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Evaluation of the water conservation function in the Ili River Delta of Central Asia based on the InVEST model 被引量:2
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作者 CAO Yijie MA Yonggang +2 位作者 BAO Anming CHANG Cun LIU Tie 《Journal of Arid Land》 SCIE CSCD 2023年第12期1455-1473,共19页
The Ili River Delta(IRD)is an ecological security barrier for the Lake Balkhash and an important water conservation area in Central Asia.In this study,we selected the IRD as a typical research area,and simulated the w... The Ili River Delta(IRD)is an ecological security barrier for the Lake Balkhash and an important water conservation area in Central Asia.In this study,we selected the IRD as a typical research area,and simulated the water yield and water conservation from 1975 to 2020 using the water yield module of the Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)model.We further analyzed the temporal and spatial variations in the water yield and water conservation in the IRD from 1975 to 2020,and investigated the main driving factors(precipitation,potential evapotranspiration,land use/land cover change,and inflow from the Ili River)of the water conservation variation based on the linear regression,piecewise linear regression,and Pearson's correlation coefficient analyses.The results indicated that from 1975 to 2020,the water yield and water conservation in the IRD showed a decreasing trend,and the spatial distribution pattern was"high in the east and low in the west";overall,the water conservation of all land use types decreased slightly.The water conservation volume of grassland was the most reduced,although the area of grassland increased owing to the increased inflow from the Ili River.At the same time,the increased inflow has led to the expansion of wetland areas,the improvement of vegetation growth,and the increase of regional evapotranspiration,thus resulting in an overall reduction in the water conservation.The water conservation depth and precipitation had similar spatial distribution patterns;the change in climate factors was the main reason for the decline in the water conservation function in the delta.The reservoir in the upper reaches of the IRD regulated runoff into the Lake Balkhash,promoted vegetation restoration,and had a positive effect on the water conservation;however,this positive effect cannot offset the negative effect of enhanced evapotranspiration.These results provide a reference for the rational allocation of water resources and ecosystem protection in the IRD. 展开更多
关键词 water conservation function water yield Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)model climate change land use/land cover change(LUCC) ili River Delta Lake Balkhash
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ILIS数据库的建立浅说 被引量:1
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作者 陈晰明 《晋图学刊》 1994年第2期63-65,55,共4页
图书馆计算机综合管理系统是图书馆自动化的重要组成部分.近年来我国图书馆集成系统的研制工作取得了很大的进展,而国外的应用已趋于成熟.为了节省人力和时间,少做重复的工作,引进现成的图书馆集成管理系统,可以加快图书馆自动化的进程... 图书馆计算机综合管理系统是图书馆自动化的重要组成部分.近年来我国图书馆集成系统的研制工作取得了很大的进展,而国外的应用已趋于成熟.为了节省人力和时间,少做重复的工作,引进现成的图书馆集成管理系统,可以加快图书馆自动化的进程.在国家教委的组织下,我国十几所院校图书馆同时引进了日本富士通公司的K系列小型计算机及图书馆综合管理系统(ILIS),以此作为硬件和软件来实现图书馆计算机管理.在此基础上,做好ILIS数据库的建设,使K系列及ILIS尽快投入运行,把图书馆自动化工作提高到一个新的水平,就成为当务之急. 展开更多
关键词 数据库 信息数据文件 图书馆自动化 馆藏数据 iliS 图书馆集成管理系统 书目数据 中文图书书目 图书馆计算机管理 综合管理系统
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用FoxPro处理ILIS流通数据
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作者 张晓颖 郑春 《大学图书馆学报》 CSSCI 北大核心 1998年第4期53-53,共1页
描述了如何利用FosPro来处理ILIS的流通数据。
关键词 FOXPRO 数据管理 iliS 流通数据 图书馆管理系统
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基于ILI算法的数字D类放大器调制模块 被引量:5
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作者 郑杰 王京梅 +1 位作者 李莉 孙俊 《电路与系统学报》 CSCD 北大核心 2012年第5期26-30,25,共6页
为了降低音频数字D类放大器的谐波失真,该文提出了迭代线性内插(ILI)算法。该算法基于拉格朗日多项式和交点判断规则实现,每周期仅需计算N个样本即可完成2N阶内插,显著降低了高阶伪自然采样PWM(PNPWM)调制的实现代价。该文对交点判断规... 为了降低音频数字D类放大器的谐波失真,该文提出了迭代线性内插(ILI)算法。该算法基于拉格朗日多项式和交点判断规则实现,每周期仅需计算N个样本即可完成2N阶内插,显著降低了高阶伪自然采样PWM(PNPWM)调制的实现代价。该文对交点判断规则进行了证明,并给出了ILI算法的硬件实现框图。该文使用FPGA构建了一个基于ILI算法的16阶立体声音频数字D类放大器调制模块。经过RMAA软件测试,该调制模块的THD@1kHz指标达到了0.0070%,证实了ILI算法的有效性。 展开更多
关键词 数字D类放大器 PNPWM调制 高阶线性内插 拉格朗日多项式 交点判断规则 ili算法
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STM32驱动ILI9325显示字符串的方法 被引量:3
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作者 李雪伟 张立勋 唐小景 《煤矿机械》 北大核心 2011年第10期263-265,共3页
介绍了液晶主控ILI9325的控制时序图;给出了STM32初始化的过程和ILI9325的配置步骤;重点讲述了一种基于8位数据传输模式的字符串显示的基本原理和配置方法。最终实现了任意字符(包括汉字、字母和符号)的显示。
关键词 显示 字符串 STM32 ili9325
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Quantitative Assessment of the Relative Contributions of Climate and Human Factors to Net Primary Productivity in the Ili River Basin of China and Kazakhstan 被引量:2
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作者 LIU Liang GUAN Jingyun +3 位作者 HAN Wanqiang JU Xifeng MU Chen ZHENG Jianghua 《Chinese Geographical Science》 SCIE CSCD 2022年第6期1069-1082,共14页
It is necessary to quantitatively study the relationship between climate and human factors on net primary productivity(NPP)inorder to understand the driving mechanism of NPP and prevent desertification.This study inve... It is necessary to quantitatively study the relationship between climate and human factors on net primary productivity(NPP)inorder to understand the driving mechanism of NPP and prevent desertification.This study investigated the spatial and temporal differentiation features of actual net primary productivity(ANPP)in the Ili River Basin,a transboundary river between China and Kazakhstan,as well as the proportional contributions of climate and human causes to ANPP variation.Additionally,we analyzed the pixel-scale relationship between ANPP and significant climatic parameters.ANPP in the Ili River Basin increased from 2001 to 2020 and was lower in the northeast and higher in the southwest;furthermore,it was distributed in a ring around the Tianshan Mountains.In the vegetation improvement zone,human activities were the dominant driving force,whereas in the degraded zone,climate change was the primary major driving force.The correlation coefficients of ANPP with precipitation and temperature were 0.322 and 0.098,respectively.In most areas,there was a positive relationship between vegetation change,temperature and precipitation.During 2001 to 2020,the basin’s climatic change trend was warm and humid,which promoted vegetation growth.One of the driving factors in the vegetation improvement area was moderate grazing by livestock. 展开更多
关键词 net primary productivity(NPP) actual net primary productivity(ANPP) climate change human activities ili River Basin
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Spatial Variability of Soil Carbon to Nitrogen Ratio and Its Driving Factors in Ili River Valley,Xinjiang,Northwest China 被引量:4
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作者 SUN Guojun LI Weihong +1 位作者 ZHU Chenggang CHEN Yaning 《Chinese Geographical Science》 SCIE CSCD 2017年第4期529-538,共10页
Soil carbon to nitrogen(C/N) ratio is one of the most important variables reflecting soil quality and ecological function,and an indicator for assessing carbon and nitrogen nutrition balance of soils.Its variation ref... Soil carbon to nitrogen(C/N) ratio is one of the most important variables reflecting soil quality and ecological function,and an indicator for assessing carbon and nitrogen nutrition balance of soils.Its variation reflects the carbon and nitrogen cycling of soils.In order to explore the spatial variability of soil C/N ratio and its controlling factors of the Ili River valley in Xinjiang Uygur Autonomous Region,Northwest China,the traditional statistical methods,including correlation analysis,geostatistic alanalys and multiple regression analysis were used.The statistical results showed that the soil C/N ratio varied from 7.00 to 23.11,with a mean value of 10.92,and the coefficient of variation was 31.3%.Correlation analysis showed that longitude,altitude,precipitation,soil water,organic carbon,and total nitrogen were positively correlated with the soil C/N ratio(P < 0.01),whereas negative correlations were found between the soil C/N ratio and latitude,temperature,soil bulk density and soil p H.Ordinary Cokriging interpolation showed that r and ME were 0.73 and 0.57,respectively,indicating that the prediction accuracy was high.The spatial autocorrelation of the soil C/N ratio was 6.4 km,and the nugget effect of the soil C/N ratio was 10% with a patchy distribution,in which the area with high value(12.00–20.41) accounted for 22.6% of the total area.Land uses changed the soil C/N ratio with the order of cultivated land > grass land > forest land > garden.Multiple regression analysis showed that geographical and climatic factors,and soil physical and chemical properties could independently explain 26.8%and 55.4% of the spatial features of soil C/N ratio,while human activities could independently explain 5.4% of the spatial features only.The spatial distribution of soil C/N ratio in the study has important reference value for managing soil carbon and nitrogen,and for improving ecological function to similar regions. 展开更多
关键词 soil C/N ratio spatial variability geostatistical analysis Cokriging interpolation multiple regression analysis ili River valley
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Genetic Similarity among Varieties of Armeniaca vulgaris Shushanggan in Ili
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作者 Shuying CHEN Guizhi CONG +4 位作者 Jin WANG Jun LIU You SHI Deming QIN Abudu·Salamu 《Asian Agricultural Research》 2021年第3期37-39,共3页
[Objectives]To analyze the genetic similarity among varieties of Armeniaca vulgaris Shushanggan in Ili.[Methods]The genetic distance among 13 A.vulgaris Shushanggan varieties was compared at the DNA molecular level,an... [Objectives]To analyze the genetic similarity among varieties of Armeniaca vulgaris Shushanggan in Ili.[Methods]The genetic distance among 13 A.vulgaris Shushanggan varieties was compared at the DNA molecular level,and clustering analysis was performed on them.[Results]The 13 varieties of A.vulgaris Shushanggan were classified into four clusters.The first cluster included Shushang Ganxing 1,Shushang Ganxing 4,Gongliu Yexing and Zhenzhu Youxing,and the similarity coefficient between Shushang Ganxing 1 and Shushang Ganxing4 reached 0.808;the second cluster were Shushang Ganxing 2,Shushang Ganxing 3 and Liguangxing,and the similarity coefficient between Shushang Ganxing 2 and Shushang Ganxing 3 was 0.846[1];Ili Baixing,61 Tuan Guyexing,Chaxian Yexing and Huocheng Yexing were classified into the third cluster,and the similarity coefficient between Ili Baixing and 61 Tuan Guyexing was 0.692;and the fourth cluster included Shushang Ganxing W1 and Yixian Yexing,between which the similarity coefficient was 0.692.[Conclusions]This will lay a foundation for the research of variety identification and genetic structure of A.vulgaris Shushanggan. 展开更多
关键词 Armeniaca vulgaris Shushanggan VARIETY Gene similarity ili
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Threats and Avoidance Measures of Frost Damage of‘Shushanggan’Apricot in the Ili River Valley
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作者 Guizhi CONG Shuying CHEN +2 位作者 Yuping MA Jin WANG You SHI 《Asian Agricultural Research》 2021年第5期26-30,共5页
[Objectives]To explore the threat factors of frost damage to‘Shushanggan’Apricot in the Ili River Valley,and to provide measures for avoiding frost damage.[Methods]Based on the meteorological data of the Ili River V... [Objectives]To explore the threat factors of frost damage to‘Shushanggan’Apricot in the Ili River Valley,and to provide measures for avoiding frost damage.[Methods]Based on the meteorological data of the Ili River Valley counties and cities during the 12 years from 2010 to 2021 and using the critical low temperature of‘Shushanggan’Apricot as the main factor,we comprehensively analyzed the threats of low temperature in winter in January and late frost in April in spring in the Ili River Valley.[Results]During the 12 years,there were 4 years of low temperature below the critical(-26—-28℃)of‘Shushanggan’Apricot in the Ili River Valley counties and cities in January,accounting for 33.3%,and a total of 59 d.The frequency of occurrence was:Nilka County>Qapqal County>Yining City>Gongliu County>Huocheng County>Khorgos City>Yining County>Tekes County>Xinyuan County.In April,there were 9 years with a low temperature below the critical temperature(-0.6℃)flowering and fruit setting of‘Shushanggan’Apricot,accounting for 75%,and a total of 134 d.The frequency of occurrence was:Nilka County>Tekes County>Gongliu County>Yining County>Huocheng County>Khorgos City>Xinyuan County>Yining City>Qapqal County.The low temperature threats of‘Shushanggan’Apricot suitable cultivation areas were ranked as follows:Nilka County>Gongliu County>Tekes County>Qapqal County>Huocheng County>Yining City>Yining County>Khorgos City>Xinyuan County.Combined with the observation and survey of frost damage on the spot,we comprehensively analyzed and evaluated the cultivation area of‘Shushanggan’Apricot in the Ili River Valley:three counties(Nilka County,Gongliu County,and Tekes County)in the eastern region,except Xinyuan County,suffered frequent late frost damage,are suitable areas for the cultivation of‘Shushanggan’Apricot;three counties and two cities in the western region(Qapqal County,Huocheng County,Yining City,Yining County,Khorgos City)and Xinyuan County in the eastern region are suitable areas for‘Shushanggan’Apricot.The inversion zone at an altitude of 820-1100 in the valley is the superior area for‘Shushanggan’Apricot.[Conclusions]We explored the suitable areas in the origin area of‘Shushanggan’Apricot,and came up with measures to avoid frost damage,to provide a reference for the development of‘Shushanggan’Apricot. 展开更多
关键词 ‘Shushanggan’Apricot ili River Valley Frost damage Threats Avoidance measures
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TASTING ILI
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《China Report ASEAN》 2020年第9期29-31,共3页
Food can represent the past,mark the places we visited and remind us of the people we met,so each new bite revives warm memories.Xinjiang,a Good Place is a popular song known across China.If you ask Wang Meng,a famed ... Food can represent the past,mark the places we visited and remind us of the people we met,so each new bite revives warm memories.Xinjiang,a Good Place is a popular song known across China.If you ask Wang Meng,a famed writer who spent many years in the region during the tumultuous 1960s and 70s,Ili in western Xinjiang is the best of the best.Its food is one reason he rates it so highly. 展开更多
关键词 China. XINJIANG ili
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ILIS集成图书馆信息系统及在我馆的应用
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作者 汤竞南 《浙江高校图书情报工作》 1994年第3期51-53,共3页
关键词 iliS 图书馆 计算机 信息系统
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伊犁河三角洲水资源条件变化对景观格局演变的影响 被引量:1
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作者 陈启慧 纪璐 +6 位作者 李琼芳 白浩男 韩幸烨 姚佳 崔罡 周正模 杨坤凡 《水资源保护》 EI CAS CSCD 北大核心 2024年第2期90-99,共10页
在分析1992—2020年伊犁河三角洲水资源条件和定量评估研究期内土地利用变化的基础上,选取景观类型水平和景观水平指数解析景观格局变化特征,采用皮尔逊相关系数分析了水资源条件变化对景观格局指数的影响。结果表明:乌斯热尔玛水文站... 在分析1992—2020年伊犁河三角洲水资源条件和定量评估研究期内土地利用变化的基础上,选取景观类型水平和景观水平指数解析景观格局变化特征,采用皮尔逊相关系数分析了水资源条件变化对景观格局指数的影响。结果表明:乌斯热尔玛水文站年径流总体偏大,巴尔喀什湖年平均水位在2002年发生突变,三角洲水资源补给总体处于增加状态;湿地和稀疏植被面积增大且聚集性增强,裸地向稀疏植被转化且优势度不断下降,林地破碎程度剧烈;景观水平指数在时程上呈阶段性变化,2016年伊犁河三角洲破碎化程度最低,在空间上伊犁河沿岸连通性增强,巴尔喀什湖沿岸景观多样性增加;景观水平指数与巴尔喀什湖年平均水位相关性最高,与乌斯热尔玛水文站年径流量的相关性次之,与伊犁河三角洲年降水量的相关性最低,且景观水平指数对三角洲水资源条件变化存在迟滞响应。 展开更多
关键词 景观格局 水资源 移动窗口法 土地利用 伊犁河三角洲
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基于电磁耦合传感的小口径管道缺陷检测系统研发
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作者 汝改革 曾熠 +3 位作者 高斌 孙鹏 王超 吴昊 《中国测试》 CAS 北大核心 2024年第1期88-99,共12页
石油和天然气管道在全球能源基础设施中发挥着至关重要的作用,管道在线内检测(ILI)技术是检测和评估管道完整性的重要工具,然而,它面临着诸多检测挑战,如不同类型缺陷的检出局限。该文提出一种基于电磁感应和永磁体复合磁化机理的新型IL... 石油和天然气管道在全球能源基础设施中发挥着至关重要的作用,管道在线内检测(ILI)技术是检测和评估管道完整性的重要工具,然而,它面临着诸多检测挑战,如不同类型缺陷的检出局限。该文提出一种基于电磁感应和永磁体复合磁化机理的新型ILI传感内检测系统。首先,提出一种可产生轴向漏磁场和周向均匀交流磁场的新型磁环结构(MRS);其次,通过添加永磁体磁化结构,优化励磁结构配置,增强管壁穿透能力和磁通强度;同时,在保证内检测器在小口径管道内安全通过下,克服单一技术限制,提高对浅表层缺陷和较深埋深缺陷的检测能力。为评估所提出的MRS系统的可行性,开展了管道牵拉测试,RMS与永磁铁励磁结构的最优配置,实现对深度0.81 mm表面浅缺陷和埋深4.1 mm的亚表面缺陷检出;最终,通过有限元仿真和实验以及牵拉测试有效验证了所提方法的检测能力。 展开更多
关键词 ili技术 MRS系统 电磁耦合传感 穿透能力 管道通过能力
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新疆流感监测哨点医院HIS登记ILI实施方案探讨 被引量:5
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作者 刘万里 赵俊 +6 位作者 郜振国 张璇 李方 马合木提 李新兰 马会来 岳锡宏 《疾病预防控制通报》 2017年第1期52-54,共3页
目的根据医院信息系统发展趋势探讨制定医院信息系统(HIS)登记流感样病例(ILI)的实施方案。方法2016年4—10月对新疆17家哨点医院进行横断面调查研究,调查同时邀请各哨点医院流感监测相关人员采用归纳法提出HIS登记ILI实施方案。结果根... 目的根据医院信息系统发展趋势探讨制定医院信息系统(HIS)登记流感样病例(ILI)的实施方案。方法2016年4—10月对新疆17家哨点医院进行横断面调查研究,调查同时邀请各哨点医院流感监测相关人员采用归纳法提出HIS登记ILI实施方案。结果根据流感监测哨点医院HIS中疾病诊断分类是否按照ICD-10编码分类,提出HIS登记ILI的两种实施方案。结论 ILI登记模块纳入HIS后,可替代医务人员准确识别ILI,解决流感监测中最关键的ILI的识别及标识问题,为全国制定HIS系统登记ILI规范提供依据。 展开更多
关键词 流感监测 HIS ili 实施方案
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Loess magnetic properties in the Ili Basin and their correlation with the Chinese Loess Plateau 被引量:25
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作者 NAOTO Ishikawa 《Science China Earth Sciences》 SCIE EI CAS 2010年第3期419-431,共13页
Over the past two decades, magnetoclimatological studies of loess-paleosol sequences in the Chinese Loess Plateau (CLP) have made outstanding achievements, which greatly promote the understanding of East Asian paleomo... Over the past two decades, magnetoclimatological studies of loess-paleosol sequences in the Chinese Loess Plateau (CLP) have made outstanding achievements, which greatly promote the understanding of East Asian paleomonsoon evolution, inland aridification of Asia, and past global climate changes. Loess magnetic properties of the CLP have been well studied. In contrast, loess magnetic properties from outside the CLP in China have not been fully understood. We have little knowledge about the magnetic properties of loess in the Ili Basin, an intermontane depression of the Tianshan (or Tien Shan) Mountains. Here, we present the results of rock magnetic measurements of the Ili loess including mass magnetic susceptibility (χ) and anhysteretic remanent magnetization (ARM), high/low temperature dependence of susceptibility (TDS) and hysteresis, as well as X-ray diffraction (XRD) for mineral analysis. Based on the comparison with loess-paleosol sequences in the CLP (hereafter referred to as the Chinese loess), we discuss the possible magnetic susceptibility enhancement mechanism of the Ili loess. The results show that 1) the total magnetic mineral concentration of the Ili loess is far lower than that of the Chinese loess, though they have similar magnetic mineral compositions. The ferrimagnetic minerals in the Ili loess are magnetite and maghemite, and the antiferromagnetic mineral is hematite; XRD analysis also identifies the presence of ilmenite. The ratio of maghemite is lower in the Ili loess than in the Chinese loess, but the ratios of magnetite and hematite are higher in the Ili loess than in the Chinese loess. 2) The granularity of magnetic minerals in the Ili loess, dominated by pseudo-single domain (PSD) and multi-domain (MD) grains, is generally much coarser than that of the Chinese loess. Ultrafine pedogenically-produced magnetic grains have a very limited contribution to the susceptibility enhancement. Rather, PSD and MD particles of magnetite and maghemite are the main contributors to the enhancement of susceptibility in the Ili loess. 3) The susceptibility enhancement mechanism for the Ili loess is complicated and superimposes both a wind velocity/vigor model (Alaskan or Siberian model) and the in situ ultrafine grain pedogenic model; the former might play an important role in the Ili loess. 4) Magnetic susceptibility enhancements of the Ili loess are related not only to the eolian input of the source area, but also to the local climate, landform, and geological background. Therefore, great care should be taken when reconstructing paleoclimate using magnetic susceptibility data from the Ili loess. 展开更多
关键词 LOESS MAGNETIC property MAGNETIC SUSCEPTIBiliTY the ili BASIN the Chinese LOESS PLATEAU
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伊犁河谷山地土壤养分化学计量比及其影响因素
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作者 杨涵 孙慧兰 +3 位作者 田中平 刘天弋 吴芳 金晓亮 《中山大学学报(自然科学版)(中英文)》 CAS CSCD 北大核心 2024年第3期60-70,共11页
探究干旱区山地生态系统中不同海拔梯度土壤化学计量比及影响因子,对揭示土壤养分状况、维持山地生态系统可持续发展具有重要意义。本文以伊犁河谷南部山地沿海拔梯度建立13个样地,以0~20 cm土壤为研究对象,探究土壤养分化学计量比及其... 探究干旱区山地生态系统中不同海拔梯度土壤化学计量比及影响因子,对揭示土壤养分状况、维持山地生态系统可持续发展具有重要意义。本文以伊犁河谷南部山地沿海拔梯度建立13个样地,以0~20 cm土壤为研究对象,探究土壤养分化学计量比及其影响因素。结果表明:1)土壤酸性随着海拔的升高逐渐增强。土壤有机碳与全氮表现出中高山带含量显著高于低山带,而全磷和全钾则表现为低山带含量较高,中高山带含量较低。2)由于海拔差异,碳氮比表现为中高山带显著高于低山带和高山带;碳磷比表现为中高山带显著高于中低山带;碳钾比表现为中高山带显著高于低山带;氮磷比表现为高山带显著较高,但过渡带与低山带无显著差异;氮钾比表现为高山带显著较高,而中高山带与过渡带无显著差异;不同海拔梯度间磷钾比差异性均不显著。3)土壤理化指标中影响化学计量比的主导因子为土壤有机碳(62.4%)、全磷(15.9%)、全碳(13.7%);环境因子对土壤化学计量比产生影响的主导因子为土壤年均温(27.1%)、植被指数(11.2%)、海拔(12.3%)、大气年均温(3.4%)。研究结果说明,理化指标对土壤化学计量比具有重要影响,并且进一步验证了海拔仍然是影响化学计量比的主导因子,同时揭示了微环境因子对土壤化学计量比的影响不容忽视,为深入研究伊犁河谷山地土壤养分状况提供科学依据。 展开更多
关键词 化学计量比 影响因子 土壤养分 伊犁河谷山地
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基于miR-148a-3p/SMAD2轴探讨当归多糖对高糖诱导RGC凋亡的影响
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作者 王江涛 王艳新 +1 位作者 贾冠美 曹朗 《中国中医眼科杂志》 2024年第7期601-609,共9页
目的探究当归多糖(APS)对高糖诱导视网膜神经节细胞(RGC)凋亡的影响,及其基于微小RNA-148a-3p/Smad家族成员2(miR-148a-3p/SMAD2)轴的作用机制。方法将分别转染miR-148a-3p模拟物(mimics)、miR-148a-3p抑制剂(inhibitor)及其对照品mimic... 目的探究当归多糖(APS)对高糖诱导视网膜神经节细胞(RGC)凋亡的影响,及其基于微小RNA-148a-3p/Smad家族成员2(miR-148a-3p/SMAD2)轴的作用机制。方法将分别转染miR-148a-3p模拟物(mimics)、miR-148a-3p抑制剂(inhibitor)及其对照品mimics-NC、miR-NC的RGC,分为对照组(CG)、模型组(MG)、APS低剂量(APS-L)组、APS高剂量(APS-H)组、APS-H+miR-148a-3p对照品组(APS+miR-NC)、APS-H+miR-148a-3p抑制剂组(miR-148a-3p inhibitor),分别以相应的高糖和APS处理,采用实时荧光定量PCR(qRT-PCR)检测miR-148a-3p和SMAD2 mRNA表达水平,检测细胞活力、凋亡情况和氧化应激指标水平,Western Blot法检测SMAD2蛋白表达水平,双荧光素酶实验检测miR-148a-3p和SMAD2的靶向关系。结果(1)miR-148a-3p/SMAD2表达:APS-L组、APS-H组、APS-H+miR-NC组中miR-148a-3p表达水平均高于MG组(t_(APS-L)=6.564、t_(APS-H)=10.542、t_(APS-H+miR-NC)=9.945,均P=0.000),SMAD2 mRNA表达水平低于MG组(t_(APS-L)=4.147,P=0.004;t_(APS-H)=6.464、t_(APS-H+miR-NC)=6.586,均P=0.000);APS-H+miR-148a-3p inhibitor组miR-148a-3p表达水平低于APS-H+miRNC组(t=7.558,P=0.000),SMAD2 mRNA表达高于APS-H+miR-NC组(t=4.513,P=0.001),差异均有统计学意义。(2)细胞活力和凋亡率:APS-L组、APS-H组、APS-H+miR-NC组细胞活力高于MG组(t_(APS-L)=8.105、t_(APS-H)=11.509、t_(APS-H+miR-NC)=11.996,均P=0.000),细胞凋亡率低于MG组(t_(APS-L)=8.729、t_(APS-H)=15.690、t_(APS-H+miR-NC)=14.709,均P=0.000);APS-H+miR-148a-3p inhibitor组细胞活力低于APS-H+miR-NC组(t=10.212,P=0.000),细胞凋亡率高于APS-H+miR-NC组(t=12.247,P=0.000),差异均有统计学意义。(3)氧化应激:APS-L组、APS-H组、APS-H+miR-NC组乳酸脱氢酶(LDH)和丙二醛(MDA)均低于MG组(LDH:t_(APS-L)=11.257、t_(APS-H)=18.770、t_(APS-H+miR-NC)=18.364,均P=0.000;MDA:t_(APS-L)=11.121、t_(APS-H)=17.139、t_(APS-H+miR-NC)=17.768,均P=0.000),超氧化物歧化酶(SOD)和谷胱甘肽(GSH)均高于MG组(SOD:t_(APS-L)=9.408、t_(APS-H)=14.833、t_(APS-H+miR-NC)=13.240,均P=0.000;GSH:t_(APS-L)=5.616、t_(APS-H)=12.080、t_(APS-H+miR-NC)=12.642,均P=0.000);APS-H+miR-148a-3p inhibitor组LDH和MDA均高于APS-H+miR-NC组(t_(LDH)=15.121、t_(MDA)=14.613,均P=0.000),SOD和GSH均低于APS-H+miR-NC组(tSOD=12.278、tGSH=8.912,均P=0.000),差异均有统计学意义。。(4)凋亡蛋白:APS-L组、APS-H组和APS-H+miR-NC组SMAD2、Bcl-2相关X蛋白(Bax)和半胱天冬酶-3(Caspase-3)表达低于MG组(SMAD2:t_(APS-L)=4.565、t_(APS-H)=8.042、t_(APS-H+miR-NC)=7.390,均P=0.000;Bax:t_(APS-L)=4.916、t_(APS-H)=8.763、t_(APS-H+miR-NC)=8.336,均P=0.000;Caspase-3:t_(APS-L)=4.214、t_(APS-H)=10.201、t_(APS-H+miR-NC)=9.536,均P=0.000),B细胞淋巴瘤-2(Bcl-2)表达高于MG组(t_(APS-L)=3.713,P=0.001;t_(APS-H)=10.108、t_(APS-H+miR-NC)=10.314,均P=0.000);APS-H+miR-148a-3p inhibitor组SMAD2、Bax、Caspase-3表达均高于APS-H+miR-NC组(t_(SMAD2)=5.651、t_(Bax)=6.840、t_(Caspase-3)=8.205,均P=0.000),Bcl-2表达低于APS-H+miR-NC组(t=9.283,P=0.000),差异均有统计学意义。(5)靶向关系:miR-148a-3p与SMAD2的3'非翻译区存在结合位点。miR-148a-3p mimics和野生型SMAD2共转染组荧光素酶活性低于mimics-NC和野生型SMAD2共转染组,差异有统计学意义(t=12.781,P=0.000)。结论当归多糖可能通过上调miR-148a-3p、下调SMAD2,改善高糖诱导的RGC凋亡和氧化应激损伤。 展开更多
关键词 当归多糖 视网膜神经节细胞 微小RNA-148a-3p SMAD家族成员2
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2000—2022年伊犁河流域植被时空变化特征
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作者 李雅倩 杨建华 +1 位作者 夏皓斌 武建军 《干旱区地理》 CSCD 北大核心 2024年第5期741-752,共12页
伊犁河流域横跨中哈两国,生态环境脆弱,深化对全流域植被变化的认识对于该地区生态可持续发展具有重要意义。基于MODIS的增强型植被指数(EVI)数据,深入研究了2000—2022年整个伊犁河流域植被的时空变化特征,并对比了中国境内外伊犁河流... 伊犁河流域横跨中哈两国,生态环境脆弱,深化对全流域植被变化的认识对于该地区生态可持续发展具有重要意义。基于MODIS的增强型植被指数(EVI)数据,深入研究了2000—2022年整个伊犁河流域植被的时空变化特征,并对比了中国境内外伊犁河流域、不同植被类型、不同高程间植被变化的差异。结果表明:(1)2000年以来伊犁河流域植被总体呈现改善趋势,尤其是哈萨克斯坦境内的植被,然而中国境内植被有退化趋势。植被退化区域的高程集中在1000~3000 m之间;草地和耕地以改善为主,林地则相反。(2)过去20 a间,伊犁河流域植被总体波动较小,但中国境内流域植被的波动性较大。与林地和耕地相比,草地的波动性更大。高程在2500~3000 m区域内的植被波动小。(3)未来伊犁河流域植被状况以持续改善为主,持续改善面积约占全流域面积的52%。草地持续改善的面积占比高于耕地和林地。高程低于1000 m和高于3000 m区域的植被以持续改善为主。研究结果将有助于加深对伊犁河流域植被变化特征的理解,为流域生态环境保护提供科学参考。 展开更多
关键词 MODIS EVI 变化趋势 持续性 伊犁河流域
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牧村景观及其再造——新疆伊犁河流域琼库什台村的个案
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作者 罗意 郭志静 《湖北民族大学学报(哲学社会科学版)》 CSSCI 北大核心 2024年第1期45-55,共11页
新疆伊犁河流域的琼库什台村是一个传统牧村,也是一个中国历史文化名村。该牧村的传统景观由聚落空间、生产空间、生活空间构成并以牧道空间连接为一体,彰显了“人·畜·草”和谐共生的生态智慧。近年来,旅游发展深刻改变了牧... 新疆伊犁河流域的琼库什台村是一个传统牧村,也是一个中国历史文化名村。该牧村的传统景观由聚落空间、生产空间、生活空间构成并以牧道空间连接为一体,彰显了“人·畜·草”和谐共生的生态智慧。近年来,旅游发展深刻改变了牧村的聚落空间、生产空间与生活空间,创造了新的文化空间,传统生态智慧被创造性转化后融入旅游新业态之中,进而从整体上再造了牧村景观。生态人类学要积极介入景观研究,利用传统景观分析识别和把握地方人群的“生态智慧”,通过景观再造考察理解并阐释人与自然和谐共生的中国式现代化。 展开更多
关键词 景观人类学 牧村景观 生态智慧 伊犁河流域
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乾隆年间伊犁户屯问题再探
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作者 衡宗亮 张艾云 《农业考古》 北大核心 2024年第1期63-69,共7页
户屯是清代伊犁农业开发中的特殊类型,根据满文档案可知,其创办时间更可能始于乾隆二十五年。户屯构造,主要包括了商民、客民、为民遣犯和绿营眷兵分户子弟四类。户屯最早依附于兵屯,其管理实现了从理事同知向抚民同知的转变。
关键词 乾隆年间 伊犁 户屯 农业开发
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