Experimental and clinical study of influence of high-frequency electric surgical knives on healing of abdominal incision

AIM： To study the influence of high-frequency electric surgical knives on healing of abdominal incision. METHODS： Two hundred and forty white rats were divided into 10^0, 10^2, 10^5, and 10^8 groups and rat models of abdominal operation were induced by using electric surgical knives and common lancets respectively. Then they were respectively given hypodermic injections of normal saline and 0.2 mL quantitative mixture of Escherichia coil, Staphylococcus aureus and Pseudornonas aeruginosa at a concentration of 10^2, 10^5 and 10^8. On the basis of the animal experiment, 220 patients undergoing abdominal operations （above type Ⅱ） were randomly allocated into one of following three groups： electric knife （EK, 93 cases）, electro-coagulation （EC, 55 cases） and control （72 cases）. High-frequency electric surgical knives were used to dissect abdominal tissues and electro-coagulation for hemostasis in EK group. Common lancets and electro-coagulation were applied in EC group. Common lancets and tieing silk suture were used in the controls. RESULTS： In all the groups except group 10^0, infection rate of incisional wounds made by electric surgical knives were remarkably higher than that with common lancets. Furthermore, there were significant differences in groups 10^2, 10^5, and 10^8 （P 〈 0.05）, but not in group 10^0 （P 〉 0.05） between EK and EC groups. Clinical studies showed a delayed wound healing in 16 cases （17.20%） in EK, 11 cases （16.36%） in EC and 2 cases （2.86%）in the control groups. A significant difference between EK and the control groups （χ^2= 8.57, P 〈 0.01）, and between EC and the control groups （χ^2 = 5.66, P 〈 0.05） was observed, but not between EK and EC （χ^2= 0.017, P 〉 0.05）. CONCLUSION： High-frequency electric knives may remarkably delay abdominal incision healing. Its application should be minimized so as to reduce the possibility of postoperative complications.

Morphology and electrical conductivity of PACS

Polyaluminium chlorides with sulfate ion(PACS) were prepared by using AlCl 3·6H 2O, Al(SO 4) 3·18H 2O and Na 2CO 3 as raw materials. The effects of basicity ( r ), Al 3+ /SO 4 2- molar ratio and aging time on the morphology of PACS were observed by transmission electrical microscope. The influence of aging time on charge neutralization and coagulation effect of PACS was studied. The effects of basicity ( r ), Al 3+ /SO 4 2- molar ratio and aging time on the electrical conductivity of PACS solution were also investigated. The experimental results show that the degree of polymerization of polyaluminium chloride(PAC) increases when SO 4 2- ion is added. The higher the basicity( r ) and the longer the aging time, the larger the size of polymer PACS. The ability of PACS neutralizing the charge on Kaolinite decreases with the increase of aging time. The electrical conductivity of PACS solution(the concentration of Al 3+ ion is 0.18 mol/L) with different aging time is the function of the basicity and Al 3+ /SO 4 2- molar ratios and has its maximum at r =0.5 and Al 3+ /SO 4 2- =12.

High-frequency spinal cord stimulation produces longlasting analgesic effects by restoring lysosomal function and autophagic flux in the spinal dorsal horn

High-frequency spinal cord stimulation(HF-SCS) has been established as an effective therapy for neuropathic pain. However, the analgesic mechanisms involved in HF-SCS remain to be clarified. In our study, adult rat neuropathic pain was induced by spinal nerve ligation. Two days after modeling, the rats were subjected to 4 hours of HF-SCS(motor threshold 50%, frequency 10,000 Hz, and pulse width 0.024 ms) in the dorsal horn of the spinal cord. The results revealed that the tactile allodynia of spinal nerve-injured rats was markedly alleviated by HFSCS, and the effects were sustained for 3 hours after the stimulation had ceased. HF-SCS restored lysosomal function, increased the levels of lysosome-associated membrane protein 2(LAMP2) and the mature form of cathepsin D(matu-CTSD), and alleviated the abnormally elevated levels of microtubule-associated protein 1 A/B-light chain 3(LC3)-II and sequestosome 1(P62) in spinal nerve-injured rats. HF-SCS also mostly restored the immunoreactivity of LAMP2, which was localized in neurons in the superficial layers of the spinal dorsal horn in spinal nerve-injured rats. In addition, intraperitoneal administration of 15 mg/kg chloroquine for 60 minutes reversed the expression of the aforementioned proteins and shortened the timing of the analgesic effects of HF-SCS. These findings suggest that HF-SCS may exhibit longlasting analgesic effects on neuropathic pain in rats through improving lysosomal dysfunction and alleviating autophagic flux. This study was approved by the Laboratory Animal Ethics Committee of China Medical University, Shenyang, China(approval No. 2017 PS196 K) on March 1, 2017.

The electrical parameters measurement system for electrotome output based on Labview

An accurate detection of the effective values of electric voltage and current from high frequency power generators is a precondition for the development of smart electrotomes. In this light, an energy detection system based on personal computer (PC) is developed hereby. It senses voltage and current in isolation from generators with transformers, and then the measured values are amplified, filtered, transformed into single-ended signals and converted to RMS. The detected signals are transformed into digital signals through Data Acquisition Card (DAQ) and the data are processed with quadratic fit in Labview. Finally, the controller completes constant power output. The experiment results indicate that the energy detection system can measure the output parameters precisely and the controller can achieve constant power control.

Hippocampal High-Frequency Stimulation Inhibites the Progression of Rapid Kindling-Induced Seizure in Rats

Epilepsy is one of the most common serious neurological disorders. Pharmacoresistant epilepsy patients are poorly controlled or their seizures are refractory to drug treatment. Resective surgery is frequently a promising therapy in this population, however, not all the patients meet the eligibility criteria for the surgical treatment. Deep brain stimulation has been investigated in clinical studies and animal studies as an alternative treatment, but the optimal stimulation parameters remain an issue. The present study was designed to investigate the effect of unilateral high-frequency stimulation (HFS) of hippocampus on seizure development by using the hippocampal rapid kindling method (hRK) in rats, and compared the results with those of low-frequency stimulation previously published by our group. We used male Wistar rats implanted with electrodes in the ventral hippocampus. All rats underwent hRK (biphasic square wave pulses, 20 Hz for 10 seconds) during three consecutive days (twelve stimulations per day). The control group (hRK;n = 7) received only RK stimulus, while the treated group (HFS-hRK;n = 9) received also HFS (biphasic square wave pulses, 130 Hz for 30 seconds) immediately before the RK stimulus, during three consecutive days. At the end of behavioral testing 78% (p 0.01) of the animals receiving HFS treatment were still not fully kindled staying in stages 0 -III (p 0.01). HFS group needed a higher number of stimulations to achieve stage III (p 0.05) with respect to control group. However, no significant differences in the cumulative daily afterdischarge duration were observed. HFS did not present significant differences compared with LFS in any of studied parameters. The findings suggest that unilateral HFS applied on hippocampus effectively inhibited the epileptogenic process induced by hippocampal rapid kindling. According to the comparative results about hippocampal rapid kindled animals stimulated with HFS and LFS (5 Hz), we found no conclusive information on which treatment is most efficient.

内镜下黏膜切除术与高频电凝电切术治疗结肠巨大息肉效果及安全性分析

目的:探究内镜下黏膜切除术(EMR)治疗结肠巨大息肉的效果。方法:选择2019年5月—2022年5月在大连市第三人民医院进行治疗的110例结肠巨大息肉患者,应用随机数字表法将其分为对照组(行高频电凝电切术)及研究组(行EMR),各55例。对比两组临床指标(手术时间、住院时间)、临床疗效、应激反应[肾上腺素(E)、去甲肾上腺素(NE)、皮质醇(Cor)]、炎症反应[白细胞介素-6(IL-6)、白细胞介素-12(IL-12)、白细胞介素-1β(IL-1β)]、并发症发生情况。结果:研究组手术时间、住院时间均短于对照组,差异均有统计学意义(P<0.05)。研究组临床疗效优于对照组,差异有统计学意义(P<0.05)。与术前比较,术后两组E、NE、Cor均升高,研究组上述指标均低于对照组,差异均有统计学意义(P<0.05)。与术前比较,术后两组IL-6、IL-12、IL-1β均升高,研究组上述指标均低于对照组,差异均有统计学意义(P<0.05)。研究组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:结肠巨大息肉患者行EMR治疗,可提高临床疗效,减轻炎症反应、应激反应,减少并发症发生,促进康复。

经皮电刺激配合艾灸八髎穴治疗寒凝血瘀型原发性痛经的临床效果

目的探讨经皮电刺激配合艾灸八髎穴治疗寒凝血瘀型原发性痛经的效果。方法选取2023年1月至6月江西省妇幼保健院收治的200例寒凝血瘀型原发性痛经患者作为研究对象,采用随机数字表法将其分为对照组与治疗组,每组100例。对照组采用布洛芬缓释胶囊治疗,治疗组采用经皮电刺激联合艾灸八髎穴治疗,比较两组患者的疗效、中医证候积分、疼痛评分、不良反应发生率。结果治疗组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗组治疗3个月时的中医证候积分、视觉模拟评分法(VAS)评分均低于对照组,差异有统计学意义(P<0.05)。两组患者不良反应总发生率比较,差异无统计学意义(P>0.05)。结论采用经皮电刺激联合艾灸八髎穴对寒凝血瘀型原发性痛经患者进行治疗,可改善痛经症状,且安全性高,值得临床广泛应用及推广。

粉煤灰不同掺量对高性能混凝土耐久性影响研究

为了研究粉煤灰掺量对高性能混凝土材料耐久性影响,在P·O42.5级高性能混凝土中掺入10%、20%、30%、50%的粉煤灰。设计混凝土、粉煤灰掺量的试验配合比,将粉煤灰掺量和高性能混凝土配合比作为正交试验的2个变量。试验结果表明,正常环境下10%、20%、30%时的混凝土渗透率较低,抗压强度大,50%的混凝土渗透率较高且抗压强度有所减小,冻融环境下的各个数据值均小于正常环境,说明适量掺入粉煤灰掺量能够提高混凝土材料耐久性。通过对试验数据整理可知,使用所研究方法混凝土渗透率、抗压强度与统计数据均存在最大仅为1%和0.1 MPa的误差,能够将试验研究结果作为实际工程可行的条件。

高频电刀在重睑成形术中的应用效果

目的比较高频电刀和手术刀在重睑成形术中的应用效果。方法回顾性分析上海交通大学医学院附属第九人民医院2021年1月至7月收治的眼部整形者35例(70眼),随机选取一侧眼为高频电刀组(采用高频电刀行手术),另一侧眼为手术刀组(采用手术刀行手术),每组35眼。评估术后双眼重睑成形效果。术后1 d、1周、1个月及3个月观察患者肿胀情况及瘀斑形成情况。术后1周、1个月、3个月采用曼彻斯特瘢痕量表(MSS)评估患者瘢痕情况。将切除的组织行HE染色和TUNEL染色,评估皮肤和肌肉的坏死程度和热损伤范围。结果术后患者双眼在肿胀、瘀斑、疼痛及瘢痕形成方面差异均无统计学意义(P>0.05)。高频电刀组眼睑出现肌肉组织凝固性坏死,手术刀组几乎无凝固性坏死;患者双眼术后凝固性坏死肌肉占比比较差异有统计学意义(P<0.05),高频电刀组热损伤深度大于手术刀组(P<0.05)。结论高频电刀在重睑成形术中操作简单,使用安全,术中切凝及时,可获得良好的手术术野及效果。

Observations on Curative Effect of High-frequency Electric Sparkle and Point-injection Therapy on Knee Osteoarthritis

Objective: To observe the curative effect of high-frequency electric sparkle and point-injection therapy (HESPT) on knee osteoarthritis (KOA). Methods: Two hundred and five patients were randomly divided into a warming needle moxibustion group (68 cases), a HESPT group (68 cases) and a point-injection group (69 cases). In the warming needle moxibustion group, the main points of Xuehai (SP 10), Neixiyan (EX-LE4), Waixiyan (EX-LE5), Dubi (ST 35), Zusanli (ST 36) and Yanglingquan (GB 34), and the adjunct points of Yinlingquan (SP 9) and Sanyinjiao (SP 6), on the affected side, were chosen for stimulation. In the HESPT group, tenderness points, the main points of Liangqiu (ST 34), Xuehai (SP 10), Neixiyan (EX-LE4), Waixiyan (EX-LE5) and Zusanli (ST 36), and the adjunct points of Yinlingquan (SP 9), Weizhong (BL 40) and Chengshan (BL 57), were chosen. After proper manipulation, Corydalis decumbens Pers. liquid was injected into the points and a high-frequency electric sparkle was applied to stimulate the needles for 30 seconds. In the point-injection group, point injection was performed with the same method, but the patients did not receive electric stimulation. The Western Ontario and McMaster University Osteoarthritis Index (WOMAC), the Lysholm Knee Score Scale (LKSS) and the ROM (Range of Motion) scale were used to evaluate the severity of KOA and the function of knee joints before treatment and 4 weeks after treatment. Finally, the Nimodipine method was used to assess the total curative effect. Results: After HESPT treatment, the scores for pain, morning stiffness and swelling were significantly lower (P<0.01) and LKSS index and ROM were much higher (P<0.01 and P<0.05 respectively) compared to the two other groups. The obviously effective rate and total effective rate were also significantly higher in the HESPT group than in the two other groups (P<0.01 or P<0.05). Conclusion: HESPT can improve joint function in KOA patients, and the curative effect is better than for warming needle moxibustion or point-injection only.

Saline conducted electric coagulation (SCEC):original experience in experimental hepatectomy

Objective: To evaluate the feasibility and superiority of a new coagulating and hemostatic method named "saline conducted electric coagulation (SCEC)". Methods: The Peng's multifunction operative dissector (PMOD) was modified to enable saline to effuse persistently out of its nib at a constant speed. In a group of six New Zealand rabbits, two hepatic lobes of each rabbits were resected respectively by SCEC and conventional electric coagulation (EC). The features of SCEC were recorded by photo and compared with conventional EC. After 7 d, the coagulating depth was measured in each residual hepatic lobe. Hepatic tissue was dyed by hematoxylin and eosin (HE) and studied under a microscope. Results: The coagulating depth increased with the continuation of SCEC time. Hepatectomies were performed successfully, no rabbit died in the perioperative period. The incisal surface of SCEC was gray-white with no red bleeding point. There was a thick solidified layer at the margin and a thin red-white intermittent layer between the solidified layer and normal hepatic tissue at the vertical section of SCEC. The mean coagulating depth of SCEC was 1.8 cm vs. 0.3 cm of conventional EC. Pathological examination showed a mild inflammatory reaction by SCEC. Conclusions: SCEC is a feasible and safe method for surgical hemostasis. As a new technique for liver resection, SCEC shows better coagulating effect and milder inflammatory reaction than conventional EC. Our study shows bloodless liver resection can also be performed by SCEC, especially for liver malignant tumor.

重型颅脑损伤昏迷患者经正中神经电刺激促苏醒前后脑损伤与凝血功能对比

目的探究重型颅脑损伤昏迷患者接受正中神经电刺激促苏醒干预前后的脑损伤和凝血功能变化的情况。方法随机选取2019年1月—2021年6月福建省立医院收治的100例重型颅脑损伤昏迷患者作为研究对象,均给予患者促苏醒干预,包括心肺复苏等,随后根据患者治疗1个月的格拉斯哥预后评分分为预后良好组(4~5分)和预后不良组(1~3分),每组50例。另外选取同期接受检查的50例健康患者作为对照组,对比分析3组凝血功能指标变化和脑损伤程度。结果预后不良组重症急性生理与慢性健康状况评分、S-中枢神经特异性蛋白、神经元特异性烯醇化酶、胶质纤维酸性蛋白、β-淀粉样蛋白、髓鞘碱性蛋白分别为(28.51±7.90)分、(3.27±1.66)μg/L、(38.45±13.23)μg/L、(5.73±1.76)μg/L、(41.29±12.85)pg/mL、(13.45±4.54)ng/mL,均高于预后良好组,并且预后良好组高于对照组,3组对比差异有统计学意义(t_(预后不良组与预后良好组)=7.736、10.164、7.872、13.492、6.773、6.921,t_(预后良好组与对照组)=13.536、16.099、13.635、21.933、11.861、7.683,t_(预后不良组与对照组)=23.041、13.460、17.568、22.493、15.941、12.693,P<0.05)。同时,预后不良组凝血酶原时间(15.34±1.55)s、凝血酶时间(23.54±4.59)s、活化部分凝血活酶时间(39.45±7.65)s、D-二聚体(421.42±69.59)μg/L水平最高,血小板计数(89.33±16.34)×10^(9)/L、纤维蛋白原(2.13±0.66)g/L水平最低,表明预后不良组凝血功能最差,其次为预后良好组,3组对比差异有统计学意义(P<0.05)。结论急性脑损伤患者会表现出APTT、PT、TT、D-D等凝血功能指标与常规脑损伤相关指标升高的情况,同时PLT、Fg水平降低,以上指标的变化情况可作为临床诊断的指标和标准。

基于STM32的生物电阻抗测量系统的设计与应用

为了更好地了解患者的血凝病理状况,方便医生及时用药,基于STM32和AD5933设计了一种血凝电阻抗测量系统。使用该系统测量标准电阻、电容构成的RC并联网络,与TH2832LCR电桥仪对比,误差小于0.9%;进行标准电阻的扫频测量,误差小于0.5%。提出一种凝血因子反应时间R检测方法,对40组血样进行测量,并与实际R值对比,误差均小于4%;使用等浓度差的CaCl_(2)溶液与多组枸橼酸钠抗凝血混合,发现随着CaCl_(2)溶液浓度以0.025mol/L微量减小,R明显增大,符合生物学规律;在不同条件下对多组血样进行测量,误差均小于5%。结果表明该电阻抗测量系统可以用于凝血因子反应时间的检测,且具有较高的精度、灵敏度和较好的重复性、重现性。

不同保湿预处理对双极电凝钳清洗质量的影响

目的:观察不同保湿预处理方法对双极电凝钳清洗效果的影响。方法:选择某医院手术室2021年6月—2021年12月使用后的双极电凝钳240件作为研究对象,采用分层随机化分组方法随机分为对照组、观察1组、观察2组,每组80件。保湿前,3组均将器械拆分至最小单位,关节完全打开。对照组依据医院现行的操作方式,将配好的保湿液直接喷洒在器械上进行保湿密闭保存。观察1组在对照组的基础上用流动水冲洗外表面及管腔内壁的血渍、污渍,并用小软毛刷对关节咬合处重点清洗,然后进行保湿、密闭处理。观察2组在观察1组操作基础上,以脉冲式冲洗方法反复冲洗管腔,直至另一端无污物流出,然后用同样的方法清洗关节咬合处,保湿、密闭保存。最后,3组采用相同的清洗方式,清洗液浸泡超声+人工刷洗+高压水枪冲洗法,放入真空沸腾式清洗机清洗。比较3组双极电凝钳的清洗质量。结果:观察2组的管腔内壁、关节咬合的清洗合格率最高,观察1组次之,对照组的清洗合格率最低,3组比较差异有统计学意义(P<0.05);3组外表面的清洗质量比较差异无统计学意义(P>0.05)。结论:不同的预处理方式对双极电凝钳的清洗质量有影响,其中脉冲式清洗管腔、软毛刷清洗关节咬合处可明显提高清洗质量。

电脱盐反冲洗废水稳定性研究

电脱盐反冲洗废水污染组成复杂,废水乳化带油严重,破乳分离困难。文章对比分析了电脱盐反冲洗废水与正常排水的水质特性,通过Zeta电位、表面张力和稳定性分析探究了体积稀释比对反冲洗废水稳定性的影响,考察了不同体积稀释比及转速与电脱盐反冲洗废水沉降或上浮速率的关系。结果表明:电脱盐反冲洗废水COD为55 785 mg/L,是正常排水的10.8倍,以非溶解性有机物为主;反冲洗废水Zeta电位为-2.5 mV,当体积稀释比为90%时,Zeta电位为-14.8 mV,随着体积稀释比降低,Zeta电位稳定在-14~-18 mV;反冲洗废水表面张力为42.20 mN/m,体积稀释比由100%变化至70%时,表面张力变化不大,但随着体积稀释比降低,表面张力呈增加趋势;反冲洗废水的不稳定性指数约为0.05,当体积稀释比从90%变化至1%时,不稳定性指数升高,而且转速由500 r/min增加至1 000 r/min时,不稳定性指数也有所升高;电脱盐反冲洗废水体积稀释比为80%~90%时,适于上浮处理;体积稀释比为20%~40%时,适于沉降处理。研究成果可为电脱盐废水混凝脱稳与气浮沉淀分离处理提供参考。

Total Electricity Consumption Forecasting Based on Temperature Composite Index and Mixed-Frequency Models

The total electricity consumption(TEC)can accurately reflect the operation of the national economy,and the forecasting of the TEC can help predict the economic development trend,as well as provide insights for the formulation of macro policies.Nowadays,high-frequency and massive multi-source data provide a new way to predict the TEC.In this paper,a"seasonal-cumulative temperature index"is constructed based on high-frequency temperature data,and a mixed-frequency prediction model based on multi-source big data(Mixed Data Sampling with Monthly Temperature and Daily Temperature index,MIDAS-MT-DT)is proposed.Experimental results show that the MIDAS-MT-DT model achieves higher prediction accuracy,and the"seasonal-cumulative temperature index"can improve prediction accuracy.

胃肠镜下氩离子凝固术与高频电圈套电切术治疗大直径胃肠息肉的效果对比

目的 探究胃肠道较大息肉患者接受常规内镜下氩离子凝固术与胃肠镜下高频电圈套电切术的疗效差异。方法 回顾性分析选取2021年1月至2022年3月平顶山市第二人民医院择期手术治疗的130例胃肠道较大息肉患者作为研究对象,根据手术方式不同分为对照组和观察组,各65例。予以对照组常规内镜下氩离子凝固术治疗,予以观察组胃肠镜下高频电圈套电切术治疗。评价两组患者一次性治愈率及生活质量;记录两组患者并发症发生情况。结果 对照组一次性治愈率81.54%(53/65),观察组一次性治愈率93.85%(61/65),观察组相比对照组显著更高,两组差异有统计学意义(P<0.05)。观察组消化病生存质量指数(GLQI)总分及各维度得分相比对照组均显著更高,两组差异有统计学意义(P<0.05)。对照组2例迟发出血,2例腹胀,1例穿孔,并发症总发生率7.69%;观察组1例迟发出血,3例腹胀,2例穿孔,并发症总发生率9.23%;两组对比差异无统计学意义(P>0.05)。结论 胃肠镜下高频电圈套电切术应用于胃肠道较大息肉患者中,相比常规内镜下氩离子凝固术效果更好,明显提升一次性治愈率,改善生活质量,安全性较高,值得临床广泛应用。

复合聚硅酸铁混凝剂的制备、性能与混凝机理研究

为探明硅铁物质的量比对聚硅酸铁混凝效果的影响规律,以Na_(2)SiO_(3)·5H_(2)O、Fe_(2)(SO_(4))_(3)·7H_(2)O为原料制备6种聚硅酸铁,通过XRD、SEM及FTIR等分析手段对聚硅酸铁进行物相和微观形貌表征,并系统研究了聚硅酸铁用量、pH值、搅拌时间等工艺参数对COD去除率的影响。结果表明:①聚硅酸铁具有多晶相结构,随硅铁物质的量比的增加,表面形貌由空心管状逐渐向片状结构转变。②随着硅铁物质的量比的增加,聚硅酸铁中Fe(Ⅲ)的自由离子、单核羟基络合物含量减少,聚硅酸铁的电中和能力减弱;相应硅酸多聚体含量升高,聚硅酸铁吸附架桥能力得到提升。③针对丁基钠黄药和二号油所制备水样,采用硅铁物质的量比为0.5的聚硅酸铁混凝剂净化处理,在聚硅酸铁用量为4 mmol/L、pH值为5.0、搅拌时间为20 min的条件下,COD去除率可达到48%。与Fe_(2)(SO_(4))_(3)·7H_(2)O、聚硅酸相比,聚硅酸铁混凝性能明显提升,混凝过程电中和与吸附架桥共同作用。

内镜下电凝与钛夹治疗消化性溃疡出血患者的效果比较

目的比较内镜下电凝与钛夹治疗消化性溃疡出血患者的效果。方法选取2018年1月至2020年12月我院收治的78例消化性溃疡出血患者作为研究对象,根据治疗方案不同将其分为电凝组(39例,内镜下电凝治疗)和钛夹组(39例,内镜下钛夹治疗)。比较两组的治疗效果。结果两组的治疗总有效率比较,差异无统计学意义(P>0.05)。钛夹组的手术中转率、再出血率低于电凝组(P<0.05);两组的输血量比较,差异无统计学意义(P>0.05)。术后3 d,两组的应激反应指标及炎症因子水平均升高,但钛夹组低于电凝组(P<0.05)。结论内镜下电凝与钛夹治疗消化性溃疡出血均具有较好的效果,但内镜下电凝更易出现再出血和手术中转,且应激反应和炎症反应更重。

腹腔镜卵巢巧克力囊肿剥除术电凝止血对卵巢储备功能的影响

目的:探讨腹腔镜下卵巢巧克力囊肿剥除术中创面采用电凝止血方法对术后卵巢功能的影响。方法:选取有腹腔镜手术适应证的卵巢巧克力囊肿患者39例,术中创面采用电凝法止血,于术前、术后及术后6个月抽血检测FSH、LH、E2及阴道B超探测窦状卵泡数(Fo)、卵巢间质动脉血流的收缩期峰值(PSV)以判断卵巢储备功能。结果:术后及术后6个月较术前的FSH显著升高(P<0.05),E2、Fo、PSV显著降低(P<0.01);患者术前基础内分泌指标、窦状卵泡数及FSH/LH的比值均在正常范围。术后检查共发现8例(24.2%)卵巢储备功能下降的患者。结论:腹腔镜下卵巢巧克力囊肿剥除术中电凝止血法易致卵巢储备功能降低。