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Preparation,Characterization,and Catalytical Application of MgCoAl-Hydrotalcite-Like Compounds 被引量:12
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作者 Kai Yan Xianmei Xie Jinping Li Xiulan Wang Zhizhong Wang 《Journal of Natural Gas Chemistry》 EI CAS CSCD 2007年第4期371-376,共6页
MgCoAl-hydrotalcite-like compounds (MgCoAI-HTLcs) were synthesized using the coprecipitation method of variable pH values. The effect of each factor on the preparation of HTLcs was discussed systematically, which in... MgCoAl-hydrotalcite-like compounds (MgCoAI-HTLcs) were synthesized using the coprecipitation method of variable pH values. The effect of each factor on the preparation of HTLcs was discussed systematically, which included pH values, mole ratios of Mg2+ to Co2+, the concentrations of the solution, and the temperature and time of the hydrothermal treatment. Besides, the thermal decomposition of MgCoAI-HTLcs was discussed. X-ray diffraction, thermogravimetric analysis, and FT-IR spectroscopy were performed to characterize the MgCoAI-HTLcs samples. The results showed that when the pH = 7.6-8.5 or 5.5-6.2, atomic ratios of (Mg^2++Co2+)/Al^3+ 2 and Mg^2+/Co^2+ ranging from 1.00 to 2.00, temperature and time of hydrothermal treatment being 110℃ and 6 h, unique MgCoAI-HTLcs with high crystallinity could be obtained. When the calcination temperature was up to 250℃, the MgO phase was detected coexisting with Al2O3 and MgAl2O4 was highly spreaded on the derived mixed oxides. The synthesis reaction of benzoin methyl ether with methanol and benzaldehyde was chosen to study the catalytic activity of MgCoAI-HTLcs. The catalyst showed high activity and high stability in the synthesis of benzoin methyl ether in the feasible condition. 展开更多
关键词 MgCoAl-hydrotalcite-like compounds PREPARATION benzoin methyl ether METHANOL BENZALDEHYDE
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The Isoelectric Point and the Points of Zero Charge of Fe-Al-Mg Hydrotalcite-like Compounds
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作者 DongXiangLI WanGuoHOU +2 位作者 ShuPingLI MingTuHAO GaoYongZHANG 《Chinese Chemical Letters》 SCIE CAS CSCD 2004年第2期224-227,共4页
The relation of the isoelectric point (IEP) and the point of zero net charge (PZNC) of the hydrotalcite-like compounds was discussed. It was found that the IEP does not equal to the PZNC and the IEP is higher than th... The relation of the isoelectric point (IEP) and the point of zero net charge (PZNC) of the hydrotalcite-like compounds was discussed. It was found that the IEP does not equal to the PZNC and the IEP is higher than the PZNC. The structural positive charges existing in the HTlc, which cause the difference between the IEP and the PZNC. The effects of the structural positive charges of the HTlc on its IEP and PZNC are the same as the specific adsorption of metal cations. 展开更多
关键词 Isoelectric point points of zero charge potentiometric titration hydrotalcite-like compounds.
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Studies on the Synthesis and the Structure of Ferric Aluminum Magnesium Hydrotalcite-like Compounds
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作者 Shu Ping LI Wan Guo HOU +1 位作者 Peng JIANG Wei Qun ZHU 《Chinese Chemical Letters》 SCIE CAS CSCD 2002年第8期781-782,共2页
The particles of ferric aluminum magnesium hydrotalcite-like compounds (Fe-Al-Mg_HTlc) were synthesized by co-precipitation method. It was found that when n(Fe)/n(Al+Mg+Fe)<0.30 and n(Al)/n(Al+Mg+Fe)<0.30, pure... The particles of ferric aluminum magnesium hydrotalcite-like compounds (Fe-Al-Mg_HTlc) were synthesized by co-precipitation method. It was found that when n(Fe)/n(Al+Mg+Fe)<0.30 and n(Al)/n(Al+Mg+Fe)<0.30, pure HTlc can be formed; when the molar ratio of Al/ (Fe+Al+Mg)>0.30, Al(OH)3 will emerge; when the molar ratio of Fe/(Fe+Al+Mg) >0.30, the amorphous composition will appear. Hence Fe3+ and Al3+ have no concentration superposition effect on the crystal structure of the samples. 展开更多
关键词 hydrotalcite-like compounds CO-PRECIPITATION synthesis.
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CoMnMgAl Hydrotalcite-like Compounds and their Complex Oxides: Facile Synthesis and FCC SO_x Removal
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作者 Jiang Ruiyu Wang Min +5 位作者 Zhu Tao Zhou Yudong Song Xinyu Zhang Feng Ding Liang Gao Jian 《China Petroleum Processing & Petrochemical Technology》 SCIE CAS 2019年第4期29-35,共7页
The X-CoMnMgAl hydrotalcite-like precursors(X-LDHs) were first synthesized by the coprecipitation method using Cl-, CO32-, NO3- and SO42- as the corresponding guest anions, which were further used to prepare X-CoMnMgA... The X-CoMnMgAl hydrotalcite-like precursors(X-LDHs) were first synthesized by the coprecipitation method using Cl-, CO32-, NO3- and SO42- as the corresponding guest anions, which were further used to prepare X-CoMnMgAl complex oxides(X-LDOs) through calcination. The structure and the surface morphology of the as-prepared samples were characterized by FT–IR, XRD, N2 adsorption-desorption and SEM. These as-prepared X-LDOs could act as sulfur-transfer catalysts for desulfurization. The activity of SOx adsorption and regeneration was evaluated via a self-assembled fixed-bed reactor simulating the conditions found in the fluid catalytic cracking units. These four types of sulfur-transfer catalysts with the same phase but different structure displayed the following order of desulfurization efficiency: CO3-LDO >Cl-LDO >NO3-LDO > SO4-LDO. 展开更多
关键词 coprecipitation method hydrotalcite-like compounds sulfur-transfer catalyst desulfurization ef ficiency
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Preparation,Characterization and Application of ZnAlLa-Hydrotalcite-Like Compounds 被引量:3
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作者 Xianmei Xie, Xia An, Xiulan Wang , Zhizhong WangCollege of Chemical Engineering and Technology, Taiyuan University of Technology, Taiyuan 030024, China 《Journal of Natural Gas Chemistry》 EI CAS CSCD 2003年第4期259-263,共5页
The preparation of ZnAlLa-hydrotalcite-like compounds [ZnAlLa-HTLcs] wasstudied. ZnAlLa-HTLcs were synthesized by a method of variable pH with the raw materials ofZn(NO_3)_2, Al(NO_3)_3, La(NO_3)_3, and NaOH. The eS&#... The preparation of ZnAlLa-hydrotalcite-like compounds [ZnAlLa-HTLcs] wasstudied. ZnAlLa-HTLcs were synthesized by a method of variable pH with the raw materials ofZn(NO_3)_2, Al(NO_3)_3, La(NO_3)_3, and NaOH. The eS'ccts of some factors (i.e. pH values, the moleratio of Al^(3+) to La^(3+), temperature and the period of hydrothermal treatment) on thepreparation of HTLcs were discussed systematically. XRD, TG-DTA, FT-IR spectroscopy, and ICP wereperformed to characterize ZnAlLa-HTLcs samples, and the thermal stability of HTLcs was alsodiscussed. It was shown that unique ZnAlLa-HTLcs with high crystallinity can be prepared, under theconditions of pH = 5.5-6.5, n(Zn^(2+))/n(Al^(3+) + La^(3+))=2 and the atomic ratio of La^(3+) toAl^(3+) ranging from 0.07 to 2, hydrothermal treatment at 120 ℃ for 5 h. When the calcination ofthe HTLcs is performed at temperatures above 200 ℃, ZnO phase is detected with Al_2O_3 and La_2O_3spreading on its top. The complex metal oxides derived from ZnAlLa-HTLcs at 500 ℃ have highercatalytic activity and selectivity than those from ZnAl-HTLcs for the esterification of acetic acidwith n-butanol under the same reaction conditions. 展开更多
关键词 layered compound double hydroxide anionic clay HYDROTALCITE ZnAlLa PREPARATION CHARACTERIZATION APPLICATION
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Removal of Cu(Ⅱ) from CuSO4 Aqueous Solution by Mg-Al Hydrotalcite-like Compounds 被引量:4
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作者 臧运波 侯万国 徐洁 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2011年第4期847-852,共6页
Hydrotalcite-like compound (HTlc) with a Mg/AI molar ratio of 2 : 1 was synthesized by using a coprecipitation method and the sorption removal of Cu(Ⅱ) by the Mg-AI HTlc sample from CuSO4 solution was investigat... Hydrotalcite-like compound (HTlc) with a Mg/AI molar ratio of 2 : 1 was synthesized by using a coprecipitation method and the sorption removal of Cu(Ⅱ) by the Mg-AI HTlc sample from CuSO4 solution was investigated. It was found that the Mg-AI HTlc showed a good sorption ability for Cu(Ⅱ) from CuSO4 solution, indicating that the use of hydrotalcite-like compounds as promising inorganic sorbents for the removal of heavy metal ions from water is possible. The sorption kinetics and the sorption isotherm of Cu(Ⅱ) on the HTlc obeyed the pseudo-second order kinetic model and Langmuir equation, respectively. The percent removal of Cu(Ⅱ) by the HT1c was strongly dependent on the initial pH of bulk solution. It increased sharply with the increase of initial pH value in the range of 5-7, and was relatively small in the initial pH range of 4-5, while it reached about 100% after initial pH was higher than 7. The presence of AlCl3 might obviously lower the equilibrium sorption amount (qc) of Cu(Ⅱ) on the HTlc. However, the presences of NaCI and MgCl2 might increase the qe. The presences of ligands (citric acid and EDTA) in the studied concentration range might obviously decrease the qe of Cu(Ⅱ) on the HT1c. The removal mechanism of Cu(Ⅱ) cations by HTlc in the presence of SO4^2- anions may be attributed to the surface-induced precipitation of Cu(Ⅱ) hydroxides and the surface complex adsorption by the linking effect of SO4^2- between the HTlc and Cu(Ⅱ) cations, and the removal ability arising from the surface-induced precipitation is much higher than that from the linking effect of SO4^2-. 展开更多
关键词 ADSORPTION hydrotalcite-like compounds COPPER
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Comparative evaluation of commercial Douchi by different molds:biogenic amines,non-volatile and volatile compounds 被引量:2
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作者 Aijun Li Gang Yang +4 位作者 Zhirong Wang Shenglan Liao Muying Du Jun Song Jianquan Kan 《Food Science and Human Wellness》 SCIE CSCD 2024年第1期434-443,共10页
To provide new insights into the development and utilization of Douchi artificial starters,three common strains(Aspergillus oryzae,Mucor racemosus,and Rhizopus oligosporus)were used to study their influence on the fer... To provide new insights into the development and utilization of Douchi artificial starters,three common strains(Aspergillus oryzae,Mucor racemosus,and Rhizopus oligosporus)were used to study their influence on the fermentation of Douchi.The results showed that the biogenic amine contents of the three types of Douchi were all within the safe range and far lower than those of traditional fermented Douchi.Aspergillus-type Douchi produced more free amino acids than the other two types of Douchi,and its umami taste was more prominent in sensory evaluation(P<0.01),while Mucor-type and Rhizopus-type Douchi produced more esters and pyrazines,making the aroma,sauce,and Douchi flavor more abundant.According to the Pearson and PLS analyses results,sweetness was significantly negatively correlated with phenylalanine,cysteine,and acetic acid(P<0.05),bitterness was significantly negatively correlated with malic acid(P<0.05),the sour taste was significantly positively correlated with citric acid and most free amino acids(P<0.05),while astringency was significantly negatively correlated with glucose(P<0.001).Thirteen volatile compounds such as furfuryl alcohol,phenethyl alcohol,and benzaldehyde caused the flavor difference of three types of Douchi.This study provides theoretical basis for the selection of starting strains for commercial Douchi production. 展开更多
关键词 DOUCHI Starting strains Non-volatile compounds Volatile compounds Sensory evaluation
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Ni-Co/Mg-Al catalyst derived from hydrotalcite-like compound prepared by plasma for dry reforming of methane 被引量:9
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作者 Huali Long Yan Xu +4 位作者 Xiaoqing Zhang Shijing Hu Shuyong Shang Yongxiang Yin Xiaoyan Dai 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2013年第5期733-739,共7页
Ni-Co bimetallic catalysts with different Ni/Co content were derived from cold plasma jet decomposition and reduction of hydrotalcite-like compounds containing Ni,Co,Mg and Al,and their catalytic performance was inves... Ni-Co bimetallic catalysts with different Ni/Co content were derived from cold plasma jet decomposition and reduction of hydrotalcite-like compounds containing Ni,Co,Mg and Al,and their catalytic performance was investigated with dry reforming of methane.Experimental results showed that the hydrotalcite-like precursors could be completely decomposed and partly reduced by cold plasma jet,and the Nicontained catalysts exhibited much higher activity than the catalyst without Ni.Especially,the catalyst with Ni/Co ratio of 8/2 achieved not only the highest conversions of 80.3%and 69.3%for CH4 and CO2,respectively,but also the best stability in 100 h testing.The catalysts were characterized by XRD,XPS,TEM and N2 adsorption techniques,and the results showed that the better performance of the 8Ni2Co bimetallic catalyst was attributed to its higher metal dispersion,smaller metal particle size,as well as the interaction effect between Ni and Co,which were brought by the special catalyst preparation method. 展开更多
关键词 dry reforming of methane Ni-Co bimetallic catalyst cold plasma treatment hydrotalcite-like compound
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Effect of different drying methods on the amino acids,α-dicarbonyls and volatile compounds of rape bee pollen 被引量:1
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作者 Yanxiang Bi Jiabao Ni +6 位作者 Xiaofeng Xue Zidan Zhou Wenli Tian Valérie Orsat Sha Yan Wenjun Peng Xiaoming Fang 《Food Science and Human Wellness》 SCIE CSCD 2024年第1期517-527,共11页
The significant demand for high quality food has motivated us to adopt appropriate processing methods to improve the food nutritional quality and flavors.In this study,the effects of five drying methods,namely,pulsed ... The significant demand for high quality food has motivated us to adopt appropriate processing methods to improve the food nutritional quality and flavors.In this study,the effects of five drying methods,namely,pulsed vacuum drying(PVD),freeze drying(FD),infrared drying(IRD),hot-air drying(HAD)and sun drying(SD)on free amino acids(FAAs),α-dicarbonyl compounds(α-DCs)and volatile compounds(VOCs)in rape bee pollen(RBP)were determined.The results showed that FD significantly released the essential amino acids(EAAs)compared with fresh samples while SD caused the highest loss.Glucosone was the dominantα-DCs in RBP and the highest loss was observed after PVD.Aldehydes were the dominant volatiles of RBP and SD samples contained more new volatile substances(especially aldehydes)than the other four drying methods.Comprehensively,FD and PVD would be potential methods to effectively reduce the quality deterioration of RBP in the drying process. 展开更多
关键词 DRYING Bee pollen Free amino acids α-Dicarbonyl compounds Volatile compounds
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Compound 3k治疗骨关节炎:调控氧化应激通路改善软骨细胞糖酵解的作用机制 被引量:1
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作者 郭素蓉 曹士盛 +2 位作者 穆星彤 杨青 张娟 《中国组织工程研究》 CAS 北大核心 2025年第2期363-370,共8页
背景:骨关节炎现已被认为是一种代谢性疾病,既往研究表明糖酵解在骨关节炎的发生发展中起重要作用。Compound 3k作为一种新型糖酵解小分子抑制剂,具有抗炎及抗肿瘤等功效,因此可靶向糖酵解,有望为骨关节炎治疗提供新的思路。目的:基于... 背景:骨关节炎现已被认为是一种代谢性疾病,既往研究表明糖酵解在骨关节炎的发生发展中起重要作用。Compound 3k作为一种新型糖酵解小分子抑制剂,具有抗炎及抗肿瘤等功效,因此可靶向糖酵解,有望为骨关节炎治疗提供新的思路。目的:基于缺氧诱导因子1α/活性氧的氧化应激通路探究Compound 3k在糖酵解过度活跃所导致的骨关节炎中的作用机制。方法:取对数生长期的ATDC5成软骨细胞,用10 ng/mL白细胞介素1β作用24 h诱导骨关节炎体外细胞模型,以CCK-8法检测不同浓度(0.25,0.5,1,2.5,5,10,15μmol/L)Compound 3k的细胞毒性,选出合适浓度进行后续实验。将软骨细胞随机分为对照组、模型组、治疗组,模型组以10 ng/mL的白细胞介素1β诱导,治疗组以Compound 3k预刺激2 h后与白细胞介素1β共培养,用CCK-8法检测各组细胞增殖情况;用ELISA试剂盒检测各组细胞炎症水平;用试剂盒检测各组细胞活性氧、细胞外乳酸脱氢酶及葡萄糖含量;qRT-PCR及Western blot检测相关炎症因子白细胞介素6、肿瘤坏死因子α及糖酵解相关基因葡萄糖转运蛋白1、甘油醛3-磷酸脱氢酶、单羧酸转运蛋白1和缺氧诱导因子1α的表达水平。结果与结论:①与对照组相比,模型组细胞增殖活性下降、糖酵解水平活跃,表现为细胞外乳酸脱氢酶含量增加(P<0.001),葡萄糖含量减少(P<0.001),相关炎症因子白细胞介素6(P<0.0001)及肿瘤坏死因子α(P<0.001),糖酵解相关基因葡萄糖转运蛋白1(P<0.001)、甘油醛3-磷酸脱氢酶(P<0.001)、单羧酸转运蛋白1(P<0.001)及缺氧诱导因子1α(P<0.001)的表达水平均上调,并伴随氧化应激,活性氧过量产生。②与模型组相比,Compound 3k的治疗有效提高细胞增殖活性,抑制过度活跃的糖酵解水平的同时,抑制了骨关节炎软骨细胞炎症(P<0.001)及糖酵解相关基因的表达(P<0.001),且抑制氧化应激,缺氧诱导因子1α的表达水平下调(P<0.0001),活性氧水平下降。③上述结果证实,Compound 3k抑制了白细胞介素1β诱导的软骨细胞炎症,其机制可能与糖酵解及缺氧诱导因子1α/活性氧介导的氧化应激有关。 展开更多
关键词 骨关节炎 糖酵解 compound 3k 氧化应激 HIF-1α/ROS ATDC5细胞 葡萄糖代谢 白细胞介素1Β 小分子药物
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Significant contributions of the petroleum industry to volatile organic compounds and ozone pollution:Insights from year-long observations in the Yellow River Delta 被引量:1
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作者 Jinghao Tang Hengqing Shen +7 位作者 Hong Li Yuanyuan Ji Xuelian Zhong Min Zhao Yuhong Liu Mingzhi Guo Fanyi Shang Likun Xue 《Atmospheric and Oceanic Science Letters》 CSCD 2024年第6期39-44,共6页
The petroleum industry is a significant source of anthropogenic volatile organic compounds(VOCs),but up to now,its exact impact on urban VOCs and ozone(O_(3))remains unclear.This study conducted year-long VOC ob-serva... The petroleum industry is a significant source of anthropogenic volatile organic compounds(VOCs),but up to now,its exact impact on urban VOCs and ozone(O_(3))remains unclear.This study conducted year-long VOC ob-servations in Dongying,China,a petroleum industrial region.The VOCs from the petroleum industry(oil and gas volatilization and petrochemical production)were identified by employing the positive matrix factorization model,and their contribution to O_(3) formation was quantitatively evaluated using an observation-based chemical box model.The observed annual average concentration of VOCs was 68.6±63.5 ppbv,with a maximum daily av-erage of 335.3 ppbv.The petroleum industry accounted for 66.5%of total VOCs,contributing 54.9%from oil and gas evaporation and 11.6%from petrochemical production.Model results indicated that VOCs from the petroleum industry contributed to 31%of net O_(3) production,with 21.3%and 34.2%contributions to HO_(2)+NO and RO_(2)+NO pathways,respectively.The larger impact on the RO_(2) pathway is primarily due to the fact that OH+VOCs ac-count for 86.9%of the primary source of RO_(2).This study highlights the critical role of controlling VOCs from the petroleum industry in urban O_(3) pollution,especially those from previously overlooked low-reactivity alkanes. 展开更多
关键词 Petroleum industry Volatile organic compounds Ozone pollution Positive matrix factorization Observation-based model
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Role of methoxy and C_(α)-based substituents in electrochemical oxidation mechanisms and bond cleavage selectivity of β-O-4 lignin model compounds 被引量:1
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作者 Yang Zhou Qiang Zeng +3 位作者 Hongyan He Kejia Wu Fuqiao Liu Xuehui Li 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第1期114-125,共12页
In order to better understand the specific substituent effects on the electrochemical oxidation process of β-O-4 bond, a series of methoxyphenyl type β-O-4 dimer model compounds with different localized methoxyl gro... In order to better understand the specific substituent effects on the electrochemical oxidation process of β-O-4 bond, a series of methoxyphenyl type β-O-4 dimer model compounds with different localized methoxyl groups, including 2-(2-methoxyphenoxy)-1-phenylethanone, 2-(2-methoxyphenoxy)-1-phenylethanol, 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethanone, 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethanol, 2-(2,6-dimethoxyphenoxy)-1-(4-methoxyphenyl)ethanone, 2-(2,6-dimethoxyphenoxy)-1-(4-methoxyphenyl)ethanol have been selected and their electrochemical properties have been studied experimentally by cyclic voltammetry, and FT-IR spectroelectrochemistry. Combining with electrolysis products distribution analysis and density functional theory calculations, oxidation mechanisms of all six model dimers have been explored. In particular, a total effect from substituents of both para-methoxy(on the aryl ring closing to Cα) and Cα-OH on the oxidation mechanisms has been clearly observed, showing a significant selectivity on the Cα-Cβbond cleavage induced by electrochemical oxidations. 展开更多
关键词 Lignin model compounds β-O-4 dimers Electrochemical oxidation Oxidation mechanisms Substituent effect
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Modern approaches for detection of volatile organic compounds in metabolic studies focusing on pathogenic bacteria:Current state of the art 被引量:2
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作者 Karolina Zuchowska Wojciech Filipiak 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2024年第4期483-505,共23页
Pathogenic microorganisms produce numerous metabolites,including volatile organic compounds(VOCs).Monitoring these metabolites in biological matrices(e.g.,urine,blood,or breath)can reveal the presence of specific micr... Pathogenic microorganisms produce numerous metabolites,including volatile organic compounds(VOCs).Monitoring these metabolites in biological matrices(e.g.,urine,blood,or breath)can reveal the presence of specific microorganisms,enabling the early diagnosis of infections and the timely implementation of tar-geted therapy.However,complex matrices only contain trace levels of VOCs,and their constituent com-ponents can hinder determination of these compounds.Therefore,modern analytical techniques enabling the non-invasive identification and precise quantification of microbial VOCs are needed.In this paper,we discuss bacterial VOC analysis under in vitro conditions,in animal models and disease diagnosis in humans,including techniques for offline and online analysis in clinical settings.We also consider the advantages and limitations of novel microextraction techniques used to prepare biological samples for VOC analysis,in addition to reviewing current clinical studies on bacterial volatilomes that address inter-species in-teractions,the kinetics of VOC metabolism,and species-and drug-resistance specificity. 展开更多
关键词 Volatile organic compounds Pathogenic bacteria metabolites Metabolomics Microextraction techniques Gas chromatography-mass spectrometry In vivo breath analysis In vitro model
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Assessment of electrostatic discharge sensitivity of nitrogen-rich heterocyclic energetic compounds and their salts as high energy-density dangerous compounds:A study of structural variables
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作者 Mohammad Hossein Keshavarz Sedigheh Heydari Bani +1 位作者 Reza Bakhtiari Seyyed Hesamodin Hosseini 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第9期15-22,共8页
Nitrogen-rich heterocyclic energetic compounds(NRHECs)and their salts have witnessed widespread synthesis in recent years.The substantial energy-density content within these compounds can lead to potentially dangerous... Nitrogen-rich heterocyclic energetic compounds(NRHECs)and their salts have witnessed widespread synthesis in recent years.The substantial energy-density content within these compounds can lead to potentially dangerous explosive reactions when subjected to external stimuli such as electrical discharge.Therefore,developing a reliable model for predicting their electrostatic discharge sensitivity(ESD)becomes imperative.This study proposes a novel and straightforward model based on the presence of specific groups(-NH_(2) or-NH-,-N=N^(+)-O^(-)and-NNO_(2),-ONO_(2) or-NO_(2))under certain conditions to assess the ESD of NRHECs and their salts,employing interpretable structural parameters.Utilizing a comprehensive dataset comprising 54 ESD measurements of NRHECs and their salts,divided into 49/5 training/test sets,the model achieves promising results.The Root Mean Square Error(RMSE),Mean Absolute Error(MAE),and Maximum Error for the training set are reported as 0.16 J,0.12 J,and 0.5 J,respectively.Notably,the ratios RMSE(training)/RMSE(test),MAE(training)/MAE(test),and Max Error(training)/Max Error(test)are all greater than 1.0,indicating the robust predictive capabilities of the model.The presented model demonstrates its efficacy in providing a reliable assessment of ESD for the targeted NRHECs and their salts,without the need for intricate computer codes or expert involvement. 展开更多
关键词 Electrostatic discharge sensitivity Heterocyclic energetic compounds containing azole compound Interpretable structural parameter Safety
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Organic Compounds Possessing the Plastic Crystalline Phase: Calculation of Their Fusion Enthalpies
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作者 Mikhail Yu. Gorbachev Natalia N. Gorinchoy 《International Journal of Organic Chemistry》 2024年第3期93-106,共14页
For the first time, for different organic and inorganic compounds possessing the plastic crystalline phase, a new semiempirical equation describing dependence of their fusion enthalpies on such physico-chemical quanti... For the first time, for different organic and inorganic compounds possessing the plastic crystalline phase, a new semiempirical equation describing dependence of their fusion enthalpies on such physico-chemical quantities as normal melting temperature, surface tension, molar volume and critical molar volume is received on the base of the principle of corresponding states and the energy equipartition theorem. Moreover, the proposed equation allows one to take into account the particularities of one-particle molecular rotation in the plastic crystalline phase. 展开更多
关键词 Fusion Enthalpies Calculation Organic compounds Inorganic compounds Plastic Crystalline Phases
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Natural compounds improve diabetic nephropathy by regulating the TLR4 signaling pathway
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作者 Jiabin Wu Ke Li +3 位作者 Muge Zhou Haoyang Gao Wenhong Wang Weihua Xiao 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2024年第8期1125-1139,共15页
Diabetic nephropathy(DN),a severe complication of diabetes,is widely recognized as a primary contributor to end-stage renal disease.Recent studies indicate that the inflammation triggered by Tolllike receptor 4(TLR4)i... Diabetic nephropathy(DN),a severe complication of diabetes,is widely recognized as a primary contributor to end-stage renal disease.Recent studies indicate that the inflammation triggered by Tolllike receptor 4(TLR4)is of paramount importance in the onset and progression of DN.TLR4 can bind to various ligands,including exogenous ligands such as proteins and polysaccharides from bacteria or viruses,as well as endogenous ligands such as biglycan,fibrinogen,and hyaluronan.In DN,the expression or release of TLR4-related ligands is significantly elevated,resulting in excessive TLR4 activation and increased production of proinflammatory cytokines through downstream signaling pathways.This process is closely associated with the progression of DN.Natural compounds are biologically active products derived from natural sources that have advantages in the treatment of certain diseases.Various types of natural compounds,including alkaloids,flavonoids,polyphenols,terpenoids,glycosides,and polysaccharides,have demonstrated their ability to improve DN by affecting the TLR4 signaling pathway.In this review,we summarize the mechanism of action of TLR4 in DN and the natural compounds that can ameliorate DN by modulating the TLR4 signaling pathway.We specifically highlight the potential of compounds such as curcumin,paclitaxel,berberine,and ursolic acid to inhibit the TLR4 signaling pathway,which provides an important direction of research for the treatment of DN. 展开更多
关键词 Diabetic nephropathy Toll-like receptor 4 Natural compounds INFLAMMATION
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Nutritional values,bioactive compounds and health benefits of purslane(Portulaca oleracea L.):a comprehensive review
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作者 Yanxi Li Longgao Xiao +3 位作者 Huan Yan Mingyi Wu Xiaojiang Hao Haiyang Liu 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第5期2480-2501,共22页
Portulaca oleracea L.,commonly known as purslane,is a worldwide weed species belonging to the family Portulacaceae and has been known as“Global Panacea”.As one of the most widely consumed green vegetables and medici... Portulaca oleracea L.,commonly known as purslane,is a worldwide weed species belonging to the family Portulacaceae and has been known as“Global Panacea”.As one of the most widely consumed green vegetables and medicinal plants around the world,it has recently been re-evaluated as a potential“new crop”due to the properties that differentiate it as one of the best vegetable sources of omega-3 fatty acid(α-linolenic acid),as well as a variety of nutrients and phytochemicals.Accordingly,emerging research has found that purslane exhibits health-promoting properties like anti-inflammatory,anti-hyperglycemic,antioxidant,neuroprotective,and immunomodulatory.These findings suggest that this species possesses a potential using as a dietary supplement beyond potherb and traditional medicine.This review systematically summarizes the up-to-date research carried out on purslane,including the nutritional compositions,bioactive compounds,and health benefits it exerts as well as limitations,challenges,and future directions of research.Finally,we hope that this review would provide purslane with a comprehensive reference and future scope as functional and health-promoting food for disease prevention and treatment. 展开更多
关键词 Purslane Nutritional compositions Bioactive compounds POLYSACCHARIDES Functional foods
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Antidiabetic Properties of Bidens pilosa and Its Polyacetylenic Compounds for Management of Diabetes: Systematic Review
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作者 Kenneth Waititu Caroline Mugo +1 位作者 Daisy Nyawira Peter Mwethera 《Journal of Biosciences and Medicines》 2024年第2期164-179,共16页
Bidens pilosa is a member of the Asteraceae family that is widely distributed across the tropics. It has been utilized by different communities both as food and medicinal herb. This plant and its polyacetylenic compou... Bidens pilosa is a member of the Asteraceae family that is widely distributed across the tropics. It has been utilized by different communities both as food and medicinal herb. This plant and its polyacetylenic compounds hold potential as a natural antidiabetic intervention that can be used to combat this global public health problem. Bioactive compounds found in this plant constitute promising interventions for combating obesity which is a major risk factor for the development of type 2 diabetes. These phytocompounds can work independently or synergistically to modulate appetite, lipase activity, adipogenesis and adipocyte apoptosis. However, the efficacy, mode of action and scope of management of diabetes by these compounds remains elusive. The current review aims to summarize data on efficacy in the management of diabetes, an antidiabetic candidate polyacetylenic compound and possible biological activities as an antidiabetic agent from the available literature. Much emphasis has been directed to cytopiloyne as a representative of polyacetylenic compounds extracted from Bidens pilosa and its activity on diabetic animal models. The majority of the studies conducted on animal models described antidiabetic mechanisms that range from hypoglycemic to secretagogue activity of cytopiloyne in a dose-dependent manner. A clinical trial pilot indicated improved glycemic control of Bidens pilosa formulation among diabetic patients in the study. Bidens pilosa and its compounds are highly potent antidiabetic agent(s) that should be graduated to an intervention for management of diabetes through pre-clinical and clinical trials to elucidate its efficacy and safety. 展开更多
关键词 ANTIDIABETIC Cytopiloyne Bidens pilosa Polyacetylenic compounds
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Bioactive compounds in Hericium erinaceus and their biological properties:a review
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作者 Yue Qiu Genglan Lin +4 位作者 Weiming Liu Fuming Zhang Robert J.Linhardt Xingli Wang Anqiang Zhang 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第4期1825-1844,共20页
Hericium erinaceus is a nutritious edible and medicinal fungi,rich in a variety of functional active ingredients,with various physiological functions such as antioxidation,anticancer,and enhancing immunity.It is also ... Hericium erinaceus is a nutritious edible and medicinal fungi,rich in a variety of functional active ingredients,with various physiological functions such as antioxidation,anticancer,and enhancing immunity.It is also effective in protecting the digestive system and preventing neurodegenerative diseases.In this review paper,we summarize the sources,structures and efficacies of the main active components in H.erinaceus fruiting body,mycelium,and culture media,and update the latest research progress on their biological activities and the related molecular mechanisms.Based on this information,we provide detailed challenges in current research,industrialization and information on the active ingredients of H.erinaceus.Perspectives for future studies and new applications of H.erinaceus are proposed. 展开更多
关键词 Hericium erinaceus Bioactive compounds Biological activities ANTIOXIDATION NEUROPROTECTION IMMUNOREGULATION
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Multiple roles of arsenic compounds in phase separation and membraneless organelles formation determine their therapeutic efficacy in tumors
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作者 Meiyu Qu Qiangqiang He +5 位作者 Hangyang Bao Xing Ji Tingyu Shen Muhammad Qasim Barkat Ximei Wu Ling-Hui Zeng 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2024年第8期1110-1124,共15页
Arsenic compounds are widely used for the therapeutic intervention of multiple diseases.Ancient pharmacologists discovered the medicinal utility of these highly toxic substances,and modern pharmacologists have further... Arsenic compounds are widely used for the therapeutic intervention of multiple diseases.Ancient pharmacologists discovered the medicinal utility of these highly toxic substances,and modern pharmacologists have further recognized the specific active ingredients in human diseases.In particular,Arsenic trioxide(ATO),as a main component,has therapeutic effects on various tumors(including leukemia,hepatocellular carcinoma,lung cancer,etc.).However,its toxicity limits its efficacy,and controlling the toxicity has been an important issue.Interestingly,recent evidence has pointed out the pivotal roles of arsenic compounds in phase separation and membraneless organelles formation,which may determine their toxicity and therapeutic efficacy.Here,we summarize the arsenic compoundsregulating phase separation and membraneless organelles formation.We further hypothesize their potential involvement in the therapy and toxicity of arsenic compounds,highlighting potential mechanisms underlying the clinical application of arsenic compounds. 展开更多
关键词 Arsenic compounds Phase separation Membraneless organelles PML Stress granules
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