The deprivation, importation, situational, and administrative control models have been used to explain inmate violence. More recently, HIV risk behaviors of inmates have been explained with the deprivation and importa...The deprivation, importation, situational, and administrative control models have been used to explain inmate violence. More recently, HIV risk behaviors of inmates have been explained with the deprivation and importation models. The goal of this study is to assess the utility of these models in describing inmate HIV risk behaviors and to identify additional models that may exist. Forty seven ex-offenders released from prison within three months of the study were recruited from a community based organization. They participated in focus group discussions that explored the contexts surrounding inmate engagement in HIV risk behaviors in prison. Data were analyzed using NVivo 7 and results were organized into themes. Inmates engaged in sex in exchange for money and for affection. Inmates who were drug users before incarceration were more likely to abuse drugs in prison. Security measures, if effective, deterred the entrance of illegal substance into prison, but when security is lax, inmates take the opportunity to engage in sex, and illegal substances are brought into prison. Our results reveal that deprivation, importation, situational, and administrative control factors are associated with HIV risk behaviors among inmates and they can be used in explaining these behaviors. The association of risk behaviors with long or life sentences suggests that fatalism may play a role in risk behaviors among inmates. Fatalism is a factor which requires future examination.展开更多
Introduction: Highly active antiretroviral tritherapies have improved the quality of life of people living with HIV (PVVIH) and extended their life expectancy. However, the nervous system is faced with a neurotropic v...Introduction: Highly active antiretroviral tritherapies have improved the quality of life of people living with HIV (PVVIH) and extended their life expectancy. However, the nervous system is faced with a neurotropic virus that evolves chronically, sometimes creating neurological disorders directly or indirectly linked to stigmatization or therapeutic effects. Objective: to determine the prevalence of depression associated with suicidal risk (SR) and identify associated factors. Patients and method: This was a prospective descriptive and analytical study from January 1 to November 30, 2022, including all HIV-positive patients receiving or not receiving antiretroviral therapy. The study took place in the infectious diseases department of Brazzaville University Hospital. This department has an inpatient capacity of 36 beds, and an outpatient capacity of 25 patients per day, three times a week. This is the largest center for PVVIH in Brazzaville. The Patient Heath Questionnaire 9 (PHQ-9) was used to assess the degree of depression and suicidal risk. Therapeutic adherence was assessed using the Morisky questionnaire. Data were analyzed using SPSS version 23 software. Qualitative variables were expressed as numbers and percentages, and quantitative variables as means and standard deviations. Statistical tests were used according to their applicability criteria. For all tests, the significance threshold was set at 0.05. Results: A total of 150 patients were consulted, constituting the sample size. The prevalence of depression and suicidal risk was 32%. These patients had an average age of 42.83 ± 10.24 years, were female (n = 101;67.3%), Christian (n = 97;64%), single (n = 68;45.3%). Stigmatization (n = 75;50%) was the reason for attempted suicide. HIV was perceived as treatable (n = 103;68.7%), unlucky (n = 62;41.3%). Patients were WHO stage 1 (n = 105;70%). RS was present in 47 cases (31.3%). Factors associated with depression and suicidal risk were age (p = 0.000), residence (p = 0.028), suicide attempt (p = 0.000), desire to procreate (p = 0.000) and ARV (antiretrovirals) side effects (p Conclusion: The prevalence of depression and suicidal risk was high, in line with stigma and socio-economic conditions. The associated factors were in line with those identified in the literature. Mental health needs to be integrated into the overall care of people living with HIV.展开更多
Background: The burden of COVID-19 and human immunodeficiency virus (HIV) are some of the major and persistent global health challenges of the twenty-first century. HIV and COVID-19 are expected to overlap in high HIV...Background: The burden of COVID-19 and human immunodeficiency virus (HIV) are some of the major and persistent global health challenges of the twenty-first century. HIV and COVID-19 are expected to overlap in high HIV-burden countries, posing several public health challenges as a result. Prisons are overcrowded, have limited space for social distancing and have inadequate ventilation systems, making it difficult to contain the spread of COVID-19 in addition to the high-risk behaviours of inmates which contribute to the spread of HIV within these facilities. This study aimed to determine the prevalence of COVID-19 among inmates in a prison facility with a relatively high HIV burden in Port Harcourt, Nigeria;investigating potential risk factors and co-infection with HIV. Methodology: The study employed a descriptive cross-sectional study design sampling 200 inmates from the Port Harcourt Maximum Security Custodial Centre from July to December 2022. A well-structured questionnaire was administered via interviews in addition to screening for HIV-1/2 antibodies as well as COVID-19 antigens using rapid diagnostic test kits. Descriptive statistics and chi-square were carried out on the GraphPad Prism 9 software with statistical significance defined as a p-value of less than 0.05 at a 95% confidence interval. Result: The prevalence of HIV from the current study was 6.5%, COVID-19 prevalence was reported to be 12.5% while HIV/COVID-19 co-infection was 1.5% The duration of incarceration, face mask use, frequent visitations and vaccination against COVID-19 were found to be significantly associated with the prevalence of COVID-19 in the studied population (p Conclusion: The current study reports a relatively high prevalence of HIV and COVID-19 among the inmates in the study area. It becomes expedient for the administrators of the correctional facility to properly screen new inmates for COVID-19, quarantine and manage cases, as well as provide them with personal protective equipment such as face masks. In-person visitation should be balanced with measures to prevent the spread of the infection, and mass vaccination campaigns should be promoted. Improving access to HIV screening and therapy for all prisoners should be prioritised to identify and manage the incidence of HIV early, reducing the risk of transmission, mitigating comorbidities and improving health outcomes.展开更多
我是一名医生。最近在一些国内网站上读到一些鼓励oral sex的文章,文章鼓吹,只要将性器官洗净,口交也很卫生。7月5日晨我在Yahoo!上读到此文,医生的职业道德促使我把此文投稿给贵刊。文章的第一句就提醒我们:the risk of contracting HI...我是一名医生。最近在一些国内网站上读到一些鼓励oral sex的文章,文章鼓吹,只要将性器官洗净,口交也很卫生。7月5日晨我在Yahoo!上读到此文,医生的职业道德促使我把此文投稿给贵刊。文章的第一句就提醒我们:the risk of contracting HIV from oral sex is higher than many people think.展开更多
China is currently experiencing one of the most rapidly expanding HIV epidemics in the world. Although the overall prevalence rate is still low, with a population of 1.3 billion, high-risk factors which have contribut...China is currently experiencing one of the most rapidly expanding HIV epidemics in the world. Although the overall prevalence rate is still low, with a population of 1.3 billion, high-risk factors which have contributed to the HIV/AIDS epidemics worldwide continue to prevail in China, including a high rate of injecting drug use and needle sharing, commercial sex with low rates of condom use, and concurrent sex with both commercial sex workers and noncom- mercial casual or steady sex partners. In addition, there are increasing “double risk” populations overlapping drug users and sex workers, as well as increasing rates of STDs and HIV among high-risk populations. Sexual transmission, therefore, may serve as a bridge connecting high-risk populations with general populations. There is an urgent need to prevent the spread of HIV from these high-risk populations into the general population of China.展开更多
A cross-sectional study using the snowball sampling method was conducted in May 2008 to investigate human immunodeficiency virus (HIV) infection status and related high risk factors among men who have sex with men ...A cross-sectional study using the snowball sampling method was conducted in May 2008 to investigate human immunodeficiency virus (HIV) infection status and related high risk factors among men who have sex with men (MSM) in Suzhou city of Jiangsu province. The researchers carried out a face-to-face questionnaire interview among MSM, and collected their blood samples to test for HIV and other sexually transmitted diseases (STDs). Among the 280 respondents, 91.1% had homosexual acts in the past 6 months and 87.5% had multiple homosex- ual partners; 46.4% had heterosexual sex in the past 6 months and 33.1% had multiple heterosexual partners. The rate of continued condom use was 44.3% in homosexual sex in the past 6 months, while the rate in heterosexual sex was 33.9%. Laboratory test results showed that the prevalences of HIV and syphilis were 7.1% (20/280) and 15.0% (42/280), respectively, but no HCV-positive person was found. In the multivariate logistic regression model, subjects with a monthly income of more than RMB $ 1,000 (OR=4.83,95% CI=1.44-16.22), subjects who often went to bars for sexual partners (OR=2.25, 95%CI=1.21-4.20), and subjects who had more than one sexual partner in the past 6 months (OR=0.49, 95%CI=0.25-0.97) and had sex with fixed sexual partners in the past 6 months (OR=0.42, 95%CI=0.25-0.75) were significantly associated with the rate of continued condom use in homosexual sex in the past 6 months. Unprotected sex and multiple sexual partners were more common among MSM in Suzhou city; furthermore, the prevalences of HIV infection and syphilis were relatively high. HIV preventive measures should be designed to address these risk factors and control the spread of HIV among MSM.展开更多
In Cameroon, despite extensive control efforts against HIV/AIDS, the number of new HIV infections is still on the rise. The factors contributing to this are not clearly understood. We hypothesized that it may lie on p...In Cameroon, despite extensive control efforts against HIV/AIDS, the number of new HIV infections is still on the rise. The factors contributing to this are not clearly understood. We hypothesized that it may lie on people living with HIV (PLHIV). In a case-control descriptive study, we studied the characteristics and sexual risky behaviour of PLHIV in the North West Region of Cameroon which has the highest HIV prevalence. Participants were screened for HIV and a structured questionnaire was used in data collection. An equivalent number (350) of PLHIV and controls who did not differ with respect to age and sex participated. Relative to the control, PLHIV were generally less educated (P < 0.001), poorer and less privileged (P < 0.001) with no stable source of income. Among participants that were once married, a greater proportion of PLHIV were divorced (OR = 5.23, P = 0.007), and widows (OR = 2.73, P = 0.001). Among participants that were single, a relatively greater proportion of PLHIV practiced multi-partner sex (OR = 4.55, P< 0.001). History of STDs was higher in PLHIV than the control (OR = 1.88, P = 0.001). Out of 350 PLHIV, 280 (80%) admitted to having had sexual intercourse after being diagnosed of which only 127 (41.78%) admitted to using condoms and 132 (47.14%) admitted to concealing their HIV status from their sexual partner(s). These findings have implications in HIV control programs which should target the poor and the less educated, as well as the sexual behaviour of PLHIV, so as to reverse the current rising trend of new infections in the country.展开更多
The aim of this study was to determine the incidence rates of HIV1/2 antibodies, HBV and HCV antibodies among voluntary blood donors and to estimate the residual risk of HIV, HBV and HCV infection among blood donors i...The aim of this study was to determine the incidence rates of HIV1/2 antibodies, HBV and HCV antibodies among voluntary blood donors and to estimate the residual risk of HIV, HBV and HCV infection among blood donors in Bukavu. We conducted a follow-up cohort study of volunteer blood donors who have made at least two blood donations in Bukavu (DRC) between January 2010 and December 2012. We recorded 2986 volunteer blood donors during the study period. The residual risk of viral transmission associated with the serological window was considered as equals to the incidence rate multiplied by the duration of the serological window period divided by 365. Seroprevalence in volunteer blood donors in Bukavu was 1.1% for HIV 1/2 antibodies, 4.0% for HBs Ag and 2.1% for hepatitis C antibody. The number of conversion between two blood donations (incident cases) were observed is 8, 12 and 37 donors respectively for HIV 1/2, HCV and hepatitis B between 2010 and 2012. Incidence rates reported for 1000 person-years were 11.0 for HIV, 51.7 for HBV and 17.1 for HCV. The residual risk as estimated from the window was 0.6 per 1000 donations or 1/1.515 donations for HIV, 3.1 per 1000 donations or 1/329 for HCV and 7.9 per 1000 donations or 1/126 donations for hepatitis B. The residual risk is high. The screening tests are not enough to ensure safe blood. The reduction of residual risk would be achieved through the effectiveness of preventive measures taken for transfusion chain, before and after the biological qualification of blood donation.展开更多
Objective To assess the HIV/STDs knowledge and risk behaviors related factors among female sex workers(FSWs)in Shanghai,China.Methods A cross-sectional study was conducted in 5 districts(including 3 suburbs and 2 urba...Objective To assess the HIV/STDs knowledge and risk behaviors related factors among female sex workers(FSWs)in Shanghai,China.Methods A cross-sectional study was conducted in 5 districts(including 3 suburbs and 2 urban districts).A total of 324 FSWs from 88 massage parlors and hair-beauty salons participated in the survey.An interviewer-administrated questionnaire was used to collect information.Results The average score of HIV/STDs knowledge was 15.2±3.9.Multivariate analyses indicated that limited education [odds ratio(OR):8.6,95% confidence interval(CI):2.9-25.6],coming from suburbs [odds ratio(OR):3.7,95% confidence interval(CI):2.0-6.8],monthly income less than 1500 RMB(220 US$)[odds ratio(OR):3.9,95% confidence interval(CI):1.9-8.1],without HIV/STDs-related education experience(OR:5.2,95% CI:2.8-9.5),and coming from provinces of low epidemic(OR:2.7,95% CI:1.1-6.6)were significant predictors of lower HIV/STDs knowledge.And 29.5% FSWs had sex without a condom when clients paid much more money,and 46.3% had the experience of condom broke or slipped during commercial sexual intercourse.Conclusion Health promotion should be conducted to enhance HIV/STDs knowledge and reduce risk behaviors among FSWs from suburbs with limited education in Shanghai especially.展开更多
Background: Although much concern has been expressed about the occupational risk posed to surgeons by the HIV pandemic infection, the paediatric age group is often seen as less likely to harbor the disease. Aim: To de...Background: Although much concern has been expressed about the occupational risk posed to surgeons by the HIV pandemic infection, the paediatric age group is often seen as less likely to harbor the disease. Aim: To determine the HIV infection rate among children presenting for surgical operations at the Lagos University Teaching Hospital (LUTH), Lagos. Materials, patients and method: Blood was taken from 1000 consecutive children referred to LUTH for surgical conditions and tested for HIV sero-positivity using the Western blot method. Consenting parents of sero-positive patients were also tested. Result: Five children tested positive for HIV, giving an overall infection rate of 0.5%. Four mothers and three consenting fathers were also positive. In one child, none of the parents was positive and he was suspected to have developed the disease from a previous blood transfusion prior to presentation in LUTH. This possibly resulted from transfusion of infected blood during its window period. Conclusion: Although the HIV infection rate of 0.5% in paediatric surgical group in Lagos is low, surgeons should vigilantly apply universal precautions to prevent needle-stick injuries while the rate of HIV infection should be periodically monitored to determine the trend.展开更多
Diagnosis of sexually transmitted infections is very important considering the spread of HIV and the extensive use of highly active antiretroviral therapy worldwide. This will assist in planning of treatment schedule ...Diagnosis of sexually transmitted infections is very important considering the spread of HIV and the extensive use of highly active antiretroviral therapy worldwide. This will assist in planning of treatment schedule in controlling these infections. The study therefore aimed at determining the prevalence of syphilis in HIV positive antiretroviral therapy naive patients in Cape Coast and the associated risk factors involved in infection. A cross-sectional study was carried out using initial HIV rapid and confirmation tests, and then Venereal Disease Research Laboratory test with the Ultra Rapid Test Kits for syphilis. Demographic data, risky sexual behaviours capable of co-transmission of both HIV and Syphilis, were also collected through the use of questionnaires. In all, 150 HIV positive antiretroviral naive subjects were studied and 15 (10%) were positive for VDRL test, with females (6.00%) and males (4.00%), who were mainly within the age group of 20 - 39 years. A significant number of males (p = 0.019) and females (p = 0.015) participants were not smoking with a fewer number of the females (p = 0.002) having multiple sexual partners. Also a smaller number of those who were infected with the bacteria (p = 0.004) did not support the control of sexually transmitted infection (p = 0.022). The result showed that co-infection of Syphilis in HIV positive antiretroviral therapy naive patients persists in the Cape Coast Metropolis, which is an indication of prominence of STIs that require further study on a larger scale to ascertain the extent of co-infection and to formulate policy for treatment to help minimize the rate of infection.展开更多
目的评估长沙地区2014年1月1日—2022年12月31日无偿献血者输血传播人类免疫缺陷病毒(h uma n immunodeficiency virus,HIV)残余风险。方法通过血站信息管理系统回顾性分析长沙血液中心2014年1月1日—2022年12月31日无偿献血者HIV血液...目的评估长沙地区2014年1月1日—2022年12月31日无偿献血者输血传播人类免疫缺陷病毒(h uma n immunodeficiency virus,HIV)残余风险。方法通过血站信息管理系统回顾性分析长沙血液中心2014年1月1日—2022年12月31日无偿献血者HIV血液筛查结果与疾病预防控制中心(CDC)反馈的确证结果,采用发病率-窗口期数学模型评估无偿献血者HIV筛查残余风险。结果研究期间长沙地区HIV确证阳性率为0.1995‰(273/1368333),其中初次献血者757455例,占比55.36%,确证阳性率0.2495‰(189/757455),重复献血者有610878例,占比44.64%,确证阳性率0.1375‰(84/610878),初次及重复献血者两组确证阳性率存在统计学差异(χ^(2)=21.270,P<0.001)。初次献血者HIV残余风险为1/204081.63高于重复献血者残余风险1/370370.37。如果只开展HIV血清学检测,窗口期参残余风险为1/85470,而增加HIV核酸检测血液筛查后,残余风险降低至1/250000,NAT筛查较血清学筛查能降低65.81%的残余风险。结论长沙地区无偿献血者输血传播HIV残余风险的评估有助于评价不同检测策略对血液安全的影响,保障血液质量。展开更多
Objective: It is in order to estimate the prevalence and incidence of HIV, the frequency of sexual risk behaviors, and perceptions of available resources to prevent and treat HIV among crack users in the San Salvador ...Objective: It is in order to estimate the prevalence and incidence of HIV, the frequency of sexual risk behaviors, and perceptions of available resources to prevent and treat HIV among crack users in the San Salvador Metropolitan Area. Methods: We conducted a survey of 420 crack users by using respondent-driven sampling to measure demographic characteristics, the quantity and frequency of drug use, history of STIs, including HIV, and experiences with organizations which provide prevention and treatment of HIV. Each participant offered a free and voluntary HIV test and was asked permission to share the results of the test with the study. Bernoullian modeling was used to estimate the prevalence and incidence of HIV among heterosexual males in this population. Results: The estimated prevalence was 7% (95% CI: 2.3% -9.8%) among participants who agreed to take the test and share the results, and 4.9% (95% CI: 2.8% -7.8%) assuming that those who did not take the test or share results were seronegative. Participants reported a high frequency of sexual risk behaviors. In addition, participants were reported to have little knowledge of organizations to prevent or treat HIV/AIDS;58% had never taken an HIV test prior to survey administration. Conclusions: Crack users in San Salvador are at high risk for HIV acquisition. HIV prevention interventions are urgently needed, especially interventions increasing access to HIV testing and prevention.展开更多
According to current guidelines, exposing mucous membrane to blood and body fluids of HIV infected people is risk of transmission. About 30% - 80% of HIV infected people have at least one oral manifestation. The most ...According to current guidelines, exposing mucous membrane to blood and body fluids of HIV infected people is risk of transmission. About 30% - 80% of HIV infected people have at least one oral manifestation. The most frequently occurring oral manifestations (pseudomembranous candidiasis, linear gingival erythema, etc.) give rise to bleeding either spontaneously or after stimulation, and strenuous stirring during oral sex and deep-mouth kissing increase risk of bleeding from oral manifestations, exposing oral and genital mucous membrane of partners to the blood. However, current guidelines assert that there’s little to no risk of getting HIV from oral sex and deep-mouth kissing. These guidelines are conflict with each other, suggesting potential problems with current prevention strategies which are based on the guidelines. After discussing existing data on animals, lesbians, young peoples, and occupational exposures, this paper suggests oral sex and deep-mouth kissing are risk factors when one partner has HIV-associated oral bleeding manifestations, and the number of infections associated with oral sex and deep-mouth kissing is significant. Current guidelines on HIV risk factors should be reevaluated urgently, and new studies should be undertaken with an open mind to explore risk factors.展开更多
文摘The deprivation, importation, situational, and administrative control models have been used to explain inmate violence. More recently, HIV risk behaviors of inmates have been explained with the deprivation and importation models. The goal of this study is to assess the utility of these models in describing inmate HIV risk behaviors and to identify additional models that may exist. Forty seven ex-offenders released from prison within three months of the study were recruited from a community based organization. They participated in focus group discussions that explored the contexts surrounding inmate engagement in HIV risk behaviors in prison. Data were analyzed using NVivo 7 and results were organized into themes. Inmates engaged in sex in exchange for money and for affection. Inmates who were drug users before incarceration were more likely to abuse drugs in prison. Security measures, if effective, deterred the entrance of illegal substance into prison, but when security is lax, inmates take the opportunity to engage in sex, and illegal substances are brought into prison. Our results reveal that deprivation, importation, situational, and administrative control factors are associated with HIV risk behaviors among inmates and they can be used in explaining these behaviors. The association of risk behaviors with long or life sentences suggests that fatalism may play a role in risk behaviors among inmates. Fatalism is a factor which requires future examination.
文摘Introduction: Highly active antiretroviral tritherapies have improved the quality of life of people living with HIV (PVVIH) and extended their life expectancy. However, the nervous system is faced with a neurotropic virus that evolves chronically, sometimes creating neurological disorders directly or indirectly linked to stigmatization or therapeutic effects. Objective: to determine the prevalence of depression associated with suicidal risk (SR) and identify associated factors. Patients and method: This was a prospective descriptive and analytical study from January 1 to November 30, 2022, including all HIV-positive patients receiving or not receiving antiretroviral therapy. The study took place in the infectious diseases department of Brazzaville University Hospital. This department has an inpatient capacity of 36 beds, and an outpatient capacity of 25 patients per day, three times a week. This is the largest center for PVVIH in Brazzaville. The Patient Heath Questionnaire 9 (PHQ-9) was used to assess the degree of depression and suicidal risk. Therapeutic adherence was assessed using the Morisky questionnaire. Data were analyzed using SPSS version 23 software. Qualitative variables were expressed as numbers and percentages, and quantitative variables as means and standard deviations. Statistical tests were used according to their applicability criteria. For all tests, the significance threshold was set at 0.05. Results: A total of 150 patients were consulted, constituting the sample size. The prevalence of depression and suicidal risk was 32%. These patients had an average age of 42.83 ± 10.24 years, were female (n = 101;67.3%), Christian (n = 97;64%), single (n = 68;45.3%). Stigmatization (n = 75;50%) was the reason for attempted suicide. HIV was perceived as treatable (n = 103;68.7%), unlucky (n = 62;41.3%). Patients were WHO stage 1 (n = 105;70%). RS was present in 47 cases (31.3%). Factors associated with depression and suicidal risk were age (p = 0.000), residence (p = 0.028), suicide attempt (p = 0.000), desire to procreate (p = 0.000) and ARV (antiretrovirals) side effects (p Conclusion: The prevalence of depression and suicidal risk was high, in line with stigma and socio-economic conditions. The associated factors were in line with those identified in the literature. Mental health needs to be integrated into the overall care of people living with HIV.
文摘Background: The burden of COVID-19 and human immunodeficiency virus (HIV) are some of the major and persistent global health challenges of the twenty-first century. HIV and COVID-19 are expected to overlap in high HIV-burden countries, posing several public health challenges as a result. Prisons are overcrowded, have limited space for social distancing and have inadequate ventilation systems, making it difficult to contain the spread of COVID-19 in addition to the high-risk behaviours of inmates which contribute to the spread of HIV within these facilities. This study aimed to determine the prevalence of COVID-19 among inmates in a prison facility with a relatively high HIV burden in Port Harcourt, Nigeria;investigating potential risk factors and co-infection with HIV. Methodology: The study employed a descriptive cross-sectional study design sampling 200 inmates from the Port Harcourt Maximum Security Custodial Centre from July to December 2022. A well-structured questionnaire was administered via interviews in addition to screening for HIV-1/2 antibodies as well as COVID-19 antigens using rapid diagnostic test kits. Descriptive statistics and chi-square were carried out on the GraphPad Prism 9 software with statistical significance defined as a p-value of less than 0.05 at a 95% confidence interval. Result: The prevalence of HIV from the current study was 6.5%, COVID-19 prevalence was reported to be 12.5% while HIV/COVID-19 co-infection was 1.5% The duration of incarceration, face mask use, frequent visitations and vaccination against COVID-19 were found to be significantly associated with the prevalence of COVID-19 in the studied population (p Conclusion: The current study reports a relatively high prevalence of HIV and COVID-19 among the inmates in the study area. It becomes expedient for the administrators of the correctional facility to properly screen new inmates for COVID-19, quarantine and manage cases, as well as provide them with personal protective equipment such as face masks. In-person visitation should be balanced with measures to prevent the spread of the infection, and mass vaccination campaigns should be promoted. Improving access to HIV screening and therapy for all prisoners should be prioritised to identify and manage the incidence of HIV early, reducing the risk of transmission, mitigating comorbidities and improving health outcomes.
文摘我是一名医生。最近在一些国内网站上读到一些鼓励oral sex的文章,文章鼓吹,只要将性器官洗净,口交也很卫生。7月5日晨我在Yahoo!上读到此文,医生的职业道德促使我把此文投稿给贵刊。文章的第一句就提醒我们:the risk of contracting HIV from oral sex is higher than many people think.
文摘China is currently experiencing one of the most rapidly expanding HIV epidemics in the world. Although the overall prevalence rate is still low, with a population of 1.3 billion, high-risk factors which have contributed to the HIV/AIDS epidemics worldwide continue to prevail in China, including a high rate of injecting drug use and needle sharing, commercial sex with low rates of condom use, and concurrent sex with both commercial sex workers and noncom- mercial casual or steady sex partners. In addition, there are increasing “double risk” populations overlapping drug users and sex workers, as well as increasing rates of STDs and HIV among high-risk populations. Sexual transmission, therefore, may serve as a bridge connecting high-risk populations with general populations. There is an urgent need to prevent the spread of HIV from these high-risk populations into the general population of China.
基金supported by National Natusal Seience Foundation of China (81001288)National S&T Major Project Foundation of China(No. 2008ZX10001-003+1 种基金 2009ZX10004-904)Universities National Science Foundation of Jiangsu Province (No. 09KJB330004)
文摘A cross-sectional study using the snowball sampling method was conducted in May 2008 to investigate human immunodeficiency virus (HIV) infection status and related high risk factors among men who have sex with men (MSM) in Suzhou city of Jiangsu province. The researchers carried out a face-to-face questionnaire interview among MSM, and collected their blood samples to test for HIV and other sexually transmitted diseases (STDs). Among the 280 respondents, 91.1% had homosexual acts in the past 6 months and 87.5% had multiple homosex- ual partners; 46.4% had heterosexual sex in the past 6 months and 33.1% had multiple heterosexual partners. The rate of continued condom use was 44.3% in homosexual sex in the past 6 months, while the rate in heterosexual sex was 33.9%. Laboratory test results showed that the prevalences of HIV and syphilis were 7.1% (20/280) and 15.0% (42/280), respectively, but no HCV-positive person was found. In the multivariate logistic regression model, subjects with a monthly income of more than RMB $ 1,000 (OR=4.83,95% CI=1.44-16.22), subjects who often went to bars for sexual partners (OR=2.25, 95%CI=1.21-4.20), and subjects who had more than one sexual partner in the past 6 months (OR=0.49, 95%CI=0.25-0.97) and had sex with fixed sexual partners in the past 6 months (OR=0.42, 95%CI=0.25-0.75) were significantly associated with the rate of continued condom use in homosexual sex in the past 6 months. Unprotected sex and multiple sexual partners were more common among MSM in Suzhou city; furthermore, the prevalences of HIV infection and syphilis were relatively high. HIV preventive measures should be designed to address these risk factors and control the spread of HIV among MSM.
文摘In Cameroon, despite extensive control efforts against HIV/AIDS, the number of new HIV infections is still on the rise. The factors contributing to this are not clearly understood. We hypothesized that it may lie on people living with HIV (PLHIV). In a case-control descriptive study, we studied the characteristics and sexual risky behaviour of PLHIV in the North West Region of Cameroon which has the highest HIV prevalence. Participants were screened for HIV and a structured questionnaire was used in data collection. An equivalent number (350) of PLHIV and controls who did not differ with respect to age and sex participated. Relative to the control, PLHIV were generally less educated (P < 0.001), poorer and less privileged (P < 0.001) with no stable source of income. Among participants that were once married, a greater proportion of PLHIV were divorced (OR = 5.23, P = 0.007), and widows (OR = 2.73, P = 0.001). Among participants that were single, a relatively greater proportion of PLHIV practiced multi-partner sex (OR = 4.55, P< 0.001). History of STDs was higher in PLHIV than the control (OR = 1.88, P = 0.001). Out of 350 PLHIV, 280 (80%) admitted to having had sexual intercourse after being diagnosed of which only 127 (41.78%) admitted to using condoms and 132 (47.14%) admitted to concealing their HIV status from their sexual partner(s). These findings have implications in HIV control programs which should target the poor and the less educated, as well as the sexual behaviour of PLHIV, so as to reverse the current rising trend of new infections in the country.
文摘The aim of this study was to determine the incidence rates of HIV1/2 antibodies, HBV and HCV antibodies among voluntary blood donors and to estimate the residual risk of HIV, HBV and HCV infection among blood donors in Bukavu. We conducted a follow-up cohort study of volunteer blood donors who have made at least two blood donations in Bukavu (DRC) between January 2010 and December 2012. We recorded 2986 volunteer blood donors during the study period. The residual risk of viral transmission associated with the serological window was considered as equals to the incidence rate multiplied by the duration of the serological window period divided by 365. Seroprevalence in volunteer blood donors in Bukavu was 1.1% for HIV 1/2 antibodies, 4.0% for HBs Ag and 2.1% for hepatitis C antibody. The number of conversion between two blood donations (incident cases) were observed is 8, 12 and 37 donors respectively for HIV 1/2, HCV and hepatitis B between 2010 and 2012. Incidence rates reported for 1000 person-years were 11.0 for HIV, 51.7 for HBV and 17.1 for HCV. The residual risk as estimated from the window was 0.6 per 1000 donations or 1/1.515 donations for HIV, 3.1 per 1000 donations or 1/329 for HCV and 7.9 per 1000 donations or 1/126 donations for hepatitis B. The residual risk is high. The screening tests are not enough to ensure safe blood. The reduction of residual risk would be achieved through the effectiveness of preventive measures taken for transfusion chain, before and after the biological qualification of blood donation.
基金Supported by Shanghai Municipal Health Bureau Foundation(08GWQ055)Shanghai Education Committee Foundation(10YS50)
文摘Objective To assess the HIV/STDs knowledge and risk behaviors related factors among female sex workers(FSWs)in Shanghai,China.Methods A cross-sectional study was conducted in 5 districts(including 3 suburbs and 2 urban districts).A total of 324 FSWs from 88 massage parlors and hair-beauty salons participated in the survey.An interviewer-administrated questionnaire was used to collect information.Results The average score of HIV/STDs knowledge was 15.2±3.9.Multivariate analyses indicated that limited education [odds ratio(OR):8.6,95% confidence interval(CI):2.9-25.6],coming from suburbs [odds ratio(OR):3.7,95% confidence interval(CI):2.0-6.8],monthly income less than 1500 RMB(220 US$)[odds ratio(OR):3.9,95% confidence interval(CI):1.9-8.1],without HIV/STDs-related education experience(OR:5.2,95% CI:2.8-9.5),and coming from provinces of low epidemic(OR:2.7,95% CI:1.1-6.6)were significant predictors of lower HIV/STDs knowledge.And 29.5% FSWs had sex without a condom when clients paid much more money,and 46.3% had the experience of condom broke or slipped during commercial sexual intercourse.Conclusion Health promotion should be conducted to enhance HIV/STDs knowledge and reduce risk behaviors among FSWs from suburbs with limited education in Shanghai especially.
文摘Background: Although much concern has been expressed about the occupational risk posed to surgeons by the HIV pandemic infection, the paediatric age group is often seen as less likely to harbor the disease. Aim: To determine the HIV infection rate among children presenting for surgical operations at the Lagos University Teaching Hospital (LUTH), Lagos. Materials, patients and method: Blood was taken from 1000 consecutive children referred to LUTH for surgical conditions and tested for HIV sero-positivity using the Western blot method. Consenting parents of sero-positive patients were also tested. Result: Five children tested positive for HIV, giving an overall infection rate of 0.5%. Four mothers and three consenting fathers were also positive. In one child, none of the parents was positive and he was suspected to have developed the disease from a previous blood transfusion prior to presentation in LUTH. This possibly resulted from transfusion of infected blood during its window period. Conclusion: Although the HIV infection rate of 0.5% in paediatric surgical group in Lagos is low, surgeons should vigilantly apply universal precautions to prevent needle-stick injuries while the rate of HIV infection should be periodically monitored to determine the trend.
文摘Diagnosis of sexually transmitted infections is very important considering the spread of HIV and the extensive use of highly active antiretroviral therapy worldwide. This will assist in planning of treatment schedule in controlling these infections. The study therefore aimed at determining the prevalence of syphilis in HIV positive antiretroviral therapy naive patients in Cape Coast and the associated risk factors involved in infection. A cross-sectional study was carried out using initial HIV rapid and confirmation tests, and then Venereal Disease Research Laboratory test with the Ultra Rapid Test Kits for syphilis. Demographic data, risky sexual behaviours capable of co-transmission of both HIV and Syphilis, were also collected through the use of questionnaires. In all, 150 HIV positive antiretroviral naive subjects were studied and 15 (10%) were positive for VDRL test, with females (6.00%) and males (4.00%), who were mainly within the age group of 20 - 39 years. A significant number of males (p = 0.019) and females (p = 0.015) participants were not smoking with a fewer number of the females (p = 0.002) having multiple sexual partners. Also a smaller number of those who were infected with the bacteria (p = 0.004) did not support the control of sexually transmitted infection (p = 0.022). The result showed that co-infection of Syphilis in HIV positive antiretroviral therapy naive patients persists in the Cape Coast Metropolis, which is an indication of prominence of STIs that require further study on a larger scale to ascertain the extent of co-infection and to formulate policy for treatment to help minimize the rate of infection.
文摘目的评估长沙地区2014年1月1日—2022年12月31日无偿献血者输血传播人类免疫缺陷病毒(h uma n immunodeficiency virus,HIV)残余风险。方法通过血站信息管理系统回顾性分析长沙血液中心2014年1月1日—2022年12月31日无偿献血者HIV血液筛查结果与疾病预防控制中心(CDC)反馈的确证结果,采用发病率-窗口期数学模型评估无偿献血者HIV筛查残余风险。结果研究期间长沙地区HIV确证阳性率为0.1995‰(273/1368333),其中初次献血者757455例,占比55.36%,确证阳性率0.2495‰(189/757455),重复献血者有610878例,占比44.64%,确证阳性率0.1375‰(84/610878),初次及重复献血者两组确证阳性率存在统计学差异(χ^(2)=21.270,P<0.001)。初次献血者HIV残余风险为1/204081.63高于重复献血者残余风险1/370370.37。如果只开展HIV血清学检测,窗口期参残余风险为1/85470,而增加HIV核酸检测血液筛查后,残余风险降低至1/250000,NAT筛查较血清学筛查能降低65.81%的残余风险。结论长沙地区无偿献血者输血传播HIV残余风险的评估有助于评价不同检测策略对血液安全的影响,保障血液质量。
文摘Objective: It is in order to estimate the prevalence and incidence of HIV, the frequency of sexual risk behaviors, and perceptions of available resources to prevent and treat HIV among crack users in the San Salvador Metropolitan Area. Methods: We conducted a survey of 420 crack users by using respondent-driven sampling to measure demographic characteristics, the quantity and frequency of drug use, history of STIs, including HIV, and experiences with organizations which provide prevention and treatment of HIV. Each participant offered a free and voluntary HIV test and was asked permission to share the results of the test with the study. Bernoullian modeling was used to estimate the prevalence and incidence of HIV among heterosexual males in this population. Results: The estimated prevalence was 7% (95% CI: 2.3% -9.8%) among participants who agreed to take the test and share the results, and 4.9% (95% CI: 2.8% -7.8%) assuming that those who did not take the test or share results were seronegative. Participants reported a high frequency of sexual risk behaviors. In addition, participants were reported to have little knowledge of organizations to prevent or treat HIV/AIDS;58% had never taken an HIV test prior to survey administration. Conclusions: Crack users in San Salvador are at high risk for HIV acquisition. HIV prevention interventions are urgently needed, especially interventions increasing access to HIV testing and prevention.
文摘According to current guidelines, exposing mucous membrane to blood and body fluids of HIV infected people is risk of transmission. About 30% - 80% of HIV infected people have at least one oral manifestation. The most frequently occurring oral manifestations (pseudomembranous candidiasis, linear gingival erythema, etc.) give rise to bleeding either spontaneously or after stimulation, and strenuous stirring during oral sex and deep-mouth kissing increase risk of bleeding from oral manifestations, exposing oral and genital mucous membrane of partners to the blood. However, current guidelines assert that there’s little to no risk of getting HIV from oral sex and deep-mouth kissing. These guidelines are conflict with each other, suggesting potential problems with current prevention strategies which are based on the guidelines. After discussing existing data on animals, lesbians, young peoples, and occupational exposures, this paper suggests oral sex and deep-mouth kissing are risk factors when one partner has HIV-associated oral bleeding manifestations, and the number of infections associated with oral sex and deep-mouth kissing is significant. Current guidelines on HIV risk factors should be reevaluated urgently, and new studies should be undertaken with an open mind to explore risk factors.