This study evaluated the value of high-frequency ultrasonograpy for early detection of dorsal artery of foot in patients with type 2 diabetes mellitus （MD）. Eighty subjects including 40 patients with type 2 MD （T2D...This study evaluated the value of high-frequency ultrasonograpy for early detection of dorsal artery of foot in patients with type 2 diabetes mellitus （MD）. Eighty subjects including 40 patients with type 2 MD （T2DM group） and 40 healthy volunteers （NC group） were recruited. The intima-media thickness （IMT）, the inner diameter and the perfusion of dorsal artery of foot were measured by using high-frequency ultrasonograpy. Meanwhile, the parameters of vascular elasticity, including stiffness parameter （]3）, pressure-strain elastic modulus （Ep）, arterial compliance （AC）, augment index （AI）, and pulse wave conducting velocity （PWV]3） were detected by means of echo-tracking technique. The results showed that no significant difference was found in the IMT, systolic diameter （Ds）, diastolic diameter （Dd） and peak systolic velocity （PSV） between T2DM and NC groups. Ep and PWVβ were increased, and AC was decreased in T2DM group as compared with those in NC group with the differences being significant （P〈0.05 for all）. There was no significant difference in β and AI between T2DM and NC groups. It was concluded that high-frequency ultra- sonography in combination with echo-tracking technique is sensitive and non-invasive, and can be used for early detection of sclerosis of the lower extremity artery in patients with type 2 MD.展开更多
BACKGROUND: It is a globally challenging problem to differentially diagnose biliary atresia (BA) from other disease processes causing infantile cholestatic jaundice. The high frequency ultrasonography (HUS) yields muc...BACKGROUND: It is a globally challenging problem to differentially diagnose biliary atresia (BA) from other disease processes causing infantile cholestatic jaundice. The high frequency ultrasonography (HUS) yields much improved spatial resolution and therefore, might show better image in BA diagnostic examination. The present study was to evaluate the HUS on the diagnosis of BA in infants with jaundice. METHODS: Fifty-one infants with neonatal jaundice were scanned with ultrasonography. Images included gallbladder, bile duct, right hepatic artery (RHA), portal vein (PV) and triangular cord (TC) sign, magnetic resonance imaging and additionally laboratory tests and histopathology reports were assessed. RESULTS: Twenty-three BA and 28 non-BA cases were con firmed. The sensitivity, specificity, and accuracy of HUS were 91.3%, 92.9%, and 92.2%, respectively. All of these indices were significantly higher than those of conventional ultrasonography (P【0.01) and MR cholangiopancreatography (P【0.05). The HUS features, included a positive TC sign, an increased RHA diameter and RHA-diameter to portal-vein-diameter ratio (RHA/PV) and abnormal gallbladder, were important in the diagnosis of BA. CONCLUSION: HUS provided better imaging of BA and should be considered as a primary modality in the differential diagnosis of infantile jaundice.展开更多
目的探讨高频超声造影(CEUS)在浅表肝脏局灶性病变(FLLs)检出及诊断中的临床价值。方法选取我院浅表FLLs患者38例,共63个病变,分别使用低频凸阵探头和高频线阵探头对患者进行CEUS检查,比较低频CEUS与高频CEUS在病变可见度评分、检出率...目的探讨高频超声造影(CEUS)在浅表肝脏局灶性病变(FLLs)检出及诊断中的临床价值。方法选取我院浅表FLLs患者38例,共63个病变,分别使用低频凸阵探头和高频线阵探头对患者进行CEUS检查,比较低频CEUS与高频CEUS在病变可见度评分、检出率和良恶性鉴别诊断中的差异。结果浅表FLLs在高频CEUS下平均可见度评分和检出率分别为(3.62±0.79)分、93.7%(59/63),均显著高于低频CEUS[(2.44±1.04)分、57.1%(36/63)],差异均有统计学意义(均P<0.05)。高频CEUS对最大径≤1 cm FLLs、最大径1~2 cm FLLs和肝转移瘤的检出率均显著高于低频CEUS[96.7%(29/30)vs.46.7%(14/30)、92.6%(25/27)vs.66.7%(18/27)、100%(26/26)vs.57.7%(15/26)],差异均有统计学意义(均P<0.001)。高频CEUS鉴别诊断浅表FLLs良恶性的灵敏度、准确率分别为92.9%、91.7%,均高于低频CEUS(78.6%、77.8%),差异均有统计学意义(均P<0.05)。结论高频CEUS在提高浅表FLLs的检出率和定性诊断方面均有明显优势,具有重要的临床价值。展开更多
文摘This study evaluated the value of high-frequency ultrasonograpy for early detection of dorsal artery of foot in patients with type 2 diabetes mellitus （MD）. Eighty subjects including 40 patients with type 2 MD （T2DM group） and 40 healthy volunteers （NC group） were recruited. The intima-media thickness （IMT）, the inner diameter and the perfusion of dorsal artery of foot were measured by using high-frequency ultrasonograpy. Meanwhile, the parameters of vascular elasticity, including stiffness parameter （]3）, pressure-strain elastic modulus （Ep）, arterial compliance （AC）, augment index （AI）, and pulse wave conducting velocity （PWV]3） were detected by means of echo-tracking technique. The results showed that no significant difference was found in the IMT, systolic diameter （Ds）, diastolic diameter （Dd） and peak systolic velocity （PSV） between T2DM and NC groups. Ep and PWVβ were increased, and AC was decreased in T2DM group as compared with those in NC group with the differences being significant （P〈0.05 for all）. There was no significant difference in β and AI between T2DM and NC groups. It was concluded that high-frequency ultra- sonography in combination with echo-tracking technique is sensitive and non-invasive, and can be used for early detection of sclerosis of the lower extremity artery in patients with type 2 MD.
基金supported by agrant from the New Technology and Service Project of Tongji Hospital(2008057)
文摘BACKGROUND: It is a globally challenging problem to differentially diagnose biliary atresia (BA) from other disease processes causing infantile cholestatic jaundice. The high frequency ultrasonography (HUS) yields much improved spatial resolution and therefore, might show better image in BA diagnostic examination. The present study was to evaluate the HUS on the diagnosis of BA in infants with jaundice. METHODS: Fifty-one infants with neonatal jaundice were scanned with ultrasonography. Images included gallbladder, bile duct, right hepatic artery (RHA), portal vein (PV) and triangular cord (TC) sign, magnetic resonance imaging and additionally laboratory tests and histopathology reports were assessed. RESULTS: Twenty-three BA and 28 non-BA cases were con firmed. The sensitivity, specificity, and accuracy of HUS were 91.3%, 92.9%, and 92.2%, respectively. All of these indices were significantly higher than those of conventional ultrasonography (P【0.01) and MR cholangiopancreatography (P【0.05). The HUS features, included a positive TC sign, an increased RHA diameter and RHA-diameter to portal-vein-diameter ratio (RHA/PV) and abnormal gallbladder, were important in the diagnosis of BA. CONCLUSION: HUS provided better imaging of BA and should be considered as a primary modality in the differential diagnosis of infantile jaundice.
文摘目的探讨高频超声造影(CEUS)在浅表肝脏局灶性病变(FLLs)检出及诊断中的临床价值。方法选取我院浅表FLLs患者38例,共63个病变,分别使用低频凸阵探头和高频线阵探头对患者进行CEUS检查,比较低频CEUS与高频CEUS在病变可见度评分、检出率和良恶性鉴别诊断中的差异。结果浅表FLLs在高频CEUS下平均可见度评分和检出率分别为(3.62±0.79)分、93.7%(59/63),均显著高于低频CEUS[(2.44±1.04)分、57.1%(36/63)],差异均有统计学意义(均P<0.05)。高频CEUS对最大径≤1 cm FLLs、最大径1~2 cm FLLs和肝转移瘤的检出率均显著高于低频CEUS[96.7%(29/30)vs.46.7%(14/30)、92.6%(25/27)vs.66.7%(18/27)、100%(26/26)vs.57.7%(15/26)],差异均有统计学意义(均P<0.001)。高频CEUS鉴别诊断浅表FLLs良恶性的灵敏度、准确率分别为92.9%、91.7%,均高于低频CEUS(78.6%、77.8%),差异均有统计学意义(均P<0.05)。结论高频CEUS在提高浅表FLLs的检出率和定性诊断方面均有明显优势,具有重要的临床价值。
