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A Review of Chinese Herb Medicine Additives on Chicken Growth Performance 被引量:1
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作者 Cui YANG Yuying LIAO +2 位作者 Fulin WANG Jiahuang YANG Zhuyue WU 《Agricultural Biotechnology》 CAS 2019年第6期48-51,共4页
Researches showed that many Chinese herb medicines can improve chicken growth performance not only by their pharmacological function, but also by the improvement of antioxidant function, immunity and disease resistanc... Researches showed that many Chinese herb medicines can improve chicken growth performance not only by their pharmacological function, but also by the improvement of antioxidant function, immunity and disease resistance of chicken. The menace to human health and environment has occurred since too much antibiotics have been used as growth-promoting additives in long term in chicken industry. Therefore, research on replacement of antibiotics by Chinese herb medicines as additives for chicken growth is underway. This paper summarized some research results in the topic briefly to provide information for researchers and readers. 展开更多
关键词 CHICKEN Chinese herb medicine additive Growth performance Antioxidant function IMMUNITY
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Quality Standard of Yi Herb Medicine Millettia dielsiana
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作者 Maliniu SHA Wenbing LI +4 位作者 Dongmei SHA Meiyi TONG Jing WANG Xinjia YAN Yuan LIU 《Medicinal Plant》 CAS 2022年第5期26-30,共5页
[Objectives]The paper was to establish the quality standard of Yi herb medicine Millettia dielsiana.[Methods]Yi herb medicine M.dielsiana was qualitatively identified by microscopic identification and thin layer ident... [Objectives]The paper was to establish the quality standard of Yi herb medicine Millettia dielsiana.[Methods]Yi herb medicine M.dielsiana was qualitatively identified by microscopic identification and thin layer identification.The content of total isoflavones was determined by UV-Vis spectrophotometry,and the contents of moisture,total ash,acid-insoluble ash and extract were checked according to the method introduced in Chinese Pharmacopoeia(2020 edition).[Results]The microscopic identification features,including stone cells,fiber bundles,calcium oxalate square crystals,starch granules,pigment blocks,ducts,etc.,were distinct.A TLC method for identification of M.dielsiana was established.The contents of water,total ash,acid-insoluble ash and extract should be no more than 13%,no more than 7%,no more than 0.5%and no less than 6%in 10 batches of samples,respectively.The total isoflavones of M.dielsiana based on genistein(C_(15)H_(10)O_(5)) should be no less than 0.25%.The linear relationship of genistein was good in the range of 0.002-0.007 mg/mL(R^(2)=0.9996);the average recovery was 97.01%and the RSD was 2.62%.[Conclusions]The method is simple,accurate and well-reproducible,and can be used for the quality control of Yi herb medicine M.dielsiana. 展开更多
关键词 Yi herb medicine Millettia dielsiana GENISTEIN TLC UV-Vis spectrophotometry
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Study on the Medication Rules of Traditional Chinese Medicine Prescriptions for the Treatment of New Crown Pneumonia Based on Data Mining Technology
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作者 Ya CHEN Xiangling QU +3 位作者 Yuling LUO Yuanfeng YANG Yongming CHEN Yongyue GAO 《Agricultural Biotechnology》 2024年第5期55-62,共8页
[Objectives]This study was conducted to analyze the medication rules of clinical prescriptions of traditional Chinese medicine decoction pieces for the treatment of novel coronavirus pneumonia(COVID-19)during the epid... [Objectives]This study was conducted to analyze the medication rules of clinical prescriptions of traditional Chinese medicine decoction pieces for the treatment of novel coronavirus pneumonia(COVID-19)during the epidemic in multiple regions based on data mining technology,so as to provide a reference for the treatment of COVID-19 with traditional Chinese medicine.[Methods]The traditional Chinese medicine prescriptions used since the outbreak of COVID-19 in Hubei Province during the fight against the epidemic from February 25,2020 to February 14,2022,the traditional Chinese medicine prescriptions used by Guizhou traditional Chinese medicine expert team aiding Hubei Province,the traditional Chinese medicine prescriptions for rehabilitation and conditioning of patients in Ezhou of Hubei Province after discharge,the traditional Chinese medicine prescriptions for the prevention and treatment of COVID-19 in Guizhou Province,and the traditional Chinese medicine prescriptions for the treatment of COVID-19 collected from the end of 2019 to the present from the Chinese database of CNKI were collected as the data of this study.Excel was used to establish a database and enter it into the TCM inheritance calculation platform V3.5,and the association rules and k-means clustering algorithm were used to analyze the frequency of herbal medicines in prescriptions during the treatment of COVID-19,the frequency of four natures,five flavors,meridian distribution,and drug combinations.[Results]A total of 1859 COVID-19 patients treated with traditional Chinese medicine were included,and the proportion of males was higher than that of females,and middle-aged and elderly people were the most common group.A total of 2170 prescriptions of traditional Chinese medicine were included,involving a total of 383 traditional Chinese medicines.High-frequency medicines included poria,Radix Bupleuri,Radix Scutellariae,Herba Pogostemonis,Fructus Forsythiae,Flos Loniceraeetc.The four natures were mainly concentrated in cold,warm and neutral,and the five flavors were mainly concentrated in bitter,pungent and sweet.The herbal medicines were mainly attributed to the lungs and stomach meridians,and were mainly of heat-clearing,exterior syndrome-relieving and diuresis-promoting and damp-clearing types.A total of 24 high-frequency herbal combinations and 35 association rule were excavated,and 3 types of formulas were obtained by cluster analysis.[Conclusions]The analysis results and medicine combinations obtained in the formulas are consistent with the traditional Chinese medicine treatment theory of COVID-19 caused by wind-heat filth accompanied with damp and toxin. 展开更多
关键词 Medicinal herb Medication rule COVID Association rule Cluster analysis
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Effects of Integrated Chinese Herbs and Western Medicine on Swine Toxoplasmosis
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作者 崔平 方素芳 +2 位作者 袁亚丽 顾小龙 郭兵 《Animal Husbandry and Feed Science》 CAS 2009年第2期39-42,共4页
[ Objective] To evaluate the efficacy of integrated Chinese herbs and western medicine on the treatment of swine toxoplasmosis, in order to increase cure rate and lower recurrence rate. [ Method] Pigs artificially inf... [ Objective] To evaluate the efficacy of integrated Chinese herbs and western medicine on the treatment of swine toxoplasmosis, in order to increase cure rate and lower recurrence rate. [ Method] Pigs artificially infected by Toxoplasma gondii were treated with compound suffonamide and a self-designed Chinese herbs formula, and the quantities of toxoplasma in ascites were determined. Animal regression experiment was per- formed after mice were inoculated with pathological samples of the pigs infected with toxoplasma. After treatment with integrated Chinese herbs and western medicine, the clinical manifestations of pigs were observed and the level of circulating antigen (CAg) in sera was detected. Curative effect indexes of integrated Chinese herbs and western medicine-treated group were compared with that of Chinese herbs-treated group, western medi- cine-treated group and positive control group. [ Result] All the toxoplasma trophozoites were killed by integrated and westem medicine. Regression expedment results showed that toxoplasma appeared only in one mouse that was inoculated with brain of pig. The treated pigs had nonsignificant clinical symptoms; the peak of serum CAg was lower than that of the positive control group and CAg turned negative faster than that of Chinese herbs-treated group, westem medicine-treated group, and positive control group. [ Conclusion] The integrated Chinese herbs and western medicine has good effect on the treatment of swine toxoplasmosis. 展开更多
关键词 SWINE TOXOPLASMOSIS Treatment with integrated Chinese herbs and western medicine
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Research on Anti-bacterial Effects of 5 Kinds of Chinese Herb Extracts on Ameromonas hydrophila in vitro 被引量:8
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作者 姜巨峰 王玉佩 李春艳 《Agricultural Science & Technology》 CAS 2010年第8期145-148,共4页
[Objective] The aim was to study the anti-bacterial effects of 5 kinds of Chinese herb extracts on Ameromonas hydrophila in vitro. [Method] in vitro anti-bacterial effects of 5 kinds of Chinese herb extracts like Gall... [Objective] The aim was to study the anti-bacterial effects of 5 kinds of Chinese herb extracts on Ameromonas hydrophila in vitro. [Method] in vitro anti-bacterial effects of 5 kinds of Chinese herb extracts like Galla Chinensis,Syzygium aromaticum,Salvia miltiorrhiza,Punica granatum L. and Terminalia chebula Retz on Ameromonas hydrophila were studied; furthermore,cure rates of the Chinese herb extracts with better anti-bacterial effects were determined to find out the optimal drug dosage. [Result] Under the same experimental conditions,Galla Chinensis,Punica granatum and Terminalia chebula Retz had relatively strong anti-bacterial effects on Ameromonas hydrophila,among them the anti-bacterial effect of Galla Chinensis was significantly higher than those of the others (P0.05). The optimal treatment dose of Galla Chinensis treating bacterial septicemia caused by Aeromonas hydrophila was that they were treated with medicated bath for 40 min by 0.5 mg/ml Galla Chinensis extract,and the cure rate was 100%. [Conclusion] The research provides a scientific drug basis for the control and prevention of outbreak bacterial diseases of fish. 展开更多
关键词 Chinese medicinal herb Galla Chinensis Ameromonas hydrophila Anti-bacterial effect Cure rate
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Advances in treatment of ulcerative colitis with herbs: From bench to bedside 被引量:21
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作者 Ping Wan Hao Chen +1 位作者 Yuan Guo Ai-Ping Bai 《World Journal of Gastroenterology》 SCIE CAS 2014年第39期14099-14104,共6页
Ulcerative colitis(UC), an idiopathic inflammatory disorder in the colon, has become a clinical challenge, owing to the increasing incidence and poor prognosis. The conventional treatments for UC including aminosalicy... Ulcerative colitis(UC), an idiopathic inflammatory disorder in the colon, has become a clinical challenge, owing to the increasing incidence and poor prognosis. The conventional treatments for UC including aminosalicylates, corticosteroids, and immunosuppressants, induce remission in only half of patients. Meanwhile, the treatments often come with serious side effects which can be life-threatening. Herbal medicine, one of the most common traditional Chinese medicine modalities, has been introduced for centuries into clinical treatment of many human diseases such as infections and functional disorders. Recently, the potential effectiveness of herbs has been suggested as the treatment of UC, as shown by a variety of clinical trials and experimental studies. The herbs reported in the literature include aloe vera gel, butyrate, tormentil extracts, wheat grass juice, and curcumin. In the review, bioactivity of the herbs and their involvement in UC treatment are discussed. 展开更多
关键词 Inflammatory bowel disease herbS herb medicine Ulcerative colitis Therapy Safety
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Overview of the phytomedicine approaches against Helicobacter pylori 被引量:13
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作者 Filipa F Vale Monica Oleastro 《World Journal of Gastroenterology》 SCIE CAS 2014年第19期5594-5609,共16页
Helicobacter pylori(H.pylori)successfully colonizes thehuman stomach of the majority of the human popula-tion.This infection always causes chronic gastritis,butmay evolve to serious outcomes,such as peptic ulcer,gastr... Helicobacter pylori(H.pylori)successfully colonizes thehuman stomach of the majority of the human popula-tion.This infection always causes chronic gastritis,butmay evolve to serious outcomes,such as peptic ulcer,gastric carcinoma or mucosa-associated lymphoid tis-sue lymphoma.H.pylori first line therapy recommend-ed by the Maastricht-4 Consensus Report comprises theuse of two antibiotics and a proton-pomp inhibitor,butin some regions failure associated with this treatmentis already undesirable high.Indeed,treatment failure isone of the major problems associated with H.pylori in-fection and is mainly associated with bacterial antibioticresistance.In order to counteract this situation,someeffort has been allocated during the last years in theinvestigation of therapeutic alternatives beyond antibi-otics.These include vaccines,probiotics,photodynamic inactivation and phage therapy,which are briefly revis-ited in this review.A particular focus on phytomedicine,also described as herbal therapy and botanical therapy,which consists in the use of plant extracts for medicinal purposes,is specifically addressed,namely considering its history,category of performed studies,tested com-pounds,active principle and mode of action.The herbs already experienced are highly diverse and usually selected from products with a long history of employ-ment against diseases associated with H.pylori infec-tion from each country own folk medicine.The studies demonstrated that many phytomedicine products have an anti-H.pylori activity and gastroprotective action.Al-though the mechanism of action is far from being com-pletely understood,current knowledge correlates the beneficial action of herbs with inhibition of essential H.pylori enzymes,modulation of the host immune system and with attenuation of inflammation. 展开更多
关键词 Helicobacter pylori Alternative treatment PHYTOmedicine herbal medicine PHYTOTHERAPY Botanical therapy herb medicine PROBIOTICS Antibiotic resistance
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Spectrum-Effect Relationship Between High Performance Liquid Chromatography Fingerprints and Anticoccidial Activities of a Compound Chinese Medicine 被引量:5
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作者 XIAO Sui FEI Chen-zhong +3 位作者 ZHANG Li-fang ZHENG Wen-li ZHANG Ke-yu XUE Fei-qun 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2014年第5期1082-1089,共8页
Quality control and screening of active substances in traditional Chinese medicines have been performed using fingerprint analysis. The spectrum-effect relationship between chromatography fingerprints and efficacy of ... Quality control and screening of active substances in traditional Chinese medicines have been performed using fingerprint analysis. The spectrum-effect relationship between chromatography fingerprints and efficacy of herbal drugs is considered as a potentially useful method for determining active ingredients in complex mixtures. The study was designed to develop a method for determining the bioactive components of a compound Chinese medicine called Tiefeng based on spectrum-effect relationships between high-performance liquid chromatography (HPLC) fingerprints and anticoccidial activities. Four peaks of the established HPLC fingerprint indicate the main bioactive components of this medicine. In addition, pharrnacodynamic atlas was defined and used to assess the anticoccidial activity of Tiefeng from different sources for the first time. We found that the level of anticoccidial activity of Tiefeng was consistent with the degree of similarity between the pharmacodynamic atlas and chromatogram of any sample. Furthermore, effect of this medicine was related with the main active constituents, along with the origin and the harvesting time. 展开更多
关键词 herb medicine FINGERPRINT anticoccidial index spectrum-effect relationship
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Preliminary Study of 12 Chinese Herbs as Feed Attractants on Turbot Juvenile(Scophthalmus maximus)
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作者 朱国霞 白东清 +3 位作者 李玉华 马静 吴旋 宁博 《Agricultural Science & Technology》 CAS 2010年第6期115-116,120,共3页
[Objective] The paper aims to study the attractive effects of 12 Chinese medicinal herbs on Scophthalmus maximus juvenile.[Method] We took 200 Scophthalmus maximus with the average body length of 3 cm,average weight o... [Objective] The paper aims to study the attractive effects of 12 Chinese medicinal herbs on Scophthalmus maximus juvenile.[Method] We took 200 Scophthalmus maximus with the average body length of 3 cm,average weight of 1 g and 60 days of age as the research object,and 12 Chinese medicinal herbs as feed attractants were selected,including Cloves,Cinnamon,Star anise,Kaempferol,Mint,Coptis,Phellodendron,skullcap,Gardenia,Sophora flavescens,Mume,Myrobalan meat were selected.The amount added to the basic diet was 2‰..The times of turbot juveniles going into each inducing room and the times of turbot juveniles biting the feed ball were recorded by maze experiments.Inducing effects of the Chinese herbal medicines were analyzed.[Result] The results showed that the attractant effect of Mume,Gardenia,Scutellaria and kaempferol had the significantly inducing effect on Scophthalmus maximus juvenile.And 2‰ Gardenia,5‰ Matrine,5‰ Scutellaria and 2‰ Kaempferol have the best attractant effects.In compound experients,the attractive effect of mixture of 2‰ matrine and gardenia on Scophthalmus maximus was the best.[Conclusion] The attractive effect on Scophthalmus maximus has something to do with the kind and concentration of Chinese medicinal herbs. 展开更多
关键词 Chinese medicinal herbs Scophthalmus maximus juvenile ATTRACTANT
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Effects of Nourishing “Yin”-Removing “Fire” Chinese Herb Mixture on the Expression of GABAB Receptors in Hypothalamus of Precocious Puberty Female Rats
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作者 Zhejun Chen Zehui Meng +2 位作者 Shiran Wang Liting Zhu Zhanzhuang Tian 《Chinese Medicine》 2016年第2期55-66,共12页
Objectives: To investigate the potential role of GABAB Receptors (GABABRs) involved in the effect of Nourishing “Yin”-Removing “Fire” Chinese herb mixture (TCM) treatment on precocious puberty. Methods: Female Spr... Objectives: To investigate the potential role of GABAB Receptors (GABABRs) involved in the effect of Nourishing “Yin”-Removing “Fire” Chinese herb mixture (TCM) treatment on precocious puberty. Methods: Female Sprague-Dawley rats were randomly divided into four groups: normal (N), central precocious puberty (CPP) model (M), CPP fed with normal saline (S) and CPP fed with Nourishing “Yin”-Removing “Fire” Chinese herb mixture (TCM). Rats of postnatal day 5 were given a single subcutaneous injection of 240 μg danazol to establish CPP model rats. Rats of S and TCM groups were continuously administered with saline or nourishing “Yin”-removing “Fire” Chinese herb mixture since postnatal day 15. The expression of GABABRs was detected by means of real-time PCR and immunohistochemistry. Results: The expression of hypothalamic GnRH mRNA in M was significantly increased on the day of pre-puberty when compared with that of N (P < 0.01). On the day of onset-puberty, LH levels were higher in M than those in N (P < 0.01), while the serum E2 and LH levels of TCM decreased when compared with those of M (P <sub>B1</sub> receptor (GABABR1) immunoreactive cells in the arcuate nucleus (ARN) was decreased in M when compared with that of N (P < 0.05) and increased in TCM compared with that of M (P < 0.05);simultaneously, the expression of GABABR1 mRNA in hypothalamus was significantly decreased in M when compared with that of N (P < 0.01) and increased in TCM compared with that of M (P < 0.01). On the day of onset-puberty, the number of GABABR1 immunoreactive cells in medial septum (MS) was decreased in M compared with that in N (P < 0.05) and increased in TCM comparing with that of M (P < 0.05);meanwhile, the mRNA expression of GABABR1 in hypothalamus was decreased in M compared with that in N (P <sub>B2</sub> receptor (GABABR2) immunoreactive cells in the ARN, MS and diagnonal band of broca (DBB) were decreased in M when compared with those of N (P < 0.05) and increased in TCM compared with those of M (P < 0.05) on the day of onset-puberty. At the same time, the mRNA expression of GABABR2 was significantly decreased in M compared with that of N (P < 0.01). Conclusions: These results indicated that the GABABRs might involve in the curative effect of Nourishing “Yin”-Removing “Fire” Chinese herbal mixture on CPP rats. 展开更多
关键词 Precocious Puberty GABAB Receptors Chinese herb medicine DANAZOL RATS
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Determination of vanadium in food and traditional Chinese medicine by graphite furnace atomic absorption spectroscopy 被引量:3
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作者 ZOUMingqiang JIANGTiansu +1 位作者 WANGDaning ZHAIQingzhou 《Rare Metals》 SCIE EI CAS CSCD 2003年第1期14-18,共5页
Various experimental conditions were described for the vanadium determinationby graphite furnace atomic absorption spectroscopy (GFAAS). The experiments showed that whenatomization took place under the conditions wher... Various experimental conditions were described for the vanadium determinationby graphite furnace atomic absorption spectroscopy (GFAAS). The experiments showed that whenatomization took place under the conditions where the combination of a pyrolytic coating graphitetube and fast raising temperature were used and the temperature was stable, the signal peak shapescould be improved, the sensitivity was enhanced, and the memory effect was removed. The vanadium infood and traditional Chinese medicinal herbs can be accurately determined using the standard curvemethod. 展开更多
关键词 vanadium determination graphite furnace atomic absorption spectroscopy(GFAAS) FOOD traditional Chinese medicinal herb
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Clinical trial of Butea superba, an alternative herbal treatmentfor erectile dysfunction 被引量:2
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作者 W.Cherdshewasart N.Nimsakul 《Asian Journal of Andrology》 SCIE CAS CSCD 2003年第3期243-246,共4页
Aim: To study the effect of Butea superba on erectile dysfunction (ED) in Thai males. Methods: A 3-month randomized double-blind clinical trial was carried out in volunteers with ED, aged 30 years ~ 70 years, to evalu... Aim: To study the effect of Butea superba on erectile dysfunction (ED) in Thai males. Methods: A 3-month randomized double-blind clinical trial was carried out in volunteers with ED, aged 30 years ~ 70 years, to evaluate the therapeutic effect of the crude preparation of Butea superba tubers on ED. Results: There was a significant upgrading in 4 of the 5 descriptive evaluations of the IIEF-5 questionnaire. Estimation of the sexual record indicated that 82.4 % of the patients exhibited noticeable improvement. Haematology and blood chemistry analysis revealed no apparent change. Conclusion: The plant preparation appears to improve the erectile function in ED patients without apparent toxicity. 展开更多
关键词 Butea superba erectile dysfunction phytoandrogen medicinal herb
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Antioxidant activity and hepatoprotective effect of 10 medicinal herbs on CCl4-induced liver injury in mice 被引量:3
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作者 Xiao Meng Guo-Yi Tang +3 位作者 Pin-He Liu Chan-Juan Zhao Qing Liu Hua-Bin Li 《World Journal of Gastroenterology》 SCIE CAS 2020年第37期5629-5645,共17页
BACKGROUND Many natural products confer health benefits against diverse diseases through their antioxidant activities.Carbon tetrachloride(CCl4)is often used in animal experiments to study the effects of substances on... BACKGROUND Many natural products confer health benefits against diverse diseases through their antioxidant activities.Carbon tetrachloride(CCl4)is often used in animal experiments to study the effects of substances on liver injury and the related mechanisms of action,among which oxidative stress is a major pathogenic factor.AIM To compare antioxidant and hepatoprotective activities of ten herbs and identify and quantify phytochemicals for the one with strongest hepatoprotection.METHODS The antioxidant activity of ten medicinal herbs was determined by both ferricreducing antioxidant power and Trolox equivalent antioxidant capacity assays.The total phenolic and flavonoid contents were determined by Folin–Ciocalteu method and aluminum chloride colorimetry,respectively.Their effects on CCl4-induced oxidative liver injury were evaluated and compared in a mouse model by administrating each water extract(0.15 g/mL,10 mL/kg)once per day for seven consecutive days and a dose of CCl4 solution in olive oil(8%,v/v,10 mL/kg).The herb with the strongest hepatoprotective performance was analyzed for the detailed bioactive components by using high-performance liquid chromatography-electrospray ionization source-ion trap tandem mass spectrometry.RESULTS The results revealed that all tested herbs attenuated CCl4-induced oxidative liver injury;each resulted in significant decreases in levels of serum alanine transaminase,aspartate transaminase,alkaline phosphatase,and triacylglycerols.In addition,most herbs restored hepatic superoxide dismutase and catalase activities,glutathione levels,and reduced malondialdehyde levels.Sanguisorba officinalis(S.officinalis)L.,Coptis chinensis Franch.,and Pueraria lobata(Willd.)Ohwi root were the three most effective herbs,and S.officinalis L.exhibited the strongest hepatoprotective effect.Nine active components were identified in S.officinalis L.Gallic acid and(+)-catechin were quantified(7.86±0.45 mg/g and 8.19±0.57 mg/g dried weight,respectively).Furthermore,the tested herbs displayed a range of in vitro antioxidant activities proportional to their phenolic content;the strongest activities were also found for S.officinalis L.CONCLUSION This study is of value to assist the selection of more effective natural products for direct consumption and the development of nutraceuticals or therapeutics to manage oxidative stress-related diseases. 展开更多
关键词 Antioxidant activity CCl4-induced liver injury Medicinal herbs HEPATOPROTECTION Sanguisorba officinalis L. Coptis chinensis Franch
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Screening the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34^(cdc2) kinase 被引量:2
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作者 杨骅 郑树 +5 位作者 MEIJER Laurent 李士敏 LECLERC Sophie 郁琳琳 程金泉 张苏展 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE EI CAS CSCD 2005年第7期656-663,共8页
Objective: To screen and evaluate the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25phosphatase. Methods: The affinity chromatography purified glutashione-S-transferase/Cdc25A phosphatase... Objective: To screen and evaluate the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25phosphatase. Methods: The affinity chromatography purified glutashione-S-transferase/Cdc25A phosphatase fusion protein and Cdc2/cyclin B from the extracts of starfish M phase oocytes are used as the cell cycle-specific targets for screening the antimitotic constituents. We tested 9 extracts isolated from the Chinese medicinal herbs and vegetables including the agents currently used in cancer treatment by measuring the inhibition of Cdc25A phosphatase and Cdc2 kinase activity. The antitumor activity of the extracts was also evaluated by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and flow cytometry.Results: Cdc25A inhibitory activity and antitumor activity are detected in the extracts isolated from three Chinese medicinal herbs Agrimonapilosa; Herba solani lyrati; Galla chinesis. Conclusion: We found three extracts isolated from Chinese medicinal herbs have potential inhibitory activity of Cdc25 phosphatase using a highly specific mechanism-based screen assay for antimitotic drug discovery. 展开更多
关键词 Chinese medicinal herbs Cdc25 phosphatase inhibition Cell cycle Anti-tumor activity
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Screening of Epstein-Barr Virus Early Antigen Expression Inducers from Chinese Medicinal Herbs and Plants 被引量:3
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作者 ZENG YI ZHONG JI +4 位作者 AN-MING YE SHU-QING NI ZHI-Yu MIAO XUL-QIAN MO YONU-KUN AND LI ZE-LIN(Institute of Virology, Chinese Academy ’ of ’Preventive Medicine, Beijing,)(Nasopharyngeal Control and Treatmenl Institute of Cangwu, Guangxi,Guangxi Herbs Bitany 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 1994年第1期50-55,共6页
Ether extrilcls of 1693 Chinesc medicinal herbs and plilnts from 268 families werestudied for the induction of Epstcin-Barr viral (EBV ) early antigcn (EA ) expression in theRaji cell line. Fifty-two from 18 families ... Ether extrilcls of 1693 Chinesc medicinal herbs and plilnts from 268 families werestudied for the induction of Epstcin-Barr viral (EBV ) early antigcn (EA ) expression in theRaji cell line. Fifty-two from 18 families were found to have inducing activity. Twenty-fiveand seven of them were from Euphorbiaccae and Thymclaeaceae, respectively. Some ofthem, such as Croton tiglium, Euphorbia kansui, Daphnc genkwa, Wikstrocmia chamacdaphen, Wikstroemia indica, Prunus mandshurica Koehne and Achyranthes bidentata arecommonly used drugs. The significance of these herbs in the activation of EBV in vivo andtheir relation to the development of nasopharyngeal carcinoma were discussed. 展开更多
关键词 In Screening of Epstein-Barr Virus Early Antigen Expression Inducers from Chinese Medicinal herbs and Plants Raji
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The Influence of Chinese Medicinal Herb on Chicken Immune Organs and Small Intestinal Mucosa Immune Organization 被引量:2
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作者 GAO Gui-sheng SHI Qiu-mei +2 位作者 ZHANG Yan-ying SHEN Ping TANG Sheng-ling 《Animal Husbandry and Feed Science》 CAS 2012年第5期212-215,共4页
[Objective] The aim was to explore the mechanism of Chinese medicinal herb to enhance the body's immune. [Method] The quantitative distribution of immunocytes in chicken small intestinal mucosa lymphoid tissue-secret... [Objective] The aim was to explore the mechanism of Chinese medicinal herb to enhance the body's immune. [Method] The quantitative distribution of immunocytes in chicken small intestinal mucosa lymphoid tissue-secretory type immune globulin cell A were dynamic observed to research chicken immune organ growth with histology conventional slice technology and immunohistochemistry dye. 1 day age healthy roosters were divided into 3 groups: the group 3 was control group. 1% and 0.5% concentration of Chinese herbal medicine immunopotentiator drinking water were added in the group 1 and 2 in continuous 60 d. The immune organ index was determined every 12 d and the histotomy of chicken small intes- tine in group control and 1% were taken for histological observation on day 24, 36 and 48. [ Result] Treatment group immune organ index was significantly higher than that of the control group and 1% group of small intestinal villus inherent intraformational immune cells number significantly increased (P〈0.01) compared with controls. Day 36 age group and day 48 group immune cells were higher than day 24 group of cell number (P〈 0.01 ). [ Conclusionl Chinese medicinal herb had obvious role in promoting chicken immune organ growth and obvious influence on the quantity change of the intestinal mucosal immune cells. 展开更多
关键词 Chinese medicinal herb Immune organs The small intestinal mucosa immune cells IMMUNOHISTOCHEMISTRY
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Effect of Ploughing Depth on the Growth and Yield of Heracleum candicans:a Threatened Medicinal Herb and a Less-explored Potential Crop of the Himalayan Region 被引量:1
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作者 Hemant K. Badola Jitendra S. Butola 《Journal of Mountain Science》 SCIE CSCD 2005年第2期173-180,共8页
This paper examines the effect of ploughing depths (A -- 60 cm, B -- 45 cm and C -- 30 cm) on the growth and yield of Heracleum candicans Wall (Apiaceae), a threatened medicinal herb of the Himalayan region. This ... This paper examines the effect of ploughing depths (A -- 60 cm, B -- 45 cm and C -- 30 cm) on the growth and yield of Heracleum candicans Wall (Apiaceae), a threatened medicinal herb of the Himalayan region. This less-explored plant is being suggested as a potential crop for the mountain agriculture. The study was carried out in an orchard in Himachal Pradesh, India at 2500 m altitude, for two successive growth years. During the first year, all plants remained in juvenile state; in the second year, nearly 65 % plants produced flowers only under 60cm ploughing depth. Among its morphological traits, plant height, collar diameter and aboveground flesh weight were found to be strongly correlated (P 〈 0.01) with the belowground biomass during the first year (r =0.968, 0.925 and 0.973, respectively) and during the second year (r=0.945, 0.928 and 0.775, respectively). Increase in the ploughing depth was significantly correlated (P〈0.01) with all growth parameters, including the belowground dry weight, marketable portion of the produce. The belowground biomass (commercial yield; 16.28 Qt/hec) at depth A was about 2.6 and 4.7 times higher than those recorded at depths B and C, respectively. The results clearly justify the importance of deep ploughing and this paper strongly recommends it for economically sustainable cropping. 展开更多
关键词 CROP Heracleum candicans medicinal herb morphological traits ploughing depth yield mountain agriculture Patrala
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Effects of the Chinese Medicinal Herb Com plex Additives on Non-specific Immunity of Amursturgeon( Acipenser schrencki Brandt) 被引量:1
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作者 Wang Di Liu Hongbai 《Animal Husbandry and Feed Science》 CAS 2014年第3期123-126,130,共5页
This study was to investigate the effects of aqueous decotion from three Chinese medicinal herb additives ( Cyrtomium fortunei, prescription I and prescription II) on non-specific immunity of 1 + age old Amur sturg... This study was to investigate the effects of aqueous decotion from three Chinese medicinal herb additives ( Cyrtomium fortunei, prescription I and prescription II) on non-specific immunity of 1 + age old Amur sturgeon (Acipenser schrencki Brandt) by oral perfusion. Cyrtomiumfortunei, prescription I and prescription II were orally given to 15 fishes for each experimental group once a day, with the concentration of 9,175 and 36 g/S0 kg body weight, respectively. The administration was lasted for 14 days. Meanwhile, distilled water was orally given as the control. After the experiment, some of the experimental fishes were stimulated with high temperature (30 ℃ ) for two hours. Sampling was performed from fishes treated at 22 ℃ and 30 ℃ for measuring the protein content in the serum, phagocytic activity of leucocytes and the activity of the lysozyme in six tissues. The results indicated that Cyrtomiumfortunei and prescription II could help to enhance the content of various proteins and the phagocytic activity of leucocytes. There was no significant change in the effects between these two additives at either the normal temperature or high temperature. Prescription I did not show an obvious effect on the immunity of fishes at the normal temperature, but it did in promo- ting high-efficiency response and improving immunoregulation of fish shocked by some stimuli. 展开更多
关键词 Chinese medicinal herb Amur sturgeon Non-specific immunity Effect
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Effect of contrasting climates on antioxidant and bioactive constituents in five medicinal herbs in Western Himalayas 被引量:1
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作者 Tarandeep KAUR Rohini BHAT Dhiraj VYAS 《Journal of Mountain Science》 SCIE CSCD 2016年第3期484-492,共9页
To understand the effect of climate change on constitutive antioxidant and biochemical metabolites in Western Himalayas, five medicinal herbs were selected and grown at two altitudes in Jammu(305 m) and Srinagar(1730 ... To understand the effect of climate change on constitutive antioxidant and biochemical metabolites in Western Himalayas, five medicinal herbs were selected and grown at two altitudes in Jammu(305 m) and Srinagar(1730 m) with subtropical and temperate climates, respectively.Significant variations were observed in phenols and flavonoids in Hypericum perforatum L., Matricaria chamomilla L., Thymus vulgaris L., Cynara cardunculus L. and Echinacea purpurea L. growing at two locations. High altitude temperate site show variable(up to 13 fold) increase in their content.Proteins(1.3- 1.8 times), sugars(2.8- 4.1 times) and free amino acid(1.04- 1.22 times) were also higher at Srinagar(1730 m). Within these plants, H.perforatum and M. chamomilla have shown higher accumulation of phenols, xanthophylls and proline even at subtropical environment in Jammu(305 m)suggesting potential for increasing their geographical area. The results demonstrate that changing environmental conditions significantly affect the bioactive constituents, which accumulate as a defence strategy by these temperate plants. Their medicinal significance during climate change scenario has also been discussed. 展开更多
关键词 Medicinal herbs Flavonoids Phenols Glutathione Western Himalayas Climate change
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Evaluation of Insecticidal Properties of Some Medicinal Herbs on the Confused Flour Beetle Tribolium confusum (Tenebrionidae: Coleoptera)
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作者 Osama Saeed Mohammad 《Journal of Agricultural Science and Technology(B)》 2012年第1期99-106,共8页
Five concentrations effects of nine herb powders against the confused flour beetle T. confusum have been studied under controlled conditions. The insecticidal effects of using powders on the egg, larval, pupal and adu... Five concentrations effects of nine herb powders against the confused flour beetle T. confusum have been studied under controlled conditions. The insecticidal effects of using powders on the egg, larval, pupal and adult stages of the insect showed that some of which (e.g., Foeniculum capillaceum and Anethum graveolens) have certain effects on the different stages of the studied insect even at the lowest concentrations. The mentioned herb powders showed very high mortality for egg stage reached 96.6% and 93.3% respectively at the lowest concentration and 100% at the highest concentration for both powders. Other powdered herbs showed prolonged effect of durations for larval stage. For example, Acorus calamus prolonged this duration to 34.2 days, at the first concentration while it was 25.4 days for control treatment. At the second concentration it was 53 and 41.5 days for An. gr. and Pimpinella anisum respectively, also Matricaria chamomilla showed similar effect at the 4th and 5th concentrations. Comparing with high numbers of progeny for the control treatment, also some powdered herbs showed high effect on respiration of the adults. The quantity of oxygen consumed by untreated beetles during the time of experiment (90 min) was so high than that of beetles treated with Ac. caL, Artemisia absinthium and AL sat. Moreover the internal systems of both sex males and females have been affected, ducts showing different changes when studied anatomically giving small size of ovarioles, deformed of accessory glands, swollen of stink glands with liquid oil. Majority of those males showed small testis. Most of the mentioned effects were happened as results of the powders of A c. cal., Al. sat., and Ma. ch., also the powders of F. cap., and A. abs., decrease the sizes of the testis, and accessory glands. 展开更多
关键词 Medicinal herbs POWDERS control storage pest.
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