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The Occurrence of Longfengshania in the Early Cambrian from Haikou, Yunnan, China 被引量:4
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作者 徐兆良 《Acta Botanica Sinica》 CSCD 2002年第10期1250-1254,共5页
Well preserved Early Cambrian small individual megascopic carbonaceous algal fossils have been found from the Chengjiang Biota. This paper deals with the new megascopic algal fossils in the Early Cambrian also from Ch... Well preserved Early Cambrian small individual megascopic carbonaceous algal fossils have been found from the Chengjiang Biota. This paper deals with the new megascopic algal fossils in the Early Cambrian also from Chengjiang Biota at Ercai Village, Haikou, Kunming, Yunnan, southwest China. Two new taxa, Longfengshania cordata sp. nov. and Plantulaformis sinensis gen. et sp. nov. are described here in detail. These new findings show that the Chengjiang Biota is high in species diversity of fossil algae and might offer new evidence for a better understanding of the Cambrian explosive biological evolution. Moreover, the fossils described here might belong to the megaalgal fossils according to detailed morphological study on the relationships of Longfengshania. Additionally, the occurrence of Longfengshania in the early Cambrian and the Neoproterozoic probably indicates a wide ecological tolerance and flexibility and apparently reflects its evolutionary conservation and a high degree of inherent genetic stability. 展开更多
关键词 haikou of Kunming Early Cambrian algal fossils
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New Discoveries of Phaeophycean Fossils in the Early Cambrian, Haikou, Kunming,Yunnan, Southwest China 被引量:1
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作者 徐兆良 《Acta Botanica Sinica》 CSCD 2001年第10期1072-1076,共5页
The paper deals with the new phaeophycean fossils in the Early Cambrian from Chengjiang Biota at Ercai Village of Haikou, Kunming, Yunnan, Southwest China. Three new taxa, Punctatiopsis latifolia gen. et sp. nov., P. ... The paper deals with the new phaeophycean fossils in the Early Cambrian from Chengjiang Biota at Ercai Village of Haikou, Kunming, Yunnan, Southwest China. Three new taxa, Punctatiopsis latifolia gen. et sp. nov., P. simplex gen. et sp. nov. and Vendotaenia cf. antiqua Gnilovskaya axe described here in detail. These new findings show that the Chengjiang Biota is high in species diversity of fossil algae and might offer new evidence for a better understanding of the Cambrian explosive biological evolution. The fossil genus described here is found to have a close relationship with the living Punctatia based on similar morphology. The results suggest that the Chengjiang Biota in Haikou area of Kunming was living in an intertidal and subtidal seawater environment. 展开更多
关键词 haikou of Yunnan Early Cambrian phaeophycean fossils
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Study on Landscape of Arcaded Old Streets in Haikou
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作者 刘拥春 周金镍 《Journal of Landscape Research》 2010年第6期43-47,51,共6页
Arcaded old streets are the historical witness of Haikou City transforming from an ancient town into the prosperous coastal commercial city,and they are the important content of international tourism island constructi... Arcaded old streets are the historical witness of Haikou City transforming from an ancient town into the prosperous coastal commercial city,and they are the important content of international tourism island construction.Although arcaded old streets are still the important hopping places for Haikou people,the crowded streets and backward and shabby residential and commercial conditions couldn't meet people's needs.The shopping environment without entertainment deviates from people's original shopping intention.The building facades,green space,public rest space and municipal facilities are less than satisfactory.The street landscape has gradually declined.So we must take restoration measures to protect them and create arcaded streets with local characteristics.For example,to restore the faade,dredge flowing space,create space for leisure,sort out all kinds of advertisement facilities,rebuild municipal facilities,add environmental facilities and so on. 展开更多
关键词 haikou ARCADE STREETS LANDSCAPE SPACE
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New Early Cambrian Chordates from Haikou, Kunming 被引量:12
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作者 LUO Huilin, HU Shixue and CHEN Liangzhong Yunnan Institute of Geological Sciences, 131 Baita Road, Kunming 650011, Yunnan 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2001年第4期345-348,共4页
Two new chordates, Cathaymyrus haikouensis Luo et Hu sp. nov. and Zhongxiniscus intermedius Luo et Hu gen. et sp. nov. are studied in this paper. Both display numerous S-shaped myomeres on their trunk. C. haikouensis ... Two new chordates, Cathaymyrus haikouensis Luo et Hu sp. nov. and Zhongxiniscus intermedius Luo et Hu gen. et sp. nov. are studied in this paper. Both display numerous S-shaped myomeres on their trunk. C. haikouensis shows a long and slim body similar to that of Cathaymyrus diadexus Shu et al., Zhongxiniscus approaches to Myllokunmingia and Haikouichthys in the dorsal fin, but differs in the myomeres. Zhongxiniscus may be the intermediate form between Cathaymyrus and Myllokunmingia and Haikouichthys. 展开更多
关键词 haikou Kunming Early Cambrian CHORDATE
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香蕉束顶病毒Haikou2分离物DNA2编码框原核表达及抗血清制备
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作者 谭老喜 王洪星 +5 位作者 张雨良 王健华 章绍延 周朋 余乃通 刘志昕 《热带作物学报》 CSCD 北大核心 2012年第12期2246-2251,共6页
香蕉束顶病毒(Banana bunchy top virus,BBTV)是危害香蕉的主要病毒之一,严重威胁着香蕉的生产。BBTV基因组至少由6个环状ssDNA组分组成,其中DNA2组分变异最大,是否编码蛋白及其功能缺乏研究。本研究通过PCR方法克隆了BBTV Haikou2 DNA2... 香蕉束顶病毒(Banana bunchy top virus,BBTV)是危害香蕉的主要病毒之一,严重威胁着香蕉的生产。BBTV基因组至少由6个环状ssDNA组分组成,其中DNA2组分变异最大,是否编码蛋白及其功能缺乏研究。本研究通过PCR方法克隆了BBTV Haikou2 DNA2 ORF,将其构建到pET32a载体中,进行原核表达和抗血清制备。结果表明重组表达载体pET32a-DNA2ORF在表达菌Transetta(DE3)中表达一个约21 ku的特异融合蛋白,通过超声波破碎仪破碎细胞和诱导条件优化,分析表明,该蛋白主要以可溶形式存在,最佳表达条件为30℃、1.0 mmol/L IPTG诱导3 h。融合蛋白经过Ni2+-NTA琼脂糖亲和层析纯化,免疫家兔制备出抗血清。Western blot实验表明抗血清具有特异性;酶联法(ID-ELISA)测定表明,抗血清效价达到25 000,能够检测出香蕉汁液中加入的0.954μg/mL浓度的表达纯化蛋白。 展开更多
关键词 香蕉束顶病毒haikou2分离物 BBTVDNA2 原核表达 抗血清制备
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Behavior features of heavy metals in the Haikou Bay waters 被引量:4
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作者 Chen Chunhua Wang Zhengfang and Lu Haiyan 1. Marine Exploitation Plan and Design Research Institute of Hainan Province, Haikou 570203, China 2. Second Institute of Oceanography, State Oceanic Administration, Hangzhou 310012, China (Received July 12, 1996 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1999年第2期247-255,共9页
Dissolved Cu, Ph, Zn and Cd in the Haikou Bay waters were measured to be respectively in the range concentrations of 0.47-1.16 μg/dm^3, 0. 94-- 2. 36μg/dm^3, 1.28-4.83 μg/dm^3 and 0. 005-0.072μg/dm^3; with respect... Dissolved Cu, Ph, Zn and Cd in the Haikou Bay waters were measured to be respectively in the range concentrations of 0.47-1.16 μg/dm^3, 0. 94-- 2. 36μg/dm^3, 1.28-4.83 μg/dm^3 and 0. 005-0.072μg/dm^3; with respectively average values of 0.78μg/dm^3, 1.36μg/dm^3, 3.14 g/dm^3 and 0. 03 μg/dm^3. Dissolved Cu and Zn concentrations are relatively high at the stations near the Longkun Road Outfall for domestic sewage, the Xiuying Outfall for industry waste water and the Haidian Island Estuary, but dissolved Pb and Cd concentrations are low in these stations. The values in Other stations are comparatively homogenous. Vertical dissolved Cu, Pb and Zn concentrations at the bottom layer are higher than at the surface layer, but dissolved Cd concentration appears to be on the opposite. The measurement results of Cu, Pb, Zn and Cd in suspended particle show that particulate matters in the Haikou Bay seawater play a role in purifying heavy metals. The study on strong complexed form and non-liable form of dissolved copper show that the ratio of strong complexed form and dissolved form is about 85%, and non-liable form is very low with a value lower than 5 nmol/dm^3. Therefore, copper in the Haikou Bay seawater cannot cause influence on marine organisms. 展开更多
关键词 haikou Bay seawater heavy metal behavior feature
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A discussion on typhoon occurred in the Haikou Bay and impact mechanism on seawater quality 被引量:1
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作者 Chen Chunhua, Li Qiaoxiang 1.Marine Exploitation Plan & Design Research Institute of Hainan Province, Haikou 570203, China 2.Marine Monitoring Center of Hainan Province, Haikou 570011, China 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2001年第3期355-362,共8页
Water quality parameters such as pH, DO, COD, PQ4 - P, SiO3 - Si, NO2 - N, NO3 -N in the Haikou Bay were monitored respectively before and after Typhoon 9618 occurring on Sep. 18, 1996. Based on the statistics of typh... Water quality parameters such as pH, DO, COD, PQ4 - P, SiO3 - Si, NO2 - N, NO3 -N in the Haikou Bay were monitored respectively before and after Typhoon 9618 occurring on Sep. 18, 1996. Based on the statistics of typhoon in the Haikou Bay and numerical calculation of stormy current, the mechanism of water quality variation caused by typhoon is discussed. The typhoon impact on the Haikou Bay usually appears between July and November, most usually between August and October. The monitoring results before a typhoon were different from that. The stormy wave and windstorm cur-rent stir up the sediment in near-shore bottom and make the bottom water mix with the surface water strongly, specially windstorm current with strong velocity at the head of the bay stirs up higher pollutants sediment near sea area of sewage outfall, and heavy rain with typhoon carries the pollutants from land through the Nandu River to the Haikou Bay, so the contents of COD, PO4 - P, NO4 - N, NO3 ~N, SiO3 after a typhoon are higher than those before. Windstorm current is violent, which makes offshore high DO water exchange more frequently with inner bay water and oxygen in the air dissolves in sea water faster, so DO content after typhoon is higher than that before typhoon. This strong action of water exchange also causes lower pH change before and after the typhoon. 展开更多
关键词 The haikou Bay TYPHOON seawater quality impact mechanism
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AstudyonseawaterapparentheavymetalcomplexationcapacityintheHaikouBay
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作者 Chen Chunhua(Received October 10, 1996 $$ accepted April 4. 1997) 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1998年第3期327-336,共10页
Using semidifferential stripping technique combined with pre-equilibrium complexometric titration, theabnormal phenomena appeared in determining apparent complexation capacity ( ACC) are discussed and the improvedmeth... Using semidifferential stripping technique combined with pre-equilibrium complexometric titration, theabnormal phenomena appeared in determining apparent complexation capacity ( ACC) are discussed and the improvedmethod for determinimg ACC is presented in the article. The accuracy of ACC measurement results is tested theoreti-cally and experimentally . Based on determination of ACC Cu, ACC Pb and ACC Cd, copper was selected for complexo-metric titration to determine ACC and the results are proved to be reasonable. ACC Cu measured in the Haikou Bay sur-face water is in the range of 166 . 4  ̄ 320 . 2 nmol/dm3, with the mean value of 240 . 9 nmol/dm3, the maximum valuearound domestic drainage outfall, and the values in other stations are comparatively homogenous. The condition forma-tion constant is in the range of 3 . 46 x 107  ̄ 4 . 76 x 108, and the mean value is 1 . 7 x 108 . Based on the 1 : 1 comlexingmodel of copper-natural organic ligand and the toxic concentration limit to marine organisms, seawater self-purificationcapacity in the Haikou Bay is calculated to be 7 . 43 ug/dm3 . 展开更多
关键词 The haikou Bay heavy metal AAC seawater
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GIS- and RS-based Analysis of Suburban Landscape Layout in Haikou City
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作者 XIE Genzong LI Pengshan +2 位作者 SU Shan MENG Xiangcai LI Min 《Journal of Landscape Research》 2013年第4期1-4,8,共5页
Landsat TM/ETM+ and Alos remote sensing data of the study area in 1991, 2001 and 2010 were interpreted by using object-oriented RS image extraction technology, landscape ecology theories were applied as well as GIS an... Landsat TM/ETM+ and Alos remote sensing data of the study area in 1991, 2001 and 2010 were interpreted by using object-oriented RS image extraction technology, landscape ecology theories were applied as well as GIS and FRAGSTATS4.1 to choose reasonable landscape indexes for studying temporal-spatial changes of suburban landscape layouts of Haikou City, exploring spatial features and change tendency of rural landscapes. According to the results, tropical garden landscapes have taken a dominant status in the last 2 decades; tropical farmland landscapes have had the most complicate shapes; tropical open forest landscapes have been most influenced by human interventions but had the best connectivity and high degree of concentration; tropical settlement landscapes and tropical meadow landscapes have been widely scattered with poor connectivity; landscape connectivity has been well maintained; contagion index has changed slightly, landscape equilibrium has been stable; landscape diversity has been maintained, all landscape types have been evenly distributed, landscape fragmentation has increased, and landscape heterogeneity has grown. 展开更多
关键词 SUBURBS of haikou CITY RURAL landscapes Spatial distribution LANDSCAPE layout
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Analysis of the Freezing Damage to Biennial Eucalyptus dunnii and Eucalyptus smithii in Haikou Forest Farm
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作者 Yan Yi Wang Youbing +2 位作者 He Yinzhong Zhou Qinghong Wang Yating 《Meteorological and Environmental Research》 CAS 2014年第8期31-33,38,共4页
In winter of 2013,cold weather occurred in Kunming,and biennial E. dunnii and E. smithii in Haikou Forest Farm suffered different degrees of freezing damage. The freezing damage to them was analyzed here. The results ... In winter of 2013,cold weather occurred in Kunming,and biennial E. dunnii and E. smithii in Haikou Forest Farm suffered different degrees of freezing damage. The freezing damage to them was analyzed here. The results showed that in the families of E. dunnii,families suffering severe and especially severe freezing damage accounted for 7. 7%,while 92. 3% of families suffered moderate and below freezing damage; in the families of E. smithii,56. 7% of families suffered severe and especially severe freezing damage,while families suffering moderate and below freezing damage accounted for 43. 3%. There was significant difference between two species of eucalyptuses in tree height( P 〈0. 05),while there was extremely significant difference in freezing damage grade and index( P 〈0. 01). There was significantly negative correlation between the tree height and freezing damage grade of E. dunnii and E. smithii,with the correlation coefficients of- 0. 374 and- 0. 234. That is,the freezing damage grade would decrease with the increase of tree height. 展开更多
关键词 EUCALYPTUS haikou Forest Farm Freezing damage Freezing index China
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Analysis of hyperuricemia in physical examination population of a hospital in Haikou
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作者 Xiao-Bo Tang Ying-Zi Lin +6 位作者 Liu-Ting Liu Chan-Juan Zhao Cheng-Xian Huang Lan Huang Wu-Jian Xie Jun-Cai Chen You-Xuan Yan 《Journal of Hainan Medical University》 2022年第14期30-34,共5页
Objective:Explore the influencing factors of Hyperuricemia(HUA)in natural people aged 35-74 in Haikou.Methods:Between June 2017 and December 2020,8754 different study subjects aged 35-74 years were enrolled for the ba... Objective:Explore the influencing factors of Hyperuricemia(HUA)in natural people aged 35-74 in Haikou.Methods:Between June 2017 and December 2020,8754 different study subjects aged 35-74 years were enrolled for the baseline survey at the physical examination center of a tri partite hospital in Haikou.Results:Overall detection rate of HUA was 18.5%,including 25.6%in male and 10.4%in female.HUA detection rates varied between the 35-45 and 46-55 age groups(P<0.05).The binary logistic results showed that high blood pressure,triglyceride,low density lipoprotein and creatinine were the risk factors of HUA(P<0.05).Conclusions:The baseline survey results show that the detection rate of HUA in a hospital in Haikou is relatively high.Men and groups with high blood pressure,creatinine,triglyceride and low-density lipoprotein should be the key groups for the early prevention and treatment of hyperuricemia(HUA). 展开更多
关键词 haikou Baseline survey HYPERURICEMIA Influencing factors
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Effectiveness Evaluation of the Construction of the Natural Forest Resources Protection Project in Haikou Forest Farm of Kunming
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作者 ZHANG Zhihong WANG Yating +1 位作者 CHEN Jinlong YAN Yi 《Journal of Landscape Research》 2018年第2期42-44,共3页
The current situation about the natural forest resources protection project in Haikou Forest Farm of Kunming on the protection of forest resources, forest fire prevention, forest administration resource management, fo... The current situation about the natural forest resources protection project in Haikou Forest Farm of Kunming on the protection of forest resources, forest fire prevention, forest administration resource management, forest pests, and money management was briefed. Achievements made in the implementation of natural forest protection project in Haikou Forest Farm were analyzed, and problems existing in the project as well as corresponding countermeasures were expounded. 展开更多
关键词 haikou Forest Farm Natural forest protection project Effectiveness evaluation SUGGESTION
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Study on sea water pollution mechanism of Xiuying Bathing Beach in Haikou
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作者 Chen Chunhua Wang Lu and Wang Daoru(Ocean Exploitation Planning and Design Research Instituteof Hainan, Haikou 570203, China) 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1996年第3期397-408,共12页
关键词 Study on sea water pollution mechanism of Xiuying Bathing Beach in haikou
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National Standardization Conference 2003 held in Haikou
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《China Standardization》 2004年第1期12-13,共2页
关键词 2003 National Standardization Conference 2003 held in haikou
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Diversity of wood-decaying fungi in Haikou Forestry Farm,Yunnan Province,P.R.China
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作者 He X Chen JZ Zhao CL 《Studies in Fungi》 2021年第1期365-377,共13页
Nine field trips carried out in Haikou Forestry Farm,Yunnan Province,P.R.China resulted in 681 specimens of wood-decaying fungi.The present paper summarizes 52 species collected that are distributed in 37 genera,16 fa... Nine field trips carried out in Haikou Forestry Farm,Yunnan Province,P.R.China resulted in 681 specimens of wood-decaying fungi.The present paper summarizes 52 species collected that are distributed in 37 genera,16 families,6 orders including their hosts and substrates.A checklist of wood-decaying fungi in Haikou Forestry Farm is also given.Phylogenetic analysis of ITS nrRNA gene region was performed for all the collected samples with maximum likelihood,maximum parsimony and Bayesian inference methods.The phylogenetic tree showed that fifty-two species nested in sixteen families belonging to six orders in Agaricomycetes. 展开更多
关键词 BASIDIOMYCOTA biological resources DIVERSITY haikou Forestry Farm mycota
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The 3^(rd) Cotton School Successful Held in Haikou in April
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《China Textile》 2010年第5期12-12,共1页
COTTON USA Cotton School 2010 was successfully held in Haikou,China,on 22nd and 23rd April 2010.The event received an overwhelming feedback from the industry and attracted more than 150 guests from the US and China to... COTTON USA Cotton School 2010 was successfully held in Haikou,China,on 22nd and 23rd April 2010.The event received an overwhelming feedback from the industry and attracted more than 150 guests from the US and China to attend.The representatives of Embassy of the United States of America,Agricultural Affairs Offices in Beijing and Guangzhou also took part in the school. 展开更多
关键词 SCHOOL The 3 rd Cotton School Successful Held in haikou in April
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2020—2022年海口市城区大气PM_(2.5)中重(类)金属组成及来源解析
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作者 何昌华 杨夕 +8 位作者 伍燕春 胡伟 封丹 唐天统 林天 符桂林 李永忠 梅振坤 曾月 《环境卫生学杂志》 2024年第10期802-811,共10页
目的探析海口市主城区大气PM_(2.5)中重(类)金属污染的组成和主要来源。方法于2020—2022年对海口市主城区进行逐月定期(10—16日)采集大气PM_(2.5)样品,每日持续采样时间不少于22 h;利用电感耦合等离子体质谱法(ICP-MS)测量PM_(2.5)样... 目的探析海口市主城区大气PM_(2.5)中重(类)金属污染的组成和主要来源。方法于2020—2022年对海口市主城区进行逐月定期(10—16日)采集大气PM_(2.5)样品,每日持续采样时间不少于22 h;利用电感耦合等离子体质谱法(ICP-MS)测量PM_(2.5)样品中25种重(类)金属成分;对PM_(2.5)中检出率较高的16种重(类)金属成分采用正定矩阵因子分解模型(PMF)解析主要污染来源。结果2020—2022年海口市主城区大气PM_(2.5)质量浓度范围4.00~64.00μg/m^(3),均数(x±s)为(20.48±12.88)μg/m^(3)、中位数(M)17.00μg/m^(3)及四分位数间距(IQR)14.25μg/m^(3),年度间PM_(2.5)24小时平均浓度差异不具有统计学意义(χ^(2)=1.24,P>0.05);不同季节PM_(2.5)24小时平均浓度差异具有统计学意义(χ^(2)=44.86,P<0.01),PM_(2.5)24小时平均浓度(均数)高低顺序为冬季>秋季>春季>夏季;16种重(类)金属的质量浓度范围为0.01~1008.00 ng/m^(3),质量浓度M值由高到低依次为Fe>Al>Zn>Mn>Pb>Ba>Cu>Sr>Ni>Se>V>As>Sn>Cr>Cd>Li。PMF模型解析结果表明,PM_(2.5)中16种重(类)金属污染主要贡献来源以道路及土壤尘源(49.82%)和交通尾气源(36.96%)为主,次之贡献源有混合燃烧源(9.61%)、建材施工尘源(2.51%)和船舶燃油源(1.10%)。结论2020—2022年海口市大气PM_(2.5)质量浓度均未超过我国《环境空气质量标准》(GB 3095-2012)24小时平均浓度二级限值(75μg/m^(3))水平,PM_(2.5)中重(类)金属构成主要以Fe、Al、Zn、Mn和Pb元素为主,其主要贡献源是道路及土壤尘源和交通尾气源。 展开更多
关键词 海口 细颗粒物 重(类)金属 源解析
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中华文化建设视角下的海口传统歌谣研究
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作者 张继焦 张禹 《海南师范大学学报(社会科学版)》 2024年第3期121-131,共11页
中华文化建设旨在传承和弘扬中华民族的优秀传统文化,而海口传统歌谣作为一种传统口头文化,记录着海口、海南及中国特殊时期的印记,恰是其重要组成部分,值得被更多地关注。但现阶段,一方面,社会中愈发多元的文化形态借助大众传播媒介充... 中华文化建设旨在传承和弘扬中华民族的优秀传统文化,而海口传统歌谣作为一种传统口头文化,记录着海口、海南及中国特殊时期的印记,恰是其重要组成部分,值得被更多地关注。但现阶段,一方面,社会中愈发多元的文化形态借助大众传播媒介充斥着人们的眼球,冲击着传统歌谣的生存空间;另一方面,关于海口传统歌谣的保护与研究还九牛一毛,因此海口传统歌谣研究工作急需跟进。文章提出研究歌谣的“三结构”框架,即以“全国歌谣—地方歌谣—区域歌谣”为视角,觇其在中华文化符号不同体系中的位置。最后结合新海口传统歌谣发展的态势,从自生层面探讨海口传统歌谣在中华文化大背景下承载的更多意义,以使海口传统歌谣这一文化符号薪火相传、继往开来。 展开更多
关键词 海口传统歌谣 文化建设 系统论 新古典“结构-功能论”
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基于营口城市更新的海口检疫医院及门诊楼建筑复原研究
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作者 莫娜 赵聪 《沈阳建筑大学学报(社会科学版)》 2024年第4期333-339,347,共8页
营口海口检疫医院是近代东北海关检疫最重要的历史建筑,在近代中国检疫建筑史中具有重要的历史价值、科学价值与文化价值。对海口检疫医院基址在营口城市肌理中的演变进行了分析,并对海口检疫医院相关文献史料中的建筑演变过程、建筑功... 营口海口检疫医院是近代东北海关检疫最重要的历史建筑,在近代中国检疫建筑史中具有重要的历史价值、科学价值与文化价值。对海口检疫医院基址在营口城市肌理中的演变进行了分析,并对海口检疫医院相关文献史料中的建筑演变过程、建筑功能以及门诊楼风格与尺度等进行了梳理,形成了海口检疫医院的初步复原设计方案。海口检疫医院门诊楼专业性的防疫检疫功能在当时的中国具有一定的先进性,门诊楼的复原设计可以为营口城市更新提供历史建筑再生与活化的实践依据。 展开更多
关键词 城市更新 东北 营口海口检疫医院 防疫建筑 门诊楼 复原研究
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5636例疑似地中海贫血样本的异常血红蛋白分子特征及外周血参数分析 被引量:1
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作者 王婵 黄邓高 +4 位作者 冯女 张淑芳 刘海芳 唐小燕 陈扬 《海南医学》 CAS 2024年第4期521-526,共6页
目的 了解可疑罹患(或携带)地中海贫血(简称“地贫”)基因人群中异常血红蛋白基因携带率、异常血红蛋白突变类型及其复合地贫时的分子特征和血细胞参数变化。方法 对中南大学湘雅医学院附属海口医院2016年10月至2022年8月5 636例疑似地... 目的 了解可疑罹患(或携带)地中海贫血(简称“地贫”)基因人群中异常血红蛋白基因携带率、异常血红蛋白突变类型及其复合地贫时的分子特征和血细胞参数变化。方法 对中南大学湘雅医学院附属海口医院2016年10月至2022年8月5 636例疑似地贫受试者的样本采用高通量测序技术进行基因检测,对检测出的异常血红蛋白的样本及其血细胞参数进行回顾性分析。结果 5 636例疑似地贫样本中共检出异常血红蛋白46例,检出率为0.82%,突变类型有10种,分别是Hb Owari、Hb HekinanⅡ、Hb Port Phillip、Hb Saclay、Hb New York、Hb Hamilton、Hb J-Bangkok、Hb Shizuoka、Hb Zengcheng和Hb Hachioji;不同异常血红蛋白之间血液表型差异较大,其中Hb New York、Hb HekinanⅡ、Hb Hamilton、Hb Owari、Hb J-Bangkok五组血细胞参数[平均红细胞体积(MCV)、平均红细胞血红蛋白(MCH)、平均红细胞血红蛋白浓度(MCHC)、血红蛋白(Hb)和红细胞分布宽度(RDW)]比较差异均有统计学意义(P<0.05),Hb HekinanⅡ的MCV、MCH、MCHC和Hb平均值最低,Hb Hamilton的四种血细胞参数平均值最高;RDW的数据显示HB New York最高,其次是Hb HekinanⅡ,第三是Hb J-Bangkok,平均值均高于正常范围;性别间的血细胞参数比较差异无统计学意义(P>0.05);异常血红蛋白患者无论是合并α-地贫基因型还是β-地贫基因型,与单纯的异常血红蛋白组相比,血细胞参数差异均无统计学意义(P>0.05)。结论 疑似地贫基因的样本中异常血红蛋白突变类型较多,且有罕见基因型;异常血红蛋白的血细胞参数变化不同,或可为地贫的致病机制找到新的思路。 展开更多
关键词 海口 异常血红蛋白 地中海贫血 高通量测序 血液学指标
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