Optimal Selection Model of Equipment Design Scheme Based on Set Pair Analysis

Selecting the optimal one from similar schemes is a paramount work in equipment design.In consideration of similarity of schemes and repetition of characteristic indices,the theory of set pair analysis(SPA)is proposed,and then an optimal selection model is established.In order to improve the accuracy and flexibility,the model is modified by the contribution degree.At last,this model has been validated by an example,and the result demonstrates the method is feasible and valuable for practical usage.

Cumulative logit model in the analysis of endometrial cancer under a matched pair case-control design

Background: Binary as well as polytomous logistic models are widely used for estimating odds ratios when the exposure of prime interest assumes unordered multiple levels under matched pairs case-control design. In our previous studies, we have shown that the use of a polytomous logistic model for estimating cumulative odds ratios when the outcome (response) variable is ordinal (in addition to being polytomous) under matched pairs case-control design. The cumulative odds ratios were estimated based on separate fitting of the model at each of the cutpoint level as compared to less than equal to that level. In this paper we propose an alternative method of estimating the cumulative odds ratios and reanalyze the Los Angeles Endometrial Cancer data in the context of dose levels of conjugated oestrogen exposure and development of endometrial cancer under the matched pair case-control design. Methods: In the present study, the cumulative logit model is fitted using a single multinomial logit model for the data. For this, the full maximum likelihood estimation procedure is adopted. A test for equality of the cumulative odds ratios across the exposure levels is proposed. Results: The analysis revealed that there is a strong evidence of risk for developing endometrial cancer due to oestrogen exposure above each of the three dose level as compared to less than equal to that level. The estimated values at the three cutpoint levels were found to be 6.17, 3.60 and 5.16 respectively. Conclusions: The odds of developing endometrial cancer are very high for the users of any amount of oestrogen, even if it is the least dose, as compared to the non-users.

Impairment of Continuous Insulin Delivery Therapy and Analysis from Graeco-Latin Square Design Model

The desire to deliver measured amount of insulin continuously to patients with type I diabetes, for glycemic control, has attracted a lot of attention. Continuous subcutaneous insulin infusion has seen some success in recent years. However, occlusion of insulin delivery may prevent the patient from receiving the prescribed dosage, with adverse consequence. An in vitro study of insulin delivery is performed, using different insulin pumps, insulin analogs and operating conditions. The aim is to identify incidences of occlusion due to bubble formation in the infusion line. A detailed statistical analysis was performed on the data collected to determine any significant differences and deviations in insulin delivery rates that might be due to factors such as: pump type, the set basal flow rate, insulin type, vibration, and possible insulin occlusion due to air bubble formation within the infusion line. Our findings from the Graeco-Latin Square design model show that there are statistical differences due to the devices, and statistical identifiable clusters are used to distinguish the devices. Such hierarchical models used to describe the analyses, include the flow rate, the pump types, and the activity level.

Stability Analysis of q-axis Rotor Flux Based Model Reference Adaptive System Updating Rotor Time Constant in Induction Motor Drives

q-axis rotor flux can be chosen to form a model reference adaptive system(MRAS)updating rotor time constant online in induction motor drives.This paper presents a stability analysis of such a system with Popov’s hyperstability concept and small-signal linearization technique.At first,the stability of q-axis rotor flux based MRAS is proven with Popov’s Hyperstability theory.Then,to find out the guidelines for optimally designing the coefficients in the PI controller,acting as the adaption mechanism in the MRAS,small-signal model of the estimation system is developed.The obtained linearization model not only allows the stability to be verified further through Routh criterion,but also reveals the distribution of the characteristic roots,which leads to the clue to optimal PI gains.The theoretical analysis and the resultant design guidelines of the adaptation PI gains are verified through simulation and experiments.

AADL2TASM: a Verification and Analysis Tool for AADL Models

Architecture analysis and design language （AADL） is an architecture description language standard for embedded real-time systems and it is widely used in safety-critical applications. For facilitating verifcafion and analysis, model transformation is one of the methods. A synchronous subset of AADL and a general methodology for translating the AADL subset into timed abstract state machine （TASM） were studied. Based on the arias transformation language （ ATL ） framework, the associated translating tool AADL2TASM was implemented by defining the meta-model of both AADL and TASM, and the ATL transformation rules. A case study with property verification of the AADL model was also presented for validating the tool.

Towards a hybrid model-driven platform based on flux balance analysis and a machine learning pipeline for biosystem design

Metabolic modeling and machine learning(ML)are crucial components of the evolving next-generation tools in systems and synthetic biology,aiming to unravel the intricate relationship between genotype,phenotype,and the environment.Nonetheless,the comprehensive exploration of integrating these two frameworks,and fully harnessing the potential of fluxomic data,remains an unexplored territory.In this study,we present,rigorously evaluate,and compare ML-based techniques for data integration.The hybrid model revealed that the overexpression of six target genes and the knockout of seven target genes contribute to enhanced ethanol production.Specifically,we investigated the influence of succinate dehydrogenase(SDH)on ethanol biosynthesis in Saccharomyces cerevisiae through shake flask experiments.The findings indicate a noticeable increase in ethanol yield,ranging from 6%to 10%,in SDH subunit gene knockout strains compared to the wild-type strain.Moreover,in pursuit of a high-yielding strain for ethanol production,dual-gene deletion experiments were conducted targeting glycerol-3-phosphate dehydrogenase(GPD)and SDH.The results unequivocally demonstrate significant enhancements in ethanol production for the engineered strains Δsdh4Δgpd1,Δsdh5Δgpd1,Δsdh6Δgpd1,Δsdh4Δgpd2,Δsdh5Δgpd2,and Δsdh6Δgpd2,with improvements of 21.6%,27.9%,and 22.7%,respectively.Overall,the results highlighted that integrating mechanistic flux features substantially improves the prediction of gene knockout strains not accounted for in metabolic reconstructions.In addition,the finding in this study delivers valuable tools for comprehending and manipulating intricate phenotypes,thereby enhancing prediction accuracy and facilitating deeper insights into mechanistic aspects within the field of synthetic biology.

Photogrammetry, CAD Modeling and FE Analysis for Improving the Performance of a Spinnaker

Objectives： The sails fabrication knew a significant development under the impulse of sailing races like the America＇s Cup and the Volvo around the World Race. These competitions require advanced technologies to increase performance of the sails. In the paper, Reverse Engineering （RE） acquisition, CAD （Computer Aided Design） reconstruction and FE （Finite Element） analysis are used in the design phase for a spinnaker in order to maximize the performance of the sail boat. Materials and Methods： The comparison, between the design data and the characteristics in the real conditions of use of the sail （constant wind pressure acting on the sail）, was carried out by the reconstruction of the three-dimensional CAD model of the spinnaker shape in full-scale, using a non contact Reverse Engineering technique, the photogrammetry and by a FE non linear static analysis. Results： The results of this study show a good correspondence between the design data and the characteristics in the real conditions of use of the sail. Significance： The described methodology is useful for sail makers. It can be successfully adopted to generate three-dimensional CAD-FE models of a sail starting from a very cheap and fast Reverse Engineering non-contact procedure.

Evaluation of the fishbone model in simulating the seismic response of multistory reinforced concrete moment-resisting frames

The fishbone model is a simplified numerical model for moment-resisting frames that is capable of modelling the effects of column-beam strength and stiffness ratios. The applicability of the fishbone model in simulating the seismic responses of reinforced concrete moment-resisting frames of different sets of column-beam strength and stiffness ratios are evaluated through nonlinear static, dynamic and incremental dynamic analysis on six prototype buildings of 4-, 8-and 12-stories. The results show that the fishbone model is practically accurate enough for reinforced concrete frames, although the assumption of equal joint rotation does not hold in all cases. In addition to the ground motion characteristics and the number of stories in the structures, the accuracy of the model also varies with the column-beam stiffness and strength ratios. The model performs better for strong column-weak beam frames, in which the lateral drift patterns are better controlled by the continuous stiffness provided by the strong columns. When the inelastic deformation is large, the accuracy of the model may be subjected to large record-to-record variability. This is especially the case for frames of weak columns.

Comprehensive evaluation of high-steep slope stability and optimal high-steep slope design by 3D physical modeling

High-steep slope stability and its optimal excavation design in Shuichang open pit iron mine were analyzed based on a large 3D physical simulation technique. An optimal excavation scheme with a relatively steeper slope angle was successfully implemented at the northwest wall between Nos. 4 and 5 exploration lines of Shuichang Iron Mine, taking into account the 3D scale effect. The phys-ico-mechanical properties of rock materials were obtained by laboratory tests conducted on sample cores from exploration drilling directly from the iron mine. A porous rock-like composite material was formed for the model, and the mechanical parameters of the material were assessed experimentally;specifically, the effect of water on the sample was quantitatively determined. We adopted an experimental setup using stiff modular applied static loading to carry out a visual excavation of the slope at a random depth. The setup was equipped with acous-tic emission （AE） sensors, and the experiments were monitored by crack optical acquirement, ground penetrating radar, and close-field pho-togrammetry to investigate the mechanisms of rock-mass destabilization in the high-steep slope. For the complex study area, the model re-sults indicated a clear correlation between the model＇s destabilization resulting from slope excavation and the collected monitoring informa-tion. During the model simulation, the overall angle of the slope increased by 1-6 degrees in different sections. Dramatically, the modeled excavation scheme saved over 80 million tons of rock from extraction, generating enormous economic and ecological benefits.

Mechatronic Design and Maneuverability Analysis of a Novel Robotic Shark

In this paper,the mechatronic design and maneuverability analysis of a novel robotic shark are presented.To obtain good maneuverability,a barycenter regulating device is designed to assist the posture adjustment at low speeds.Based on the Newton-Euler approach,an analytical dynamic model is established with particular consideration of pectoral fins for threedimensional motions.The hydrodynamic coefficients are computed using computational fluid dynamics(CFD)methods.Oscillation amplitudes and phases are determined by fitting an optimized fish body wave.The performance of the robotic shark is estimated by varying the oscillation frequency and offset angle.The results show that with oscillation frequency increasing,the swimming speed increases linearly.The robotic shark reaches the maximum swimming speed of 1.05 m/s with an oscillation frequency of 1.2 Hz.Furthermore,the turning radius decreases nonlinearly as the offset angle increased.The robotic shark reaches the minimum turning radius of 1.4 times the body length with 0.2 Hz frequency and 12°offset angle.In the vertical plane,as the pectoral fin angle increases,the diving velocity increases nonlinearly with increase rate slowing down.

The Computer Aided Integrated Design and Analysis of Oil Tank in Vehicle

This paper creates 3D solid model and assembly of U RJ 92-6 oil tank and analyses its strength by integrated CAD/CAE/CAM software I-D EAS. Through integrated simulation in computer, design efficiency and quality of oil tank is greatly improved. Adopting integrated CAD/CAE/CAM software to carry out integrated research to equ ipment and products, we will be able to take overall analysis in aspects of 3-D solid modeling, pre-assembly and strength, etc., to realize non-paper designi ng and parallel designing. Problems can be found and settled during designing, w hich will increase designing efficiency and one-time success rate and realize o ptimum designing for products.

Application of time series modeling to a national reference frame realization

This paper presents an option for modern dynamic terrestrial reference system realization in Uzbekistan for user needs. An additive model is explored to predict patterns of time series and investigate means of constructing forecast time series models in the future. The main components(trend, periodical, and irregular) of the KIUB(DORIS) and KIT3, TASH, MADK, and MTAL(GNSS) international stations coordinate time series were investigated. It was shown that seasonal nonlinear trends occurred both in the height(U) component of all stations and the east(E) component of high mountainous stations such as MTAL and MADK. The seasonal periodical portion of the time series determined from the additive model has a complicated pattern for all sites and can be explained as both hydrological signals in the region and improvement of observational quality. Amplitudes of the best-fitting sinusoids in the North component ranged between 1.73 and 8.76 mm; the East component ranged between 0.82 and 11.92 mm; and the Up component ranged between 3.11 and 40.81 mm. Regression analysis of the irregular portion of the height component of the two techniques at the Kitab station using tropospheric parameters(pressure and temperature) was confirmed as only 57% of the stochastic portion of the time series.

3-D MODELLING OF COMPUTER AIDED GARMENT DESIGN

This paper describes a method of the computer aided garment design,and discusses 3-D humanbody,wire frame modelling,approaches of expressing and a shading model of the 3-D garment.

Progressive Collapse Analysis of Concrete-Filled Steel Tubular Frames with Semi-rigid Connections

A 9-story concrete-filled steel tubular frame model is used to analyze the response of joints due to sudden column loss. Three different models are developed and compared to study the efficiency and feasibility of simulation, which include substructure model, beam element model and solid element model. The comparison results show that the substructure model has a satisfying capability, calculation efficiency and accuracy to predict the concerned joints as well as the overall framework. Based on the substructure model and a kind of semi-rigid connection for concretefilled square hollow section steel column proposed in this paper, the nonlinear dynamic analyses are conducted by the alternate path method. It is found that the removal of the ground inner column brings high-level joint moments and comparatively low-level axial tension forces. The initial stiffness and transmitted ultimate moment of the semi-rigid connection are the main factors that influence the frame behavior, and their lower limit should be guaranteed to resist collapse. Reduced ultimate moment results in drastic displacement and axial force development, which may bring progressive collapse. The higher initial stiffness ensures that the structure has a stronger capacity to resist progressive collapse.

Ecotect Analysis太阳辐射分析在园林植物场景中的应用

Ecotect Analysis在园林场景分析中应用的时间较短,在园林领域中仅仅用于居住区等建筑物较多的区域分析,在以往的园林植物景观场景分析中也没有进行过深入的探讨和研究。文章对Ecotect Analysis在植物景观场景分析方面的方法、手段加以推敲和整理,使Ecotect Analysis在园林植物景观场景中的太阳辐射分析得以应用。

一种在紧框架下求解Analysis Dantzig-selector模型的快速算法

Analysis Dantzig-selector模型是基于经典Dantzig-selector的l_(∞)限制的l_(1)分析模型。本文使用了紧框架下求解此模型的线性化交替方向乘子法,使得每个子问题都有显式解析解,并通过数值实验证明了该方法的有效可行性。

DYNAMIC FINITE ELEMENT MODEL UPDATING BASED ON GLOBAL INFORMATION OF STRUCTURES

Finite element model updating method based on global information is proposed.Prior investigation upon design space of structural parameters is performed before updating usingstatistic analysis, including parameter screening using variance analysis and response surfacefitting using regression analysis. The parameter screening method selects the design parametersconsidering the result of hypothesis testing, which is a kind of global information. Meanwhile, thetraditional updating method considers local sensitivity which only gives the information at solepoint in the design space. Response surface fitting constructs a close-form multinomial whichdescribes the relationship between concerned structural feature and selected updating parameters. Itis an approximation to finite element models(FEM) and used as a substitution in the updatingiterations. The presented updating method can be applied without the restriction of linearassumption. In addition, there is no data exchange between the updating program and the finite-element analysis program in the updating iterations. This makes the method practical inengineering. An aircraft test structure, GARTEUR, is employed to verify the effectiveness of themethod. After updating, the error of modal frequencies is less than 3 percent.

Uncertainty analysis of seawater intrusion forecasting

In order to describe the importance of uncertainty analysis in seawater intrusion forecasting and identify the main factors that might cause great differences in prediction results, we analyzed the influence of sea level rise, tidal effect, the seasonal variance of influx, and the annual variance of the pumping rate, as well as combinations of different parameters. The results show that the most important factors that might cause great differences in seawater intrusion distance are the variance of pumping rate and combinations of different parameters. The influence of sea level rise can be neglected in a short-time simulation （ten years, for instance）. Retardation of seawater intrusion caused by tidal effects is obviously important in aquifers near the coastline, but the influence decreases with distance away from the coastline and depth away from the seabed. The intrusion distance can reach a dynamic equilibrium with the application of the sine function for seasonal effects of influx. As a conclusion, we suggest that uncertainty analysis should be considered in seawater intrusion forecasting, if possible.

DCEFM Model for Emergency Risk Assessment of Ship Inflow

This paper proposes a risk assessment model considering danger zone,capsizing time,and evaluation time factors(DCEFM)to quantify the emergency risk of ship inflow and calculate the degree of different factors to the emergency risk of water inflow.The DCEFM model divides the water inflow risk factors into danger zone,capsizing time,and evacuation time factors.The danger zone,capsizing time,and evacuation factors are calculated on the basis of damage stability probability,the numerical simulation of water inflow,and personnel evacuation simulation,respectively.The risk of a capsizing scenario is quantified by risk loss.The functional relationship between the location of the danger zone and the probability of damage,the information of breach and the water inflow time,the inclination angle and the evacuation time,and the contribution of different factors to the risk model of ship water inflow are obtained.Results of the DCEFM show that the longitudinal position of the damaged zone and the area of the breach have the greatest impact on the risk.A simple local watertight plate adjustment in the high-risk area can improve the safety of the ship.