Medicinal synthetic Aluminum-magnesium silicate (MSAMS), which has inhibited Human immune deficiency virus (HIV), in vitro, was used for trial-treatment of HIV/AIDS patients. Their plasma were tested for viral loads (...Medicinal synthetic Aluminum-magnesium silicate (MSAMS), which has inhibited Human immune deficiency virus (HIV), in vitro, was used for trial-treatment of HIV/AIDS patients. Their plasma were tested for viral loads (VL): before and repeatedly during the treatment. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection?. After 4 weeks, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When VL decreased bellow 50/ml, the treatment continued, 4 weeks before stopping. Mean-VL of four patients increased (P = 0.006) from 498.50 ± 33.37 to 1,072.50 ± 184.55, after 3.75±2.06 weeks and decreased (P = 0.040) to 407.33 ± 297.27 (18.29%) when the treatment-duration increased to 6.67 ± 2.31 weeks. Prolonging the duration to 12.00 ± 2.83 weeks led to 98.68% decrease of mean-VL of four other patients, from 24,250.00 ± 15,939.34 to 321.00 ± 229.38(P = 0.045). Two HIV positive persons treated for 4 weeks after their VL reduced bellow 50/ml have remained healthy, 10 and 16 months respectively, without routine antiretroviral medication.展开更多
For clinical trial of Medicinal synthetic Aluminum-magnesium silicate (MSAMS, Antivirt<sup>®</sup>), on viral loads and CD4-lymphocytes counts of HIV/AIDS patients, 10 volunteers were treated. Thei...For clinical trial of Medicinal synthetic Aluminum-magnesium silicate (MSAMS, Antivirt<sup>®</sup>), on viral loads and CD4-lymphocytes counts of HIV/AIDS patients, 10 volunteers were treated. Their blood samples were tested for viral loads and for CD4-lymphocytes counts, before the treatment and every 4 weeks during the medication. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection<sup>®</sup> (1 tablet/day), for 4 weeks. Then, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When their viral loads become undetectable, they would be treated for additional 4 weeks. Initially, the Antivirt<sup>®</sup>-regimen appeared to worsen both HIV infection-load and immune deficiency but later relieved them. Patients’ mean-viral load increased (P = 0.020), from 1820.30 ± 868.75 to 2855.90 ± 960.98, after 4 weeks before reducing (P = 0.030) to 1565.20 ± 743.17, after 8 weeks. Similarly, their mean-CD4-lymphocytes count reduced (P = 0.008) from 496.80 ± 194.39 to 263.90 ± 149.26, after 4 weeks before improving (P = 0.001) to 507.90 ± 133.19, after 8 weeks.展开更多
文摘Medicinal synthetic Aluminum-magnesium silicate (MSAMS), which has inhibited Human immune deficiency virus (HIV), in vitro, was used for trial-treatment of HIV/AIDS patients. Their plasma were tested for viral loads (VL): before and repeatedly during the treatment. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection?. After 4 weeks, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When VL decreased bellow 50/ml, the treatment continued, 4 weeks before stopping. Mean-VL of four patients increased (P = 0.006) from 498.50 ± 33.37 to 1,072.50 ± 184.55, after 3.75±2.06 weeks and decreased (P = 0.040) to 407.33 ± 297.27 (18.29%) when the treatment-duration increased to 6.67 ± 2.31 weeks. Prolonging the duration to 12.00 ± 2.83 weeks led to 98.68% decrease of mean-VL of four other patients, from 24,250.00 ± 15,939.34 to 321.00 ± 229.38(P = 0.045). Two HIV positive persons treated for 4 weeks after their VL reduced bellow 50/ml have remained healthy, 10 and 16 months respectively, without routine antiretroviral medication.
文摘For clinical trial of Medicinal synthetic Aluminum-magnesium silicate (MSAMS, Antivirt<sup>®</sup>), on viral loads and CD4-lymphocytes counts of HIV/AIDS patients, 10 volunteers were treated. Their blood samples were tested for viral loads and for CD4-lymphocytes counts, before the treatment and every 4 weeks during the medication. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection<sup>®</sup> (1 tablet/day), for 4 weeks. Then, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When their viral loads become undetectable, they would be treated for additional 4 weeks. Initially, the Antivirt<sup>®</sup>-regimen appeared to worsen both HIV infection-load and immune deficiency but later relieved them. Patients’ mean-viral load increased (P = 0.020), from 1820.30 ± 868.75 to 2855.90 ± 960.98, after 4 weeks before reducing (P = 0.030) to 1565.20 ± 743.17, after 8 weeks. Similarly, their mean-CD4-lymphocytes count reduced (P = 0.008) from 496.80 ± 194.39 to 263.90 ± 149.26, after 4 weeks before improving (P = 0.001) to 507.90 ± 133.19, after 8 weeks.
