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现代中国针灸学的三大突破性进展 被引量:9
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作者 王永洲 《中国针灸》 CAS CSCD 北大核心 2002年第6期420-422,共3页
实验针灸学、全息针灸学、针刀学是3个自成体系的新学派,它们都是近年来在针灸学的基础上发展建立起来的,在理论上都保持鲜明的自我特征,又主动融入大量现代科学的成分和方法,理论上越来越清晰,具有可持续发展的潜力;实践的精准性也有... 实验针灸学、全息针灸学、针刀学是3个自成体系的新学派,它们都是近年来在针灸学的基础上发展建立起来的,在理论上都保持鲜明的自我特征,又主动融入大量现代科学的成分和方法,理论上越来越清晰,具有可持续发展的潜力;实践的精准性也有所提高,各自都已形成比较成熟的手段与方法,具有可操作性及可重复性。笔者认为这3个学派及其衍化的子系统将构筑真正意义上的现代针灸学的主要框架,逐步与现代科学相接轨,为我们研究针灸学提供了丰富的思路和可行的方法,对整个针灸学的创新和发展有示范推动作用。 展开更多
关键词 针灸学 发展趋势 实验针灸学 小刀针 全息针灸学
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香豆素-4-乙酰苄肼类抗结核病药物的3D-QSAR研究 被引量:1
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作者 仝建波 陈洋 +2 位作者 徐夏梦 杜经武 程芳玲 《陕西科技大学学报(自然科学版)》 2012年第6期57-60,共4页
采用三维全息原子场作用矢量(3D-HoVAIF)对25个香豆素-4-乙酰苄肼类抗结核病药物进行定量构效关系(QSAR)研究.运用多元线性回归(MLR)和偏最小二乘回归(PLS)建模,同时采用内部及外部双重验证的办法对所得模型稳定性能进行了深入分析和检... 采用三维全息原子场作用矢量(3D-HoVAIF)对25个香豆素-4-乙酰苄肼类抗结核病药物进行定量构效关系(QSAR)研究.运用多元线性回归(MLR)和偏最小二乘回归(PLS)建模,同时采用内部及外部双重验证的办法对所得模型稳定性能进行了深入分析和检验.MLR建模和PLS建模的复相关系数(Rcum)、留一法交互校验复相关系数(QLOO)以及外部样本校验复相关系数(Qext)分别为0.926、0.819、0.805和0.919、0.828、0.836.结果表明,3D-HoVAIF能较好表征抗结核药物分子结构信息,所建QSAR模型具有良好稳定性和预测能力,为抗结核病药物的研发提供一定的理论基础. 展开更多
关键词 三维全息原子场作用矢量 香豆素-4-乙酰苄肼类抗结核病药物 定量构效关系
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Effects of nape acupuncture combined with swallowing rehabilitation on dysphagia in pseudobulbar palsy 被引量:10
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作者 Liu Xiaoping Chen Feiyu +1 位作者 Chu Jiamei Bao Yehua 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2018年第1期117-124,共8页
OBJECTIVE: To evaluate the therapeutic effects of nape acupuncture combined with rehabilitative swallowing training for dysphagia caused by pseudobulbar palsy, and to compare it with rehabilitative swallowing training... OBJECTIVE: To evaluate the therapeutic effects of nape acupuncture combined with rehabilitative swallowing training for dysphagia caused by pseudobulbar palsy, and to compare it with rehabilitative swallowing training alone, and to observe the improvement in quality of life after the therapy.METHODS: One hundred patients were randomly divided into two groups: the rehabilitative swallowing training group(control group, n = 50) and the nape acupuncture combined with rehabilitative swallowing training group(experimental group,n = 50). Each group had 8 weeks' therapy, 5 times a week. Patients in the control group received rehabilitative swallowing training, while those in the experimental group received nape acupuncture therapy based on swallowing rehabilitation. The out-comes were assessed by the repetitive saliva-swallowing test(RSST), water swallow test(WST), standardized swallowing assessment(SSA), and a swallow quality-of-life questionnaire(SWAL-QOL). Correlations of onset age, onset frequency and lesion location with the efficacy of the acupuncture treatment were also observed.RESULTS: The scores for RSST, WST, and SSA in both groups were lower than before the therapy(P <0.001), although the changes were more marked in the experimental group than in the control group(RSST and WST, P < 0.005; SSA, P < 0.001). Both groups recorded changes in SWAL-QOL index after the therapy(P < 0.001); and the experimental group scored higher than the control group(P < 0.001). The efficacy of acupuncture was not correlated with location(P > 0.05), but was related to onset age(P < 0.05) and onset frequency(P < 0.01).CONCLUSION: Nape acupuncture combined with rehabilitative swallowing training has an effect on dysphagia caused by pseudobulbar palsy and improves quality of life. 展开更多
关键词 Deglutition disorders Pseudobulbar palsy Quality of life Age of onset Nape acupunc- ture Rehabilitative swallowing training
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