Objective: To observe the blocking effect of Huoxiang Zhengqi liqu id (HXZQL) on histamine release of basophils. Methods: The study was conducted using HXZQL to neutralize and b lock IgE and antagonize the effect of I...Objective: To observe the blocking effect of Huoxiang Zhengqi liqu id (HXZQL) on histamine release of basophils. Methods: The study was conducted using HXZQL to neutralize and b lock IgE and antagonize the effect of IL 3 induced enhancing histamine relea se of bosaphils. Concentration and percentage of histamine release of bosaphils were tested by the basophil histamine release test. Results: The HXZQL drug serum had obvious inhibitive effect on degranulation of bosaphils induced by IgE antigen antibody complex ( P <0.0 5) and can successfully weaken the histamine release of basophils stimulated by IL 3. When compared with those in the untreated group, it showed P <0.01. Conclusion: HXZQL drug serum may neutralize and block IgE and has inhibitive effects on degranulation of cells when resensitized by antigens. It can also block allergic response type Ⅰ by antagonizing the effect of IL 3 induced enhancing histamine release.展开更多
1. Objectives of Study and Back-groundFacing expansion and development de-mands, the Beijing Municipal City Plan-ning Commission (BMCPC) devised a plan to conserve the townscape of tra-ditional courtyard houses in the...1. Objectives of Study and Back-groundFacing expansion and development de-mands, the Beijing Municipal City Plan-ning Commission (BMCPC) devised a plan to conserve the townscape of tra-ditional courtyard houses in the historic center of Beijing, and 25 districts展开更多
As part of Cambria Sinophone World Series,headed by Victor Mair(University of Permsylvania),Chinese Avant-Garde Fiction:Quest for Historicity and Transcendent Truth examines works by Su Tong,Yu Hua and Ge Fei,three ke...As part of Cambria Sinophone World Series,headed by Victor Mair(University of Permsylvania),Chinese Avant-Garde Fiction:Quest for Historicity and Transcendent Truth examines works by Su Tong,Yu Hua and Ge Fei,three key writers in a significant trend that emerged in the Chinese literary world around 1985,flourished in the late 1980s and early 1990s before it faded away after the mid-1990s.展开更多
目的:针对药物流行病学在临床药学中的研究领域开展可视化引文分析。方法:借助可视化引文分析工具Hist Cite,以Web of Science核心合集的科学引文索引数据库扩展版为数据源,综合运用文献计量分析、引文分析和可视化技术,分析药物流行病...目的:针对药物流行病学在临床药学中的研究领域开展可视化引文分析。方法:借助可视化引文分析工具Hist Cite,以Web of Science核心合集的科学引文索引数据库扩展版为数据源,综合运用文献计量分析、引文分析和可视化技术,分析药物流行病学在临床药学研究文献中的核心期刊和当前研究的热点,并用可视化方法展示临床药学研究的发展历史。结果:得到了Pharmacoepidemiology and Drug Safety等10种药物流行病学在临床药学领域的核心期刊,确定了药物流行病学研究的热门研究主题,并用引文编年图直观地展示药物流行病学在临床药学研究领域的发展历史和阶段。结论:药物流行病学在临床药学研究领域发展迅速,Hist Cite能够快速、直观地展现药物流行病学在临床药学研究领域的发展轨迹。展开更多
以中国矿业大学图书馆开展的ESI学科评估工作实践为例,阐述基于ESI和InCites数据库,用进入全球1%的学科、学者、高被引论文、热点论文等指标,对中国矿业大学的学科建设现状进行宏观分析,从文献分析的角度得出其学科发展现状,评价学科的...以中国矿业大学图书馆开展的ESI学科评估工作实践为例,阐述基于ESI和InCites数据库,用进入全球1%的学科、学者、高被引论文、热点论文等指标,对中国矿业大学的学科建设现状进行宏观分析,从文献分析的角度得出其学科发展现状,评价学科的优势与不足。首先是针对无法深入研究众多文献间的关联问题,建议将Histcite、Citespace以及Web of Science平台自带的引文分析工具作为ESI学科评估工具的辅助工具结合使用,以达到更深入全面的对学科建设进行分析,进而为高校的学科发展政策的制定提供可靠的依据,更为后期学科建设与发展提供参考,其次是对参与学科评估工作人员能力的要求,建议从加强培训方面给出相应的对策,并在提高学科评估工作人员能力的同时,根据各高校学科发展的情况与教师之间建立关系,为其日常的科学研究提供与学科相关的服务;最后是对以理工科为主的高校在学科建设发展中存在的弱势学科在文献资源缺乏的问题上提出应对措施。展开更多
基金The item is subsidized by Natural Science Fund of Fujian Province (No. C96044)
文摘Objective: To observe the blocking effect of Huoxiang Zhengqi liqu id (HXZQL) on histamine release of basophils. Methods: The study was conducted using HXZQL to neutralize and b lock IgE and antagonize the effect of IL 3 induced enhancing histamine relea se of bosaphils. Concentration and percentage of histamine release of bosaphils were tested by the basophil histamine release test. Results: The HXZQL drug serum had obvious inhibitive effect on degranulation of bosaphils induced by IgE antigen antibody complex ( P <0.0 5) and can successfully weaken the histamine release of basophils stimulated by IL 3. When compared with those in the untreated group, it showed P <0.01. Conclusion: HXZQL drug serum may neutralize and block IgE and has inhibitive effects on degranulation of cells when resensitized by antigens. It can also block allergic response type Ⅰ by antagonizing the effect of IL 3 induced enhancing histamine release.
基金supported by a Grant-in-Aid from Japan Society for the Promotion of Sciences as a Scientific Research (B) "Comparative Study of Conservation Method of Neighborhoods in Historic Cities in Japan and China" (Chair:Masaki Fujikawa)
文摘1. Objectives of Study and Back-groundFacing expansion and development de-mands, the Beijing Municipal City Plan-ning Commission (BMCPC) devised a plan to conserve the townscape of tra-ditional courtyard houses in the historic center of Beijing, and 25 districts
文摘As part of Cambria Sinophone World Series,headed by Victor Mair(University of Permsylvania),Chinese Avant-Garde Fiction:Quest for Historicity and Transcendent Truth examines works by Su Tong,Yu Hua and Ge Fei,three key writers in a significant trend that emerged in the Chinese literary world around 1985,flourished in the late 1980s and early 1990s before it faded away after the mid-1990s.
文摘目的:针对药物流行病学在临床药学中的研究领域开展可视化引文分析。方法:借助可视化引文分析工具Hist Cite,以Web of Science核心合集的科学引文索引数据库扩展版为数据源,综合运用文献计量分析、引文分析和可视化技术,分析药物流行病学在临床药学研究文献中的核心期刊和当前研究的热点,并用可视化方法展示临床药学研究的发展历史。结果:得到了Pharmacoepidemiology and Drug Safety等10种药物流行病学在临床药学领域的核心期刊,确定了药物流行病学研究的热门研究主题,并用引文编年图直观地展示药物流行病学在临床药学研究领域的发展历史和阶段。结论:药物流行病学在临床药学研究领域发展迅速,Hist Cite能够快速、直观地展现药物流行病学在临床药学研究领域的发展轨迹。
文摘以中国矿业大学图书馆开展的ESI学科评估工作实践为例,阐述基于ESI和InCites数据库,用进入全球1%的学科、学者、高被引论文、热点论文等指标,对中国矿业大学的学科建设现状进行宏观分析,从文献分析的角度得出其学科发展现状,评价学科的优势与不足。首先是针对无法深入研究众多文献间的关联问题,建议将Histcite、Citespace以及Web of Science平台自带的引文分析工具作为ESI学科评估工具的辅助工具结合使用,以达到更深入全面的对学科建设进行分析,进而为高校的学科发展政策的制定提供可靠的依据,更为后期学科建设与发展提供参考,其次是对参与学科评估工作人员能力的要求,建议从加强培训方面给出相应的对策,并在提高学科评估工作人员能力的同时,根据各高校学科发展的情况与教师之间建立关系,为其日常的科学研究提供与学科相关的服务;最后是对以理工科为主的高校在学科建设发展中存在的弱势学科在文献资源缺乏的问题上提出应对措施。
