Effect of heat-producing needling technique on the local skin temperature:A clinical study

Objective:This clinical study was performed to examine the influence of heat-producing acupuncture(HPA)treatment on the local skin temperature of Zusanli(足三里ST36)acupoint in healthy participants.Methods:30 healthy participants received four successive sessions of heat-producing acupuncture(HPA),non-acupoint HPA(NAHPA),normal stable acupuncture(Norm)and non-invasive sham acupuncture(Sham)on the ST36 acupoint in random order.Within each treatment session,the local skin temperature of ST36 acupoint and basal body temperature of each participant were measured at 1 min before needle insertion(T1 B),just after needle insertion and manipulation(T0),5 min after needle insertion(T5)and 5 min after needle removal(T5 A).Visual Analogue Scale(VAS)scores of the participants’perceived needling and heat sensation felt during the acupuncture treatment period(T0-T5)were also recorded on a scale of 1 to 10.Results:Intra-session group statistical analyses of the different time points in the HPA treatment session group demonstrates that ST36 local skin temperature remained relatively stable between T1 B and T0,increased significantly between T0 and T5 and decreased significantly between T5 and T5 A.For intersession group statistical analysis of all treatment session groups,the increase in local skin temperature of ST36 acupoint between T0 and T5 in the HPA treatment session group was significantly higher than those of the NAHPA treatment session group(P<0.01),Norm treatment session group(P<0.01)and Sham treatment session group(P<0.01).The decrease in local skin temperature of ST36 acupoint between T5 and T5 A in the HPA treatment session group was also significantly more than those of NAHPA treatment session group(P<0.05),Norm treatment session group(P<0.01)and Sham treatment session group(P<0.001).Conclusion:Our study provides evidence that HPA treatment performed significantly better than the other three treatments in elevating the local skin temperature of ST36 acupoint temporarily.Our results also align with those of many previous clinical studies on HPA and related acupuncture manipulations.

CLINICAL AND ELECTROPHYSIOLOGICAL OBSERVATIONS ON DIABETIC PERIPHERAL NEUROPATHYTREATED BY WARM NEEDLING AND MOXIBUSTION

Objective To observe clinical therapeutic effects of warm needling and moxibustion on diabetic peripheral neuropathy （DPN） and their influence on nerve conduction velocity. Methods Fifty two cases were randomly divided into a treatment group （n =26） and a control group （n =26）. In addition to basic treatment for lowering blood sugar in both groups, Pǐshū （BL 20）, Shènshū （BL 23）, Huántiào （GB 30）, Zùsānlǐ （ST 36）, Yánglíngquán （GB 34）, Sānyīnjiāo （SP 6）, Tàixī （KI 3）, Qǔchí （LI 11）, Wàiguān （TE 5） and Hégǔ （LI 4） were selected for warm needling and moxibustion in the treatment group. Methycobal was intramuscularly injected in the control group. Clinical symptoms and conduction velocities of the tibial nerve and common peroneal nerve were compared before and after treatment. Results Warm needling and moxibustion could alleviate such clinical symptoms as numbness of limbs, pain and hypoesthesia, and obviously improve the conduction velocities of both tibial and common peroneal nerves. Conclusion Warm needling and moxibustion exhibit good therapeutic effects on diabetic peripheral neuropathy.

INTRODUCTION TO PROF. YANG YUN-KUAN'S THE NEEDLING TECHNIQUE OF MIND REGULATION AND TAOISM CONCENTRATION

The combination of needling technique of Mind Regulation with Taoism Concentration is to promote the propagated sensation along the channels （PSC） and the needling sensation to the affected area in order to activate the potential regulation of human body. Prof. Yang Yun-kuan used this combination to treat some pain diseases, nervous system＇s diseases and intractable chronic diseases and got a better result than the general techniques, This is the introduction to the manipulation of this technique and its clinical application.

AN OBSERVATION OF THE THERAPEUTIC EFFECT OF WARMING NEEDLING TECHNIQUE ON JIAJI POINTS FOR THE TREATMENT OF DEPRESSION AND ITS INFLUENCE ON EEG-α WAVE IN PATIENTS

Objective To discuss the therapeutic effect and mechanism of warming needling technique for the treatment of depression. Methods A total of 60 patients with depression were randomly divided into treatment group and control group with 30 cases each. The treatment group was treated with warming needle technique on the Jiaji points of the heart, lung, liver, spleen and kidney, control group with Amitriptyline, HAMD scale and the qualitative change of EEG-α wave were observed before and after the treatment. Results The total effective rate of treatment group was 100%, much better than that of the control group with 80% (P<0.05); the HAMD scale of treatment group was better than that of control group (P<0.05); the comparison of the improvement of somatic symptoms between treatment group and control group was significant (P<0.05); the comparison of frequency and amplitude of EEG-α wave was significant (P<0.05), there was no toxic and side effect in the treatment group. Conclusion Warming needling technique for depression has better effect than Amitriptyline, and there was no toxic and side effect in the treatment group. Warming needle technique can effectively regulate the frequency and amplitude EEG-α wave, and acts to improve depressive condition.

Dry needling at myofascial trigger points mitigates chronic post-stroke shoulder spasticity

Post-stroke spasticity is associated with restriction in the range of motion of the shoulder.Reducing muscular dystrophy may help relieve muscular dysfunction in patients with post-stroke shoulder spasticity.Dry needle therapy is a method of needling the trigger points using a syringe needle without the use of a drug.Dry needle therapy is commonly used for pain at the shoulder,neck,waist,and back.In this case study,a 62-year-old male patient affected with cerebral hemorrhage of the right frontal lobe had received rehabilitative treatment for 12 years.However,he still experienced shoulder spasticity.The patient received daily dry needling at the trigger points of infraspinatus,teres minor,posterior deltoid,and pectoralis major on 9 days.After the first and ninth treatment,the Modified Ashworth Scale and the passive range of motion of the shoulder was used to assess the effect of the treatment.The spasticity and range of motion of the shoulder showed obvious improvement.These results indicate that dry needling at the myofascial trigger points can effectively treat chronic poststroke shoulder spasticity.

Xingnao Kaiqiao needling method for acute ischemic stroke： a meta-analysis of safety and efficacy

OBJECTIVE： To evaluate the effectiveness and safety of the Xingnao Kaiqiao needling method for treating acute ischemic stroke.DATA SOURCES： We retrieved relevant randomized controlled trials involving Xingnao Kaiqiao acupuncture for treatment of acute ischemic stroke. The China National Knowledge Infrastructure, Weipu Information Resources System, Wanfang Medical Data System, Chinese Biomedical Literature Database, Cochrane Library, and Pub Med were searched from June 2006 to March 2016.DATA SELECTION： We analyzed randomized and semi-randomized clinical controlled trials that compared Xingnao Kaiqiao acupuncture with various control treatments, such as conventional drugs or other acupuncture therapies, for treatment of acute ischemic stroke. The quality of articles was evaluated according to the Cochrane Handbook for Systematic Reviews of Interventions（Version 5.1）, and the study was carried out using Cochrane system assessment methods. Rev Man 5.2 was used for the meta-analysis of the included studies.OUTCOME MEASURES： The mortality rate, disability rate, activities of daily living（Barthel Index）, and clinical efficacy were observed.RESULTS： Twelve studies met the inclusion criteria for this review. The meta-analysis showed that between Xingnao Kaiqiao acupuncture and the control treatment, Xingnao Kaiqiao acupuncture reduced the disability rate [risk ratio（RR） = 0.51, 95% confidence interval（CI） = 0.27-0.98, z = 2.03, P 〈 0.05], elevated the activities of daily living（weighted mean difference = 12.23, 95% CI： 3.66-20.08, z = 2.80, P 〈 0.005）, and had greater clinical efficacy（RR = 1.61, 95% CI： 1.23-2.09, z = 3.53, P 〈 0.0004）. However, there was no significant difference in mortality rate（RR = 0.61, 95% CI： 0.15-2.45, z = 0.70, P 〉 0.05）. CONCLUSION： The Xingnao Kaiqiao needling method is effective and safe for acute ischemic stroke. However, there was selective bias in this study, and the likelihood of measurement bias is high. Thus, more high-quality randomized controlled trials are needed to provide reliable evidence of the efficacy and safety of Xingnao Kaiqiao acupuncture in the treatment of acute ischemic stroke.

Bleb needling outcomes for failed trabeculectomy blebs in Asian eyes: a 2-year follow up

·AIM: To describe the outcomes of bleb needling in primary glaucoma in an Asian tertiary eye centre over a2 y period. To compare the success rates between primary angle-closure glaucoma(PACG) and primary open angle glaucoma(POAG). Lastly, to identify factors associated with success of bleb needling.·METHODS: This was a retrospective review of 227 patients who underwent bleb needling between June2009 and June 2011 in Singapore National Eye Centre.The 5-fluorouracil(5-FU) augmented bleb needling was performed either at the slit lamp or in the operating theatre. Repeat bleb needlings were performed as necessary. Complete success was defined as maintenance of intraocular pressure(IOP) ≥6 mm Hg and ≤21 mm Hg, in the absence of further surgery or use of antiglaucoma medication. Qualified success met the above criteria with or without use of antiglaucoma medications.· RESULTS: One hundred and seventy-five eyes completed the two-year follow up. Sixty-nine percent of participants had POAG and 31% had PACG. The mean interval between filtering surgery and bleb needling was299.9 ±616.4d for POAG and 167.1 ±272.2d for PACG.Mean needling attempts were 1.9±1.4 and 2±1.6 for POAG and PACG respectively. In general, there was a statistically significant reduction of IOP ranging from21.9% to 26.8% from month 1 through to month 24. The complete success rates at month 6 were 70.0% for POAG and 65.7% for PACG. At month 12, this decreased to62.2% for POAG and PACG and at month 24, 57.9% for POAG and 63.0% for PACG respectively. The qualified success rates at month 6 for POAG and PACG were23.8% and 29.9% respectively, 32.2% and 29.2% at month12, and 34.7% and 29.6% at month 24. The success ratesbetween POAG and PACG were not significantly different(P 】0.05 for complete and qualified success at months 6,12 and 24). An increased number of needlings and higher pre-needling IOP were associated with failure.·CONCLUSION: The 5-FU augmented bleb needling within one year of trabeculectomy in Asian eyes can provide clinically significant IOP lowering of more than20% for 2y. POAG and PACG had similar complete success rates(58% and 63% respectively). Factors associated with greater risk of procedure failure included increased number of needlings and higher pre-needling IOP. Asian eyes have a greater propensity for scarring but bleb needling, if performed in a timely manner can rescue bleb function.

Specific cerebral activation following true and sham Waiguan(SJ 5) needling Functional magnetic resonance imaging evidence

Positive activation and negative activation of glucose metabolism can be detected in different brain regions under acupuncture conditions using functional magnetic resonance imaging （fMRI） which reveals acupoint function and location-acupoint specificity. This study observed the regional cerebral activation of the Waiguan （SJ 5） acupoint following true needling at the true Waiguan acupoint, sham needling at the true Waiguan acupoint and true needling at a sham point using fMRI. The fMRI results demonstrated that compared with sham needling, true needling at Waiguan activated the BA8 area and left cerebellum. Compared with needling at the sham point, needling at Waiguan activated the BA2 area, the left cerebellum and the right inferior semilunar lobule. Thus the activated brain areas caused by needling Waiguan may be the basis for treatment of certain diseases.

Systematic review of long-term Xingnao Kaiqiao needling efficacy in ischemic stroke treatment

OBJeCTIve：To systematically evaluate the long-term effect and safety ofXingnao Kaiqiao nee-dling method in ischemic stroke treatment. DATA ReTRIevAL： We retrieved relevant random and semi-random controlled trials that used theXingnao Kaiqiao needling method to treat ischemic stroke compared with various control treatments such as conventional drugs or other acupuncture therapies. Searched databases included China National Knowledge Infrastructure, Weipu Information Resources System, Wanfang Medical Data System, Chinese Biomedical Literature Database, Cochrane Library, and PubMed, from May 2006 to July 2014. SeLeCTION CRITeRIA： Two authors independently conducted literature screening, quality evaluation, and data extraction. The quality of articles was evaluated according to the Cochrane Reviewers’ Handbook 5.1, and the study was carried out using Cochrane system assessment methods. RevMan 5.2 was used for meta-analysis of the included studies. MAIN OUTCOMe MeASUReS： Mortality rate, recurrence rate, and disability rate were observed. ReSULTS：Nine randomized and semi-randomized controlled trials treating 931 cases of ischemic stroke were included in this review. Meta-analysis results showed that there were no sig-niifcant differences in mortality reduction （risk ratio （RR） = 0.58, 95% conifdence interval （CI）： 0.17–1.93,Z = 0.89,P = 0.37） or recurrence rate （RR = 0.55, 95%CI： 0.18–1.70,Z = 1.04,P = 0.30） of ischemic stroke patients between theXingnao Kaiqiao needling and control treatment groups. However, theXingnao Kaiqiao needling method had a tendency towards higher efifcacy in mor-tality reduction and recurrence rates. TheXingnao Kaiqiao needling method was signiifcantly better than that of the control treatment in reducing disability rate （RR = 0.51, 95%CI： 0.27–0.98, Z = 2.03,P 〈 0.05）. CONCLUSION：TheXingnao Kaiqiao needling method has a better effect than control treatment in reducing disability rate. The long-term effect ofXingnao Kaiqiao needling against ischemic stroke is better than that of control treatment. However, the limitations of this study limit the strength of the conclusions. Randomized controlled trials with a strict, reasonable design, and multi-center, large-scale samples and follow-up are necessary to draw conclusions aboutXingnao Kaiqiao needling.

STUDY ON THE THERAPEUTIC EFFECT AND MECHANISMS OF ELECTRO-THERMAL NEEDLING FOR TREATMENT OF VULVAL LEUKOPLASIA

In the present paper,444 patients with vulvar leukoplasia were treated by selectingacupoints in the local area and along the meridian plus Qugu（CV 2）and Huiyin（CV 1）and usingelectro-thermal needling.The total effective rate was up to 100.0％and the cure rate 87.3％.Theelectro-thermal effect directly acted on the affected area but strengthened the immunologic function ofthe whole body and raised the content of serum copper.

改进型超声引导下针状可视肾镜(Needle perc)钬激光碎石术治疗肾下盏结石的临床评价:与输尿管软镜对比

目的比较改进型超声引导下针状可视肾镜(Needle perc)钬激光碎石术和输尿管软镜下钬激光碎石术治疗1~2 cm肾下盏结石的效果,为临床治疗方式的选择提供参考。方法回顾性分析2022年1月—2023年5月郑州市第一人民医院收治的60例肾内单发下盏结石(最大径1~2 cm)患者的临床资料,比较行输尿管软镜钬激光碎石术的30例患者(软镜组)和改进型超声引导下Needle perc钬激光碎石术的30例患者(Needle perc组)的临床资料。结果Needle perc组较软镜组的整体住院时间[(3.00±1.25)d vs.(4.00±1.25)d]、手术时间[(44.63±5.42)min vs.(48.50±7.24)min]和住院花费[(15518±441)元vs.(16872±903)元]均较少(P<0.05)。Needle perc组术后清石率高于软镜组[93.3%(28/30)vs.50.7%(15/30),P<0.001]。术后降钙素原(PCT)上升幅度低于软镜组[(0.02±0.01)vs.(0.12±0.18),P=0.007],而并发症发生率低于软镜组[3.3%(1/30)vs.26.7%(8/30),P=0.030]。结论对于1~2 cm的肾下盏单发结石,改进型超声引导下Needle perc钬激光碎石术清石率较高、并发症发生率低,安全且有效。

Surrounding Needling with Fire Needle and Filiform Needle Plus Moxibustion in the Treatment of Lower Limb Herpes Zoster:One Case Report

Introduction Herpes zoster is a skin disease caused by activation of the varicella zoster virus,which is latent in neurons.It can be accompanied by severe neuralgia.Some herpes zoster patients may have pain allergy,general discomfort,loss of appetite and other prodromal symptoms,typical clinical manifestation as a cluster of blisters distribution along unilateral peripheral nerve,often accompanied by obvious neuralgia[1].

EFFECT OF NEEDLING SENSATION REACHING THE SITE OF DISEASE ON THE RESULTS OF ACUPUNCTURE TREATMENT OF BRONCHIAL ASTHMA

Effective treatment of bronchial asthmawith various methods of acupuncture has beenreported in the literature.The present articlediscusses the results of the treatment of bron-chial asthma(BA)and chronic senile bronchitis(CSB)according to the phenomenon of needlingsensation reaching the site of disease during acu-puncture.

BRIEF INTRODUCTION TO THEORETICAL INTENTION OF "NEEDLING METHOD FOR TRANQUILLIZATION AND CALMING THE MIND" FOR TREATMENT OF INSOMNIA

A set of scientific theories and an effective acupuncture therapy for insomnia about ＂the needling method for tranquillization and calming the mind＂ are gradually formed through many years＇theoretical and clinical studies. In this paper, the theoretical intention about ＂the needling method for tranquillization and calming the mind＂ for treatment of insomnia are briefly introduced mainly from the cause of disease, pathogenesis, therapeutic method and characteristics of composition of a prescription, etc. in order to provide a new train of thoughts and a new method for working out scientific and standard prescriptions in the treatment of insomnia.

Effect of cluster needling at scalp acupoints on differential protein expression in rat brain tissue after acute focal cerebral ischemia

Objective:To explore the function of cluster needling at scalp points therapy on regulating differential protein's expression at different time points in middle cerebral artery occlusion(MCAO)model rats.Methods:Fifty-four rats were divided into three groups randomly and 18 rats in each group.The groups respectively were the model group(group M,n=18),cluster needling at scalp points group(group C,n=18),false operation group(group F,n=18).Each group was then assigned in three subgroups,including 24-h,7-day,and 14-day subgroups.Six rats in each subgroup.Acupuncture at Baihui(GV20)and 2 points beside Baihui,which was 3 e4 mm away from the midline.Longa score was used to evaluated neurological effects.Proteomics methods were used to identify differentially expression proteins with a standard of fold change greater than 1.5 and P<.05 at different times.Results:1.Nerve function scoring:The nerve function scores at 7 and 14 days decreased in group C,which showed better neural function than group M(P<.05).2.Fold change in proteins:Group M showed932 differentially expressed proteins compared with group F,and among them,414 proteins showed significant changes in expression after acupuncture.The expression levels of Cdc42 and GFAP were increased,and Mag,Shank2,and MBP levels were decreased.In the Gene Ontology analysis,the cellular component consisted of the terms cytoplasm,cytoskeleton,lysosome,and plasma membrane.The main related biological processes were cellecell signaling,protein transport,aging,and cell adhesion.Many synaptic and metabolic pathways were found by KEGG analysis.Conclusion:Cluster needling at scalp acupoints can improve the nerve function score and improve dyskinesia in MCAO model rats.Cluster needling at scalp acupoints can regulate the expression of 414 proteins,including Cdc42,GFAP,Mag,Shank2,and MBP,which are related to cerebral ischemia.The differential proteins are major concentration in cytoplasm,cytoskeleton,lysosomes,and plasma membrane,participate in cellecell signaling,protein transport,aging,and cell adhesion,and act through multiple synaptic and metabolic pathways to exert their biological functions.

TREATMENT OF 36 CASES OF SCAPULOHUMERAL PERIARTHRITIS MAINLY BY CONTRALATERAL NEEDLING

Objective: To analyze the therapeutic effect of contralateral needling in the treatment of scapulohumeral periarthritis. Methods: A total of 68 cases of scapulohumeral periarthritis were outpatients and were randomized into treatment group (n=36) and control group (n=32). In treatment group, Zhiyin (BL 67), Jinmen (BL 63) and Yanglao (SI 6) on the contralateral side of the affected shoulder and local tenderpoints (Ashi-points) were punctured once every other day, with 7 days being a therapeutic course; while in control group, local Ashi-points were used for injection of Procaine and Prednisolone Acetate, once every 7 days and with 3～4 sessions being a therapeutic course. Results: Following 2 courses of treatment, of the 32 cases in control group, 8 (25.0%) were cured, 17 (53.1%) experienced improvement and 7 failed in the treatment, with a total of effective rate of 78.1%; of the 36 cases in treatment group, 18 (50.0%) were cured, 16 (44.4%) experienced improvement and 2 (5.6%) failed in the treatment, with a total effective rate of 94.4%. The therapeutic effect of contralateral needling is significantly higher than that of Ashi-point blocking method (P<0.05). Conclusion: Contralateral needling is superior to Ashi-point in the treatment of scapulohumeral periarthritis.

OBSERVATION ON THE EFFECT OF SHALLOW NEEDLING FOR TREATMENT OF PERIPHERAL FACIAL PARALYSIS IN 80 AFRICANS

This paper is a summary of 150 cases of facial paralysis in African black people treated with shallow needling and mild needling manipulation. After 3 courses of treatment, of the 80 cases in the shallow-needling group, 71 (88. 8% ) were cured, 5 (6. 3% ) had marked improvement, 3 (3. 7% ) had improvement and 1 (1. 2% ) failed; Of the 70 cases in traditional-needling group, 61 (87. 1 % ) were cured, 6 (8. 6% ) had evident improvement, 2 (2. 9% ) had improvement and 1 (1. 4 % ) had no striking change. Statistical analysis showed no significant difference between the two groups in the therapeutic effect (P >0. 5 ), indicating both the traditional needling method and shallow needling were effective in treatment of facial paralysis in black people. In addition, earlier treatment was very important in healing facial palsy; and the cure rate was higher in younger patients ard those with light severity.

ANALYSIS ON THERAPEUTIC EFFECTS OF 46 CASES OF PERIARTHRITIS OF SHOULDER TREATED BY NEEDLING JIANSANZHEN WITH MAGNETIC POLE NEEDLE AND MASSAGE

In the present paper,46 cases of periarthritis of shoulder were treated by needlingthe Jiansanzhen with magnetic pole needle and massage. Among them,43 cases were cured, ac-counting for 93. 48% and 46 were effective. The total effective rate was 100%. In control groupI there were 23 cases, who received treatment of acupuncture with traditional stainless-steel fili-form needle and massage, the total effective rate was 91. 3%. Comparison of the therapeutic ef-fects between the two groups showed X^2=4. 12, P【0.05. In control group II there were 23 cas-es, who received needling Tiaokou point (ST 38)-through-Chengshan (BL 57) with the abovementioned stainless-steel filiform, one of ancient and modern experimental methods, the total ef-fecive rate was 82. 6%, which was compared with that in the treatment group, indicating X^2=8.492, P【0. 01. It is suggested that the therapeutic effect in the treatment group was superior tothat in the control group I and significantly superior to that in the control group II.

CLINICAL OBSERVATION ON PENETRATION NEEDLING TREATMENT OF 65 CASES OF HYPERTENSION

The present paper reports the results of 65 hypertension patients treated with pene-tration needling（point through point method in acupuncture）.For comparison,other ps cases ofhypertension were treated with routine needling method.Changes of blood pressure were ob-served before,during and after treatment.Results showed that the hypotensive effect of the pen-etration needling was significantly superior to that of the routine acupuncture（P【0.05）.Thefollowing-up survey 3 months after treatment showed significant differences between two groupsand between post-treatment and pre-treatment in each group in the mean vahes of systolic and di-astolic pressure（P【0.05）.It reveals that acupuncture has a good hypotensive action,and thepenetration needling is of a certain long-term therapeutic effect.

CLINICAL OBSERVATION ON TREATMENT OF 198 CEREBRAL INFARCTION PATIENTS WITH OPPOSING AND NON-OPPOSING NEEDLING METHODS

198 cases of cerebral infarction diagnosed clinically.by means of CT scan wereselected, and the therapeutic effects obtained with the methods of opposing and non-opposing needlingwere compared, The primary points included Head-Linqi(GB 15) and Zhengying(GB 17) (penetra-tion needling), Fengchi(GB 20), Neiguan (PC 6), qnd Yinlingquan (SP 9). While the supplemen-tary points were Jiquan (HT 1 ), Xiaohai (SI 8), Huantiao (GB 30), Yinmen (BL 37), Sanyinjiao(SP 6), and Taixi (KI 3). It was found that the radical cure rate in the group treated with opposingneedling was 57%, while that in the group with non-opposipg needling was 34%. The difference oftherapeutic effects between the two groups was of statistical significance (P【0.01 ). It indicates thatopposing needling is superior to non-opposing needling in elevating cure rates and reducing sequelae.