Subsequent studies have demonstrated the reversed activity of the aqueous extract of Ceiba pentandra on the deformity of sickled red blood cells in hypoxia conditions. The observation which related to an in vitro stud...Subsequent studies have demonstrated the reversed activity of the aqueous extract of Ceiba pentandra on the deformity of sickled red blood cells in hypoxia conditions. The observation which related to an in vitro study had given rise to hopes as to the management of sickle cell disease (SCD) by the use of this plant species. In this paper, the authors aimed to investigate the effect of the aqueous extract of C. pentandra on the production of fetal hemoglobin in SCD patients. The work carried out hemoglobin electrophoresis, for a period of six months, on blood samples from SCD patients who voluntarily undergone routine treatment, based on the medicinal recipe prepared from the bark of the trunk and branches of C. pentandra, in a hospital center of herbal medicines located in Kinshasa. The medicinal recipe called BEAT-SS is a patented product of the hospital center named Centre de Phytothérapie Moderne NIECA. Blood samples from patients under treatment were taken to evaluate the behavior of different forms of hemoglobin (hemoglobin S, hemoglobin F and hemoglobin A2). Agarose gel electrophoresis with integrated reading was used for the separation of the different forms of hemoglobin, as well as their dosage on each sample of sickle blood. A reduction in the proportion of hemoglobin S and an increase in the proportion of fetal hemoglobin were found in all sickle cell patients during the treatment period. This observation could affirm that the management of sickle cell patients using the recipe prepared from the aqueous extract of C. pentandra could increase the level of fetal hemoglobin in these patients.展开更多
目的探讨HBs Ag酶联免疫试剂检测试管血和导管血S/CO的差异性。方法厦门新创HBs Ag ELISA试剂检测2015年1月1日至2015年4月30日无偿献血者标本17967例,对初次反应性标本用原试管和血袋导管血分别进行双孔复试。结果检测17967例标本,共...目的探讨HBs Ag酶联免疫试剂检测试管血和导管血S/CO的差异性。方法厦门新创HBs Ag ELISA试剂检测2015年1月1日至2015年4月30日无偿献血者标本17967例,对初次反应性标本用原试管和血袋导管血分别进行双孔复试。结果检测17967例标本,共检测阳性标本143例,阳性率为0.8%。试管血与导管血S/CO≥28有56例,10≤S/CO<28间的有40例,1.5≤S/CO<10的有36例,0.8≤S/CO<1.5的有11例。采用T检验,10≤S/CO<28间的40例和1.5≤S/CO<10的36例,0.8≤S/CO<1.5的11例,导管血S/CO均明显低于试管血。结论除强阳性标本外,导管血S/CO明显低于试管血,为保证血液结果的准确性,对初次反应性处于灰区的标本不适于单独使用导管血进行复查。展开更多
本文报道49例Hb G Coushatta在我国西北部的分布情况。新疆和甘肃的发生率为0.57‰和0.43‰,高于陕西的发生率0.07‰。维吾尔、哈萨克、柯尔克孜和回族的发生率为0.66‰—1.74‰,高于汉族的发生率0.45‰。Hb G Coushatta基因流呈由北向...本文报道49例Hb G Coushatta在我国西北部的分布情况。新疆和甘肃的发生率为0.57‰和0.43‰,高于陕西的发生率0.07‰。维吾尔、哈萨克、柯尔克孜和回族的发生率为0.66‰—1.74‰,高于汉族的发生率0.45‰。Hb G Coushatta基因流呈由北向南和向西漂移和特点,结合国内外有关资料进行分析,这种变异体起源于东北亚地区,为古代游牧民族的遗传标志。展开更多
文摘Subsequent studies have demonstrated the reversed activity of the aqueous extract of Ceiba pentandra on the deformity of sickled red blood cells in hypoxia conditions. The observation which related to an in vitro study had given rise to hopes as to the management of sickle cell disease (SCD) by the use of this plant species. In this paper, the authors aimed to investigate the effect of the aqueous extract of C. pentandra on the production of fetal hemoglobin in SCD patients. The work carried out hemoglobin electrophoresis, for a period of six months, on blood samples from SCD patients who voluntarily undergone routine treatment, based on the medicinal recipe prepared from the bark of the trunk and branches of C. pentandra, in a hospital center of herbal medicines located in Kinshasa. The medicinal recipe called BEAT-SS is a patented product of the hospital center named Centre de Phytothérapie Moderne NIECA. Blood samples from patients under treatment were taken to evaluate the behavior of different forms of hemoglobin (hemoglobin S, hemoglobin F and hemoglobin A2). Agarose gel electrophoresis with integrated reading was used for the separation of the different forms of hemoglobin, as well as their dosage on each sample of sickle blood. A reduction in the proportion of hemoglobin S and an increase in the proportion of fetal hemoglobin were found in all sickle cell patients during the treatment period. This observation could affirm that the management of sickle cell patients using the recipe prepared from the aqueous extract of C. pentandra could increase the level of fetal hemoglobin in these patients.
文摘目的探讨HBs Ag酶联免疫试剂检测试管血和导管血S/CO的差异性。方法厦门新创HBs Ag ELISA试剂检测2015年1月1日至2015年4月30日无偿献血者标本17967例,对初次反应性标本用原试管和血袋导管血分别进行双孔复试。结果检测17967例标本,共检测阳性标本143例,阳性率为0.8%。试管血与导管血S/CO≥28有56例,10≤S/CO<28间的有40例,1.5≤S/CO<10的有36例,0.8≤S/CO<1.5的有11例。采用T检验,10≤S/CO<28间的40例和1.5≤S/CO<10的36例,0.8≤S/CO<1.5的11例,导管血S/CO均明显低于试管血。结论除强阳性标本外,导管血S/CO明显低于试管血,为保证血液结果的准确性,对初次反应性处于灰区的标本不适于单独使用导管血进行复查。
文摘本文报道49例Hb G Coushatta在我国西北部的分布情况。新疆和甘肃的发生率为0.57‰和0.43‰,高于陕西的发生率0.07‰。维吾尔、哈萨克、柯尔克孜和回族的发生率为0.66‰—1.74‰,高于汉族的发生率0.45‰。Hb G Coushatta基因流呈由北向南和向西漂移和特点,结合国内外有关资料进行分析,这种变异体起源于东北亚地区,为古代游牧民族的遗传标志。
