In view of the fact that Asians have higher abdominal fat at lower levels of body mass index (BMI), measures of abdominal adiposity such as waist circumference (WC) and waist to hip ratio (WHR) were investigated as pr...In view of the fact that Asians have higher abdominal fat at lower levels of body mass index (BMI), measures of abdominal adiposity such as waist circumference (WC) and waist to hip ratio (WHR) were investigated as predictors of hypertension. Data on BMI, WC, WHR and blood pressure (BP) were recorded through a cross-sectional study on 419 urban adults (210 men and 209 women;aged 30-60 years) in Pune, India. Abdominal obesity was higher among women than men (35.9% vs. 32.4%). However, age adjusted mean systolic BP (124.3 ± 15.1 mmHg vs. 114.7 ± 17.2 mmHg), diastolic BP (82.9 ± 10.5 mmHg vs. 76.4 ± 10.7 mmHg) and prevalence of hypertension (34.3% vs. 21.5%) was significantly higher (p < 0.01) among men than among women. Although both WC and WHR increased with increase in BMI, correlation coefficient of BMI with WC was significantly (p < 0.01) higher than that with WHR in both sexes, suggesting that WC could be better for assessing adiposity. In men, odds ratio [OR (95% CI) = 2.19 (1.08-4.45)] for hypertension was significant (p < 0.05) only for those in highest tertile of WC while it was significant (p < 0.01) even in the middle tertile in case of women [8.24 (2.67-25.43) for higher and 5.71 (1.82-17.89) for middle tertile]. Optimal cutoff for identifying obesity and hypertension showed significant (p < 0.01) area under curve (AUC) and sensitivity for WC than WHR in both sexes. The risk cutoffs were lower compared to those proposed by the World Health Organization especially for men, but were comparable with reported Asian studies. Thus, it was evident that WC performed better than BMI and WHR for assessing the risk of hypertension and may be used as a simple, convenient and inexpensive screening tool in epidemiological studies.展开更多
目的:探讨肥胖与青少年腰椎间盘突出症发病关系。方法:2018年1月至2019年7月经排除标准筛选后,581例接受手术治疗的腰椎间盘突出症患者纳入研究,其中男337例,女244例。按照联合国世界卫生组织对年龄的划分标准将其分为两组,青少年组235...目的:探讨肥胖与青少年腰椎间盘突出症发病关系。方法:2018年1月至2019年7月经排除标准筛选后,581例接受手术治疗的腰椎间盘突出症患者纳入研究,其中男337例,女244例。按照联合国世界卫生组织对年龄的划分标准将其分为两组,青少年组235例,男145例,女90例,年龄14~44(32.2±7.3)岁;中老年组346例,男192例,女154例,年龄45~85(58.7±9.8)岁。入院时由同一名经过培训的调查员用卷尺测量身高、腰围、臀围,电子称测量体重。所有数据测量2次取平均值。计算得出体重指数(body mass index,BMI)和腰臀比。根据各个参数标准将患者分为正常、超重、肥胖,计算不同年龄组各个参数肥胖者的比例,并进行统计学分析。结果:青少年患者中BMI、腰围、腰臀比正常者分别为78例(33.2%),91例(38.7%),85例(36.2%);超重者分别为104例(44.3%),95例(40.4%),99例(42.1%);肥胖者分别为53例(22.5%),49例(20.9%),51例(21.7%)。中老年患者BMI、腰围、腰臀比正常者分别为145例(41.9%),138例(39.9%),147例(42.5%);超重者分别为153例(44.2%),162例(46.8%),155例(44.8%);肥胖者分别为48例(13.9%),46例(13.3%),44例(12.7%)。青少年组3个参数中肥胖者比例均高于中老年组(P<0.05)。结论:肥胖可能额外增加了青少年腰椎间盘的负荷,加速了腰椎退变,对于青少年来说肥胖是腰椎间盘突出症更为显著的危险因素,因此在青少年中控制体重、预防肥胖对减少腰椎间盘突出症的发生率更为重要。展开更多
文摘In view of the fact that Asians have higher abdominal fat at lower levels of body mass index (BMI), measures of abdominal adiposity such as waist circumference (WC) and waist to hip ratio (WHR) were investigated as predictors of hypertension. Data on BMI, WC, WHR and blood pressure (BP) were recorded through a cross-sectional study on 419 urban adults (210 men and 209 women;aged 30-60 years) in Pune, India. Abdominal obesity was higher among women than men (35.9% vs. 32.4%). However, age adjusted mean systolic BP (124.3 ± 15.1 mmHg vs. 114.7 ± 17.2 mmHg), diastolic BP (82.9 ± 10.5 mmHg vs. 76.4 ± 10.7 mmHg) and prevalence of hypertension (34.3% vs. 21.5%) was significantly higher (p < 0.01) among men than among women. Although both WC and WHR increased with increase in BMI, correlation coefficient of BMI with WC was significantly (p < 0.01) higher than that with WHR in both sexes, suggesting that WC could be better for assessing adiposity. In men, odds ratio [OR (95% CI) = 2.19 (1.08-4.45)] for hypertension was significant (p < 0.05) only for those in highest tertile of WC while it was significant (p < 0.01) even in the middle tertile in case of women [8.24 (2.67-25.43) for higher and 5.71 (1.82-17.89) for middle tertile]. Optimal cutoff for identifying obesity and hypertension showed significant (p < 0.01) area under curve (AUC) and sensitivity for WC than WHR in both sexes. The risk cutoffs were lower compared to those proposed by the World Health Organization especially for men, but were comparable with reported Asian studies. Thus, it was evident that WC performed better than BMI and WHR for assessing the risk of hypertension and may be used as a simple, convenient and inexpensive screening tool in epidemiological studies.
文摘目的:探讨肥胖与青少年腰椎间盘突出症发病关系。方法:2018年1月至2019年7月经排除标准筛选后,581例接受手术治疗的腰椎间盘突出症患者纳入研究,其中男337例,女244例。按照联合国世界卫生组织对年龄的划分标准将其分为两组,青少年组235例,男145例,女90例,年龄14~44(32.2±7.3)岁;中老年组346例,男192例,女154例,年龄45~85(58.7±9.8)岁。入院时由同一名经过培训的调查员用卷尺测量身高、腰围、臀围,电子称测量体重。所有数据测量2次取平均值。计算得出体重指数(body mass index,BMI)和腰臀比。根据各个参数标准将患者分为正常、超重、肥胖,计算不同年龄组各个参数肥胖者的比例,并进行统计学分析。结果:青少年患者中BMI、腰围、腰臀比正常者分别为78例(33.2%),91例(38.7%),85例(36.2%);超重者分别为104例(44.3%),95例(40.4%),99例(42.1%);肥胖者分别为53例(22.5%),49例(20.9%),51例(21.7%)。中老年患者BMI、腰围、腰臀比正常者分别为145例(41.9%),138例(39.9%),147例(42.5%);超重者分别为153例(44.2%),162例(46.8%),155例(44.8%);肥胖者分别为48例(13.9%),46例(13.3%),44例(12.7%)。青少年组3个参数中肥胖者比例均高于中老年组(P<0.05)。结论:肥胖可能额外增加了青少年腰椎间盘的负荷,加速了腰椎退变,对于青少年来说肥胖是腰椎间盘突出症更为显著的危险因素,因此在青少年中控制体重、预防肥胖对减少腰椎间盘突出症的发生率更为重要。
