葡甘露聚糖抑菌护理凝胶(Glucomannan antibacteria care gel,GACG)是本课题组开发的一款已上市的治疗女性阴道炎症的抑菌护理剂。本文介绍了GACG的制备工艺,通过建立高危型HPV 16假病毒感染人胚肾293FT细胞模型,重点研究GACG的主要活...葡甘露聚糖抑菌护理凝胶(Glucomannan antibacteria care gel,GACG)是本课题组开发的一款已上市的治疗女性阴道炎症的抑菌护理剂。本文介绍了GACG的制备工艺,通过建立高危型HPV 16假病毒感染人胚肾293FT细胞模型,重点研究GACG的主要活性成分白芨葡甘露聚糖、积雪草总苷和蛇床子精油对高危型人乳头瘤病毒16(Human papillomavirus type 16,HPV 16)的抗病毒作用。研究发现积雪草总苷和蛇床子精油对高危型HPV 16假病毒具有明显的抗病毒活性,分子对接进一步探究了积雪草苷、羟基积雪草苷以及蛇床子素对HPV 16抑制的可能机制。展开更多
In this study 82 bioely tissues of cervical cancer were examined for the Presence of HPV16 E6 gene by PCR.the Positive rate was 73.2%(60/82).The HPV 16 E6 DNA amplified by PCR waslabeled and used as probe to detect HP...In this study 82 bioely tissues of cervical cancer were examined for the Presence of HPV16 E6 gene by PCR.the Positive rate was 73.2%(60/82).The HPV 16 E6 DNA amplified by PCR waslabeled and used as probe to detect HPV E6 gene in the sam.specimens by dot-blot bybridization,thepositive rate was 54.9(45/82).Our rescults showed that the peltive rate of detectiod of HPV 16 E6gene was high in cervical cancer tissue of the Chinese women and cofirmed the close association ofHPV 16 E6 gene with development of cervical cancer.展开更多
文摘In this study 82 bioely tissues of cervical cancer were examined for the Presence of HPV16 E6 gene by PCR.the Positive rate was 73.2%(60/82).The HPV 16 E6 DNA amplified by PCR waslabeled and used as probe to detect HPV E6 gene in the sam.specimens by dot-blot bybridization,thepositive rate was 54.9(45/82).Our rescults showed that the peltive rate of detectiod of HPV 16 E6gene was high in cervical cancer tissue of the Chinese women and cofirmed the close association ofHPV 16 E6 gene with development of cervical cancer.
