Ships usually operate in the vibrant and dynamic environment;a majority of crews work and have a rest in a stressful space and have daily job displacements that working in it and moving from port disrupt as soon as re...Ships usually operate in the vibrant and dynamic environment;a majority of crews work and have a rest in a stressful space and have daily job displacements that working in it and moving from port disrupt as soon as reaching to port. Such conditions which require living at work place for a long time raises a unique job life which causes increase in risks of human mistakes. Huge marine accidents occur per year in country in which human element plays a major role. Identification and analysis of the components affect individuals as the staffs in ships, so that such component raises the conditions due to inattention which result in rise of severe and more severe marine accidents. Evaluation of each component has been taken into account in the present research. The present research seeks to examine and identity factors affecting human elements in marine accidents.展开更多
In radiotherapy, the energy of the γ rays used could be larger than 10 Me V, which would potentially activate stable nucleus into a radioactive one. The γ induced reactions on some of the human essential elements ar...In radiotherapy, the energy of the γ rays used could be larger than 10 Me V, which would potentially activate stable nucleus into a radioactive one. The γ induced reactions on some of the human essential elements are studied to show the probability of changes of nuclei. The Talys 1.4 toolkit was adopted as the theoretical model for calculation. The reactions investigated include the(γ, n) and(γ, p) channels for the stable Na, Mg, Cl,K, Ca, and Fe isotopes, with the incident energy of γ ranging from 1 to 30 Me V. It was found that the cross sections for the reactions are very low, and the maximum cross section is no larger than 100 mb. By considering the threshold energy of the channel, the half-life time of the residue nucleus, and the percentage of the element accounting for the weight and its importance in the body, it is suggested to track the radioactive nuclei22 Na,41Ca, and42,43 K after γ therapy. The results might be useful for medical diagnosis and disease treatment.展开更多
September 2017 Contents Preface Ensuring People’s Right to Health Based on China’s Conditions Continuous Improvement of Health Environment and Conditions Public Health Service Capability Improving Steadily Great Imp...September 2017 Contents Preface Ensuring People’s Right to Health Based on China’s Conditions Continuous Improvement of Health Environment and Conditions Public Health Service Capability Improving Steadily Great Improvement in the Quality of Medical and Health Services Improvement of the National Medical Security System展开更多
Twenty four male autopsies were obtained from Shanghai. The samples of liver, lung, kidney cortex, brain and scalp hair were collected from the autopsies. The elements As, Br, Ca, Cd, Cl, Co, Cr, Cu, Fe, Hg, Mg, Mn, N...Twenty four male autopsies were obtained from Shanghai. The samples of liver, lung, kidney cortex, brain and scalp hair were collected from the autopsies. The elements As, Br, Ca, Cd, Cl, Co, Cr, Cu, Fe, Hg, Mg, Mn, Na, Rb, 8, Se and Zn were determined by neutron activation analysis (NAA). The present study provides the elemental levels of different tissues for normal male adults. The distribution pattern of elements was discussed. Great difference on distribution of some elements in different tissues was observed.展开更多
Reference values reflecting the findings of natural concentrations of teeth in a well-defined group of individuals, are indispensable, if one is to interpret results generated for clinical utility. Hence, a comprehens...Reference values reflecting the findings of natural concentrations of teeth in a well-defined group of individuals, are indispensable, if one is to interpret results generated for clinical utility. Hence, a comprehensive compilation of literature survey is attempted to make available as a reference guideline for tooth element concentrations. Presently, the reference values are proposed for 19 elements. Several factors that are found influencing element levels, are common to any biosample and are broadly grouped under four categories namely, the factors of teeth, donor, environment and analytical methods. How best the influencing factors to be considered during analysis, are discussed. It is elucidated that standardized method of analysis with quality assurance and precision will reduce the ambiguity of comparison of inter-laboratory measurement. When the merits and demerits of element measurements are evaluated, it is recognized that except a hurdle of difficult specific sampling, many advantages make teeth an attractive material for environmental health monitoring of population and for assessment of element status of deficiency and excess due to differential exposure. The available data of tooth elements are lesser in comparison to data of blood and hair;further studies are required for reference values of others elements and for distribution pattern in different conditions, parts and types of teeth.展开更多
Trace elements constitute less than 1% of the rocks in the crust (Stumm and Morgan, 1991). In the human body, they constitute less than 100 mg/kg (0.01%). These elements are released to the environment naturally by we...Trace elements constitute less than 1% of the rocks in the crust (Stumm and Morgan, 1991). In the human body, they constitute less than 100 mg/kg (0.01%). These elements are released to the environment naturally by weathering and volcanic activities (Flint and skinner, 1997). It has been observed that trace elements are greatly absorbed and retained in the body when in liquid diet. This phenomenon also influences the risk to human health, especially of infants and children whose immature digestive system further promote absorption of toxic heavy metals. The study was based on the analysis of domestic borehole water supplies in Huruma estate of Eldoret Municipality for selected trace elements and their implications on human health. The boreholes were systematically selected for sampling points and trace elements, Cr, Cu and Se analyzed using AAS. Statistical analysis for mean, standard deviation and confidence interval limits was done using SPSS. The statistical t-test was used to test for significance differences at (p = 0.05). The graphs were drawn using the Microsoft Excel package. The resulting data obtained from analysis were compared with WHO data for drinking water. In the study, the mean values of the following parameters were as follows: Chromium 17.9 μg/L, Copper 563 μg/L and Selenium 22.7 μg/L. There was a significant difference at 5% level of significance (p = 0.000) in all the parameter values among the sampling points in Huruma estate. The above mean values were far below the WHO recommended limits for drinking water. It was concluded that the borehole water from Huruma was fit for drinking and therefore could not cause cancer and cardiovascular diseases. However, borehole water should be used if other water sources (tap water etc.) were not available. All the industries near Huruma estate should carefully analyze and regularly monitor their liquid waste effluents to ensure that no harmful discharges get into the soil.展开更多
This paper deals with the determination of trace elements in normal human hair, liver and kidney by Proton Induced X-ray Emission (PIXE) analysis. Sampling, specimen preparation and experimental procedures are describ...This paper deals with the determination of trace elements in normal human hair, liver and kidney by Proton Induced X-ray Emission (PIXE) analysis. Sampling, specimen preparation and experimental procedures are described in detail. The accuracy of our system has been checked up with the determination of standard reference materials. The preliminary results on correlations between trace elements in human tissues are discussed. Application of the method described in the paper gives evidence in favour of the PIXE as a good tool on environmental life elements and health studies.展开更多
A direct and simple method for the clinic muti-element determination of human blood sample by Zeeman graphite furnace atomic absorption spectropho-tometry is reported. No pretreatment of the sample is necessary other ...A direct and simple method for the clinic muti-element determination of human blood sample by Zeeman graphite furnace atomic absorption spectropho-tometry is reported. No pretreatment of the sample is necessary other than simple dilution of the sample with aqueous solution of Triton X-100. The detection limits of the elements investigated fall in the range of 0.1- 4.4 μg/L with a relative standard deviation ranging from 1.6 for zinc to 3.73% for lead. Micro liters of samples are sufficient for the determination of each element.展开更多
A human middle ear consists of an eardrum and three ossicles which are linked by each other, and connect with the eardrum and an inner ear. The inner ear consists of a cochlea and a vestibular system. An abnormality o...A human middle ear consists of an eardrum and three ossicles which are linked by each other, and connect with the eardrum and an inner ear. The inner ear consists of a cochlea and a vestibular system. An abnormality of the human middle ear such as ossicular dislocation may cause conductive hearing loss. The conductive hearing loss is generally treated by surgery using artificial ossicles. The treatments of conductive hearing loss require a better understanding of characteristics and dynamic behaviors of the human middle ear when the sounds transmit from outer inner to inner ear. The purpose of this research is to simulate the dynamic behaviors of a human ear system comprising the middle ear and the cochlea in the inner ear using the finite element method (FEM). Firstly, the eigen-value analysis was performed to obtain the natural frequencies and vibration modes of the total ear system. Secondly, the frequency response analysis was carried out. Thirdly, the time history response analyses were performed using human voices as the external forces. In the time history response analyses, the sounds created as input sound pressures were used. Human voices, for example vowels “I”, “u” and “e” as input sound pressures were created by using the sound pressures downloaded from the opening samples of human voices as wav files in a website. Then it was clarified that the high frequency components of sounds are reduced by the middle ear system.展开更多
In public health studies limited volumes of blood are often collected and stored for future hypothesis testing. Archived samples are irreplaceable and therefore it is valuable to develop analytical techniques that req...In public health studies limited volumes of blood are often collected and stored for future hypothesis testing. Archived samples are irreplaceable and therefore it is valuable to develop analytical techniques that require minimal sample vo-lume. This work describes the measurement of trace elements Mg, Cu, Fe, Zn and ultratrace elements Cd, Co, Mn, Pb in limited quantity (150 μL) human serum or plasma samples. Samples were digested using a hotblock and analyzed using inductively coupled plasma mass spectrometry (ICP-MS). The analytical method was evaluated using a quadrupole (Q) and sector field high resolution (SF) instrument to analyze trace elements in Seronorm? quality control serum material. The method was used to analyze 1888 blinded human plasma samples which were archived for the National Cancer Institute from the Nutrition Intervention Trial in Linxian China. The inductively coupled plasma method was capable of accurately analyzed limited quantity samples of human serum and plasma for the trace elements Mg, Cu, Fe Zn and the ultra trace elements Co, Mn and Pb. The concentration of Cd in human plasma samples was below the level of detection for 75% of the samples analyzed.展开更多
The analysis of trace elements in human hair for use as biomarkers continues to generate considerable interest in environmental and bioanalytical studies, medical diagnostics, and forensic science. This study investig...The analysis of trace elements in human hair for use as biomarkers continues to generate considerable interest in environmental and bioanalytical studies, medical diagnostics, and forensic science. This study investigated the concentrations of essential and toxic elements (Fe, Mg, Ca, Cu, Zn, Cr, Cd, and Pb) using flame atomic absorption spectroscopy (FAAS) in human scalp hair obtained from subjects living in Forsyth County, North Carolina, USA. The influence of age, sex, race, and smoking habits on the levels of trace elements in the hair samples were also investigated. Additionally, analyses were subjected to a statistical, regression, and principal component analysis to evaluate inter-elemental association and possible pattern recognition in hair samples. Furthermore, Ca/Mg and Zn/Cu ratios, which are often used to evaluate the degree of Ca and Cu utilization in humans and as markers for various health related issues including, atherosclerosis, hypertension, insulin sensitivity, and pancreatic cancer, were calculated. The overall mean concentrations of Fe (25 μg/g), Ca (710 μg/g), Mg (120 μg/g), Zn (190 μg/g), Cu (12 μg/g), and Cr (0.20 μg/g) were found in hair samples. The trace element concentrations varied widely in hair samples as demonstrated by large range of concentrations obtained for each element. However, levels of Cd and Pb elements of <0.030 μg/g were detected in hair sample. In general, the levels of the trace elements in hair samples were poorly correlated. However, significant correlations were found between Ca and Mg (r = 0.840, p = 0.05). The levels of Fe, Ca, Mg, Zn, Cu, and Cr in hair samples and the calculated Ca/Mg and Zn/Cu ratios were found to be largely correlated with age, race, sex, and smoking habits.展开更多
In this paper we present the Projection Based Interpolation (PBI) technique for construction of continuous approximation of MRI scan data of the human head. We utilize the result of the PBI algorithm to perform three ...In this paper we present the Projection Based Interpolation (PBI) technique for construction of continuous approximation of MRI scan data of the human head. We utilize the result of the PBI algorithm to perform three dimensional (3D) Finite Element Method (FEM) simulations of the acoustics of the human head. The computational problem is a multi-physics problem modeled as acoustics coupled with linear elasticity. The computational grid contains tetrahedral finite elements with the number of equations and polynomial orders of approximation varying locally on finite element edges, faces, and interiors. We utilize our own out-of-core parallel direct solver for the solution of this multi-physics problem. The solver minimizes the memory usage by dumping out all local systems from all nodes of the entire elimination tree during the elimination phase.展开更多
Coal is the most abundant fossil fuel in the world. Because of the growth of coal mining, coal-fired power plants and coal-burning industries, the increase of the emission of particulates(coarse, fine or ultrafine)is ...Coal is the most abundant fossil fuel in the world. Because of the growth of coal mining, coal-fired power plants and coal-burning industries, the increase of the emission of particulates(coarse, fine or ultrafine)is of great concern. There is a relationship between increasing human morbidity and mortality and progressive environmental air pollution caused by these types of particles. Thus, the knowledge of the physico-chemical composition and ambient concentrations of coal-derived nanoparticles will improve pollution control strategy. Given the current importance of this area of research, the advanced characterization of this coal combustion-derived nanoparticles/nanominerals as well as hazardous elements is likely to be one of the hottest research fields in coming days. In this review, we try to compile the existing knowledge on coal-derived nanoparticles/nanominerals and discuss the advanced level of characterization techniques for future research. This review also provides some of aspects of health risks associated with exposure to ambient nanoparticles. In addition, the presence of some of the hazardous elements in coal and coal combustion activities is also reviewed.展开更多
A nondestructive instrumental neutron activation analysis with high-resolution gamma-ray spectrometry of long-lived radionuclides was developed and used for measurement of trace element contents in samples of bone to ...A nondestructive instrumental neutron activation analysis with high-resolution gamma-ray spectrometry of long-lived radionuclides was developed and used for measurement of trace element contents in samples of bone to determine health and diseases. Using this method, the silver(Ag), cobalt(Co), chromium(Cr), iron(Fe), mercury(Hg), rubidium(Rb), antimony(Sb), selenium(Se), and zinc(Zn) mass fractions were estimated in bone samples from 27 patients with intact bone(12 females and 15 males, aged from 16 to 49 years) who had died from various non-bone-related causes, mainly unexpected traumas,and from 5 patients with chondroma(2 females and 3males, 15–42 years old), obtained from open biopsies or after operation. The reliability of the differences in the results between intact bone and bone affected by chondroma was evaluated by a parametric Student's t test and a nonparametric Mann–Whitney U test. It was found that in the bone affected by chondroma, the mean mass fractions of Co, Cr, Fe, Se, Sb, and Zn were significantly higher than in normal bone tissues. In the neoplastic bone, many correlations between trace elements found in the control group were no longer evident. This work revealed that there is asignificant disturbance of the trace element metabolism in bone affected by chondroma.展开更多
A facility and method for109 Cd radionuclide-induced energy-dispersive X-ray fluorescent(EDXRF) were developed to determine the Fe,Zn,Br,Rb,and Sr concentrations in the specimens of human prostatic fluid.Specimens of ...A facility and method for109 Cd radionuclide-induced energy-dispersive X-ray fluorescent(EDXRF) were developed to determine the Fe,Zn,Br,Rb,and Sr concentrations in the specimens of human prostatic fluid.Specimens of expressed prostatic fluid were obtained from 51 men(mean age 51 years,range 18–82 years) with apparently normal prostates using standard rectal massage procedure.Mean values(M ± SEL) for concentration of trace elements(mg L^(-1)) in human prostate fluid were:Fe 9.04 ±1.21,Zn 573 ± 35,Br 3.58 ± 0.59,Rb 1.10 ± 0.08,and Sr B 0.76.It was shown that the results of trace element analysis in the micro-samples(20 l L) are sufficiently representative for assessment of the Fe,Zn,Br,and Rb concentration in the prostate fluid.The facility for109 Cd radionuclide-induced EDXRF is comparatively compact and can be located in close proximity to the site of carrying out the massage procedure.The means of Zn and Rb concentration obtained for prostate fluid agree well with median of reported means.For the first time,the Fe and Br concentrations,as well as the upper limit of the Sr concentration,were determined in the human prostate fluid.展开更多
The relationship between human and landscape architecture was explored by studying a poem of Bian Zhilin. From the perspectives of social value of landscape architecture, relationship between human and landscape archi...The relationship between human and landscape architecture was explored by studying a poem of Bian Zhilin. From the perspectives of social value of landscape architecture, relationship between human and landscape architecture and integrality of landscape architecture, it was proposed that human was also a component of landscape architecture, and participation of human realized the social value of landscape architecture, moreover, human was a kind of landscape while landscape architecture was regarded as a "drama", thus only landscape architecture used by human was a complete one.展开更多
A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model,...A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model, including lungs. A torso-cardiac vector model is used for a 12-lead electrocardiographic (ECG) and magneto-cardiogram (MCG) simulation study by using the boundary element method (BEM). Also, we obtain the MCG wave picture using a compound four-channel HTc.SQUID system in a magnetically shielded room. By comparing the simulated results and experimental results, we verify the cardiac vector model and then do a preliminary study of the forward problem of MCG and ECG. Therefore, the results show that the vector model is reasonable in cardiac electrophysiology.展开更多
From the perspective of humanized design concepts, humanized space design and behavioral psychological needs of users were re-interpreted and analyzed, basic elements and design principles of cultural plaza spatial la...From the perspective of humanized design concepts, humanized space design and behavioral psychological needs of users were re-interpreted and analyzed, basic elements and design principles of cultural plaza spatial layout were proposed. Particularly, application and role of humanized design in the spatial layout of cultural plaza was analyzed, on the basis of which humanized design objective and orientation for the sustainable development of cultural plaza was defined.展开更多
The preparation of the human hair reference material and the steps taken to confirm its homogeneity and stability as well as its certificatipn are described. Certified values for 17 elements, which are of importance f...The preparation of the human hair reference material and the steps taken to confirm its homogeneity and stability as well as its certificatipn are described. Certified values for 17 elements, which are of importance for human health, and reference values for the other 13 elements are provided for this material.展开更多
文摘Ships usually operate in the vibrant and dynamic environment;a majority of crews work and have a rest in a stressful space and have daily job displacements that working in it and moving from port disrupt as soon as reaching to port. Such conditions which require living at work place for a long time raises a unique job life which causes increase in risks of human mistakes. Huge marine accidents occur per year in country in which human element plays a major role. Identification and analysis of the components affect individuals as the staffs in ships, so that such component raises the conditions due to inattention which result in rise of severe and more severe marine accidents. Evaluation of each component has been taken into account in the present research. The present research seeks to examine and identity factors affecting human elements in marine accidents.
基金Supported by the Plan for Scientific Innovation Talent of Henan Province(PSITHP)the Young Teacher Project at Henan Normal University
文摘In radiotherapy, the energy of the γ rays used could be larger than 10 Me V, which would potentially activate stable nucleus into a radioactive one. The γ induced reactions on some of the human essential elements are studied to show the probability of changes of nuclei. The Talys 1.4 toolkit was adopted as the theoretical model for calculation. The reactions investigated include the(γ, n) and(γ, p) channels for the stable Na, Mg, Cl,K, Ca, and Fe isotopes, with the incident energy of γ ranging from 1 to 30 Me V. It was found that the cross sections for the reactions are very low, and the maximum cross section is no larger than 100 mb. By considering the threshold energy of the channel, the half-life time of the residue nucleus, and the percentage of the element accounting for the weight and its importance in the body, it is suggested to track the radioactive nuclei22 Na,41Ca, and42,43 K after γ therapy. The results might be useful for medical diagnosis and disease treatment.
文摘September 2017 Contents Preface Ensuring People’s Right to Health Based on China’s Conditions Continuous Improvement of Health Environment and Conditions Public Health Service Capability Improving Steadily Great Improvement in the Quality of Medical and Health Services Improvement of the National Medical Security System
文摘Twenty four male autopsies were obtained from Shanghai. The samples of liver, lung, kidney cortex, brain and scalp hair were collected from the autopsies. The elements As, Br, Ca, Cd, Cl, Co, Cr, Cu, Fe, Hg, Mg, Mn, Na, Rb, 8, Se and Zn were determined by neutron activation analysis (NAA). The present study provides the elemental levels of different tissues for normal male adults. The distribution pattern of elements was discussed. Great difference on distribution of some elements in different tissues was observed.
文摘Reference values reflecting the findings of natural concentrations of teeth in a well-defined group of individuals, are indispensable, if one is to interpret results generated for clinical utility. Hence, a comprehensive compilation of literature survey is attempted to make available as a reference guideline for tooth element concentrations. Presently, the reference values are proposed for 19 elements. Several factors that are found influencing element levels, are common to any biosample and are broadly grouped under four categories namely, the factors of teeth, donor, environment and analytical methods. How best the influencing factors to be considered during analysis, are discussed. It is elucidated that standardized method of analysis with quality assurance and precision will reduce the ambiguity of comparison of inter-laboratory measurement. When the merits and demerits of element measurements are evaluated, it is recognized that except a hurdle of difficult specific sampling, many advantages make teeth an attractive material for environmental health monitoring of population and for assessment of element status of deficiency and excess due to differential exposure. The available data of tooth elements are lesser in comparison to data of blood and hair;further studies are required for reference values of others elements and for distribution pattern in different conditions, parts and types of teeth.
文摘Trace elements constitute less than 1% of the rocks in the crust (Stumm and Morgan, 1991). In the human body, they constitute less than 100 mg/kg (0.01%). These elements are released to the environment naturally by weathering and volcanic activities (Flint and skinner, 1997). It has been observed that trace elements are greatly absorbed and retained in the body when in liquid diet. This phenomenon also influences the risk to human health, especially of infants and children whose immature digestive system further promote absorption of toxic heavy metals. The study was based on the analysis of domestic borehole water supplies in Huruma estate of Eldoret Municipality for selected trace elements and their implications on human health. The boreholes were systematically selected for sampling points and trace elements, Cr, Cu and Se analyzed using AAS. Statistical analysis for mean, standard deviation and confidence interval limits was done using SPSS. The statistical t-test was used to test for significance differences at (p = 0.05). The graphs were drawn using the Microsoft Excel package. The resulting data obtained from analysis were compared with WHO data for drinking water. In the study, the mean values of the following parameters were as follows: Chromium 17.9 μg/L, Copper 563 μg/L and Selenium 22.7 μg/L. There was a significant difference at 5% level of significance (p = 0.000) in all the parameter values among the sampling points in Huruma estate. The above mean values were far below the WHO recommended limits for drinking water. It was concluded that the borehole water from Huruma was fit for drinking and therefore could not cause cancer and cardiovascular diseases. However, borehole water should be used if other water sources (tap water etc.) were not available. All the industries near Huruma estate should carefully analyze and regularly monitor their liquid waste effluents to ensure that no harmful discharges get into the soil.
文摘This paper deals with the determination of trace elements in normal human hair, liver and kidney by Proton Induced X-ray Emission (PIXE) analysis. Sampling, specimen preparation and experimental procedures are described in detail. The accuracy of our system has been checked up with the determination of standard reference materials. The preliminary results on correlations between trace elements in human tissues are discussed. Application of the method described in the paper gives evidence in favour of the PIXE as a good tool on environmental life elements and health studies.
文摘A direct and simple method for the clinic muti-element determination of human blood sample by Zeeman graphite furnace atomic absorption spectropho-tometry is reported. No pretreatment of the sample is necessary other than simple dilution of the sample with aqueous solution of Triton X-100. The detection limits of the elements investigated fall in the range of 0.1- 4.4 μg/L with a relative standard deviation ranging from 1.6 for zinc to 3.73% for lead. Micro liters of samples are sufficient for the determination of each element.
文摘A human middle ear consists of an eardrum and three ossicles which are linked by each other, and connect with the eardrum and an inner ear. The inner ear consists of a cochlea and a vestibular system. An abnormality of the human middle ear such as ossicular dislocation may cause conductive hearing loss. The conductive hearing loss is generally treated by surgery using artificial ossicles. The treatments of conductive hearing loss require a better understanding of characteristics and dynamic behaviors of the human middle ear when the sounds transmit from outer inner to inner ear. The purpose of this research is to simulate the dynamic behaviors of a human ear system comprising the middle ear and the cochlea in the inner ear using the finite element method (FEM). Firstly, the eigen-value analysis was performed to obtain the natural frequencies and vibration modes of the total ear system. Secondly, the frequency response analysis was carried out. Thirdly, the time history response analyses were performed using human voices as the external forces. In the time history response analyses, the sounds created as input sound pressures were used. Human voices, for example vowels “I”, “u” and “e” as input sound pressures were created by using the sound pressures downloaded from the opening samples of human voices as wav files in a website. Then it was clarified that the high frequency components of sounds are reduced by the middle ear system.
文摘In public health studies limited volumes of blood are often collected and stored for future hypothesis testing. Archived samples are irreplaceable and therefore it is valuable to develop analytical techniques that require minimal sample vo-lume. This work describes the measurement of trace elements Mg, Cu, Fe, Zn and ultratrace elements Cd, Co, Mn, Pb in limited quantity (150 μL) human serum or plasma samples. Samples were digested using a hotblock and analyzed using inductively coupled plasma mass spectrometry (ICP-MS). The analytical method was evaluated using a quadrupole (Q) and sector field high resolution (SF) instrument to analyze trace elements in Seronorm? quality control serum material. The method was used to analyze 1888 blinded human plasma samples which were archived for the National Cancer Institute from the Nutrition Intervention Trial in Linxian China. The inductively coupled plasma method was capable of accurately analyzed limited quantity samples of human serum and plasma for the trace elements Mg, Cu, Fe Zn and the ultra trace elements Co, Mn and Pb. The concentration of Cd in human plasma samples was below the level of detection for 75% of the samples analyzed.
文摘The analysis of trace elements in human hair for use as biomarkers continues to generate considerable interest in environmental and bioanalytical studies, medical diagnostics, and forensic science. This study investigated the concentrations of essential and toxic elements (Fe, Mg, Ca, Cu, Zn, Cr, Cd, and Pb) using flame atomic absorption spectroscopy (FAAS) in human scalp hair obtained from subjects living in Forsyth County, North Carolina, USA. The influence of age, sex, race, and smoking habits on the levels of trace elements in the hair samples were also investigated. Additionally, analyses were subjected to a statistical, regression, and principal component analysis to evaluate inter-elemental association and possible pattern recognition in hair samples. Furthermore, Ca/Mg and Zn/Cu ratios, which are often used to evaluate the degree of Ca and Cu utilization in humans and as markers for various health related issues including, atherosclerosis, hypertension, insulin sensitivity, and pancreatic cancer, were calculated. The overall mean concentrations of Fe (25 μg/g), Ca (710 μg/g), Mg (120 μg/g), Zn (190 μg/g), Cu (12 μg/g), and Cr (0.20 μg/g) were found in hair samples. The trace element concentrations varied widely in hair samples as demonstrated by large range of concentrations obtained for each element. However, levels of Cd and Pb elements of <0.030 μg/g were detected in hair sample. In general, the levels of the trace elements in hair samples were poorly correlated. However, significant correlations were found between Ca and Mg (r = 0.840, p = 0.05). The levels of Fe, Ca, Mg, Zn, Cu, and Cr in hair samples and the calculated Ca/Mg and Zn/Cu ratios were found to be largely correlated with age, race, sex, and smoking habits.
文摘In this paper we present the Projection Based Interpolation (PBI) technique for construction of continuous approximation of MRI scan data of the human head. We utilize the result of the PBI algorithm to perform three dimensional (3D) Finite Element Method (FEM) simulations of the acoustics of the human head. The computational problem is a multi-physics problem modeled as acoustics coupled with linear elasticity. The computational grid contains tetrahedral finite elements with the number of equations and polynomial orders of approximation varying locally on finite element edges, faces, and interiors. We utilize our own out-of-core parallel direct solver for the solution of this multi-physics problem. The solver minimizes the memory usage by dumping out all local systems from all nodes of the entire elimination tree during the elimination phase.
基金partial financial assistance of Ministry of Environment Forest and Climate Change (MoEFCC), Govt. of India (GPP-0325)
文摘Coal is the most abundant fossil fuel in the world. Because of the growth of coal mining, coal-fired power plants and coal-burning industries, the increase of the emission of particulates(coarse, fine or ultrafine)is of great concern. There is a relationship between increasing human morbidity and mortality and progressive environmental air pollution caused by these types of particles. Thus, the knowledge of the physico-chemical composition and ambient concentrations of coal-derived nanoparticles will improve pollution control strategy. Given the current importance of this area of research, the advanced characterization of this coal combustion-derived nanoparticles/nanominerals as well as hazardous elements is likely to be one of the hottest research fields in coming days. In this review, we try to compile the existing knowledge on coal-derived nanoparticles/nanominerals and discuss the advanced level of characterization techniques for future research. This review also provides some of aspects of health risks associated with exposure to ambient nanoparticles. In addition, the presence of some of the hazardous elements in coal and coal combustion activities is also reviewed.
文摘A nondestructive instrumental neutron activation analysis with high-resolution gamma-ray spectrometry of long-lived radionuclides was developed and used for measurement of trace element contents in samples of bone to determine health and diseases. Using this method, the silver(Ag), cobalt(Co), chromium(Cr), iron(Fe), mercury(Hg), rubidium(Rb), antimony(Sb), selenium(Se), and zinc(Zn) mass fractions were estimated in bone samples from 27 patients with intact bone(12 females and 15 males, aged from 16 to 49 years) who had died from various non-bone-related causes, mainly unexpected traumas,and from 5 patients with chondroma(2 females and 3males, 15–42 years old), obtained from open biopsies or after operation. The reliability of the differences in the results between intact bone and bone affected by chondroma was evaluated by a parametric Student's t test and a nonparametric Mann–Whitney U test. It was found that in the bone affected by chondroma, the mean mass fractions of Co, Cr, Fe, Se, Sb, and Zn were significantly higher than in normal bone tissues. In the neoplastic bone, many correlations between trace elements found in the control group were no longer evident. This work revealed that there is asignificant disturbance of the trace element metabolism in bone affected by chondroma.
文摘A facility and method for109 Cd radionuclide-induced energy-dispersive X-ray fluorescent(EDXRF) were developed to determine the Fe,Zn,Br,Rb,and Sr concentrations in the specimens of human prostatic fluid.Specimens of expressed prostatic fluid were obtained from 51 men(mean age 51 years,range 18–82 years) with apparently normal prostates using standard rectal massage procedure.Mean values(M ± SEL) for concentration of trace elements(mg L^(-1)) in human prostate fluid were:Fe 9.04 ±1.21,Zn 573 ± 35,Br 3.58 ± 0.59,Rb 1.10 ± 0.08,and Sr B 0.76.It was shown that the results of trace element analysis in the micro-samples(20 l L) are sufficiently representative for assessment of the Fe,Zn,Br,and Rb concentration in the prostate fluid.The facility for109 Cd radionuclide-induced EDXRF is comparatively compact and can be located in close proximity to the site of carrying out the massage procedure.The means of Zn and Rb concentration obtained for prostate fluid agree well with median of reported means.For the first time,the Fe and Br concentrations,as well as the upper limit of the Sr concentration,were determined in the human prostate fluid.
文摘The relationship between human and landscape architecture was explored by studying a poem of Bian Zhilin. From the perspectives of social value of landscape architecture, relationship between human and landscape architecture and integrality of landscape architecture, it was proposed that human was also a component of landscape architecture, and participation of human realized the social value of landscape architecture, moreover, human was a kind of landscape while landscape architecture was regarded as a "drama", thus only landscape architecture used by human was a complete one.
基金supported by the State Key Development Program for Basic Research of China (Grant No. 2011CBA00106)the National Natural Science Foundation of China (Grant Nos. 10674006, 81171421, and 61101046)the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238)
文摘A cardiac vector model is presented and verified, and then the forward problem for cardiac magnetic fields and electric potential are discussed based on this model and the realistic human torso volume conductor model, including lungs. A torso-cardiac vector model is used for a 12-lead electrocardiographic (ECG) and magneto-cardiogram (MCG) simulation study by using the boundary element method (BEM). Also, we obtain the MCG wave picture using a compound four-channel HTc.SQUID system in a magnetically shielded room. By comparing the simulated results and experimental results, we verify the cardiac vector model and then do a preliminary study of the forward problem of MCG and ECG. Therefore, the results show that the vector model is reasonable in cardiac electrophysiology.
文摘From the perspective of humanized design concepts, humanized space design and behavioral psychological needs of users were re-interpreted and analyzed, basic elements and design principles of cultural plaza spatial layout were proposed. Particularly, application and role of humanized design in the spatial layout of cultural plaza was analyzed, on the basis of which humanized design objective and orientation for the sustainable development of cultural plaza was defined.
基金The Project Supported by National Natural Science Foundation of China
文摘The preparation of the human hair reference material and the steps taken to confirm its homogeneity and stability as well as its certificatipn are described. Certified values for 17 elements, which are of importance for human health, and reference values for the other 13 elements are provided for this material.