Validity and reliability of Chinese version of Fatigue Impact Scale in cerebral infarction patients

BACKGROUND： Post-stroke fatigue has received much attention recently. Three evaluation scales are available, including the Fatigue Impact Scale （FIS）. Yet none of these has been proven to be of use in the evaluation of psychological quality after post-stroke fatigue. OBJECTIVE： To introduce FIS into China, and to evaluate the validity and reliability of the Chinese Version in patients with cerebral infarction. DESIGN： Scale evaluation. SETTING： Department of Rehabilitation, Beijing Friendship Hospital, Capital Medical University. PARTICIPANTS： A total of 330 patients with cerebral infarction were selected from the Department of Neurology, Beijing Friendship Hospital, Capital Medical University from June 2005 to December 2006. All patients met diagnostic standards from the Fourth National Cerebrovascular Disease Academic Meeting of China Medical Association and were diagnosed with CT or MRI examination. Patients who were not willing to accept scale evaluation were excluded. METHODS： The English version of FIS was translated into Chinese and subsequently translated back to English again. FIS was given to the discharged patients, and they returned them upon completion. In-patients completed and immediately returned the FIS. Validity and reliability of the retrieved scales were ascertained with descriptive and inference analysis. MAIN OUTCOME MEASURES： Total scores and subscale scores of FIS. RESULTS： Out of 330 questionnaires, 214 valid questionnaires were deemed valid in total. Six components were extracted in factor analysis, and the total cumulative contribution was 73.919%, which suggested the questionnaire was valid. After correlation analysis, 6 components were divided into 3 subscales, including cognitive, physical, and social, which was the same as the English version. The Cronbach α value for the three subscales was 0.937 7, 0.918 8, and 0.940 6, respectively （〉 0.7）. CONCLUSION： The reliability and validity of the Chinese version of FIS met with satisfaction and appeared to be adaptable to cerebral infarction patients in China.

Research on Analytical Method of Fatigue Characteristics of Soft Yoke Mooring System Based on Full-Scale Measurement

By focusing on the vulnerability of the structure of marine equipments, together with considering the randomness of meta-ocean load in statistics, a kind of analytical method of fatigue characteristics of marine structure based on full- scale and actual measurement of prototype is proposed. On the basis of short-term field measurement results of structural response, research is carried out on the fatigue analysis of hinge joints at the upper part of the Soft Yoke single point Mooring System （SYMS） by simultaneously monitoring the environmental load and considering the design criteria of offshore structure. Through analysis of finite element modeling, the time-histories of typical stress response are obtained, and then the assessment of fatigue damage at key hinge joints is conducted. The simulation results indicate that the proposed method can accurately analyze the fatigue damage of offshore engineering structure caused by the effect of wave load. The present analytical method of fatigue characteristics can be extended on other offshore engineering structures subjected to meta-ocean load.

DIAGNOSTICS OF FATIGUE CRACK IN ULTERIOR PLACES OF LARGER-SCALE OVERLOADED SUPPORTING SHAFT BASED ON TIME SERIES AND NEURAL NETWORKS

To improve the diagnosis accuracy and self-adaptability of fatigue crack in ulterior place of the supporting shaft, time series and neural network are attempted to be applied in research on diag-nosing the fatigue crack’s degree based on analyzing the vibration characteristics of the supporting shaft. By analyzing the characteristic parameter which is easy to be detected from the supporting shaft’s exterior, the time series model parameter which is hypersensitive to the situation of fatigue crack in ulterior place of the supporting shaft is the target input of neural network, and the fatigue crack’s degree value of supporting shaft is the output. The BP network model can be built and net-work can be trained after the structural parameters of network are selected. Furthermore, choosing the other two different group data can test the network. The test result will verify the validity of the BP network model. The result of experiment shows that the method of time series and neural network are effective to diagnose the occurrence and the development of the fatigue crack’s degree in ulterior place of the supporting shaft.

Reliability and validity of the Chinese version of the PedsQL Multidimensional Fatigue Scale in children with acute leukemia

Background:The PedsQL Multidimensional Fatigue Scale(PedsQL^(TM)MFS)is widely used to rate fatigue in children living in English-speaking countries.However,insufficient instruments are available to conduct parallel assessment on fatigue in parents and children in China.In this regard,an appropriate measurement method must be developed.Objectives:This study aims to determine the reliability and validity of the Chinese-language PedsQL^(TM)MFS.Methods:Children with cancer(n=125)and their parents were surveyed in Guangzhou,China.The parents of children aged 2e4 years completed the PedsQL^(TM)MFS proxy reports,whereas the other children and their parents completed the questionnaires by themselves.Results:The PedsQL^(TM)MFS-Chinese version demonstrated satisfactory internal consistency reliability(child self-report Cronbach's a=0.87;parent self-report Cronbach's a=0.93).The factor loadings of the items ranged from 0.78 to 0.87 for general fatigue,0.56e0.78 for sleep/rest fatigue,and 0.62e0.89 for cognitive fatigue.Conclusion:This study proves that the PedsQL^(TM)MFS-Chinese version is an effective tool for screening fatigue in Chinese children with cancer.

Changes in mean cerebral blood flow velocity during cognitive task-induced cerebral fatigue in high performance fighter pilots

BACKGROUND： Several studies have demonstrated that sustained cognitive tasks can induce cognitive fatigue and that the mean cerebral blood flow velocity changes in some cerebral regions during cerebral fatigue. OBJECTIVE： To dynamically monitor the changes in mean cerebral blood flow velocity in different brain regions of high performance fighter pilots during mental arithmetic tasks and consecutive performance tasks. DESIGN, TIME AND SETTING： The present neurophysiological trial, based on controlled observation, was performed at the Laboratory of Neurophysiology, Institute of Aviation Medicine, Air Force of China between January 2003 and December 2005. PARTICIPANTS： Forty-five males, high performance fighter pilots, averaging （27.6±2.5） years, were recruited for this study. METHODS： The mean cerebral blood flow velocity in the anterior cerebral artery, middle cerebral artery, and posterior cerebral artery of subjects was dynamically tested using transcranial Doppler during 5- hour mental arithmetic tasks and during 5- hour consecutive performance tasks. The neurobehavioral ability index was analyzed throughout each trial according to the number of correct responses, false responses, and lost responses. Simultaneously, cerebral cognitive fatigue-induced lethargy was assessed by the Stanford Sleepiness Scale. MAIN OUTCOME MEASURES： Changes in mean cerebral blood flow velocity in the anterior cerebral artery, middle cerebral artery, and posterior cerebral artery; neurobehavioral ability index of mental arithmetic and consecutive performance tasks; Stanford Sleepiness Scale scores. RESULTS： During mental arithmetic tasks, the mean cerebral blood flow velocity in the anterior cerebral artery increased during hour 2 and decreased after hour 4. There was no significant change in mean cerebral blood flow velocity in the middle cerebral artery and posterior cerebral artery. During hour 4, cerebral cognitive fatigue was observed and, simultaneously, Stanford Sleepiness Scale scores demonstrated the presence of fatigue. During such a stage, the neurobehavioral ability index decreased, indicating a decline in performance ability. During consecutive performance tasks, the mean cerebral blood flow velocity declined earlier in the posterior cerebral artery compared to the middle cerebral artery. CONCLUSION： Five- hour mental arithmetic tasks have few effects on cerebral functions and do not lead to a significant change in mean cerebral blood flow velocity. Five-hour consecutive performance tasks can induce cerebral cognitive fatigue, and a marked decline in mean cerebral blood flow velocity.

Development of a Tool for Assessment of Post-Myocardial Infarction Fatigue

Introduction: After treatment for myocardial infarction (MI) quite a few persons will experience different symptoms, including fatigue, during the recovery phase. The aim of the present study was to construct the multidimensional Post-Myocardial Infarction Fatigue (PMIF) scale, based on empirical data gathered in coronary heart disease contexts. Methods: The construction of the post-MI fatigue scale was conducted in seven steps, ending in a psychometric evaluation of the internal structure of the scale, using confirmatory factor analysis, as well as testing of convergent and discriminant validity, using correlational analysis, in a sample of 141 persons treated for MI. Results: The results showed that the PMIF scale represents three dimensions: physical, cognitive and emotional fatigue. It was also found that the scale is suitable for summing the items to obtain a total score representing a post-MI global fatigue dimension. Conclusion: The PMIF is a brief and easily completed scale for identifying persons experiencing post-MI fatigue. Early identification of fatigue, together with health behavior support, might prevent progression toward a more severe state of fatigue.

Muscle fatigue in women with primary biliary cirrhosis:Spectral analysis of surface electromyography

瞄准：与健康题目相比与主要胆汁性肝硬变在病人评估外部易疲性的肌电表明。方法：有没有 comorbidity 的主要胆汁性肝硬变的十六个女人和好久匹配的 13 个健康女人和身体团索引(BMI ) 完成了自我报导的问询表疲劳影响规模。所有题目经历了对外部易疲性的表面肌电描记法评价。前面的胫骨的肌肉等轴的随意收缩在 80% 最大的自愿的等长收缩为 20 s 被执行。在锻练 electromyographic 信号期间，系列象 electromyographic 信号频率光谱(肌肉易疲性的估计) 的平均数和 median 一样被记录，根意味着平方(中央开车的表达式) 被计算。每个题目执行了试用 two times。EMG 参数被规范的、然后线性的回归被使用，斜坡是计算的。结果：七个病人被使疲劳(中部的疲劳影响规模分数：38，变化：26-66 ) 并且 9 没被使疲劳(中部的疲劳影响规模分数：7，变化：0-17 ) 。最大的自愿的等长收缩在病人是类似的(82， 54-115 N ) 并且控制(87， 74-101 N ) ，并且在有高度的病人(81， 54-115 N ) 并且低疲劳影响规模分数(86， 65-106 N ) 。方形以及频率光谱斜坡吝啬、中部的根平均数与 Mann-Whitney U 测试相比，并且没有有效差量被发现在之间使疲劳并且非使 \O 疲劳的病人和控制。结论：外部易疲性的仪器的证据都不能与主要胆汁性肝硬变而是没有 comorbidity 在女人被发现，建议在如此的病人的那疲劳可能具有中央起源。

Effect of Meridian Massage for Cancer Related Fatigue

Objectives:The purpose of this study is to investigate the effectiveness of meridian massage in lessening the fatigue and improving both physical and mental quality of life of cancer patients.Settings and design:This study was conducted at the East-West Cancer Center at Daejeon University;Using a single-arm,waiting list and non-treatment control research de- sign,we compared the results of control group and to that of the experimental group.Materials and methods:From July 2,2007 to July 28,2007,eighteen eligible cancer patients were recruited to participate in the experiment.Modified Chalder Fatigue Scale(CFS),Visual Analogue Scale(VAS)and active oxygen level were measured before and after treatment for both control and experimental groups.Lying on their back or stomach inside a room with a temperature of 18-22℃,the pa- tients received 30 minutes of meridian massages mainly around the trapezius muscles 5 times a week. Statistical analysis used:Data analysis was carried out using independent t-test,paired t-test and One-way ANOVA. Results:Data analysis of modified CFS showed statistically significant results for all groups between before and after treat- ment.Within CFS,results of physical and psychological analysis showed significant results for all groups except before and after no treatment and secondary treatment.In the analysis of VAS,the experimental group showed a greater decrease in score compared to that of the control group and the average difference was statistically significant(P<0.05).Although the results were not statistically significant(P>0.05),active oxygen levels for the control group showed little difference before and after no treatment(331.11 and 330.78,respectively)while the experimental group observed a decrease in active oxygen level before and after treatment(327.28 and 314.11,respectively).Conclusion:In conclusion,patients who received meridian massage showed decreased cancer related fatigue scores compared to the control.These results suggest that meridian massage may alleviate cancer-related fatigue and contribute to the improvement in quality of life among cancer patients.

多尺度聚丙烯纤维混凝土弯曲疲劳寿命试验及数值模拟

为研究多尺度聚丙烯纤维混凝土的弯曲疲劳性能,开展基准混凝土、聚丙烯粗纤维混凝土及多尺度聚丙烯纤维混凝土的静载试验及不同应力水平(0.75、0.80、0.85)下的弯曲疲劳试验,建立弯曲疲劳寿命方程,并结合ABAQUS与FE-SAFE软件建立纤维混凝土梁的三点弯曲疲劳有限元模型。结果表明:聚丙烯纤维的掺入,尤其是多尺度聚丙烯纤维混掺显著增强了混凝土基体的抗折、抗疲劳性能。双对数lgS-lgN疲劳方程能够较好地描述多尺度聚丙烯纤维混凝土的应力水平与疲劳寿命的相关性,使用lgS-lgN疲劳方程计算得到200万次循环荷载作用下多尺度聚丙烯纤维混凝土的疲劳强度最高,为3.91 MPa。三组试件疲劳寿命的数值模型预测值均介于实测疲劳寿命的最大值与最小值之间,并接近于疲劳寿命平均值,该模型为多尺度聚丙烯纤维混凝土的疲劳寿命预测提供了理论依据。

金属疲劳损伤全寿命过程及工程应用综述

金属疲劳损伤过程复杂,不同载荷类型与服役环境下金属疲劳损伤机理、变形特性和破坏模式存在较大差异。将疲劳损伤全寿命过程按照循环寿命周次划分为超高周、高周、低周和裂纹扩展4个类别,根据变形响应特性和变形机理特征阐述了各类别疲劳损伤的研究现状及发展趋势,涉及宏观尺度、微细观尺度和宏细微观多尺度理论体系。同时结合工程实际案例,以轧辊和燕尾榫作为代表性构件,分析其疲劳损伤行为与影响因素,探讨了目前疲劳理论在工程实践中的应用及挑战,旨在为金属疲劳损伤全寿命理论体系的完善和关键部件健康质量管控提供理论依据和技术指导。

沥青混合料弯曲疲劳损伤强度的多尺度研究

目的为了验证多尺度数值试验模拟方法在预测沥青混合料半圆弯曲试验疲劳损伤过程中弯拉强度参数变化规律的有效性问题。方法基于多尺度算法思想和半圆弯曲试验,通过对沥青混合料试件进行细观结构分析,得到内部集料颗粒的几何特征分布规律;在此基础上,对沥青混合料划分5个微观区域尺度,并构建相应尺度下半圆弯曲试件的有限元(FEM)数值模型,结合多尺度迭代运算来预测各级沥青混合料计算在0%Nf,20%Nf,50%Nf,65%Nf,80%Nf(Nf为疲劳寿命)不同半圆弯拉疲劳损伤程度下的弯拉强度。将室内半圆弯曲试验获得不同粒径的沥青混合料的弯拉强度参数作为宏观验证试验,与通过多尺度算法数值模拟试验所得的弯拉强度进行对比分析研究。结果结果表明:在沥青混合料的疲劳损伤过程中,前期材料的抗弯拉强度衰减速率较为缓慢,当在中后期时,抗弯拉强度进入了急剧衰减阶段,多尺度数值模拟试验与室内试验得到的衰减规律相吻合,且弯拉强度相对误差的绝对值控制在8%以内。结论多尺度数值模拟用于预测疲劳过程中沥青混合料的抗弯拉强度参数是有效的,该算法可以为类似的实际工程提供一定的参考意义。

新型钛合金焊接结构疲劳裂纹扩展速率试验研究

为了研究尺度效应及热处理工艺对新型钛合金材料疲劳性能的影响,本文对新型钛合金母材及焊接结构在不同尺度效应和热处理工艺下的力学性能和疲劳性能开展试验,分析尺度效应和热处理工艺对新型钛合金材料疲劳性能的影响规律。研究结果表明,仅经过低温热处理的新型钛合金焊接结构疲劳寿命要超过经过高温-低温热处理后的焊接接头近1.53倍;尺度效应对焊接结构的力学性能影响较大,对母材影响较小;随着尺度增大新型钛合金的裂纹扩展寿命增大,但裂纹扩展速率并无明显变化。

考虑车桥耦合及环境腐蚀的铁路钢桥疲劳分析

耐候钢通过改变合金元素以在其表面形成致密保护性防锈层因而具备良好的耐大气腐蚀性能,因此其在免涂装使用中为带锈工作,应用于公路和铁路桥梁中时可能存在腐蚀和疲劳耦合损伤问题。基于潍莱铁路线一座全焊接免涂装耐候钢桥开展列车动力作用下的关键构件和焊接节点疲劳损伤分析,并进行考虑腐蚀劣化影响下的疲劳寿命评估。基于列车-轨道-桥梁耦合系统模型研究在高速列车动力荷载下桥梁主桁关键构件动力响应并得到结构中最不利构件位置,分析关键构件在列车通行振动效应下的疲劳损伤度;结合考虑局部节点板精细化的多尺度耦合有限元模型,考虑轨道不平顺和列车运行速度的影响,得到桥梁节点板在不同速度下的疲劳损伤度;考虑环境腐蚀对桥梁疲劳寿命的影响,结合桥梁列车年运营量进行腐蚀环境下桥梁关键杆件和节点的疲劳使用寿命评估。研究结果表明:铁路钢桁梁桥在列车动力作用下不同构件的疲劳损伤不同,刚度较小以及应力响应影响线较短的构件疲劳损伤度更大,其中疲劳损伤度由大到小依次为节点横梁、腹杆、下弦杆、上弦杆。轨道不平顺和列车运行速度对桥梁节点板应力响应最大值影响并不显著,列车运行速度为120 km/h时与所分析桥梁共振更明显。环境腐蚀会降低铁路桥梁疲劳寿命,且对桥梁不同构件寿命影响程度不同。研究成果可为同类型铁路钢桁梁桥在腐蚀环境下的疲劳寿命评估和设计提供参考。

多尺度纤维对水泥基复合材料性能的影响

为准确掌握多尺度纤维对水泥基复合材料的性能影响规律,以碳酸钙晶须(calcium carbonate whisker,CW)纤维、钢纤维及聚乙烯醇(polyvinyl alcohol,PVA)纤维为基础,构建多尺度纤维水泥基复合材料,并在不同配合比条件下,通过流动性试验、单轴受压试验、三点弯曲缺口试验和叠加试验(overlay test,OT),研究多尺度纤维对水泥基复合材料力学性能、断裂性能及疲劳性能的影响规律.结果表明,多尺度纤维对水泥基复合材料的力学性能及断裂性能均具显著影响,在力学性能方面,多尺度纤维能较大程度上减弱水泥基复合材料的流动扩展度,并提高轴心抗压强度和弯曲抗拉强度;在断裂性能研究方面,单掺纤维组和混杂纤维组均能不同程度上提高水泥基复合材料的断裂性能.其中,对失稳断裂韧度和黏聚韧度的提升规律较为一致,在断裂性能指标的提升幅度上,黏聚韧度>失稳断裂韧度>起裂断裂韧度;CW纤维、钢纤维及PVA纤维的体积分数分别为0.50%、0.75%和0.25%时,水泥基复合材料的疲劳性能相对最优.研究成果可为水泥基复合材料的工程应用提供理论依据.

冠心病病人疲乏评估工具的研究进展

从单维度量表和多维度量表两个方面综述目前国内外应用于冠心病病人疲乏的评估工具,阐述各个量表的评估内容、信效度、应用情况及优缺点,以期为临床医务人员选择合适的评估工具和开发适用我国本土化的冠心病病人疲乏评估工具提供参考。

基于足尺节段模型的正交异性钢桥面疲劳性能

为了研究正交异性钢桥面的疲劳性能,根据新结构细部焊接工艺的研究成果和合理的结构参数,设计了足尺节段疲劳试验模型,通过足尺模型试验确定不同焊接工艺下各疲劳易损细节的实际疲劳抗力。铺装层作为钢桥面板之上的行车功能层,直接承担车辆轮载。分别设计了树脂沥青铺装和浇注式沥青铺装两种铺装结构,进行武汉市江汉七桥铺装层与正交异性钢桥面板协同受力体系的模型试验,并考虑温度的影响。研究结果表明:有铺装层的钢桥面板U肋与顶板构造细节,由于铺装层与钢桥面板的协同作用,其应力幅值相较于无铺装层时显著降低;该应力幅值随着铺装层温度的升高而增大。

基于心率变异性的长航时模拟飞行疲劳评估

目的分析长航时模拟飞行中执行夜间飞行任务的驾驶员的状态,初步对受试者夜间执行任务的状态和可能预警点进行评估。方法选取8名健康男性,每2人一组分别执行机长和副机长的任务,共4组,开展模拟48 h连续飞行任务,其中,机长和副机长进行轮班制度,每飞行4 h进行45 min的睡眠以及45 min的恢复,根据该模拟飞行任务中所采集的心电数据,利用心率变异性(HRV)方法对试验对象的疲劳程度进行分析。结果HRV指标区分疲劳与非疲劳状态准确率大于90%的段落主要分布在夜间,且上半夜相较于下半夜飞行员的疲劳程度更大,试验第2日相较于第1日飞行员疲劳感更为明显。结论HRV分析体现了不同状态下的自主神经系统变化,通过结合相关分类模型,可靠地区分了模拟飞行试验中飞行员的疲劳与非疲劳状况。

不同方法对盲人足球运动员运动疲劳监测的比较研究

目的:探讨下肢爆发力下降率(下降成绩/训练前成绩)、体重流失率(流失体重/训练前体重)、训练疲劳积累评分(主观疲劳量表训练后评分-训练前评分)三种方法监测运动疲劳的效率。方法:以中国国家男子盲人足球队15名运动员为实验对象(国际健将4人;国家健将10人,无等级1人。年龄25.6±5.28岁;身高1.762±0.049米;体重70.93±7.61千克;BMI指数22.95±1.81;训练年限8.8±3.54年)。通过实验测试获取运动员下肢爆发力下降率、体重流失率以及训练疲劳积累评分数据,然后将三项指标分别与自身血清睾酮/皮质醇(T/C值)进行相关分析。结果:运动员下肢爆发力降低率与T/C值有着近似线性的负相关关系(|R|=|-0.981|﹥0.70);体重流失率与T/C值存在高度的负相关关系(|R|=|-0.924|﹥0.70);训练疲劳积累评分与T/C有非常高度的负相关关系(|R|=|-0.718|﹥0.70)。结论:(1)下肢爆发力下降率监测法准确度高于体重流失率与训练疲劳积累评分监测法,且体重流失率监测法效率优于训练疲劳积累评分监测法;(2)针对盲人运动员,下肢爆发力下降率运动疲劳监测法测试是一项省时省力、简单易行、安全可靠的生理指标监测方法,具有精准度高、相对成本低、即刻知晓结果的优势。

肿瘤幸存者癌因性疲劳综合评估量表的编制与初步应用

目的编制肿瘤幸存者癌因性疲劳综合评估量表,并对评估量表信度、效度进行初步应用。方法以不愉快症状理论为基础生成量表症状评估核心指标,结合相关文献并通过前期部分肿瘤幸存者的认知访谈内容,初步编制条目池,通过2轮专家咨询,并对出现癌因性疲劳的245例肿瘤幸存者进行量表信度、效度检验。结果最终修订的肿瘤幸存者癌因性疲劳综合评估量表包括32个条目,探索性因子分析提取8个公因子,累积方差贡献率为70.454%;条目水平内容效度指数为0.827~1.000,量表水平内容效度指数0.924;量表Cronbach′sα系数为0.893,Spearman-Brown分半信度系数为0.796。结论肿瘤幸存者癌因性疲劳综合评估量表具有较好信度、效度,可作为肿瘤幸存者癌因性疲劳的测评工具。