→0for infinite time t. The ratio Wξis equal to 1, making the limit δ→0finite and well defined. Considering r balls where the function F=(x−ai)2+(y−bi)2+(z−ci)2−ηset equal to −1e+rwhere r>0. is such that the forcing is singular at every distance r of centres of cubes each containing an r-ball. At the centre of the balls, the forcing is infinite. The main idea is that a system of singular initial value problems with infinite forcing is to be solved for where the velocities are shown to be locally Hölder continuous. It is proven that the limit of these singular problems shifts the finite time blowup time ti∗for first and higher derivatives to t=∞thereby indicating that there is no finite time blowup. Results in the literature can provide a systematic approach to study both large space and time behaviour for singular solutions to the Navier Stokes equations. Among the references, it has been shown that mathematical tools can be applied to study the asymptotic properties of solutions.展开更多
In this paper, we introduce and study the notion of HB-closed sets in L-topological space. Then, HB-convergence theory for L-molecular nets and L-ideals is established in terms of HB-closedness. Finally, we give a new...In this paper, we introduce and study the notion of HB-closed sets in L-topological space. Then, HB-convergence theory for L-molecular nets and L-ideals is established in terms of HB-closedness. Finally, we give a new definition of fuzzy H-continuous [1] which is called HB-continuity on the basis of the notion of H-bounded L-subsets in L-topological space. Then we give characterizations and properties by making use of HB-converges theory of L-molecular nets and L-ideals.展开更多
In this paper,we investigate the strong Feller property of stochastic differential equations(SDEs)with super-linear drift and Hölder diffusion coefficients.By utilizing the Girsanov theorem,coupling method,trunca...In this paper,we investigate the strong Feller property of stochastic differential equations(SDEs)with super-linear drift and Hölder diffusion coefficients.By utilizing the Girsanov theorem,coupling method,truncation method and the Yamada-Watanabe approximation technique,we derived the strong Feller property of the solution.展开更多
1引言Hölder不等式是非常重要的不等式,本文首先给出Hölder不等式的一个等价形式,然后利用函数的凸性给出了Hölder不等式的一种新的证明方法,并据此结合受控理论(theory of majorization)给出Cauchy-Schwarz不等式的一...1引言Hölder不等式是非常重要的不等式,本文首先给出Hölder不等式的一个等价形式,然后利用函数的凸性给出了Hölder不等式的一种新的证明方法,并据此结合受控理论(theory of majorization)给出Cauchy-Schwarz不等式的一种加细及一个新的反向Hölder不等式.我们需要一些简单的符号和高等数学知识.展开更多
We obtain the H?lder continuity and joint H?lder continuity in space and time for the random field solution to the parabolic Anderson equation ■ in d-dimensional space, where ■ is a mean zero Gaussian noise with tem...We obtain the H?lder continuity and joint H?lder continuity in space and time for the random field solution to the parabolic Anderson equation ■ in d-dimensional space, where ■ is a mean zero Gaussian noise with temporal covariance γ0 and spatial covariance given by a spectral density μ(ξ). We assume that ■ and ■ , where αi, i = 1, · · ·, d(or α) can take negative value.展开更多
In order to find out changes in the main fertility indicators of continuous cropping tobacco fields in Henan Province with years of continuous cropping,5 typical tobacco fields( Jia County,Shaoling District,Fangcheng ...In order to find out changes in the main fertility indicators of continuous cropping tobacco fields in Henan Province with years of continuous cropping,5 typical tobacco fields( Jia County,Shaoling District,Fangcheng County,Xiangcheng County,and Song County) were studied. Indicators in question included activity of main enzymes( sucrase,urease,catalase,and acid phosphatase),p H value,organic matters,total nitrogen,available phosphorus and available potassium. The results indicate that in most tobacco fields,the activity of sucrase and urease increased in two years of continuous cropping,later,it showed a declining trend with increase in years of continuous cropping; in some fields,it directly declined with increase in years of continuous cropping; the activity of catalase increased in two years of continuous cropping,later,it showed a declining trend with increase in years of continuous cropping,and it became stable after three years of continuous cropping;generally,the activity of acid phosphatase declined with increase in the years of continuous cropping within 3 years continuous cropping,later,it became stable. Except Fangcheng County,the soil p H value of other districts( counties) generally declined with increase in years of continuous cropping,and it was in the range of 5. 6-6. 8. With the increase in continuous cropping,the soil organic matters( SOM) in tobacco fields of Jia County and Song County declined,changes of SOM in tobacco fields of Fangcheng County and Xiangcheng County were not obvious,and SOM showed the trend of first decline then rise in Shaoling District. In most tobacco fields( Jia County,Xiangcheng County,and Song County),the total nitrogen showed a declining trend; in Shaoling District,it showed a trend of first decline then rise; in Fangcheng County,it showed a rising trend. The available phosphorus firstly slightly declined then rose in tobacco fields of Shaoling District and Song County; it showed a trend of first rise then decline in Jia County; there were no obvious changes in Fangcheng County and Xiangcheng County. Changes in the available potassium were different in tobacco fields. In sum,there are certain rules for changes in soil enzyme activity and nutrient content in tobacco fields in Henan Province,but changes are not completely the same. It is concluded that the site conditions and farming activities exert a certain influence on soil enzyme activity,p H value,organic matters,and nitrogen,phosphorus and potassium content. Therefore,to solve obstacles in continuous cropping of tobacco fields,different regions should take different measures.展开更多
In this paper, we introduce a K Hölder p-adic derivative that can be applied to fractal curves with different Hölder exponent K. We will show that the Koch curve satisfies the Hölder conditi...In this paper, we introduce a K Hölder p-adic derivative that can be applied to fractal curves with different Hölder exponent K. We will show that the Koch curve satisfies the Hölder condition with exponent and has a 4-adic arithmetic-analytic representation. We will prove that the Koch curve has exact -Hölder 4-adic derivative.展开更多
BACKGROUND The effects of prostaglandin E(PGE)combined with continuous renal replacement therapy(CRRT)on renal function and inflammatory responses in patients with septic acute kidney injury(SAKI)remain unclear.AIM To...BACKGROUND The effects of prostaglandin E(PGE)combined with continuous renal replacement therapy(CRRT)on renal function and inflammatory responses in patients with septic acute kidney injury(SAKI)remain unclear.AIM To investigate the effects of PGE combined with CRRT on urinary augmenter of liver regeneration(ALR),urinary Na+/H+exchanger 3(NHE3),and serum inflammatory cytokines in patients with SAKI.METHODS The clinical data of 114 patients with SAKI admitted to Yichang Second People's Hospital from May 2017 to January 2019 were collected.Fifty-three cases treated by CRRT alone were included in a control group,while the other 61 cases treated with PGE combined with CRRT were included in an experimental group.Their urinary ALR,urinary NHE3,serum inflammatory cytokines,renal function indices,and immune function indices were detected.Changes in disease recovery and the incidence of adverse reactions were observed.The 28-d survival curve was plotted.RESULTS Before treatment,urinary ALR,urinary NHE3,blood urea nitrogen(BUN),serum creatinine(SCr),CD3+T lymphocytes,CD4+T lymphocytes,and CD4+/CD8+T lymphocyte ratio in the control and experimental groups were approximately the same.After treatment,urinary ALR and NHE3 decreased,while BUN,SCr,CD3+T lymphocytes,CD4+T lymphocytes,and CD4+/CD8+T lymphocyte ratio increased in all subjects.Urinary ALR,urinary NHE3,BUN,and SCr in the experimental group were significantly lower than those in the control group,while CD3+T lymphocytes,CD4+T lymphocytes,and CD4+/CD8+T lymphocyte ratio were significantly higher than those in the control group(P<0.05).After treatment,the levels of tumor necrosis factor-α,interleukin-18,and high sensitivity C-reactive protein in the experimental group were significantly lower than those in the control group(P<0.05).The time for urine volume recovery and intensive care unit treatment in the experimental group was significantly shorter than that in the control group(P<0.05),although there was no statistically significant difference in hospital stays between the two groups.The total incidence of adverse reactions did not differ statistically between the two groups.The 28-d survival rate in the experimental group(80.33%)was significantly higher than that in the control group(66.04%).CONCLUSION PGE combined with CRRT is clinically effective for treating SAKI,and the combination therapy can significantly improve renal function and reduce inflammatory responses.展开更多
Let n≥2 and let L be a second-order elliptic operator of divergence form with coefficients consisting of both an elliptic symmetric part and a BMO anti-symmetric part in ℝ^(n).In this article,we consider the weighted...Let n≥2 and let L be a second-order elliptic operator of divergence form with coefficients consisting of both an elliptic symmetric part and a BMO anti-symmetric part in ℝ^(n).In this article,we consider the weighted Kato square root problem for L.More precisely,we prove that the square root L^(1/2)satisfies the weighted L^(p)estimates||L^(1/2)(f)||L_(ω)^p(R^(n))≤C||■f||L_(ω)^p(R^(n);R^(n))for any p∈(1,∞)andω∈Ap(ℝ^(n))(the class of Muckenhoupt weights),and that||■f||L_(ω)^p(R^(n);R^(n))≤C||L^(1/2)(f)||L_(ω)^p(R^(n))for any p∈(1,2+ε)andω∈Ap(ℝ^(n))∩RH_(2+ε/p),(R^(n))(the class of reverse Hölder weights),whereε∈(0,∞)is a constant depending only on n and the operator L,and where(2+ε/p)'denotes the Hölder conjugate exponent of 2+ε/p.Moreover,for any given q∈(2,∞),we give a sufficient condition to obtain that||■f||L_(ω)^p(R^(n);R^(n))≤C||L^(1/2)(f)||L_(ω)^p(R^(n))for any p∈(1,q)andω∈A_(p)(R^(n))∩pRH_(q/p),(R^(n)).As an application,we prove that when the coefficient matrix A that appears in L satisfies the small BMO condition,the Riesz transform∇L^(−1/2)is bounded on L_(ω)^(p)(ℝ^(n))for any given p∈(1,∞)andω∈Ap(ℝ^(n)).Furthermore,applications to the weighted L^(2)-regularity problem with the Dirichlet or the Neumann boundary condition are also given.展开更多
The Hǒlder continuity is proved for the gradient of the solution Jo the one-sided obstacle problem of the following variational inequality in the case 1<p<2
In this paper we discuss the quasilinear parabolic equation U_■=▽(u^u(1-u)~β.Vu)+■(x,t.u)▽u+C(x,t,u) which is degenerate at u =0 and u=1.Let u(x,t)be a weak solution of the equation satisfying 0<u(x,t)<1.Un...In this paper we discuss the quasilinear parabolic equation U_■=▽(u^u(1-u)~β.Vu)+■(x,t.u)▽u+C(x,t,u) which is degenerate at u =0 and u=1.Let u(x,t)be a weak solution of the equation satisfying 0<u(x,t)<1.Under some assumptions we establish H■lder continuity of u(x,t).展开更多
The fast and high response detection of neurotoxic H_(2)S is of great importance for the environment.In this paper,directly electrospinning technology on the ceramic tube is developed to improve the response of H_(2)S...The fast and high response detection of neurotoxic H_(2)S is of great importance for the environment.In this paper,directly electrospinning technology on the ceramic tube is developed to improve the response of H_(2)S detector based on superlong SnO_(2)fibers.The submillimeter continuous fibers are deposited directly on ceramic tubes by in-situ electrospinning method and can keep morphology of fibers during calcination.By employing this technology,CuO-doped SnO_(2)fiber H_(2)S detectors are fabricated,and 10%atom CuO-doped SnO_(2)H_(2)S detector shows the highest response of 40 toward 1 ppm H_(2)S at 150℃while the response is only 3.6 for the H_(2)S detector prepared in traditional route.In addition,the in-situ electrospinning H_(2)S detectors show faster response and recovery compared to the H_(2)S detectors fabricated by the conventional way.The high and fast response of H_(2)S detectors based on in-situ electrospinning can be ascribed to the continuous fiber structure and CuO modification.The present in-situ electrospinning technology may provide a new strategy for the development of other gasdetectors and bio-detectors with fast and high response.展开更多
The Hoider continuity is proved to bounded solutions of degenerate elliptic e-quations involving measures. The structural conditions of the equation are more general and therestrictions on the structural coofficients ...The Hoider continuity is proved to bounded solutions of degenerate elliptic e-quations involving measures. The structural conditions of the equation are more general and therestrictions on the structural coofficients are weaker.展开更多
文摘This article gives a general model using specific periodic special functions, which is degenerate elliptic Weierstrass P functions whose presence in the governing equations through the forcing terms simplify the periodic Navier Stokes equations (PNS) at the centers of cells of the 3-Torus. Satisfying a divergence-free vector field and periodic boundary conditions respectively with a general spatio-temporal forcing term which is smooth and spatially periodic, the existence of solutions which have finite time singularities can occur starting with the first derivative and higher with respect to time. The existence of a subspace of the solution space where v<sub>3</sub> is continuous and {C, y<sub>1</sub>, y<sub>1</sub><sup>2</sup>}, is linearly independent in the additive argument of the solution in terms of the Lambert W function, (y<sub>1</sub><sup>2</sup>=y<sub>2</sub>, C∈R) together with the condition v<sub>2</sub>=-2y<sub>1</sub>v<sub>1</sub>. On this subspace, the Biot Savart Law holds exactly [see Section 2 (Equation (13))]. Also on this subspace, an expression X (part of PNS equations) vanishes which contains all the expressions in derivatives of v<sub>1</sub> and v<sub>2</sub> and the forcing terms in the plane which are related as with the cancellation of all such terms in governing PDE. The y<sub>3</sub> component forcing term is arbitrarily small in ε ball where Weierstrass P functions touch the center of the ball both for inviscid and viscous cases. As a result, a significant simplification occurs with a v<sub>3 </sub>only governing PDE resulting. With viscosity present as v changes from zero to the fully viscous case at v =1 the solution for v<sub>3</sub> reaches a peak in the third component y<sub>3</sub>. Consequently, there exists a dipole which is not centered at the center of the cell of the Lattice. Hence since the dipole by definition has an equal in magnitude positive and negative peak in y<sub>3</sub>, then the dipole Riemann cut-off surface is covered by a closed surface which is the sphere and where a given cell of dimensions [-1, 1]<sup>3</sup> is circumscribed on a sphere of radius 1. For such a closed surface containing a dipole it necessarily follows that the flux at the surface of the sphere of v<sub>3</sub> wrt to surface normal n is zero including at the points where the surface of sphere touches the cube walls. At the finite time singularity on the sphere a rotation boundary condition is deduced. It is shown that v<sub>3</sub> is spatially finite on the Riemann Sphere and the forcing is oscillatory in y<sub>3</sub> component if the velocity v3</sub> is. It is true that . A boundary condition on the sphere shows the rotation of a sphere of viscous fluid. Finally on the sphere a solution for v3</sub> is obtained which is proven to be Hölder continuous and it is shown that it is possible to extend Hölder continuity on the sphere uniquely to all of the interior of the ball.
文摘This article gives a general model using specific periodic special functions, that is, degenerate elliptic Weierstrass P functions composed with the LambertW function, whose presence in the governing equations through the forcing terms simplify the periodic Navier Stokes equations (PNS) at the centers of arbitrary r balls of the 3-Torus. The continuity equation is satisfied together with spatially periodic boundary conditions. The yicomponent forcing terms consist of a function F as part of its expression that is arbitrarily small in an r ball where it is associated with a singular forcing expression both for inviscid and viscous cases. As a result, a significant simplification occurs with a v3(vifor all velocity components) only governing PDE resulting. The extension of three restricted subspaces in each of the principal directions in the Cartesian plane is shown as the Cartesian product ℋ=Jx,t×Jy,t×Jz,t. On each of these subspaces vi,i=1,2,3is continuous and there exists a linear independent subspace associated with the argument of the W function. Here the 3-Torus is built up from each compact segment of length 2R on each of the axes on the 3 principal directions x, y, and z. The form of the scaled velocities for non zero scaled δis related to the definition of the W function such that e−W(ξ)=W(ξ)ξwhere ξdepends on t and proportional to δ→0for infinite time t. The ratio Wξis equal to 1, making the limit δ→0finite and well defined. Considering r balls where the function F=(x−ai)2+(y−bi)2+(z−ci)2−ηset equal to −1e+rwhere r>0. is such that the forcing is singular at every distance r of centres of cubes each containing an r-ball. At the centre of the balls, the forcing is infinite. The main idea is that a system of singular initial value problems with infinite forcing is to be solved for where the velocities are shown to be locally Hölder continuous. It is proven that the limit of these singular problems shifts the finite time blowup time ti∗for first and higher derivatives to t=∞thereby indicating that there is no finite time blowup. Results in the literature can provide a systematic approach to study both large space and time behaviour for singular solutions to the Navier Stokes equations. Among the references, it has been shown that mathematical tools can be applied to study the asymptotic properties of solutions.
文摘In this paper, we introduce and study the notion of HB-closed sets in L-topological space. Then, HB-convergence theory for L-molecular nets and L-ideals is established in terms of HB-closedness. Finally, we give a new definition of fuzzy H-continuous [1] which is called HB-continuity on the basis of the notion of H-bounded L-subsets in L-topological space. Then we give characterizations and properties by making use of HB-converges theory of L-molecular nets and L-ideals.
基金Supported by the National Natural Science Foundation of China(11926322)the Fundamental Research Funds for the Central Universities of South-Central MinZu University(CZY22013,3212023sycxjj001)。
文摘In this paper,we investigate the strong Feller property of stochastic differential equations(SDEs)with super-linear drift and Hölder diffusion coefficients.By utilizing the Girsanov theorem,coupling method,truncation method and the Yamada-Watanabe approximation technique,we derived the strong Feller property of the solution.
文摘1引言Hölder不等式是非常重要的不等式,本文首先给出Hölder不等式的一个等价形式,然后利用函数的凸性给出了Hölder不等式的一种新的证明方法,并据此结合受控理论(theory of majorization)给出Cauchy-Schwarz不等式的一种加细及一个新的反向Hölder不等式.我们需要一些简单的符号和高等数学知识.
基金supported by an NSERC granta startup fund of University of Albertasupported by Martin Hairer’s Leverhulme Trust leadership award
文摘We obtain the H?lder continuity and joint H?lder continuity in space and time for the random field solution to the parabolic Anderson equation ■ in d-dimensional space, where ■ is a mean zero Gaussian noise with temporal covariance γ0 and spatial covariance given by a spectral density μ(ξ). We assume that ■ and ■ , where αi, i = 1, · · ·, d(or α) can take negative value.
基金Supported by Key Scientific and Technological Plan Project of Henan Tobacco Company(HYKJM201304)
文摘In order to find out changes in the main fertility indicators of continuous cropping tobacco fields in Henan Province with years of continuous cropping,5 typical tobacco fields( Jia County,Shaoling District,Fangcheng County,Xiangcheng County,and Song County) were studied. Indicators in question included activity of main enzymes( sucrase,urease,catalase,and acid phosphatase),p H value,organic matters,total nitrogen,available phosphorus and available potassium. The results indicate that in most tobacco fields,the activity of sucrase and urease increased in two years of continuous cropping,later,it showed a declining trend with increase in years of continuous cropping; in some fields,it directly declined with increase in years of continuous cropping; the activity of catalase increased in two years of continuous cropping,later,it showed a declining trend with increase in years of continuous cropping,and it became stable after three years of continuous cropping;generally,the activity of acid phosphatase declined with increase in the years of continuous cropping within 3 years continuous cropping,later,it became stable. Except Fangcheng County,the soil p H value of other districts( counties) generally declined with increase in years of continuous cropping,and it was in the range of 5. 6-6. 8. With the increase in continuous cropping,the soil organic matters( SOM) in tobacco fields of Jia County and Song County declined,changes of SOM in tobacco fields of Fangcheng County and Xiangcheng County were not obvious,and SOM showed the trend of first decline then rise in Shaoling District. In most tobacco fields( Jia County,Xiangcheng County,and Song County),the total nitrogen showed a declining trend; in Shaoling District,it showed a trend of first decline then rise; in Fangcheng County,it showed a rising trend. The available phosphorus firstly slightly declined then rose in tobacco fields of Shaoling District and Song County; it showed a trend of first rise then decline in Jia County; there were no obvious changes in Fangcheng County and Xiangcheng County. Changes in the available potassium were different in tobacco fields. In sum,there are certain rules for changes in soil enzyme activity and nutrient content in tobacco fields in Henan Province,but changes are not completely the same. It is concluded that the site conditions and farming activities exert a certain influence on soil enzyme activity,p H value,organic matters,and nitrogen,phosphorus and potassium content. Therefore,to solve obstacles in continuous cropping of tobacco fields,different regions should take different measures.
文摘In this paper, we introduce a K Hölder p-adic derivative that can be applied to fractal curves with different Hölder exponent K. We will show that the Koch curve satisfies the Hölder condition with exponent and has a 4-adic arithmetic-analytic representation. We will prove that the Koch curve has exact -Hölder 4-adic derivative.
文摘BACKGROUND The effects of prostaglandin E(PGE)combined with continuous renal replacement therapy(CRRT)on renal function and inflammatory responses in patients with septic acute kidney injury(SAKI)remain unclear.AIM To investigate the effects of PGE combined with CRRT on urinary augmenter of liver regeneration(ALR),urinary Na+/H+exchanger 3(NHE3),and serum inflammatory cytokines in patients with SAKI.METHODS The clinical data of 114 patients with SAKI admitted to Yichang Second People's Hospital from May 2017 to January 2019 were collected.Fifty-three cases treated by CRRT alone were included in a control group,while the other 61 cases treated with PGE combined with CRRT were included in an experimental group.Their urinary ALR,urinary NHE3,serum inflammatory cytokines,renal function indices,and immune function indices were detected.Changes in disease recovery and the incidence of adverse reactions were observed.The 28-d survival curve was plotted.RESULTS Before treatment,urinary ALR,urinary NHE3,blood urea nitrogen(BUN),serum creatinine(SCr),CD3+T lymphocytes,CD4+T lymphocytes,and CD4+/CD8+T lymphocyte ratio in the control and experimental groups were approximately the same.After treatment,urinary ALR and NHE3 decreased,while BUN,SCr,CD3+T lymphocytes,CD4+T lymphocytes,and CD4+/CD8+T lymphocyte ratio increased in all subjects.Urinary ALR,urinary NHE3,BUN,and SCr in the experimental group were significantly lower than those in the control group,while CD3+T lymphocytes,CD4+T lymphocytes,and CD4+/CD8+T lymphocyte ratio were significantly higher than those in the control group(P<0.05).After treatment,the levels of tumor necrosis factor-α,interleukin-18,and high sensitivity C-reactive protein in the experimental group were significantly lower than those in the control group(P<0.05).The time for urine volume recovery and intensive care unit treatment in the experimental group was significantly shorter than that in the control group(P<0.05),although there was no statistically significant difference in hospital stays between the two groups.The total incidence of adverse reactions did not differ statistically between the two groups.The 28-d survival rate in the experimental group(80.33%)was significantly higher than that in the control group(66.04%).CONCLUSION PGE combined with CRRT is clinically effective for treating SAKI,and the combination therapy can significantly improve renal function and reduce inflammatory responses.
基金supported by the Key Project of Gansu Provincial National Science Foundation(23JRRA1022)the National Natural Science Foundation of China(12071431)+1 种基金the Fundamental Research Funds for the Central Universities(lzujbky-2021-ey18)the Innovative Groups of Basic Research in Gansu Province(22JR5RA391).
文摘Let n≥2 and let L be a second-order elliptic operator of divergence form with coefficients consisting of both an elliptic symmetric part and a BMO anti-symmetric part in ℝ^(n).In this article,we consider the weighted Kato square root problem for L.More precisely,we prove that the square root L^(1/2)satisfies the weighted L^(p)estimates||L^(1/2)(f)||L_(ω)^p(R^(n))≤C||■f||L_(ω)^p(R^(n);R^(n))for any p∈(1,∞)andω∈Ap(ℝ^(n))(the class of Muckenhoupt weights),and that||■f||L_(ω)^p(R^(n);R^(n))≤C||L^(1/2)(f)||L_(ω)^p(R^(n))for any p∈(1,2+ε)andω∈Ap(ℝ^(n))∩RH_(2+ε/p),(R^(n))(the class of reverse Hölder weights),whereε∈(0,∞)is a constant depending only on n and the operator L,and where(2+ε/p)'denotes the Hölder conjugate exponent of 2+ε/p.Moreover,for any given q∈(2,∞),we give a sufficient condition to obtain that||■f||L_(ω)^p(R^(n);R^(n))≤C||L^(1/2)(f)||L_(ω)^p(R^(n))for any p∈(1,q)andω∈A_(p)(R^(n))∩pRH_(q/p),(R^(n)).As an application,we prove that when the coefficient matrix A that appears in L satisfies the small BMO condition,the Riesz transform∇L^(−1/2)is bounded on L_(ω)^(p)(ℝ^(n))for any given p∈(1,∞)andω∈Ap(ℝ^(n)).Furthermore,applications to the weighted L^(2)-regularity problem with the Dirichlet or the Neumann boundary condition are also given.
基金in part by Zhongshan University Science Research Fund
文摘The Hǒlder continuity is proved for the gradient of the solution Jo the one-sided obstacle problem of the following variational inequality in the case 1<p<2
文摘In this paper we discuss the quasilinear parabolic equation U_■=▽(u^u(1-u)~β.Vu)+■(x,t.u)▽u+C(x,t,u) which is degenerate at u =0 and u=1.Let u(x,t)be a weak solution of the equation satisfying 0<u(x,t)<1.Under some assumptions we establish H■lder continuity of u(x,t).
基金supported by National Natural Science Foundation of China(51772082,51804106,51572078,51772086 and 51872087)。
文摘The fast and high response detection of neurotoxic H_(2)S is of great importance for the environment.In this paper,directly electrospinning technology on the ceramic tube is developed to improve the response of H_(2)S detector based on superlong SnO_(2)fibers.The submillimeter continuous fibers are deposited directly on ceramic tubes by in-situ electrospinning method and can keep morphology of fibers during calcination.By employing this technology,CuO-doped SnO_(2)fiber H_(2)S detectors are fabricated,and 10%atom CuO-doped SnO_(2)H_(2)S detector shows the highest response of 40 toward 1 ppm H_(2)S at 150℃while the response is only 3.6 for the H_(2)S detector prepared in traditional route.In addition,the in-situ electrospinning H_(2)S detectors show faster response and recovery compared to the H_(2)S detectors fabricated by the conventional way.The high and fast response of H_(2)S detectors based on in-situ electrospinning can be ascribed to the continuous fiber structure and CuO modification.The present in-situ electrospinning technology may provide a new strategy for the development of other gasdetectors and bio-detectors with fast and high response.
文摘The Hoider continuity is proved to bounded solutions of degenerate elliptic e-quations involving measures. The structural conditions of the equation are more general and therestrictions on the structural coofficients are weaker.