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Anorectal dysfunction in patients with mid-low rectal cancer after surgery: A pilot study with three-dimensional high-resolution manometry 被引量:1
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作者 Yan-Na Pi Yi Xiao +3 位作者 Zhi-Feng Wang Guo-Le Lin Hui-Zhong Qiu Xiu-Cai Fang 《World Journal of Clinical Cases》 SCIE 2022年第12期3754-3763,共10页
BACKGROUND The quality of life in patients who develop low anterior resection syndrome(LARS)after surgery for mid-low rectal cancer is seriously impaired.The underlying pathophysiological mechanism of LARS has not bee... BACKGROUND The quality of life in patients who develop low anterior resection syndrome(LARS)after surgery for mid-low rectal cancer is seriously impaired.The underlying pathophysiological mechanism of LARS has not been fully investigated.AIM To assess anorectal function of mid-low rectal cancer patients developing LARS perioperatively.METHODS Patients diagnosed with mid-low rectal cancer were included.The LARS score was used to evaluate defecation symptoms 3 and 6 mo after anterior resection or a stoma reversal procedure.Anorectal functions were assessed by threedimensional high resolution anorectal manometry preoperatively and 3-6 mo after surgery.RESULTS The study population consisted of 24 patients.The total LARS score was decreased at 6 mo compared with 3 mo after surgery(P<0.05),but 58.3%(14/24)lasted as major LARS at 6 mo after surgery.The length of the high-pressure zone of the anal sphincter was significantly shorter,the mean resting pressure and maximal squeeze pressure of the anus were significantly lower than those before surgery in allpatients (P < 0.05), especially in the neoadjuvant therapy group after surgery (n = 18). The focalpressure defects of the anal canal were detected in 70.8% of patients, and those patients had higherLARS scores at 3 mo postoperatively than those without focal pressure defects (P < 0.05). Spasticperistaltic contractions from the new rectum to anus were detected in 45.8% of patients, whichwere associated with a higher LARS score at 3 mo postoperatively (P < 0.05).CONCLUSIONThe LARS score decreases over time after surgery in the majority of patients with mid-low rectalcancer. Anorectal dysfunctions, especially focal pressure defects of the anal canal and spasticperistaltic contractions from the new rectum to anus postoperatively, might be the majorpathophysiological mechanisms of LARS. 展开更多
关键词 Low anterior resection syndrome Anorectal function Three-dimensional high-resolution manometry Rectal cancer
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Distal esophageal spasm:Update on diagnosis and management in the era of high-resolution manometry 被引量:1
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作者 Harika Gorti Salih Samo +1 位作者 Nikrad Shahnavaz Emad Qayed 《World Journal of Clinical Cases》 SCIE 2020年第6期1026-1032,共7页
Distal esophageal spasm(DES)is a rare major motility disorder in the Chicago classification of esophageal motility disorders(CC).DES is diagnosed by finding of≥20%premature contractions,with normal lower esophageal s... Distal esophageal spasm(DES)is a rare major motility disorder in the Chicago classification of esophageal motility disorders(CC).DES is diagnosed by finding of≥20%premature contractions,with normal lower esophageal sphincter(LES)relaxation on high-resolution manometry(HRM)in the latest version of CCv3.0.This feature differentiates it from achalasia type 3,which has an elevated LES relaxation pressure.Like other spastic esophageal disorders,DES has been linked to conditions such as gastroesophageal reflux disease,psychiatric conditions,and narcotic use.In addition to HRM,ancillary tests such as endoscopy and barium esophagram can provide supplemental information to differentiate DES from other conditions.Functional lumen imaging probe(FLIP),a new cutting-edge diagnostic tool,is able to recognize abnormal LES dysfunction that can be missed by HRM and can further guide LES targeted treatment when esophagogastric junction outflow obstruction is diagnosed on FLIP.Medical treatment in DES mostly targets symptomatic relief and often fails.Botulinum toxin injection during endoscopy may provide a temporary therapy that wears off over time.Myotomy through peroral endoscopic myotomy or via surgical Heller myotomy can provide long term relief in cases with persistent symptoms. 展开更多
关键词 DISTAL ESOPHAGEAL SPASM high-resolution manometry Esophagus Functional lumenal imaging probe SPASTIC ACHALASIA ESOPHAGEAL motility
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Preoperative physiological esophageal assessment for anti-reflux surgery:A guide for surgeons on high-resolution manometry and pH testing 被引量:1
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作者 Michael Yodice Alexandra Mignucci +2 位作者 Virali Shah Christopher Ashley Micheal Tadros 《World Journal of Gastroenterology》 SCIE CAS 2021年第16期1751-1769,共19页
Gastroesophageal reflux disease (GERD) is one of the most commonlyencountered digestive diseases in the world, with the prevalence continuing toincrease. Many patients are successfully treated with lifestyle modificat... Gastroesophageal reflux disease (GERD) is one of the most commonlyencountered digestive diseases in the world, with the prevalence continuing toincrease. Many patients are successfully treated with lifestyle modifications andproton pump inhibitor therapy, but a subset of patients require more aggressiveintervention for control of their symptoms. Surgical treatment with fundoplicationis a viable option for patients with GERD, as it attempts to improve the integrityof the lower esophageal sphincter (LES). While surgery can be as effective asmedical treatment, it can also be associated with side effects such as dysphagia,bloating, and abdominal pain. Therefore, a thorough pre-operative assessment iscrucial to select appropriate surgical candidates. Newer technologies arebecoming increasingly available to help clinicians identify patients with true LESdysfunction, such as pH-impedance studies and high-resolution manometry(HRM). Pre-operative evaluation should be aimed at confirming the diagnosis ofGERD, ruling out any major motility disorders, and selecting appropriate surgicalcandidates. HRM and pH testing are key tests to consider for patients with GERDlike symptoms, and the addition of provocative measures such as straight legraises and multiple rapid swallows to HRM protocol can assess the presence ofunderlying hiatal hernias and to test a patient’s peristaltic reserve prior tosurgery. 展开更多
关键词 Gastroesophageal reflux disease FUNDOPLICATION High resolution manometry pH-impedance Anti-reflux surgery Pre-operative assessment
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New technologies in the gastrointestinal clinic and research: Impedance and high-resolution manometry 被引量:4
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作者 John E Pandolfino Peter J Kahrilas 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第2期131-138,共8页
The last five years have been an exciting time in the study of esophageal motor disorders due to the recent advances in esophageal function testing. New technologies have emerged, such as intraluminal impedance, while... The last five years have been an exciting time in the study of esophageal motor disorders due to the recent advances in esophageal function testing. New technologies have emerged, such as intraluminal impedance, while conventional techniques, such as manometry, have enjoyed many improvements due to advances in transducer technology, computerization and graphic data presentation. While these techniques provide more detailed information regarding esophageal function, our understanding of whether they can improve our ability to diagnose and treat patients more effectively is evolving. These techniques are also excellent research tools and they have added substantially to our understanding of esophageal motor function in dysphagia. This review describes the potential benefits that these new technologies may have over conventional techniques for the evaluation of dysphagia. 展开更多
关键词 消化系统 胃肠疾病 吞咽困难 治疗方法
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Verification and Validation of High-Resolution Inviscid and Viscous Conical Nozzle Flows
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作者 Luciano K.Araki Rafael B.de R.Borges +1 位作者 Nicholas Dicati P.da Silva Chi-Wang Shu 《Communications on Applied Mathematics and Computation》 EI 2024年第1期533-549,共17页
Capturing elaborated flow structures and phenomena is required for well-solved numerical flows.The finite difference methods allow simple discretization of mesh and model equations.However,they need simpler meshes,e.g... Capturing elaborated flow structures and phenomena is required for well-solved numerical flows.The finite difference methods allow simple discretization of mesh and model equations.However,they need simpler meshes,e.g.,rectangular.The inverse Lax-Wendroff(ILW)procedure can handle complex geometries for rectangular meshes.High-resolution and high-order methods can capture elaborated flow structures and phenomena.They also have strong mathematical and physical backgrounds,such as positivity-preserving,jump conditions,and wave propagation concepts.We perceive an effort toward direct numerical simulation,for instance,regarding weighted essentially non-oscillatory(WENO)schemes.Thus,we propose to solve a challenging engineering application without turbulence models.We aim to verify and validate recent high-resolution and high-order methods.To check the solver accuracy,we solved vortex and Couette flows.Then,we solved inviscid and viscous nozzle flows for a conical profile.We employed the finite difference method,positivity-preserving Lax-Friedrichs splitting,high-resolution viscous terms discretization,fifth-order multi-resolution WENO,ILW,and third-order strong stability preserving Runge-Kutta.We showed the solver is high-order and captured elaborated flow structures and phenomena.One can see oblique shocks in both nozzle flows.In the viscous flow,we also captured a free-shock separation,recirculation,entrainment region,Mach disk,and the diamond-shaped pattern of nozzle flows. 展开更多
关键词 high-resolution COMPRESSIBLE NAVIER-STOKES Free-shock separation Nozzle flow
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Accurate Source-Receiver Positioning Method for a High-Resolution Deep-Towed Multichannel Seismic Exploration System
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作者 LI Jing LIU Kai +5 位作者 WEI Zhengrong ZHANG Liancheng LIU Yangting PEI Yanliang LIU Chenguang LIU Baohua 《Journal of Ocean University of China》 CAS CSCD 2024年第2期415-426,共12页
The near-seabed multichannel seismic exploration systems have yielded remarkable successes in marine geological disaster assessment,marine gas hydrate investigation,and deep-sea mineral exploration owing to their high... The near-seabed multichannel seismic exploration systems have yielded remarkable successes in marine geological disaster assessment,marine gas hydrate investigation,and deep-sea mineral exploration owing to their high vertical and horizontal resolution.However,the quality of deep-towed seismic imaging hinges on accurate source-receiver positioning information.In light of existing technical problems,we propose a novel array geometry inversion method tailored for high-resolution deep-towed multichannel seismic exploration systems.This method is independent of the attitude and depth sensors along a deep-towed seismic streamer,accounting for variations in seawater velocity and seabed slope angle.Our approach decomposes the towed line array into multiline segments and characterizes its geometric shape using the line segment distance and pitch angle.Introducing optimization parameters for seawater velocity and seabed slope angle,we establish an objective function based on the model,yielding results that align with objective reality.Employing the particle swarm optimization algorithm enables synchronous acquisition of optimized inversion results for array geometry and seawater velocity.Experimental validation using theoretical models and practical data verifies that our approach effectively enhances source and receiver positioning inversion accuracy.The algorithm exhibits robust stability and reliability,addressing uncertainties in seismic traveltime picking and complex seabed topography conditions. 展开更多
关键词 high-resolution deep-towed multichannel seismic exploration source-receiver positioning array geometry inversion seawater heterogeneity seabed slope angle
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Investigating the relationship between intracranial atherosclerotic plaque remodelling and diabetes using high-resolution vessel wall imaging
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作者 Yong-Qian Mo Hai-Yu Luo +5 位作者 Han-Wen Zhang Yu-Feng Liu Kan Deng Xiao-Lei Liu Biao Huang Fan Lin 《World Journal of Diabetes》 SCIE 2024年第1期72-80,共9页
BACKGROUND Intracranial atherosclerosis,a leading cause of stroke,involves arterial plaque formation.This study explores the link between plaque remodelling patterns and diabetes using high-resolution vessel wall imag... BACKGROUND Intracranial atherosclerosis,a leading cause of stroke,involves arterial plaque formation.This study explores the link between plaque remodelling patterns and diabetes using high-resolution vessel wall imaging(HR-VWI).AIM To investigate the factors of intracranial atherosclerotic remodelling patterns and the relationship between intracranial atherosclerotic remodelling and diabetes mellitus using HR-VWI.METHODS Ninety-four patients diagnosed with middle cerebral artery or basilar artery INTRODUCTION Intracranial atherosclerotic disease is one of the main causes of ischaemic stroke in the world,accounting for approx-imately 10%of transient ischaemic attacks and 30%-50%of ischaemic strokes[1].It is the most common factor among Asian people[2].The adaptive changes in the structure and function of blood vessels that can adapt to changes in the internal and external environment are called vascular remodelling,which is a common and important pathological mechanism in atherosclerotic diseases,and the remodelling mode of atherosclerotic plaques is closely related to the occurrence of stroke.Positive remodelling(PR)is an outwards compensatory remodelling where the arterial wall grows outwards in an attempt to maintain a constant lumen diameter.For a long time,it was believed that the degree of stenosis can accurately reflect the risk of ischaemic stroke[3-5].Previous studies have revealed that lesions without significant luminal stenosis can also lead to acute events[6,7],as summarized in a recent meta-analysis study in which approximately 50%of acute/subacute ischaemic events were due to this type of lesion[6].Research[8,9]has pointed out that the PR of plaques is more dangerous and more likely to cause acute ischaemic stroke.Previous studies[10-13]have found that there are specific vascular remodelling phenomena in the coronary and carotid arteries of diabetic patients.However,due to the deep location and small lumen of intracranial arteries and limitations of imaging techniques,the relationship between intracranial arterial remodelling and diabetes is still unclear.In recent years,with the development of magnetic resonance technology and the emergence of high-resolution(HR)vascular wall imaging,a clear and multidimensional display of the intracranial vascular wall has been achieved.Therefore,in this study,HR wall imaging(HR-VWI)was used to display the remodelling characteristics of bilateral middle cerebral arteries and basilar arteries and to explore the factors of intracranial vascular remodelling and its relationship with diabetes. 展开更多
关键词 high-resolution vessel wall imaging Intracranial atherosclerosis Vascular remodelling Magnetic resonance imaging
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In vivo pilot study into superficial microcirculatory characteristics of colorectal adenomas using novel high-resolution magnifying endoscopy with blue laser imaging
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作者 Hai-Bin Dong Tao Chen +2 位作者 Xiao-Fei Zhang Yu-Tang Ren Bo Jiang 《World Journal of Gastrointestinal Endoscopy》 2024年第4期206-213,共8页
BACKGROUND No studies have yet been conducted on changes in microcirculatory hemody-namics of colorectal adenomas in vivo under endoscopy.The microcirculation of the colorectal adenoma could be observed in vivo by a n... BACKGROUND No studies have yet been conducted on changes in microcirculatory hemody-namics of colorectal adenomas in vivo under endoscopy.The microcirculation of the colorectal adenoma could be observed in vivo by a novel high-resolution magnification endoscopy with blue laser imaging(BLI),thus providing a new insight into the microcirculation of early colon tumors.AIM To observe the superficial microcirculation of colorectal adenomas using the novel magnifying colonoscope with BLI and quantitatively analyzed the changes in hemodynamic parameters.METHODS From October 2019 to January 2020,11 patients were screened for colon adenomas with the novel high-resolution magnification endoscope with BLI.Video images were recorded and processed with Adobe Premiere,Adobe Photoshop and Image-pro Plus software.Four microcirculation parameters:Microcirculation vessel density(MVD),mean vessel width(MVW)with width standard deviation(WSD),and blood flow velocity(BFV),were calculated for adenomas and the surrounding normal mucosa.RESULTS A total of 16 adenomas were identified.Compared with the normal surrounding mucosa,the superficial vessel density in the adenomas was decreased(MVD:0.95±0.18 vs 1.17±0.28μm/μm2,P<0.05).MVW(5.11±1.19 vs 4.16±0.76μm,P<0.05)and WSD(11.94±3.44 vs 9.04±3.74,P<0.05)were both increased.BFV slowed in the adenomas(709.74±213.28 vs 1256.51±383.31μm/s,P<0.05).CONCLUSION The novel high-resolution magnification endoscope with BLI can be used for in vivo study of adenoma superficial microcirculation.Superficial vessel density was decreased,more irregular,with slower blood flow. 展开更多
关键词 ADENOMA MICROCIRCULATION high-resolution magnification endoscopy Blue laser imaging
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Few-Shot Object Detection Based on the Transformer and High-Resolution Network 被引量:1
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作者 Dengyong Zhang Huaijian Pu +2 位作者 Feng Li Xiangling Ding Victor S.Sheng 《Computers, Materials & Continua》 SCIE EI 2023年第2期3439-3454,共16页
Now object detection based on deep learning tries different strategies.It uses fewer data training networks to achieve the effect of large dataset training.However,the existing methods usually do not achieve the balan... Now object detection based on deep learning tries different strategies.It uses fewer data training networks to achieve the effect of large dataset training.However,the existing methods usually do not achieve the balance between network parameters and training data.It makes the information provided by a small amount of picture data insufficient to optimize model parameters,resulting in unsatisfactory detection results.To improve the accuracy of few shot object detection,this paper proposes a network based on the transformer and high-resolution feature extraction(THR).High-resolution feature extractionmaintains the resolution representation of the image.Channels and spatial attention are used to make the network focus on features that are more useful to the object.In addition,the recently popular transformer is used to fuse the features of the existing object.This compensates for the previous network failure by making full use of existing object features.Experiments on the Pascal VOC and MS-COCO datasets prove that the THR network has achieved better results than previous mainstream few shot object detection. 展开更多
关键词 Object detection few shot object detection TRANSFORMER high-resolution
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High-resolution colonic manometry and its clinical application in patients with colonic dysmotility: A review 被引量:7
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作者 Yu-Wei Li Yong-Jun Yu +2 位作者 Fei Fei Min-Ying Zheng Shi-Wu Zhang 《World Journal of Clinical Cases》 SCIE 2019年第18期2675-2686,共12页
The detailed process and mechanism of colonic motility are still unclear, and colonic motility disorders are associated with numerous clinical diseases. Colonic manometry is considered to the most direct means of eval... The detailed process and mechanism of colonic motility are still unclear, and colonic motility disorders are associated with numerous clinical diseases. Colonic manometry is considered to the most direct means of evaluating colonic peristalsis. Colonic manometry has been studied for more than 30 years;however, the long duration of the examination, high risk of catheterization, huge amount of real-time data, strict catheter sterilization, and high cost of disposable equipment restrict its wide application in clinical practice. Recently, highresolution colonic manometry (HRCM) has rapidly developed into a major technique for obtaining more effective information involved in the physiology and/or pathophysiology of colonic contractile activity in colonic dysmotility patients. This review focuses on colonic motility, manometry, operation, and motor patterns, and the clinical application of HRCM. Furthermore, the limitations, future directions, and potential usefulness of HRCM in the evaluation of clinical treatment effects are also discussed. 展开更多
关键词 high-resolution COLONIC manometry Constipation High-amplitude propulsive CONTRACTIONS LOW-AMPLITUDE propagated CONTRACTIONS COLONIC DYSMOTILITY
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Full Scale-Aware Balanced High-Resolution Network for Multi-Person Pose Estimation
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作者 Shaohua Li Haixiang Zhang +2 位作者 HanjieMa Jie Feng Mingfeng Jiang 《Computers, Materials & Continua》 SCIE EI 2023年第9期3379-3392,共14页
Scale variation is amajor challenge inmulti-person pose estimation.In scenes where persons are present at various distances,models tend to perform better on larger-scale persons,while the performance for smaller-scale... Scale variation is amajor challenge inmulti-person pose estimation.In scenes where persons are present at various distances,models tend to perform better on larger-scale persons,while the performance for smaller-scale persons often falls short of expectations.Therefore,effectively balancing the persons of different scales poses a significant challenge.So this paper proposes a newmulti-person pose estimation model called FSANet to improve themodel’s performance in complex scenes.Our model utilizes High-Resolution Network(HRNet)as the backbone and feeds the outputs of the last stage’s four branches into the DCB module.The dilated convolution-based(DCB)module employs a parallel structure that incorporates dilated convolutions with different rates to expand the receptive field of each branch.Subsequently,the attention operation-based(AOB)module performs attention operations at both branch and channel levels to enhance high-frequency features and reduce the influence of noise.Finally,predictions are made using the heatmap representation.The model can recognize images with diverse scales and more complex semantic information.Experimental results demonstrate that FSA Net achieves competitive results on the MSCOCO and MPII datasets,validating the effectiveness of our proposed approach. 展开更多
关键词 Computer vision high-resolution network human pose estimation
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Evaluation of Tianji and ECMWF high-resolution precipitation forecasts for extreme rainfall event in Henan in July 2021
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作者 Wen-tao Li Jia-peng Zhang +1 位作者 Ruo-chen Sun Qingyun Duan 《Water Science and Engineering》 EI CAS CSCD 2023年第2期122-131,共10页
The extreme rainfall event of July 17 to 22, 2021 in Henan Province, China, led to severe urban waterlogging and flood disasters. This study investigated the performance of high-resolution weather forecasts in predict... The extreme rainfall event of July 17 to 22, 2021 in Henan Province, China, led to severe urban waterlogging and flood disasters. This study investigated the performance of high-resolution weather forecasts in predicting this extreme event and the feasibility of weather forecast-based hydrological forecasts. To achieve this goal, high-resolution precipitation forecasts from the Tianji weather system and the forecast system of the European Centre for Medium-Range Weather Forecasts (ECMWF) were evaluated with the spatial verification metrics of structure, amplitude, and location. The results showed that Tianji weather forecasts accurately predicted the amplitude of 12-h accumulated precipitation with a lead time of 12 h. The location and structure of the rainfall areas in Tianji forecasts were closer to the observations than ECMWF forecasts. Tianji hourly precipitation forecasts were also more accurate than ECMWF hourly forecasts, especially at lead times shorter than 8 h. The precipitation forecasts were used as the inputs to a hydrological model to evaluate their hydrological applications. The results showed that the runoff forecasts driven by Tianji weather forecasts could effectively predict the extreme flood event. The runoff forecasts driven by Tianji forecasts were more accurate than those driven by ECMWF forecasts in terms of amplitude and location. This study demonstrates that high-resolution weather forecasts and corresponding hydrological forecasts can provide valuable information in advance for disaster warnings and leave time for people to act on the event. The results encourage further hydrological applications of high-resolution weather forecasts, such as Tianji weather forecasts, in the future. 展开更多
关键词 Extreme precipitation high-resolution weather forecast EVALUATION Flood forecasting Spatial forecast verification
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High-Resolution Mass Spectroscopy for Revealing the Charge Storage Mechanism in Batteries: Oxamide Materials as an Example
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作者 Chenyang Zhang Yuan Chen +7 位作者 Kun Fan Guoqun Zhang Jincheng Zou Huichao Dai Yanbo Gao Xiaobo Wang Minglei Mao Chengliang Wang 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2023年第4期195-202,共8页
The pursuit of high-performance electrode materials is highly desired to meet the demand of batteries with high energy and power density.However,a deep understanding of the charge storage mechanism is always challengi... The pursuit of high-performance electrode materials is highly desired to meet the demand of batteries with high energy and power density.However,a deep understanding of the charge storage mechanism is always challenging,which limits the development of advanced electrode materials.Herein,high-resolution mass spectroscopy(HR-MS)is employed to detect the evolution of organic electrode materials during the redox process and reveal the charge storage mechanism,by using small molecular oxamides as an example,which have ortho-carbonyls and are therefore potential electrochemical active materials for batteries.The HR-MS results adequately proved that the oxamides could reversibly store lithium ions in the voltage window of 1.5–3.8 V.Upon deeper reduction,the oxamides would decompose due to the cleavage of the C–N bonds in oxamide structures,which could be proved by the fragments detected by HR-MS,^(1)H NMR,and the generation of NH_(3)after the reduction of oxamide by Li.This work provides a strategy to deeply understand the charge storage mechanism of organic electrode materials and will stimulate the further development of characterization techniques to reveal the charge storage mechanism for developing high-performance electrode materials. 展开更多
关键词 charge storage mechanism high-resolution mass spectroscopy organic batteries organic electrodes oxamides
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A systematic printability study of direct ink writing towards high-resolution rapid manufacturing
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作者 Qingyang Zheng Bin Xie +1 位作者 Zhoulong Xu Hao Wu 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2023年第3期500-517,共18页
Direct ink writing(DIW)holds enormous potential in fabricating multiscale and multi-functional architectures by virtue of its wide range of printable materials,simple operation,and ease of rapid prototyping.Although i... Direct ink writing(DIW)holds enormous potential in fabricating multiscale and multi-functional architectures by virtue of its wide range of printable materials,simple operation,and ease of rapid prototyping.Although it is well known that ink rheology and processing parameters have a direct impact on the resolution and shape of the printed objects,the underlying mechanisms of these key factors on the printability and quality of DIW technique remain poorly understood.To tackle this issue,we systematically analyzed the printability and quality through extrusion mechanism modeling and experimental validating.Hybrid non-Newtonian fluid inks were first prepared,and their rheological properties were measured.Then,finite element analysis of the whole DIW process was conducted to reveal the flow dynamics of these inks.The obtained optimal process parameters(ink rheology,applied pressure,printing speed,etc)were also validated by experiments where high-resolution(<100μm)patterns were fabricated rapidly(>70 mm s^(-1)).Finally,as a process research demonstration,we printed a series of microstructures and circuit systems with hybrid inks and silver inks,showing the suitability of the printable process parameters.This study provides a strong quantitative illustration of the use of DIW for the high-speed preparation of high-resolution,high-precision samples. 展开更多
关键词 direct ink writing extrusion mechanism modelling computational fluid dynamic(CFD) printability process parameters high-resolution printing
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On High-Resolution Entropy-Consistent Flux with Slope Limiter for Hyperbolic Conservation Laws
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作者 Xuan Ren Jianhu Feng +2 位作者 Supei Zheng Xiaohan Cheng Yang Li 《Communications on Applied Mathematics and Computation》 EI 2023年第4期1616-1643,共28页
This paper proposes a new version of the high-resolution entropy-consistent(EC-Limited)flux for hyperbolic conservation laws based on a new minmod-type slope limiter.Firstly,we identify the numerical entropy productio... This paper proposes a new version of the high-resolution entropy-consistent(EC-Limited)flux for hyperbolic conservation laws based on a new minmod-type slope limiter.Firstly,we identify the numerical entropy production,a third-order differential term deduced from the previous work of Ismail and Roe[11].The corresponding dissipation term is added to the original Roe flux to achieve entropy consistency.The new,resultant entropy-consistent(EC)flux has a general and explicit analytical form without any corrective factor,making it easy to compute and a less-expensive method.The inequality constraints are imposed on the standard piece-wise quadratic reconstruction to enforce the pointwise values of bounded-type numerical solutions.We design the new minmod slope limiter as combining two separate limiters for left and right states.We propose the EC-Limited flux by adding this reconstruction data method to the primitive variables rather than to the conservative variables of the EC flux to preserve the equilibrium of the primitive variables.These resulting fluxes are easily applied to general hyperbolic conservation laws while having attractive features:entropy-stable,robust,and non-oscillatory.To illustrate the potential of these proposed fluxes,we show the applications to the Burgers equation and the Euler equations. 展开更多
关键词 Hyperbolic conservation laws Entropy production Entropy-consistent(EC)flux Slope limiter high-resolution entropy-consistent(EC-Limited)flux
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Upper esophageal sphincter abnormalities on high-resolution esophageal manometry and treatment response of type Ⅱ achalasia
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作者 Can-Ze Huang Zai-Wei Huang +3 位作者 Hua-Min Liang Zhen-Jiang Wang Ting-Ting Guo Yu-Ping Chen 《World Journal of Clinical Cases》 SCIE 2020年第4期723-735,共13页
BACKGROUND Little is known about the clinical significance of upper esophageal sphincter(UES)motility disorders and their association with the treatment response of typeⅡachalasia.None of the three versions of the Ch... BACKGROUND Little is known about the clinical significance of upper esophageal sphincter(UES)motility disorders and their association with the treatment response of typeⅡachalasia.None of the three versions of the Chicago Classification of Esophageal Motility Disorders has defined UES abnormality metrics or their function.UES abnormalities exist in some patients and indicate a clinically significant problem in patients with achalasia.AIM To demonstrate the manometric differentiation on high-resolution esophageal manometry between subjects with abnormal UES and normal UES,and the association between UES type and the treatment response of typeⅡachalasia.METHODS In total,498 consecutive patients referred for high-resolution esophageal manometry were analyzed retrospectively.The patients were divided into two groups,those with normal and abnormal UES function.UES parameters were analyzed after determining lower esophageal sphincter(LES)function.Patients with typeⅡachalasia underwent pneumatic dilation for treatment.Using mixed model analyses,correlations between abnormal UES and treatment response were calculated among subjects with typeⅡachalasia.RESULTS Of the 498 consecutive patients,246(49.40%)were found to have UES abnormalities.Impaired relaxation alone was the most common UES abnormality(52.85%,n=130).The incidence rate of typeⅡachalasia was significantly higher in subjects with abnormal UES than those with normal UES(9.77%vs 2.58%,P=0.01).After pneumatic dilation,LES resting pressure,LES integrated relaxation pressure,and UES residual pressure were significantly decreased(41.91±9.20 vs 26.18±13.08,38.94±10.28 vs 16.71±5.65,and 11.18±7.93 vs 5.35±4.77,respectively,P<0.05).According to the Eckardt score,subjects with typeⅡachalasia and abnormal UES presented a significantly poorer treatment response than those with normal UES(83.33%vs 0.00%,P<0.05).CONCLUSION Impaired relaxation alone is the most common UES abnormality.The incidence of typeⅡachalasia is associated with abnormal UES.TypeⅡachalasia with abnormal UES has a poorer treatment response,which is a potentially prognostic indicator of treatment for this disease. 展开更多
关键词 Upper esophageal sphincter high-resolution esophageal manometry ACHALASIA Treatment response
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Semi-Solid and Solid Bolus Swallows in High-Resolution Oesophageal Manometry for the Detection of Motility Disorders
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作者 Jerry Zhou Catherine Sykes Vincent Ho 《Open Journal of Gastroenterology》 2018年第1期1-16,共16页
Background/Aims: High-resolution oesophageal manometry utilises water swallows to evaluate oesophageal function. However, small volumes of water are not representative of normal eating and as a result often produce no... Background/Aims: High-resolution oesophageal manometry utilises water swallows to evaluate oesophageal function. However, small volumes of water are not representative of normal eating and as a result often produce normal manometry studies in patients with dysphagia. This study sets out to establish optimal diagnostic thresholds for semi-solid solid swallows and evaluate their ability to uncover motility abnormalities in patients with motility disorders. Method: Manometry was performed using ten 5-mL single water swallows followed by two semi-solid and two solid swallows in the upright position. Normative values for the adjunctive tests were obtained from patient controls while patients with major motility disorders were used to establish the optimal diagnostic thresholds. Diagnostic thresholds identified were prospectively tested in patients with normal water swallows but oesophagus related symptoms and in those with minor and major motility disorders. Results: Normal values for semi-solid and solid were determined in patient controls (n = 100). Development of diagnostic thresholds included 120 patients with major motility disorders. Optimal diagnostic thresholds identified for oesophagogastric junction dysfunction in semi-solid and solid swallows (IRP > 15.5 mmHg). Hypercontractilty and spasm used existing thresholds (>8000 mmHg-s-cm and < 4.5 s, respectively) but modified frequency of ≥50% of adjunctive swallows. Diagnostic thresholds were applied to symptomatic patients with normal water swallows (n = 70) identifying 12/70 (17%) to have abnormal adjunctive swallows. One of 30 patients (3%) with ineffective motility had abnormal adjunctive swallow and 12 patients with oesophageal spasm, oesophagogastric junction obstruction, and hypercontractility had abnormal adjunctive swallows that moved them up the motility disorder hierarchy. Conclusions: Semi-solid and solid challenge increase diagnostic yield of motility disorders. 展开更多
关键词 high-resolution manometry OESOPHAGUS Motility Diagnostic Classification BOLUS Type
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High-Resolution Esophageal Manometry in Teenagers with Esophageal Atresia
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作者 Cecilia Zubiri Rosa Ramos +20 位作者 Cecilia Curvale Raúl Matanó Paula Borobia Anabella Zosi Verónica Garrido Julieta Hernández Lucía Gutierrez Luciana Guzmán María Cristina Arregui Marina Prozzi Sandro Miculan Viviana Bernedo Maximiliano Fernández Rivas Cristina Lorenzo Florencia Recalde Verónica Valdiviezo Darío Fajre Cintia Antonioli Mariana Allende Claudia Losada Teresita Gonzalez 《Open Journal of Epidemiology》 2020年第1期81-89,共9页
Introduction: Children with surgically repaired esophageal atresia (EA) show esophageal dysmotility. Due to the performance of high-resolution manometry (HRM), three motility alteration patterns have been described, w... Introduction: Children with surgically repaired esophageal atresia (EA) show esophageal dysmotility. Due to the performance of high-resolution manometry (HRM), three motility alteration patterns have been described, which allowed to know the segmental alterations. Objective: To describe the esophageal motility patterns found through HRM in teenagers with EA and to relate these with the associated esophageal pathology and its severity. Materials and Method: Ten teenagers were included with no history of esophageal blockage or dilations in the last six months, who were orally fed and asymptomatic. Through performance of HRM, we found surgical and endoscopic history, as well as of esophageal biopsies and pH monitoring. Results: We found the following patterns: aperistalsis, pressurization and distal contraction. 70% showed distal contraction, and 100% of esophageal endoscopies and biopsies were normal. 57% of the esophageal pH monitoring analyzed was pathologic. In the pressurization and aperistalsis groups, we observed severe esophagitis and requirement of Nissen antireflux procedure in 100% of the cases. Esophageal pH monitoring analyzed was 100% pathologic. Conclusion: We described the esophageal segmental alterations in teenagers with atresia by means of HRM. The distal contraction group showed better development, without severe esophagitis or requirement of antireflux procedure. Therefore, by performing an HRM in teenagers with EA, we could predict the future esophageal behavior, according to the peristaltic pattern, since there are significant differences among the groups in study. 展开更多
关键词 high-resolution manometry ESOPHAGEAL ATRESIA TEENAGERS
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Projection of Future Precipitation Change over China with a High-Resolution Global Atmospheric Model 被引量:40
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作者 冯蕾 周天军 +1 位作者 吴波 Tim LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2011年第2期464-476,共13页
Projections of future precipitation change over China are studied based on the output of a global AGCM, ECHAM5, with a high resolution of T319 (equivalent to 40 km). Evaluation of the model’s performance in simulat... Projections of future precipitation change over China are studied based on the output of a global AGCM, ECHAM5, with a high resolution of T319 (equivalent to 40 km). Evaluation of the model’s performance in simulating present-day precipitation shows encouraging results. The spatial distributions of both mean and extreme precipitation, especially the locations of main precipitation centers, are reproduced reasonably. The simulated annual cycle of precipitation is close to the observed. The performance of the model over eastern China is generally better than that over western China. A weakness of the model is the overestimation of precipitation over northern and western China. Analyses on the potential change in precipitation projected under the A1B scenario show that both annual mean precipitation intensity and extreme precipitation would increase significantly over southeastern China. The percentage increase in extreme precipitation is larger than that of mean precipitation. Meanwhile, decreases in mean and extreme precipitation are evident over the southern Tibetan Plateau. For precipitation days, extreme precipitation days are projected to increase over all of China. Both consecutive dry days over northern China and consecutive wet days over southern China would decrease. 展开更多
关键词 future precipitation change high-resolution AGCM simulation extreme precipitation
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A Comparison Study of Tropical Pacific Ocean State Estimation:Low-Resolution Assimilation vs.High-Resolution Simulation 被引量:5
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作者 符伟伟 朱江 +1 位作者 周广庆 王会军 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2005年第2期212-219,共8页
A comparison study is performed to contrast the improvements in the tropical Pacific oceanic state of a low-resolution model respectively via data assimilation and by an increase in horizontal resolution. A low resolu... A comparison study is performed to contrast the improvements in the tropical Pacific oceanic state of a low-resolution model respectively via data assimilation and by an increase in horizontal resolution. A low resolution model (LR) (1°lat by 2°lon) and a high-resolution model (HR) (0.5°lat by 0.5°lon) are employed for the comparison. The authors perform 20-yr numerical experiments and analyze the annual mean fields of temperature and salinity. The results indicate that the low-resolution model with data assimilation behaves better than the high-resolution model in the estimation of ocean large-scale features. From 1990 to 2000, the average of HR's RMSE (root-mean-square error) relative to independent Tropical Atmosphere Ocean project (TAO) mooring data at randomly selected points is 0.97℃ compared to a RMSE of 0.56℃ for LR with temperature assimilation. Moreover, the LR with data assimilation is more frugal in computation. Although there is room to improve the high-resolution model, the low-resolution model with data assimilation may be an advisable choice in achieving a more realistic large-scale state of the ocean at the limited level of information provided by the current observational system. 展开更多
关键词 comparison study high-resolution model data assimilation low-resolution model
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