In translation, hybridity often poses a big challenge to the translator, especially when the hybrid text is a novel. The au-thor of this paper hopes to contribute to the study of the translation of hybridity in Englis...In translation, hybridity often poses a big challenge to the translator, especially when the hybrid text is a novel. The au-thor of this paper hopes to contribute to the study of the translation of hybridity in English novels by drawing on Bakhtin's theory ofdialogue. By analyzing the translation of linguistic hybridity in Saving Fish from Drowning, the author of this paper finds that thetranslation by Caiju is not good enough and tries to provide a new direction by virtue of which translators can choose right transla-tion strategies.展开更多
John Maxwell Coetzee's masterpiece-Disgrace is the representative work about post colonialism. The novel describes a series of disgraceful events happened between the white and the black in the post apartheid Sout...John Maxwell Coetzee's masterpiece-Disgrace is the representative work about post colonialism. The novel describes a series of disgraceful events happened between the white and the black in the post apartheid South Africa. The famous literature theory- hybridity of Homi K. Bhabha is the very key theory to analyze the work. In post apartheid South Africa, hybridity is the only way for the white and the black to coexist.展开更多
For Chinese poetry to be effectively translated into English,one should take many factors into account,such as the translation of images,the conveyance of the general mood,and cultural transmission.Therefore,poetry tr...For Chinese poetry to be effectively translated into English,one should take many factors into account,such as the translation of images,the conveyance of the general mood,and cultural transmission.Therefore,poetry translation has long been regarded as a significant part of literature translation,which arouses much discussion on translation strategies and methodologies.As a representative of post-colonial theorists,Homi K.Bhabha proposes the notion of"Hybridity",which sheds lights on the strategies and processes of translation.From the perspective of Hybridity,this paper makes a tentative analysis of two English versions of the Chinese Qu poem Tian-Jing-Sha-Qiusi,emphasizing the hybrid of different cultures as an important approach to poetry translation.展开更多
Holo Taiwan Residents Opera Troupe has produced a series of intercultural performances in Taiwan Residents Opera since the troupe adapted Nikolai Vasilievich Gogol＇s （1809-1852） The Government Inspector in 1996. In...Holo Taiwan Residents Opera Troupe has produced a series of intercultural performances in Taiwan Residents Opera since the troupe adapted Nikolai Vasilievich Gogol＇s （1809-1852） The Government Inspector in 1996. In fact, there is a huge controversy over these intercultural performances which fuse western drama with traditional Taiwan Residents performing art because such a kind of theatrical hybridity lacks the spirit of the original and damages the aesthetics of native performing art practice. In 2002, Holo adapted William Shakespeare＇s Hamlet into a six-hour-long performance, Tai Tzu Fu Chou （The Prince＇s Vengeful Plan）, which the troupe tried to explore new source for traditional Taiwan Residents Opera and expected to bring something new to Taiwan Residents audience. However, The Prince＇s Vengeful Plan is considered ＂cultural collage＂ as well as an unsuccessful intercultural performance. Besides, The Prince＇s Vengeful Plan is accused to blaspheme Shakespeare because the performance merely maintains the frame of the original and distorts the spirit of the original. According to Rustom Bharucha, the most problematic aspect of intercultural performance is ＂de-historicizing tendency＂, and such a condition explains why Holo＇s The Prince＇s Vengeful Plan cannot transcend the original. In order to detect the problems of intercultural adaptation in Holo＇s The Prince Vengeful Plan, we cover the related issues in three aspects： （1） to discuss the development of Taiwan Residents Opera in Taiwan; （2） to explore the cultural conflicts when the text of the source culture is adapted into the performance of the target culture; and （3） to see how and why the spirit and aesthetics of Shakespeare＇s verses in Hamlet are distorted in Holo＇s theatrical adaptation. After that, we expect to conclude the impossibility of adapting Shakespeare＇s play into traditional Taiwan Residents Opera in the case of Holo＇s The Prince＇s Vengeful Plan.展开更多
In recent years,abundant words with Chinese characteristics in media translation show that on the one hand,the unique society,politics,economics and culture,and on the other hand,the important source of foreign words....In recent years,abundant words with Chinese characteristics in media translation show that on the one hand,the unique society,politics,economics and culture,and on the other hand,the important source of foreign words.According to post colonial cultural translation theory,through different hybridization tactics,they formed the third part,which is different from the source language and target language,and is the product of globalization.This notion of hybridity not only has great bearing on translators’selection of translating strategies,but also helps to change some of the accepted conception about translation,and thus enables us to have a better understanding of media translation.This promotes China’s discourse power in international society and the objectivity of reports of China,which constructs the third space in media translation between the West and China.展开更多
This paper examines the formation of the self in the context of emigration and the Indian individual in the Anglo-American space, in the novels: Fasting, Feasting by Anita Desai, The Inheritance of Loss by Kiran Desai...This paper examines the formation of the self in the context of emigration and the Indian individual in the Anglo-American space, in the novels: Fasting, Feasting by Anita Desai, The Inheritance of Loss by Kiran Desai, and The Namesake by Jhumpa Lahiri. The analysis focuses on exploring the way in which the hyphenated self is constructed under the influences of dialogical negotiation of desh and pardesh in the context of racism, global-local (glocal) specificity, becoming authenic under the presure of home memory, diaspora ethnicity and mimicry. Is reterritorialization and acculturation successful for the hybrid self? The answers is to be found by the characters of the novels and shown in instances of self expression and integration. Arun, the Indian guy, from Anita Desai’s novel left India for studying in America. During the summer, he is accommodated to an American family. The clash between the two cultures, traditions, and customs is felt as a huge breakage, which leads to desintegration and alienation. Biju and Harish-Harry from Kiran Desai’s novel go to America for a better living, and they succeeed in finding a job at a bakery. The impact of racism is higher in the lower strata of the society, thus their chances to integration are lost;Biju decides to return home, while Harish-Harry ends in a hyphenated self and a dissatisfied living. In The Namesake, Ashoke and Ashima, the Indian emigrants husband and wife, experience a different reshaping of identity. Ashoke works as a university assistant, while Ashima is a housewife. For him, America is a space for affirmation and self-verification, while for his wife, the space becomes a ghetto where she feels lonely and marginalised. Therefore, in the formation of the self there are many coordinates which should be taken into consideration and above this, their impact over the immigrant is different from case to case depending on many factors.展开更多
An embedded system is a system that computer is used as a componelit ina larger device. In this paper, we study hybridity in embedded systems andpresent an interval based temporal logic to express and reason about hyb...An embedded system is a system that computer is used as a componelit ina larger device. In this paper, we study hybridity in embedded systems andpresent an interval based temporal logic to express and reason about hybridproperties of such ldnd of systems.展开更多
BACKGROUND Acute myeloid leukemia(AML)is a complicated disease with uncontrolled hematopoietic precursor proliferation induced by various genetic alterations.Runt-related transcription factor-1(RUNX1)is commonly disru...BACKGROUND Acute myeloid leukemia(AML)is a complicated disease with uncontrolled hematopoietic precursor proliferation induced by various genetic alterations.Runt-related transcription factor-1(RUNX1)is commonly disrupted by chromosomal translocations in hematological malignancies.AIM To characterize RUNX1 gene rearrangements and copy number variations in newly diagnosed adult AML patients,with an emphasis on the impact of clinical and laboratory features on the outcome.METHODS Fluorescence in situ hybridization was used to test RUNX1 gene alterations in 77 newly diagnosed adult AML cases.NPM1,FLT3/ITD,FLT3/TKD,and KIT mutations were tested by PCR.Prognostic clinical and laboratory findings were studied in relation to RUNX1 alterations.RESULTS RUNX1 abnormalities were detected by fluorescence in situ hybridization in 41.6%of patients:20.8%had translocations,22.1%had amplification,and 5.2%had deletion.Translocations prevailed in AML-M2(P=0.019)with a positive expression of myeloperoxidase(P=0.031),whereas deletions dominated in M4 and M5 subtypes(P=0.008)with a positive association with CD64 expression(P=0.05).The modal chromosomal number was higher in cases having amplifications(P=0.007)and lower in those with deletions(P=0.008).RUNX1 abnormalities were associated with complex karyotypes(P<0.001)and were mutually exclusive of NPM1 mutations.After 44 months of follow-up,RUNX1 abnormalities affected neither patients’response to treatment nor overall survival.CONCLUSION RUNX1 abnormalities were mutually exclusive of NPM1 mutations.RUNX1 abnormalities affected neither patients’response to treatment nor overall survival.展开更多
Safe and efficient sortie scheduling on the confined flight deck is crucial for maintaining high combat effectiveness of the aircraft carrier.The primary difficulty exactly lies in the spatiotemporal coordination,i.e....Safe and efficient sortie scheduling on the confined flight deck is crucial for maintaining high combat effectiveness of the aircraft carrier.The primary difficulty exactly lies in the spatiotemporal coordination,i.e.,allocation of limited supporting resources and collision-avoidance between heterogeneous dispatch entities.In this paper,the problem is investigated in the perspective of hybrid flow-shop scheduling problem by synthesizing the precedence,space and resource constraints.Specifically,eight processing procedures are abstracted,where tractors,preparing spots,catapults,and launching are virtualized as machines.By analyzing the constraints in sortie scheduling,a mixed-integer planning model is constructed.In particular,the constraint on preparing spot occupancy is improved to further enhance the sortie efficiency.The basic trajectory library for each dispatch entity is generated and a delayed strategy is integrated to address the collision-avoidance issue.To efficiently solve the formulated HFSP,which is essentially a combinatorial problem with tightly coupled constraints,a chaos-initialized genetic algorithm is developed.The solution framework is validated by the simulation environment referring to the Fort-class carrier,exhibiting higher sortie efficiency when compared to existing strategies.And animation of the simulation results is available at www.bilibili.com/video/BV14t421A7Tt/.The study presents a promising supporting technique for autonomous flight deck operation in the foreseeable future,and can be easily extended to other supporting scenarios,e.g.,ammunition delivery and aircraft maintenance.展开更多
In this paper,we propose a sub-6GHz channel assisted hybrid beamforming(HBF)for mmWave system under both line-of-sight(LOS)and non-line-of-sight(NLOS)scenarios without mmWave channel estimation.Meanwhile,we resort to ...In this paper,we propose a sub-6GHz channel assisted hybrid beamforming(HBF)for mmWave system under both line-of-sight(LOS)and non-line-of-sight(NLOS)scenarios without mmWave channel estimation.Meanwhile,we resort to the selfsupervised approach to eliminate the need for labels,thus avoiding the accompanied high cost of data collection and annotation.We first construct the dense connection network(DCnet)with three modules:the feature extraction module for extracting channel characteristic from a large amount of channel data,the feature fusion module for combining multidimensional features,and the prediction module for generating the HBF matrices.Next,we establish a lightweight network architecture,named as LDnet,to reduce the number of model parameters and computational complexity.The proposed sub-6GHz assisted approach eliminates mmWave pilot resources compared to the method using mmWave channel information directly.The simulation results indicate that the proposed DCnet and LDnet can achieve the spectral efficiency that is superior to the traditional orthogonal matching pursuit(OMP)algorithm by 13.66% and 10.44% under LOS scenarios and by 32.35% and 27.75% under NLOS scenarios,respectively.Moreover,the LDnet achieves 98.52% reduction in the number of model parameters and 22.93% reduction in computational complexity compared to DCnet.展开更多
The amount of oxygen blown into the converter is one of the key parameters for the control of the converter blowing process,which directly affects the tap-to-tap time of converter. In this study, a hybrid model based ...The amount of oxygen blown into the converter is one of the key parameters for the control of the converter blowing process,which directly affects the tap-to-tap time of converter. In this study, a hybrid model based on oxygen balance mechanism (OBM) and deep neural network (DNN) was established for predicting oxygen blowing time in converter. A three-step method was utilized in the hybrid model. First, the oxygen consumption volume was predicted by the OBM model and DNN model, respectively. Second, a more accurate oxygen consumption volume was obtained by integrating the OBM model and DNN model. Finally, the converter oxygen blowing time was calculated according to the oxygen consumption volume and the oxygen supply intensity of each heat. The proposed hybrid model was verified using the actual data collected from an integrated steel plant in China, and compared with multiple linear regression model, OBM model, and neural network model including extreme learning machine, back propagation neural network, and DNN. The test results indicate that the hybrid model with a network structure of 3 hidden layer layers, 32-16-8 neurons per hidden layer, and 0.1 learning rate has the best prediction accuracy and stronger generalization ability compared with other models. The predicted hit ratio of oxygen consumption volume within the error±300 m^(3)is 96.67%;determination coefficient (R^(2)) and root mean square error (RMSE) are0.6984 and 150.03 m^(3), respectively. The oxygen blow time prediction hit ratio within the error±0.6 min is 89.50%;R2and RMSE are0.9486 and 0.3592 min, respectively. As a result, the proposed model can effectively predict the oxygen consumption volume and oxygen blowing time in the converter.展开更多
With the diversified development of big data,detection and precision guidance technologies,electromagnetic(EM)functional materials and devices serving multiple spectrums have become a hot topic.Exploring the multispec...With the diversified development of big data,detection and precision guidance technologies,electromagnetic(EM)functional materials and devices serving multiple spectrums have become a hot topic.Exploring the multispectral response of materials is a challenging and meaningful scientific question.In this study,MXene/TiO_(2)hybrids with tunable conduction loss and polarization relaxation are fabricated by in situ atomic reconstruction engineering.More importantly,MXene/TiO_(2)hybrids exhibit adjustable spectral responses in the GHz,infrared and visible spectrums,and several EM devices are constructed based on this.An antenna array provides excellent EM energy harvesting in multiple microwave bands,with|S11|up to−63.2 dB,and can be tuned by the degree of bending.An ultra-wideband bandpass filter realizes a passband of about 5.4 GHz and effectively suppresses the transmission of EM signals in the stopband.An infrared stealth device has an emissivity of less than 0.2 in the infrared spectrum at wavelengths of 6-14μm.This work can provide new inspiration for the design and development of multifunctional,multi-spectrum EM devices.展开更多
Metal-organic frameworks(MOFs)have been developed as an ideal platform for exploration of the relationship between intrinsic structure and catalytic activity,but the limited catalytic activity and stability has hamper...Metal-organic frameworks(MOFs)have been developed as an ideal platform for exploration of the relationship between intrinsic structure and catalytic activity,but the limited catalytic activity and stability has hampered their practical use in water splitting.Herein,we develop a bond length adjustment strategy for optimizing naphthalene-based MOFs that synthesized by acid etching Co-naphthalenedicarboxylic acid-based MOFs(donated as AE-CoNDA)to serve as efficient catalyst for water splitting.AE-CoNDA exhibits a low overpotential of 260 mV to reach 10 mA cm^(−2)and a small Tafel slope of 62 mV dec^(−1)with excellent stability over 100 h.After integrated AE-CoNDA onto BiVO_(4),photocurrent density of 4.3 mA cm^(−2)is achieved at 1.23 V.Experimental investigations demonstrate that the stretched Co-O bond length was found to optimize the orbitals hybridization of Co 3d and O 2p,which accounts for the fast kinetics and high activity.Theoretical calculations reveal that the stretched Co-O bond length strengthens the adsorption of oxygen-contained intermediates at the Co active sites for highly efficient water splitting.展开更多
Vertically oriented carbon structures constructed from low-dimen-sional carbon materials are ideal frameworks for high-performance thermal inter-face materials(TIMs).However,improving the interfacial heat-transfer eff...Vertically oriented carbon structures constructed from low-dimen-sional carbon materials are ideal frameworks for high-performance thermal inter-face materials(TIMs).However,improving the interfacial heat-transfer efficiency of vertically oriented carbon structures is a challenging task.Herein,an orthotropic three-dimensional(3D)hybrid carbon network(VSCG)is fabricated by depositing vertically aligned carbon nanotubes(VACNTs)on the surface of a horizontally oriented graphene film(HOGF).The interfacial interaction between the VACNTs and HOGF is then optimized through an annealing strategy.After regulating the orientation structure of the VACNTs and filling the VSCG with polydimethylsi-loxane(PDMS),VSCG/PDMS composites with excellent 3D thermal conductive properties are obtained.The highest in-plane and through-plane thermal conduc-tivities of the composites are 113.61 and 24.37 W m^(-1)K^(-1),respectively.The high contact area of HOGF and good compressibility of VACNTs imbue the VSCG/PDMS composite with low thermal resistance.In addition,the interfacial heat-transfer efficiency of VSCG/PDMS composite in the TIM performance was improved by 71.3%compared to that of a state-of-the-art thermal pad.This new structural design can potentially realize high-performance TIMs that meet the need for high thermal conductivity and low contact thermal resistance in interfacial heat-transfer processes.展开更多
Gamma-aminobutyric acid(GABA)ergic neurons,the most abundant inhibitory neurons in the human brain,have been found to be reduced in many neurological disorders,including Alzheimer's disease and Alzheimer's dis...Gamma-aminobutyric acid(GABA)ergic neurons,the most abundant inhibitory neurons in the human brain,have been found to be reduced in many neurological disorders,including Alzheimer's disease and Alzheimer's disease-related dementia.Our previous study identified the upregulation of microRNA-502-3p(miR-502-3p)and downregulation of GABA type A receptor subunitα-1 in Alzheimer's disease synapses.This study investigated a new molecular relationship between miR-502-3p and GABAergic synapse function.In vitro studies were perfo rmed using the mouse hippocampal neuronal cell line HT22 and miR-502-3p agomiRs and antagomiRs.In silico analysis identified multiple binding sites of miR-502-3p at GABA type A receptor subunitα-1 mRNA.Luciferase assay confirmed that miR-502-3p targets the GABA type A receptor subunitα-1 gene and suppresses the luciferase activity.Furthermore,quantitative reve rse transcription-polymerase chain reaction,miRNA in situ hybridization,immunoblotting,and immunostaining analysis confirmed that overexpression of miR-502-3p reduced the GABA type A receptor subunitα-1 level,while suppression of miR-502-3p increased the level of GABA type A receptor subunitα-1 protein.Notably,as a result of the overexpression of miR-502-3p,cell viability was found to be reduced,and the population of necrotic cells was found to be increased.The whole cell patch-clamp analysis of human-GABA receptor A-α1/β3/γ2L human embryonic kidney(HEK)recombinant cell line also showed that overexpression of miR-502-3p reduced the GABA current and overall GABA function,suggesting a negative correlation between miR-502-3p levels and GABAergic synapse function.Additionally,the levels of proteins associated with Alzheimer s disease were high with miR-502-3p overexpression and reduced with miR-502-3p suppression.The present study provides insight into the molecular mechanism of regulation of GABAergic synapses by miR-502-3p.We propose that micro-RNA,in particular miR-502-3p,could be a potential therapeutic to rget to modulate GABAergic synapse function in neurological disorders,including Alzheimer's disease and Alzheimer's diseaserelated dementia.展开更多
Accurate soil moisture(SM)prediction is critical for understanding hydrological processes.Physics-based(PB)models exhibit large uncertainties in SM predictions arising from uncertain parameterizations and insufficient...Accurate soil moisture(SM)prediction is critical for understanding hydrological processes.Physics-based(PB)models exhibit large uncertainties in SM predictions arising from uncertain parameterizations and insufficient representation of land-surface processes.In addition to PB models,deep learning(DL)models have been widely used in SM predictions recently.However,few pure DL models have notably high success rates due to lacking physical information.Thus,we developed hybrid models to effectively integrate the outputs of PB models into DL models to improve SM predictions.To this end,we first developed a hybrid model based on the attention mechanism to take advantage of PB models at each forecast time scale(attention model).We further built an ensemble model that combined the advantages of different hybrid schemes(ensemble model).We utilized SM forecasts from the Global Forecast System to enhance the convolutional long short-term memory(ConvLSTM)model for 1–16 days of SM predictions.The performances of the proposed hybrid models were investigated and compared with two existing hybrid models.The results showed that the attention model could leverage benefits of PB models and achieved the best predictability of drought events among the different hybrid models.Moreover,the ensemble model performed best among all hybrid models at all forecast time scales and different soil conditions.It is highlighted that the ensemble model outperformed the pure DL model over 79.5%of in situ stations for 16-day predictions.These findings suggest that our proposed hybrid models can adequately exploit the benefits of PB model outputs to aid DL models in making SM predictions.展开更多
文摘In translation, hybridity often poses a big challenge to the translator, especially when the hybrid text is a novel. The au-thor of this paper hopes to contribute to the study of the translation of hybridity in English novels by drawing on Bakhtin's theory ofdialogue. By analyzing the translation of linguistic hybridity in Saving Fish from Drowning, the author of this paper finds that thetranslation by Caiju is not good enough and tries to provide a new direction by virtue of which translators can choose right transla-tion strategies.
文摘John Maxwell Coetzee's masterpiece-Disgrace is the representative work about post colonialism. The novel describes a series of disgraceful events happened between the white and the black in the post apartheid South Africa. The famous literature theory- hybridity of Homi K. Bhabha is the very key theory to analyze the work. In post apartheid South Africa, hybridity is the only way for the white and the black to coexist.
文摘For Chinese poetry to be effectively translated into English,one should take many factors into account,such as the translation of images,the conveyance of the general mood,and cultural transmission.Therefore,poetry translation has long been regarded as a significant part of literature translation,which arouses much discussion on translation strategies and methodologies.As a representative of post-colonial theorists,Homi K.Bhabha proposes the notion of"Hybridity",which sheds lights on the strategies and processes of translation.From the perspective of Hybridity,this paper makes a tentative analysis of two English versions of the Chinese Qu poem Tian-Jing-Sha-Qiusi,emphasizing the hybrid of different cultures as an important approach to poetry translation.
文摘Holo Taiwan Residents Opera Troupe has produced a series of intercultural performances in Taiwan Residents Opera since the troupe adapted Nikolai Vasilievich Gogol＇s （1809-1852） The Government Inspector in 1996. In fact, there is a huge controversy over these intercultural performances which fuse western drama with traditional Taiwan Residents performing art because such a kind of theatrical hybridity lacks the spirit of the original and damages the aesthetics of native performing art practice. In 2002, Holo adapted William Shakespeare＇s Hamlet into a six-hour-long performance, Tai Tzu Fu Chou （The Prince＇s Vengeful Plan）, which the troupe tried to explore new source for traditional Taiwan Residents Opera and expected to bring something new to Taiwan Residents audience. However, The Prince＇s Vengeful Plan is considered ＂cultural collage＂ as well as an unsuccessful intercultural performance. Besides, The Prince＇s Vengeful Plan is accused to blaspheme Shakespeare because the performance merely maintains the frame of the original and distorts the spirit of the original. According to Rustom Bharucha, the most problematic aspect of intercultural performance is ＂de-historicizing tendency＂, and such a condition explains why Holo＇s The Prince＇s Vengeful Plan cannot transcend the original. In order to detect the problems of intercultural adaptation in Holo＇s The Prince Vengeful Plan, we cover the related issues in three aspects： （1） to discuss the development of Taiwan Residents Opera in Taiwan; （2） to explore the cultural conflicts when the text of the source culture is adapted into the performance of the target culture; and （3） to see how and why the spirit and aesthetics of Shakespeare＇s verses in Hamlet are distorted in Holo＇s theatrical adaptation. After that, we expect to conclude the impossibility of adapting Shakespeare＇s play into traditional Taiwan Residents Opera in the case of Holo＇s The Prince＇s Vengeful Plan.
文摘In recent years,abundant words with Chinese characteristics in media translation show that on the one hand,the unique society,politics,economics and culture,and on the other hand,the important source of foreign words.According to post colonial cultural translation theory,through different hybridization tactics,they formed the third part,which is different from the source language and target language,and is the product of globalization.This notion of hybridity not only has great bearing on translators’selection of translating strategies,but also helps to change some of the accepted conception about translation,and thus enables us to have a better understanding of media translation.This promotes China’s discourse power in international society and the objectivity of reports of China,which constructs the third space in media translation between the West and China.
文摘This paper examines the formation of the self in the context of emigration and the Indian individual in the Anglo-American space, in the novels: Fasting, Feasting by Anita Desai, The Inheritance of Loss by Kiran Desai, and The Namesake by Jhumpa Lahiri. The analysis focuses on exploring the way in which the hyphenated self is constructed under the influences of dialogical negotiation of desh and pardesh in the context of racism, global-local (glocal) specificity, becoming authenic under the presure of home memory, diaspora ethnicity and mimicry. Is reterritorialization and acculturation successful for the hybrid self? The answers is to be found by the characters of the novels and shown in instances of self expression and integration. Arun, the Indian guy, from Anita Desai’s novel left India for studying in America. During the summer, he is accommodated to an American family. The clash between the two cultures, traditions, and customs is felt as a huge breakage, which leads to desintegration and alienation. Biju and Harish-Harry from Kiran Desai’s novel go to America for a better living, and they succeeed in finding a job at a bakery. The impact of racism is higher in the lower strata of the society, thus their chances to integration are lost;Biju decides to return home, while Harish-Harry ends in a hyphenated self and a dissatisfied living. In The Namesake, Ashoke and Ashima, the Indian emigrants husband and wife, experience a different reshaping of identity. Ashoke works as a university assistant, while Ashima is a housewife. For him, America is a space for affirmation and self-verification, while for his wife, the space becomes a ghetto where she feels lonely and marginalised. Therefore, in the formation of the self there are many coordinates which should be taken into consideration and above this, their impact over the immigrant is different from case to case depending on many factors.
文摘An embedded system is a system that computer is used as a componelit ina larger device. In this paper, we study hybridity in embedded systems andpresent an interval based temporal logic to express and reason about hybridproperties of such ldnd of systems.
文摘BACKGROUND Acute myeloid leukemia(AML)is a complicated disease with uncontrolled hematopoietic precursor proliferation induced by various genetic alterations.Runt-related transcription factor-1(RUNX1)is commonly disrupted by chromosomal translocations in hematological malignancies.AIM To characterize RUNX1 gene rearrangements and copy number variations in newly diagnosed adult AML patients,with an emphasis on the impact of clinical and laboratory features on the outcome.METHODS Fluorescence in situ hybridization was used to test RUNX1 gene alterations in 77 newly diagnosed adult AML cases.NPM1,FLT3/ITD,FLT3/TKD,and KIT mutations were tested by PCR.Prognostic clinical and laboratory findings were studied in relation to RUNX1 alterations.RESULTS RUNX1 abnormalities were detected by fluorescence in situ hybridization in 41.6%of patients:20.8%had translocations,22.1%had amplification,and 5.2%had deletion.Translocations prevailed in AML-M2(P=0.019)with a positive expression of myeloperoxidase(P=0.031),whereas deletions dominated in M4 and M5 subtypes(P=0.008)with a positive association with CD64 expression(P=0.05).The modal chromosomal number was higher in cases having amplifications(P=0.007)and lower in those with deletions(P=0.008).RUNX1 abnormalities were associated with complex karyotypes(P<0.001)and were mutually exclusive of NPM1 mutations.After 44 months of follow-up,RUNX1 abnormalities affected neither patients’response to treatment nor overall survival.CONCLUSION RUNX1 abnormalities were mutually exclusive of NPM1 mutations.RUNX1 abnormalities affected neither patients’response to treatment nor overall survival.
基金the financial support of the National Key Research and Development Plan(2021YFB3302501)the financial support of the National Natural Science Foundation of China(12102077)。
文摘Safe and efficient sortie scheduling on the confined flight deck is crucial for maintaining high combat effectiveness of the aircraft carrier.The primary difficulty exactly lies in the spatiotemporal coordination,i.e.,allocation of limited supporting resources and collision-avoidance between heterogeneous dispatch entities.In this paper,the problem is investigated in the perspective of hybrid flow-shop scheduling problem by synthesizing the precedence,space and resource constraints.Specifically,eight processing procedures are abstracted,where tractors,preparing spots,catapults,and launching are virtualized as machines.By analyzing the constraints in sortie scheduling,a mixed-integer planning model is constructed.In particular,the constraint on preparing spot occupancy is improved to further enhance the sortie efficiency.The basic trajectory library for each dispatch entity is generated and a delayed strategy is integrated to address the collision-avoidance issue.To efficiently solve the formulated HFSP,which is essentially a combinatorial problem with tightly coupled constraints,a chaos-initialized genetic algorithm is developed.The solution framework is validated by the simulation environment referring to the Fort-class carrier,exhibiting higher sortie efficiency when compared to existing strategies.And animation of the simulation results is available at www.bilibili.com/video/BV14t421A7Tt/.The study presents a promising supporting technique for autonomous flight deck operation in the foreseeable future,and can be easily extended to other supporting scenarios,e.g.,ammunition delivery and aircraft maintenance.
基金supported in part by the National Natural Science Foundation of China under Grants 62325107,62341107,62261160650,and U23A20272in part by the Beijing Natural Science Foundation under Grant L222002.
文摘In this paper,we propose a sub-6GHz channel assisted hybrid beamforming(HBF)for mmWave system under both line-of-sight(LOS)and non-line-of-sight(NLOS)scenarios without mmWave channel estimation.Meanwhile,we resort to the selfsupervised approach to eliminate the need for labels,thus avoiding the accompanied high cost of data collection and annotation.We first construct the dense connection network(DCnet)with three modules:the feature extraction module for extracting channel characteristic from a large amount of channel data,the feature fusion module for combining multidimensional features,and the prediction module for generating the HBF matrices.Next,we establish a lightweight network architecture,named as LDnet,to reduce the number of model parameters and computational complexity.The proposed sub-6GHz assisted approach eliminates mmWave pilot resources compared to the method using mmWave channel information directly.The simulation results indicate that the proposed DCnet and LDnet can achieve the spectral efficiency that is superior to the traditional orthogonal matching pursuit(OMP)algorithm by 13.66% and 10.44% under LOS scenarios and by 32.35% and 27.75% under NLOS scenarios,respectively.Moreover,the LDnet achieves 98.52% reduction in the number of model parameters and 22.93% reduction in computational complexity compared to DCnet.
基金financially supported by the National Natural Science Foundation of China (Nos.51974023 and52374321)the funding of State Key Laboratory of Advanced Metallurgy,University of Science and Technology Beijing,China (No.41620007)。
文摘The amount of oxygen blown into the converter is one of the key parameters for the control of the converter blowing process,which directly affects the tap-to-tap time of converter. In this study, a hybrid model based on oxygen balance mechanism (OBM) and deep neural network (DNN) was established for predicting oxygen blowing time in converter. A three-step method was utilized in the hybrid model. First, the oxygen consumption volume was predicted by the OBM model and DNN model, respectively. Second, a more accurate oxygen consumption volume was obtained by integrating the OBM model and DNN model. Finally, the converter oxygen blowing time was calculated according to the oxygen consumption volume and the oxygen supply intensity of each heat. The proposed hybrid model was verified using the actual data collected from an integrated steel plant in China, and compared with multiple linear regression model, OBM model, and neural network model including extreme learning machine, back propagation neural network, and DNN. The test results indicate that the hybrid model with a network structure of 3 hidden layer layers, 32-16-8 neurons per hidden layer, and 0.1 learning rate has the best prediction accuracy and stronger generalization ability compared with other models. The predicted hit ratio of oxygen consumption volume within the error±300 m^(3)is 96.67%;determination coefficient (R^(2)) and root mean square error (RMSE) are0.6984 and 150.03 m^(3), respectively. The oxygen blow time prediction hit ratio within the error±0.6 min is 89.50%;R2and RMSE are0.9486 and 0.3592 min, respectively. As a result, the proposed model can effectively predict the oxygen consumption volume and oxygen blowing time in the converter.
基金supported by the National Natural Science Foundation of China(Grant Nos.52373280,52177014,51977009,52273257).
文摘With the diversified development of big data,detection and precision guidance technologies,electromagnetic(EM)functional materials and devices serving multiple spectrums have become a hot topic.Exploring the multispectral response of materials is a challenging and meaningful scientific question.In this study,MXene/TiO_(2)hybrids with tunable conduction loss and polarization relaxation are fabricated by in situ atomic reconstruction engineering.More importantly,MXene/TiO_(2)hybrids exhibit adjustable spectral responses in the GHz,infrared and visible spectrums,and several EM devices are constructed based on this.An antenna array provides excellent EM energy harvesting in multiple microwave bands,with|S11|up to−63.2 dB,and can be tuned by the degree of bending.An ultra-wideband bandpass filter realizes a passband of about 5.4 GHz and effectively suppresses the transmission of EM signals in the stopband.An infrared stealth device has an emissivity of less than 0.2 in the infrared spectrum at wavelengths of 6-14μm.This work can provide new inspiration for the design and development of multifunctional,multi-spectrum EM devices.
基金supported by the National Key Research and Development Program of China (2022YFB4002100)the development project of Zhejiang Province's "Jianbing" and "Lingyan" (2023C01226)+4 种基金the National Natural Science Foundation of China (22278364, U22A20432, 22238008, 22211530045, and 22178308)the Fundamental Research Funds for the Central Universities (226-2022-00044 and 226-2022-00055)the Science Foundation of Donghai Laboratory (DH-2022ZY0009)the Startup Foundation for Hundred-Talent Program of Zhejiang UniversityScientific Research Fund of Zhejiang Provincial Education Department.
文摘Metal-organic frameworks(MOFs)have been developed as an ideal platform for exploration of the relationship between intrinsic structure and catalytic activity,but the limited catalytic activity and stability has hampered their practical use in water splitting.Herein,we develop a bond length adjustment strategy for optimizing naphthalene-based MOFs that synthesized by acid etching Co-naphthalenedicarboxylic acid-based MOFs(donated as AE-CoNDA)to serve as efficient catalyst for water splitting.AE-CoNDA exhibits a low overpotential of 260 mV to reach 10 mA cm^(−2)and a small Tafel slope of 62 mV dec^(−1)with excellent stability over 100 h.After integrated AE-CoNDA onto BiVO_(4),photocurrent density of 4.3 mA cm^(−2)is achieved at 1.23 V.Experimental investigations demonstrate that the stretched Co-O bond length was found to optimize the orbitals hybridization of Co 3d and O 2p,which accounts for the fast kinetics and high activity.Theoretical calculations reveal that the stretched Co-O bond length strengthens the adsorption of oxygen-contained intermediates at the Co active sites for highly efficient water splitting.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.52130303,52327802,52303101,52173078,51973158)the China Postdoctoral Science Foundation(2023M732579)+2 种基金Young Elite Scientists Sponsorship Program by CAST(No.2022QNRC001)National Key R&D Program of China(No.2022YFB3805702)Joint Funds of Ministry of Education(8091B032218).
文摘Vertically oriented carbon structures constructed from low-dimen-sional carbon materials are ideal frameworks for high-performance thermal inter-face materials(TIMs).However,improving the interfacial heat-transfer efficiency of vertically oriented carbon structures is a challenging task.Herein,an orthotropic three-dimensional(3D)hybrid carbon network(VSCG)is fabricated by depositing vertically aligned carbon nanotubes(VACNTs)on the surface of a horizontally oriented graphene film(HOGF).The interfacial interaction between the VACNTs and HOGF is then optimized through an annealing strategy.After regulating the orientation structure of the VACNTs and filling the VSCG with polydimethylsi-loxane(PDMS),VSCG/PDMS composites with excellent 3D thermal conductive properties are obtained.The highest in-plane and through-plane thermal conduc-tivities of the composites are 113.61 and 24.37 W m^(-1)K^(-1),respectively.The high contact area of HOGF and good compressibility of VACNTs imbue the VSCG/PDMS composite with low thermal resistance.In addition,the interfacial heat-transfer efficiency of VSCG/PDMS composite in the TIM performance was improved by 71.3%compared to that of a state-of-the-art thermal pad.This new structural design can potentially realize high-performance TIMs that meet the need for high thermal conductivity and low contact thermal resistance in interfacial heat-transfer processes.
基金supported by the National Institute on Aging (NIA)National Institutes of Health (NIH)+3 种基金Nos.K99AG065645,R00AG065645R00AG065645-04S1 (to SK)NIH research grants,NINDS,No.R01 NS115834NINDS/NIA,No.R01 NS115834-02S1 (to LG)。
文摘Gamma-aminobutyric acid(GABA)ergic neurons,the most abundant inhibitory neurons in the human brain,have been found to be reduced in many neurological disorders,including Alzheimer's disease and Alzheimer's disease-related dementia.Our previous study identified the upregulation of microRNA-502-3p(miR-502-3p)and downregulation of GABA type A receptor subunitα-1 in Alzheimer's disease synapses.This study investigated a new molecular relationship between miR-502-3p and GABAergic synapse function.In vitro studies were perfo rmed using the mouse hippocampal neuronal cell line HT22 and miR-502-3p agomiRs and antagomiRs.In silico analysis identified multiple binding sites of miR-502-3p at GABA type A receptor subunitα-1 mRNA.Luciferase assay confirmed that miR-502-3p targets the GABA type A receptor subunitα-1 gene and suppresses the luciferase activity.Furthermore,quantitative reve rse transcription-polymerase chain reaction,miRNA in situ hybridization,immunoblotting,and immunostaining analysis confirmed that overexpression of miR-502-3p reduced the GABA type A receptor subunitα-1 level,while suppression of miR-502-3p increased the level of GABA type A receptor subunitα-1 protein.Notably,as a result of the overexpression of miR-502-3p,cell viability was found to be reduced,and the population of necrotic cells was found to be increased.The whole cell patch-clamp analysis of human-GABA receptor A-α1/β3/γ2L human embryonic kidney(HEK)recombinant cell line also showed that overexpression of miR-502-3p reduced the GABA current and overall GABA function,suggesting a negative correlation between miR-502-3p levels and GABAergic synapse function.Additionally,the levels of proteins associated with Alzheimer s disease were high with miR-502-3p overexpression and reduced with miR-502-3p suppression.The present study provides insight into the molecular mechanism of regulation of GABAergic synapses by miR-502-3p.We propose that micro-RNA,in particular miR-502-3p,could be a potential therapeutic to rget to modulate GABAergic synapse function in neurological disorders,including Alzheimer's disease and Alzheimer's diseaserelated dementia.
基金supported by the Natural Science Foundation of China(Grant Nos.42088101 and 42205149)Zhongwang WEI was supported by the Natural Science Foundation of China(Grant No.42075158)+1 种基金Wei SHANGGUAN was supported by the Natural Science Foundation of China(Grant No.41975122)Yonggen ZHANG was supported by the National Natural Science Foundation of Tianjin(Grant No.20JCQNJC01660).
文摘Accurate soil moisture(SM)prediction is critical for understanding hydrological processes.Physics-based(PB)models exhibit large uncertainties in SM predictions arising from uncertain parameterizations and insufficient representation of land-surface processes.In addition to PB models,deep learning(DL)models have been widely used in SM predictions recently.However,few pure DL models have notably high success rates due to lacking physical information.Thus,we developed hybrid models to effectively integrate the outputs of PB models into DL models to improve SM predictions.To this end,we first developed a hybrid model based on the attention mechanism to take advantage of PB models at each forecast time scale(attention model).We further built an ensemble model that combined the advantages of different hybrid schemes(ensemble model).We utilized SM forecasts from the Global Forecast System to enhance the convolutional long short-term memory(ConvLSTM)model for 1–16 days of SM predictions.The performances of the proposed hybrid models were investigated and compared with two existing hybrid models.The results showed that the attention model could leverage benefits of PB models and achieved the best predictability of drought events among the different hybrid models.Moreover,the ensemble model performed best among all hybrid models at all forecast time scales and different soil conditions.It is highlighted that the ensemble model outperformed the pure DL model over 79.5%of in situ stations for 16-day predictions.These findings suggest that our proposed hybrid models can adequately exploit the benefits of PB model outputs to aid DL models in making SM predictions.
