The freestyle Hopkinson bar is a kind of main high g loading equipment utilized widely in calibration of high g accelerometer and other high shock conditions. The calibration experiment of accelerometer was conducted....The freestyle Hopkinson bar is a kind of main high g loading equipment utilized widely in calibration of high g accelerometer and other high shock conditions. The calibration experiment of accelerometer was conducted. With one-dimension stress wave theory, ANSYS/LS-DYNA software and experiment, the effect rules of the projectile＇s front-head style and the accelerometer＇s mounted base＇s length on acceleration waveform were analyzed. The results show that the acceleration duration inspired from Hopkinson bar is almost equal to the rising edge time of perfect half sine stress wave, and it is independent to the mounted base＇s length. Moreover, the projectile＇s fronthead style is a main affecting factor, and the projectiles with less Conical degrees will produce the lower amplitude and longer acceleration duration.展开更多
目的在弹箭发射与侵彻时,弹箭系统内部测试电路元件承受高g值加载。为提高电路元件的存活度,需对其进行缓冲防护。方法利用气炮装置发射钢弹,撞击底座获得高g值加载,研究铝合金薄壁管的抗冲击特性,并基于LS-DYNA研究薄壁管壁厚和冲击速...目的在弹箭发射与侵彻时,弹箭系统内部测试电路元件承受高g值加载。为提高电路元件的存活度,需对其进行缓冲防护。方法利用气炮装置发射钢弹,撞击底座获得高g值加载,研究铝合金薄壁管的抗冲击特性,并基于LS-DYNA研究薄壁管壁厚和冲击速度对高g值冲击过程的影响。结果钢弹冲击速度增加,底座的激励加速度幅值(Acceleration Amplitude of Excitation,AAE)逐渐增加,单层管(CirT)和多胞管(MT)的缓冲效率分别达到91.0%和74.7%,数值模拟所得AAE和响应加速度幅值(Acceleration Amplitude of Response,AAR)与实验结果误差<5%,薄壁管壁厚对激励加速度几乎无影响。结论本文所得结果对轻质元件的高g值冲击防护有较强的指导意义。展开更多
A high-g beam-mass structure accelerometer was designed.In this structure,by means of KOH back etching on the mass,V-groove structure was fabricated on the backside of the mass,so the weight of the mass and also the r...A high-g beam-mass structure accelerometer was designed.In this structure,by means of KOH back etching on the mass,V-groove structure was fabricated on the backside of the mass,so the weight of the mass and also the relative distance between the mass center and the neutral plane were all decreased.With the thin mass structure,we can take advantage of both beam-mass structure and flat film structure;the fabrication process is also simple.By means of Hopkinson shock test system,we did the accelerometer calibration.According to the test result,the sensitivity of the MEMS accelerometer is 0.71 μV/g,which keeps in accordance with the theoretical calculation.After a 200 000 g shocking test,the micro structure worked as usual,so this design can satisfy the requirements of high shock,seriously vibration test environment.展开更多
Background: RNA editing is a co/posttranscriptional modification mechanism that increases the diversity of transcripts, with potential functional consequences. The advent of next-generation sequencing technologies has...Background: RNA editing is a co/posttranscriptional modification mechanism that increases the diversity of transcripts, with potential functional consequences. The advent of next-generation sequencing technologies has enabled the identification of RNA edits at unprecedented throughput and resolution. However, our knowledge of RNA editing in swine is still limited.Results: Here, we utilized RES-Scanner to identify RNA editing sites in the brain, subcutaneous fat, heart, liver,muscle, lung and ovary in three 180-day-old Large White gilts based on matched strand-specific RNA sequencing and whole-genome resequencing datasets. In total, we identified 74863 editing sites, and 92.1% of these sites caused adenosine-to-guanosine(A-to-G) conversion. Most A-to-G sites were located in noncoding regions and generally had low editing levels. In total, 151 A-to-G sites were detected in coding regions(CDS), including 94 sites that could lead to nonsynonymous amino acid changes. We provide further evidence supporting a previous observation that pig transcriptomes are highly editable at PRE-1 elements. The number of A-to-G editing sites ranged from 4155(muscle) to 25001(brain) across the seven tissues. The expression levels of the ADAR enzymes could explain some but not all of this variation across tissues. The functional analysis of the genes with tissuespecific editing sites in each tissue revealed that RNA editing might play important roles in tissue function.Specifically, more pathways showed significant enrichment in the fat and liver than in other tissues, while no pathway was enriched in the muscle.Conclusions: This study identified a total of 74863 nonredundant RNA editing sites in seven tissues and revealed the potential importance of RNA editing in tissue function. Our findings largely extend the porcine editome and enhance our understanding of RNA editing in swine.展开更多
A triaxial high-g accelerometer of microelectro mechanical systems （MEMS） has a struc- ture of multi-chips combination and will be used in aerospace field, civil and military fields. The ac- celerometer can measure ...A triaxial high-g accelerometer of microelectro mechanical systems （MEMS） has a struc- ture of multi-chips combination and will be used in aerospace field, civil and military fields. The ac- celerometer can measure the acceleration of the carrier. The chips with island-membrane structures on its back surfaces are made by MEMS dry processing. The chip is reasonable and can work well under high impact load; Titanium alloy base is also stronger in high shock environment, these are proved by finite element analysis. Finally, the MEMS combined triaxial high-g accelerometer is vali- dated by high impact calibration experiments in order to get a key performance index, including range, sensitivity and transverse sensitivity and so on. These data can satisfy the need of design but some problems remain, these will be eliminated by improvement of the processing technology and materials.展开更多
文摘The freestyle Hopkinson bar is a kind of main high g loading equipment utilized widely in calibration of high g accelerometer and other high shock conditions. The calibration experiment of accelerometer was conducted. With one-dimension stress wave theory, ANSYS/LS-DYNA software and experiment, the effect rules of the projectile＇s front-head style and the accelerometer＇s mounted base＇s length on acceleration waveform were analyzed. The results show that the acceleration duration inspired from Hopkinson bar is almost equal to the rising edge time of perfect half sine stress wave, and it is independent to the mounted base＇s length. Moreover, the projectile＇s fronthead style is a main affecting factor, and the projectiles with less Conical degrees will produce the lower amplitude and longer acceleration duration.
文摘目的在弹箭发射与侵彻时,弹箭系统内部测试电路元件承受高g值加载。为提高电路元件的存活度,需对其进行缓冲防护。方法利用气炮装置发射钢弹,撞击底座获得高g值加载,研究铝合金薄壁管的抗冲击特性,并基于LS-DYNA研究薄壁管壁厚和冲击速度对高g值冲击过程的影响。结果钢弹冲击速度增加,底座的激励加速度幅值(Acceleration Amplitude of Excitation,AAE)逐渐增加,单层管(CirT)和多胞管(MT)的缓冲效率分别达到91.0%和74.7%,数值模拟所得AAE和响应加速度幅值(Acceleration Amplitude of Response,AAR)与实验结果误差<5%,薄壁管壁厚对激励加速度几乎无影响。结论本文所得结果对轻质元件的高g值冲击防护有较强的指导意义。
基金Shanxi province young leaders on science and by program for New Century Excellent Talents in University(NCET)
文摘A high-g beam-mass structure accelerometer was designed.In this structure,by means of KOH back etching on the mass,V-groove structure was fabricated on the backside of the mass,so the weight of the mass and also the relative distance between the mass center and the neutral plane were all decreased.With the thin mass structure,we can take advantage of both beam-mass structure and flat film structure;the fabrication process is also simple.By means of Hopkinson shock test system,we did the accelerometer calibration.According to the test result,the sensitivity of the MEMS accelerometer is 0.71 μV/g,which keeps in accordance with the theoretical calculation.After a 200 000 g shocking test,the micro structure worked as usual,so this design can satisfy the requirements of high shock,seriously vibration test environment.
基金supported by the National Key Technology R&D Program of China(2015BAD03B02–2)Beijing Natural Science Foundation(6174047)+1 种基金earmarked fund for Modern Agro-industry Technology Research System(CARS-35)Agricultural Science and Technology Innovation Program(ASTIP-IAS02)
文摘Background: RNA editing is a co/posttranscriptional modification mechanism that increases the diversity of transcripts, with potential functional consequences. The advent of next-generation sequencing technologies has enabled the identification of RNA edits at unprecedented throughput and resolution. However, our knowledge of RNA editing in swine is still limited.Results: Here, we utilized RES-Scanner to identify RNA editing sites in the brain, subcutaneous fat, heart, liver,muscle, lung and ovary in three 180-day-old Large White gilts based on matched strand-specific RNA sequencing and whole-genome resequencing datasets. In total, we identified 74863 editing sites, and 92.1% of these sites caused adenosine-to-guanosine(A-to-G) conversion. Most A-to-G sites were located in noncoding regions and generally had low editing levels. In total, 151 A-to-G sites were detected in coding regions(CDS), including 94 sites that could lead to nonsynonymous amino acid changes. We provide further evidence supporting a previous observation that pig transcriptomes are highly editable at PRE-1 elements. The number of A-to-G editing sites ranged from 4155(muscle) to 25001(brain) across the seven tissues. The expression levels of the ADAR enzymes could explain some but not all of this variation across tissues. The functional analysis of the genes with tissuespecific editing sites in each tissue revealed that RNA editing might play important roles in tissue function.Specifically, more pathways showed significant enrichment in the fat and liver than in other tissues, while no pathway was enriched in the muscle.Conclusions: This study identified a total of 74863 nonredundant RNA editing sites in seven tissues and revealed the potential importance of RNA editing in tissue function. Our findings largely extend the porcine editome and enhance our understanding of RNA editing in swine.
基金Supported by the National Natural Science Foundation of China(61273346)the National Defense Major Fundamental Research Program of China(20110003)+3 种基金the National Defense Key Fundamental Research Program of China(20132010)Specialized Research Fund for the Doctoral Program of Higher Education(20121101120009)Excellent Young Scholars Research Fund of Beijing Institute of Technology(2012YG0203)the Program for the Fundamental Research of Beijing Institute of Technology(2015CX02034)
文摘A triaxial high-g accelerometer of microelectro mechanical systems （MEMS） has a struc- ture of multi-chips combination and will be used in aerospace field, civil and military fields. The ac- celerometer can measure the acceleration of the carrier. The chips with island-membrane structures on its back surfaces are made by MEMS dry processing. The chip is reasonable and can work well under high impact load; Titanium alloy base is also stronger in high shock environment, these are proved by finite element analysis. Finally, the MEMS combined triaxial high-g accelerometer is vali- dated by high impact calibration experiments in order to get a key performance index, including range, sensitivity and transverse sensitivity and so on. These data can satisfy the need of design but some problems remain, these will be eliminated by improvement of the processing technology and materials.
