As the brand-new national tourism image,"Nihao!China"was unveiled around the world,more and more foreign tourists will embark on a journey to explore the natural beauty,rich history and cultivate lasting fri...As the brand-new national tourism image,"Nihao!China"was unveiled around the world,more and more foreign tourists will embark on a journey to explore the natural beauty,rich history and cultivate lasting friendships in China.展开更多
The successful holding of"Nihao!China"--2024 China Ice&Snow Tourism Overseas Promotion Season has not only deepened the understanding of the people of various countries on the ice&snow cultural and t...The successful holding of"Nihao!China"--2024 China Ice&Snow Tourism Overseas Promotion Season has not only deepened the understanding of the people of various countries on the ice&snow cultural and tourist resources with Chinese characteristics,enhanced the exchanges and cooperation between Chinese and foreign cultural and tourist industries,but also accumulated rich experience for the brand construction of the series of event"Themed Tourism Overseas Promotion Season".展开更多
From the Netherlands Holiday Travel Expo to the MadridTEInternational Tourism Exhibition,"Nihao! China" the Chinanational tourism image has been appearing frequently on theinternational stage recently, conve...From the Netherlands Holiday Travel Expo to the MadridTEInternational Tourism Exhibition,"Nihao! China" the Chinanational tourism image has been appearing frequently on theinternational stage recently, conveying the beauty of Easternculture and sending out China's invitation.展开更多
With the development of language,the range of adjective phrases that can be placed in“hao(好)+AP”and affirmative construction“hao(好)+bu(不)+AP”in modern Chinese is continuously expanding.This paper proves through...With the development of language,the range of adjective phrases that can be placed in“hao(好)+AP”and affirmative construction“hao(好)+bu(不)+AP”in modern Chinese is continuously expanding.This paper proves through investigation on network language and spoken language that an increasing number of adjectives can be placed in“hao(好)+AP”and affirmative construction“hao(好)+bu(不)+AP”,and there is a growing acceptance of“hao(好)+AP”.This paper attributes this phenomenon to the following reasons.Firstly,Chinese southern dialects have a growing influence on modern spoken Chinese,leading to an increased acceptance of“hao(好)+AP”and negative construction“hao(好)+bu(不)+AP”.Secondly,whether the“hao(好)+bu(不)+AP”construction is affirmative or negative largely depends on the context.In a fixed context,there is a higher acceptance of AP in the affirmative and negative“hao(好)+bu(不)+AP”constructions.Thirdly,influenced by the Principle of Least Effort in spoken language,the speakers and receivers of spoken dialogues tend to believe“what they hear is what they get”.As a result,the“hao(好)+AP”is used more frequently in expressing affirmative meanings.展开更多
AIM To evaluate the therapeutic mechanism of Yinchenhao Chengqi (YCHCQ) decoction (containing mainly Herba Artemisia capillaris) combined with endoscopic sphincterotomy (EST) for endotoxemia (ETM) in acute cholangitis...AIM To evaluate the therapeutic mechanism of Yinchenhao Chengqi (YCHCQ) decoction (containing mainly Herba Artemisia capillaris) combined with endoscopic sphincterotomy (EST) for endotoxemia (ETM) in acute cholangitis.METHODS Twenty-one cases of acute cholangitis with ETM were divided randomly into two groups: group A, 10 patients treated with YCHCQ decoction combined with EST, group B, 11 patients treated with EST. The incidence rate of ETM, plasmic ET, serum superoxide dismutase (SOD) activity, malonyldialdehyde (MDA), complement C3 and C-reactive protein (CRP) were studied respectively.RESULTS The ET level of group A (35.92ng/L±8.30ng/L) was significantly reduced after 7 days of treatment (P<0.05) in contrast to that of group B (47.8ng/L±11.62ng/L), so did the level of MDA and CRP. But the SOD activity and C3 level in group A increased significantly (P<0.05).CONCLUSION YCHCQ decoction combined with EST had a beneficial effect for ETM in acute cholangitis.INTRODUCTIONEndotoxemia (ETM) is one of the most important physiopathologic causes of acute cholangitis and it is the trigger of cytokines and inflammatory factors. In recent studies it has been found that Yinchenhao Chengqi (YCHCQ) decoction has a beneficial effect on ETM in acute cholangitis. With the development of endoscopic surgery, endoscopic sphincterotomy (EST) has become an effective replacement for some operations in the treatment of acute cholangitis[1]. The effect of YCHCQ decoction combined with EST on ET, oxygen free radical and complement C3 was observed in order to find out its therapeutic mechanism.展开更多
AIM: To evaluate human pancreatic carcinoma cell line(PANC-1) cells apoptosis and Bcl-2 and Bax expression induced by Yin Chen Hao Decoction(YCHD).METHODS: The cell growth inhibitory rate was determined by MTT assay. ...AIM: To evaluate human pancreatic carcinoma cell line(PANC-1) cells apoptosis and Bcl-2 and Bax expression induced by Yin Chen Hao Decoction(YCHD).METHODS: The cell growth inhibitory rate was determined by MTT assay. Apoptosis of PANC-1 cells before and after treatment with YCHD was determined by TUNEL staining. Expression of the apoptosisassociated genes, Bcl-2 and Bax, was detected by immunohistochemical staining and reverse transcription-PCR.RESULTS: YCHD inhibited the growth of PANC-1 cells. Following treatment with YCHD for 24-96 h, the apoptotic rate of PANC-1 cells increased with time. In addition, the positive rate of Bcl-2 protein expression decreased in a time-dependent manner, whereas the positive rate of Bax protein expression increased in a time-dependent manner. Following treatment of with YCHD for 24-96 h, expression of BAX m RNA increased gradually and BCL-2 m RNA reduced gradually with time.CONCLUSION: YCHD induces apoptosis of PANC-1 cells mediated in part via up-regulation of BAX and down-regulation of BCL-2.展开更多
A sliding mode control approach is proposed to implement the synchronization of the chain tree network. The doublescroll circuit chaos systems are treated as nodes and the network is constructed with the state variabl...A sliding mode control approach is proposed to implement the synchronization of the chain tree network. The doublescroll circuit chaos systems are treated as nodes and the network is constructed with the state variable coupling. By selecting a switching sliding surface, the chaos synchronization of the network is achieved with one control input only. The stability analysis and the numerical simulations demonstrate that the complete synchronization in a chain network can be realized for all nodes.展开更多
In order to investigate the effect of dwarfing inter stock on the structure of pear trees,investigations were made to the tree and group structure of the 4-year-old spindle-shaped‘Huangguan'pear grafted with vigo...In order to investigate the effect of dwarfing inter stock on the structure of pear trees,investigations were made to the tree and group structure of the 4-year-old spindle-shaped‘Huangguan'pear grafted with vigorous stock( Pyrus betulaefolia stock) and that grafted with the dwarfing inter stock‘Zhong ai 1 hao'( P. betulaefolia rootstock). The results showed that the 4-year-old‘Huangguan'pear trees grafted with the dwarfing inter stock‘ Zhong ai 1 hao'were 2. 87 m high on average,with 70. 70% of short braches,converted into 21 016. 0 branches per 667 m^2,840. 64 m^2 of leaf area per 667 m^2 with the leaf area coefficient of 1. 75.On the other hand,for the‘Huangguan'trees grafted with vigorous stocks,the average tree height was 3. 17 m,and the short branch proportion was 63. 20%,converted into 15 806. 4 branches per 667 m^2,719. 28 m^2 of leaf area per 667 m^2 with the leaf area coefficient of 1. 55. Therefore,the use of dwarfing inter stock‘Zhong ai 1 hao'had significant dwarfing effect on‘Huangguan'pear trees,which also showed significant yield increasing effect.展开更多
"Sheng Qing Yi Hao",a new fruit radish F1 hybrid,which was bred from HSR54 A,a self-bred sterile line,and HS1356,an excellent male parent.The flesh of the roots is emerald green,delicate,sweet and crisp.The ..."Sheng Qing Yi Hao",a new fruit radish F1 hybrid,which was bred from HSR54 A,a self-bred sterile line,and HS1356,an excellent male parent.The flesh of the roots is emerald green,delicate,sweet and crisp.The skin of the roots is little spicy.It takes about 70 d from sowing to maturity.The fleshy roots have a length of 22-27 cm,a diameter of 6-8 cm,and a root weight of 0.8-1.1 kg.The F1 hybrid has stronger resistance to soft rot disease in the field the control group‘Chengyangqing’.It is suitable for cultivation in greenhouse in spring and open field in autumn in north China.展开更多
It’s hard to imagine the unlimitedness of human life until you see it with your own eyes.Professor Chaohui Ye demonstrates to us how unlimited and meaningful a life can be,by maximizing his talents and efforts in eve...It’s hard to imagine the unlimitedness of human life until you see it with your own eyes.Professor Chaohui Ye demonstrates to us how unlimited and meaningful a life can be,by maximizing his talents and efforts in every position.He is such a gentleman,a great scientist,an encouraging supervisor,an insightful research group leader and a profound thinker,who inspired and influenced so many,including the authors and guest editors of this special issue.展开更多
EDITOR’S NOTE: We were shocked to learn that the well-known Tibetologist Huang Hao had passed away in May 18, 2004. As he told his family not to hold any funeral ceremony, many of his friends would not have the chanc...EDITOR’S NOTE: We were shocked to learn that the well-known Tibetologist Huang Hao had passed away in May 18, 2004. As he told his family not to hold any funeral ceremony, many of his friends would not have the chance to express their feelings and see him for the last time... Here Dr. Zhang Yun expresses the feeling of the entire Tibetan studies circle. The mourning expressed by him is also the expression of us all.展开更多
The understanding of Hao’liao’ge is very important for the understanding of Hong’lou’meng so Hao’liao’ge can be said to be the key point of the whole novel.Therefore,it is necessary to pay attention to the compa...The understanding of Hao’liao’ge is very important for the understanding of Hong’lou’meng so Hao’liao’ge can be said to be the key point of the whole novel.Therefore,it is necessary to pay attention to the comparative study of English translation of Hao’liao’ge in the English translation studies of Hong’lou’meng.Nida's Functional Equivalence Theory will be used to com⁃pare and analyze the two translations of Hao’liao’ge and explore the different translation strategies of the two translators,hoping to have some inspiration for poetry translation and give Chinese and English readers a deeper understanding of Hao’liao’ge.展开更多
Objective:Qu Du Qiang Fei 1 Hao Fang(QDQF1)is a novel Chinese herbal medicine formula used to treat coronavirus disease 2019(COVID-19).However,the pharmacological mechanisms of action of QDQF1 remain unclear.The objec...Objective:Qu Du Qiang Fei 1 Hao Fang(QDQF1)is a novel Chinese herbal medicine formula used to treat coronavirus disease 2019(COVID-19).However,the pharmacological mechanisms of action of QDQF1 remain unclear.The objective of this study was to identify the effective ingredients and biological targets of QDQF1 for COVID-19 treatment.Materials and Methods:The effective ingredients and mechanisms of action of QDQF1 were analyzed by using network pharmacology methods,which included an analysis of the effective ingredients and corresponding targets,COVID-19-related target acquisition,compound-target network analyses,protein-protein interaction network analysis,Kyoto Encyclopedia of Genes and Genomes(KEGG)and Gene Ontology(GO)enrichment analyses,and molecular docking studies.Results:In total,288 effective QDQF1 ingredients were identified.We identified 51 core targets from the 148 targets through an overlap between putative QDQF1 targets and COVID-19-related targets.Six key components,including formononetin,kaempferol,luteolin,naringenin,quercetin,and wogonin were identified through component-target network analyses.GO functional enrichment analysis of the core targets revealed 1296 items,while KEGG pathway enrichment analysis identified 148 signaling pathways.Nine central targets(CCL2,CXCL8,IL1B,IL6,MAPK1,MAPK3,MAPK8,STAT3,and TNF)related to the COVID-19 pathway were identified in the KEGG pathway enrichment analysis.Furthermore,molecular docking analysis suggested that the docking scores of the six key components to the nine central targets were better than those to remdesivir.Conclusions:QDQF1 may regulate multiple immune-and inflammation-related targets to inhibit the progression of severe acute respiratory syndrome coronavirus 2,and thus,may be suitable for the treatment of COVID-19.展开更多
The Shaolin Temple is China’s renowned temple and a hub for the Chan Sect of Buddhism,more widely known in the West by its Japanesename,Zen Buddhism.Located at the foot of the Songshan Mountain in central China’s He...The Shaolin Temple is China’s renowned temple and a hub for the Chan Sect of Buddhism,more widely known in the West by its Japanesename,Zen Buddhism.Located at the foot of the Songshan Mountain in central China’s Henan Province,the Shaolin Temple is famous for Zen Buddhism and Shaolin Kungfu.Learning Chinese Kungfu at the Shaolin Temple is conside red one of the top 10 things to do in China.展开更多
文摘As the brand-new national tourism image,"Nihao!China"was unveiled around the world,more and more foreign tourists will embark on a journey to explore the natural beauty,rich history and cultivate lasting friendships in China.
文摘The successful holding of"Nihao!China"--2024 China Ice&Snow Tourism Overseas Promotion Season has not only deepened the understanding of the people of various countries on the ice&snow cultural and tourist resources with Chinese characteristics,enhanced the exchanges and cooperation between Chinese and foreign cultural and tourist industries,but also accumulated rich experience for the brand construction of the series of event"Themed Tourism Overseas Promotion Season".
文摘From the Netherlands Holiday Travel Expo to the MadridTEInternational Tourism Exhibition,"Nihao! China" the Chinanational tourism image has been appearing frequently on theinternational stage recently, conveying the beauty of Easternculture and sending out China's invitation.
文摘With the development of language,the range of adjective phrases that can be placed in“hao(好)+AP”and affirmative construction“hao(好)+bu(不)+AP”in modern Chinese is continuously expanding.This paper proves through investigation on network language and spoken language that an increasing number of adjectives can be placed in“hao(好)+AP”and affirmative construction“hao(好)+bu(不)+AP”,and there is a growing acceptance of“hao(好)+AP”.This paper attributes this phenomenon to the following reasons.Firstly,Chinese southern dialects have a growing influence on modern spoken Chinese,leading to an increased acceptance of“hao(好)+AP”and negative construction“hao(好)+bu(不)+AP”.Secondly,whether the“hao(好)+bu(不)+AP”construction is affirmative or negative largely depends on the context.In a fixed context,there is a higher acceptance of AP in the affirmative and negative“hao(好)+bu(不)+AP”constructions.Thirdly,influenced by the Principle of Least Effort in spoken language,the speakers and receivers of spoken dialogues tend to believe“what they hear is what they get”.As a result,the“hao(好)+AP”is used more frequently in expressing affirmative meanings.
文摘AIM To evaluate the therapeutic mechanism of Yinchenhao Chengqi (YCHCQ) decoction (containing mainly Herba Artemisia capillaris) combined with endoscopic sphincterotomy (EST) for endotoxemia (ETM) in acute cholangitis.METHODS Twenty-one cases of acute cholangitis with ETM were divided randomly into two groups: group A, 10 patients treated with YCHCQ decoction combined with EST, group B, 11 patients treated with EST. The incidence rate of ETM, plasmic ET, serum superoxide dismutase (SOD) activity, malonyldialdehyde (MDA), complement C3 and C-reactive protein (CRP) were studied respectively.RESULTS The ET level of group A (35.92ng/L±8.30ng/L) was significantly reduced after 7 days of treatment (P<0.05) in contrast to that of group B (47.8ng/L±11.62ng/L), so did the level of MDA and CRP. But the SOD activity and C3 level in group A increased significantly (P<0.05).CONCLUSION YCHCQ decoction combined with EST had a beneficial effect for ETM in acute cholangitis.INTRODUCTIONEndotoxemia (ETM) is one of the most important physiopathologic causes of acute cholangitis and it is the trigger of cytokines and inflammatory factors. In recent studies it has been found that Yinchenhao Chengqi (YCHCQ) decoction has a beneficial effect on ETM in acute cholangitis. With the development of endoscopic surgery, endoscopic sphincterotomy (EST) has become an effective replacement for some operations in the treatment of acute cholangitis[1]. The effect of YCHCQ decoction combined with EST on ET, oxygen free radical and complement C3 was observed in order to find out its therapeutic mechanism.
基金Supported by Traditional Chinese Medicine Administration of Zhejiang Province,China,No.2014ZA068
文摘AIM: To evaluate human pancreatic carcinoma cell line(PANC-1) cells apoptosis and Bcl-2 and Bax expression induced by Yin Chen Hao Decoction(YCHD).METHODS: The cell growth inhibitory rate was determined by MTT assay. Apoptosis of PANC-1 cells before and after treatment with YCHD was determined by TUNEL staining. Expression of the apoptosisassociated genes, Bcl-2 and Bax, was detected by immunohistochemical staining and reverse transcription-PCR.RESULTS: YCHD inhibited the growth of PANC-1 cells. Following treatment with YCHD for 24-96 h, the apoptotic rate of PANC-1 cells increased with time. In addition, the positive rate of Bcl-2 protein expression decreased in a time-dependent manner, whereas the positive rate of Bax protein expression increased in a time-dependent manner. Following treatment of with YCHD for 24-96 h, expression of BAX m RNA increased gradually and BCL-2 m RNA reduced gradually with time.CONCLUSION: YCHD induces apoptosis of PANC-1 cells mediated in part via up-regulation of BAX and down-regulation of BCL-2.
基金Project supported by the State Key Program of the National Natural Science Foundation of China(Grant No.11232009)the Shanghai Leading Academic Discipline Project,China(Grant No.S30106)
文摘A sliding mode control approach is proposed to implement the synchronization of the chain tree network. The doublescroll circuit chaos systems are treated as nodes and the network is constructed with the state variable coupling. By selecting a switching sliding surface, the chaos synchronization of the network is achieved with one control input only. The stability analysis and the numerical simulations demonstrate that the complete synchronization in a chain network can be realized for all nodes.
基金Supported by the China Agriculture Research System(Pear)(CARS-28-36)the National Natural Science Foundation of China(31601708)+4 种基金the Agricultural Stock Breeding Project of Shandong Province(2016LZGC034)the Youth Foundation of Shandong Academy of Agricultural Sciences(2015YQN40)the National Science and Technology Plan for Rural Areas of China(2014BAD16B03-4)the Project for Agricultural Science and Technology Innovation of Shandong Academy of Agricultural Sciences(CXGC2018F03)the Key Science and Technology Innovation Project of Shandong Province(2018CXGC0208)
文摘In order to investigate the effect of dwarfing inter stock on the structure of pear trees,investigations were made to the tree and group structure of the 4-year-old spindle-shaped‘Huangguan'pear grafted with vigorous stock( Pyrus betulaefolia stock) and that grafted with the dwarfing inter stock‘Zhong ai 1 hao'( P. betulaefolia rootstock). The results showed that the 4-year-old‘Huangguan'pear trees grafted with the dwarfing inter stock‘ Zhong ai 1 hao'were 2. 87 m high on average,with 70. 70% of short braches,converted into 21 016. 0 branches per 667 m^2,840. 64 m^2 of leaf area per 667 m^2 with the leaf area coefficient of 1. 75.On the other hand,for the‘Huangguan'trees grafted with vigorous stocks,the average tree height was 3. 17 m,and the short branch proportion was 63. 20%,converted into 15 806. 4 branches per 667 m^2,719. 28 m^2 of leaf area per 667 m^2 with the leaf area coefficient of 1. 55. Therefore,the use of dwarfing inter stock‘Zhong ai 1 hao'had significant dwarfing effect on‘Huangguan'pear trees,which also showed significant yield increasing effect.
文摘"Sheng Qing Yi Hao",a new fruit radish F1 hybrid,which was bred from HSR54 A,a self-bred sterile line,and HS1356,an excellent male parent.The flesh of the roots is emerald green,delicate,sweet and crisp.The skin of the roots is little spicy.It takes about 70 d from sowing to maturity.The fleshy roots have a length of 22-27 cm,a diameter of 6-8 cm,and a root weight of 0.8-1.1 kg.The F1 hybrid has stronger resistance to soft rot disease in the field the control group‘Chengyangqing’.It is suitable for cultivation in greenhouse in spring and open field in autumn in north China.
文摘It’s hard to imagine the unlimitedness of human life until you see it with your own eyes.Professor Chaohui Ye demonstrates to us how unlimited and meaningful a life can be,by maximizing his talents and efforts in every position.He is such a gentleman,a great scientist,an encouraging supervisor,an insightful research group leader and a profound thinker,who inspired and influenced so many,including the authors and guest editors of this special issue.
文摘EDITOR’S NOTE: We were shocked to learn that the well-known Tibetologist Huang Hao had passed away in May 18, 2004. As he told his family not to hold any funeral ceremony, many of his friends would not have the chance to express their feelings and see him for the last time... Here Dr. Zhang Yun expresses the feeling of the entire Tibetan studies circle. The mourning expressed by him is also the expression of us all.
文摘The understanding of Hao’liao’ge is very important for the understanding of Hong’lou’meng so Hao’liao’ge can be said to be the key point of the whole novel.Therefore,it is necessary to pay attention to the comparative study of English translation of Hao’liao’ge in the English translation studies of Hong’lou’meng.Nida's Functional Equivalence Theory will be used to com⁃pare and analyze the two translations of Hao’liao’ge and explore the different translation strategies of the two translators,hoping to have some inspiration for poetry translation and give Chinese and English readers a deeper understanding of Hao’liao’ge.
基金funded by the National Natural Science Foundation of China(81973543)the Shanghai Sailing Program(No.22YF1449800),China。
文摘Objective:Qu Du Qiang Fei 1 Hao Fang(QDQF1)is a novel Chinese herbal medicine formula used to treat coronavirus disease 2019(COVID-19).However,the pharmacological mechanisms of action of QDQF1 remain unclear.The objective of this study was to identify the effective ingredients and biological targets of QDQF1 for COVID-19 treatment.Materials and Methods:The effective ingredients and mechanisms of action of QDQF1 were analyzed by using network pharmacology methods,which included an analysis of the effective ingredients and corresponding targets,COVID-19-related target acquisition,compound-target network analyses,protein-protein interaction network analysis,Kyoto Encyclopedia of Genes and Genomes(KEGG)and Gene Ontology(GO)enrichment analyses,and molecular docking studies.Results:In total,288 effective QDQF1 ingredients were identified.We identified 51 core targets from the 148 targets through an overlap between putative QDQF1 targets and COVID-19-related targets.Six key components,including formononetin,kaempferol,luteolin,naringenin,quercetin,and wogonin were identified through component-target network analyses.GO functional enrichment analysis of the core targets revealed 1296 items,while KEGG pathway enrichment analysis identified 148 signaling pathways.Nine central targets(CCL2,CXCL8,IL1B,IL6,MAPK1,MAPK3,MAPK8,STAT3,and TNF)related to the COVID-19 pathway were identified in the KEGG pathway enrichment analysis.Furthermore,molecular docking analysis suggested that the docking scores of the six key components to the nine central targets were better than those to remdesivir.Conclusions:QDQF1 may regulate multiple immune-and inflammation-related targets to inhibit the progression of severe acute respiratory syndrome coronavirus 2,and thus,may be suitable for the treatment of COVID-19.
文摘The Shaolin Temple is China’s renowned temple and a hub for the Chan Sect of Buddhism,more widely known in the West by its Japanesename,Zen Buddhism.Located at the foot of the Songshan Mountain in central China’s Henan Province,the Shaolin Temple is famous for Zen Buddhism and Shaolin Kungfu.Learning Chinese Kungfu at the Shaolin Temple is conside red one of the top 10 things to do in China.