Objective:The purpose of this study was to understand the clinical efficacy of Xingnaojing Injection in the treatment of cerebral hemorrhage in the real world.Methods:The hospitalized patients with cerebral hemorrhage...Objective:The purpose of this study was to understand the clinical efficacy of Xingnaojing Injection in the treatment of cerebral hemorrhage in the real world.Methods:The hospitalized patients with cerebral hemorrhage mainly diagnosed in the hospital information system(HIS)of 223 A hospitals in the country were selected as the research subjects.The patients with cerebral hemorrhage using Xingnaojing Injection were used as the Xingnaojing group.The group was matched with the same sex,age±5 years old,similar hospital admission conditions,matched according to 1:1 ratio.The patients with cerebral hemorrhage without using Xingnaojing Injection were used as the control group,and the therapeutic effects after treatment were used as outcome evaluation index.A total of 3 Logistic regression methods were used to analyze the effects of Xingnaojing Injection in the treatment outcome of patients with cerebral hemorrhage.Results:The statistical results showed that there was a difference in the efficacy of the treatment of cerebral hemorrhage by the use of Xingnaojing Injection(P<0.05).Conclusion:Based on the existing analytical methods and data,the effects of Xingnaojing Injection on cerebral hemorrhage are better than that of the non-use control group,which provides reference for the clinical drug use of cerebral hemorrhage.展开更多
目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的...目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的方法为患者进行治疗,观察组采用软通道穿刺引流术为患者进行治疗,比较两组治疗效果。结果与对照组比较,观察组中等量高血压脑出血患者的救治成功率更高,治疗有效性更高,术后并发症发生率更低,且经过治疗后的临床神经功能缺损评分(national institute of health stroke scale,NIHSS)更低,生活质量和睡眠质量更高(P<0.05)。结论针对中等量高血压脑出血患者,采取软通道穿刺引流术的效果更优,患者的治疗有效性和神经功能状况得到改善,并发症情况较低,且患者治疗后生活质量和睡眠质量得到提升,治疗优势突出,可在临床大量推广。展开更多
基金2015 Research Project of Chinese Medicine Industry(No.201507003-8)Basic Research Funding Project of Central Public Welfare Research Institutes(Z0439)+1 种基金Science and Technology Innovation Team of China Academy of Chinese Medical Sciences(PY1303)Research Funding Project For Graduate Education Teaching Reform of China Academy of Chinese Medical Sciences(JG201703)
文摘Objective:The purpose of this study was to understand the clinical efficacy of Xingnaojing Injection in the treatment of cerebral hemorrhage in the real world.Methods:The hospitalized patients with cerebral hemorrhage mainly diagnosed in the hospital information system(HIS)of 223 A hospitals in the country were selected as the research subjects.The patients with cerebral hemorrhage using Xingnaojing Injection were used as the Xingnaojing group.The group was matched with the same sex,age±5 years old,similar hospital admission conditions,matched according to 1:1 ratio.The patients with cerebral hemorrhage without using Xingnaojing Injection were used as the control group,and the therapeutic effects after treatment were used as outcome evaluation index.A total of 3 Logistic regression methods were used to analyze the effects of Xingnaojing Injection in the treatment outcome of patients with cerebral hemorrhage.Results:The statistical results showed that there was a difference in the efficacy of the treatment of cerebral hemorrhage by the use of Xingnaojing Injection(P<0.05).Conclusion:Based on the existing analytical methods and data,the effects of Xingnaojing Injection on cerebral hemorrhage are better than that of the non-use control group,which provides reference for the clinical drug use of cerebral hemorrhage.
文摘目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的方法为患者进行治疗,观察组采用软通道穿刺引流术为患者进行治疗,比较两组治疗效果。结果与对照组比较,观察组中等量高血压脑出血患者的救治成功率更高,治疗有效性更高,术后并发症发生率更低,且经过治疗后的临床神经功能缺损评分(national institute of health stroke scale,NIHSS)更低,生活质量和睡眠质量更高(P<0.05)。结论针对中等量高血压脑出血患者,采取软通道穿刺引流术的效果更优,患者的治疗有效性和神经功能状况得到改善,并发症情况较低,且患者治疗后生活质量和睡眠质量得到提升,治疗优势突出,可在临床大量推广。
