Objective: To relate cardiovascular risk factor knowledge to lifestyle. Methods: In this cross-sectional study, food consumption and lifestyle characteristics were recorded using mailed questionnaires. The dietary pat...Objective: To relate cardiovascular risk factor knowledge to lifestyle. Methods: In this cross-sectional study, food consumption and lifestyle characteristics were recorded using mailed questionnaires. The dietary pattern was described using the Mediterranean Diet Score (MDS). An open ended questionnaire without predefined choices or answers was used to capture cardiovascular knowledge. Results: Lack of physical activity, smoking and eating too much fat were the 3 most cited potential cardiovascular risk factors, while being overweight, eating too much salt and a low consumption of fruits and vegetables were the least cited risk factors. Age, Body Mass Index, physical activity, smoking, income and dietary habits were not consistently associated with knowledge of risk factors. A low socioeconomic position as measured by the indicator education was associated with a lower knowledge of established and modifiable cardiovascular risk factors. Conclusions: Risk factor knowledge, an essential step in prevention of CVD, is not systematically associated with a healthier lifestyle. The findings of this study confirm that there is a gap between risk factor knowledge and lifestyle.展开更多
Background: Evidence on the relations of the American Heart Association’s ideal cardiovascular health (ICH) with mortality in Asians is sparse, and the interaction between behavioral and medical metrics remained uncl...Background: Evidence on the relations of the American Heart Association’s ideal cardiovascular health (ICH) with mortality in Asians is sparse, and the interaction between behavioral and medical metrics remained unclear. We aimed to fill the gaps. Methods: A total of 198,164 participants without cancer and cardiovascular disease (CVD) were included from the China Kadoorie Biobank study (2004-2018), Dongfeng-Tongji cohort (2008-2018), and Kailuan study (2006-2019). Four behaviors (i.e., smoking, physical activity, diet, body mass index) and three medical factors (i.e., blood pressure, blood glucose, and blood lipid) were classified into poor, intermediate, and ideal levels (0, 1, and 2 points), which constituted 8-point behavioral, 6-point medical, and 14-point ICH scores. Results of Cox regression from three cohorts were pooled using random-effects models of meta-analysis. Results: During about 2 million person-years, 20,176 deaths were recorded. After controlling for demographic characteristics and alcohol drinking, hazard ratios (95% confidence intervals) comparing ICH scores of 10-14 vs. 0-6 were 0.52 (0.41-0.67), 0.44 (0.37-0.53), 0.54 (0.45-0.66), and 0.86 (0.64-1.14) for all-cause, CVD, respiratory, and cancer mortality. A higher behavioral or medical score was independently associated with lower all-cause and CVD mortality among the total population and populations with different levels of behavioral or medical health equally, and no interaction was observed. Conclusions: ICH was associated with lower all-cause, CVD, and respiratory mortality among Chinese adults. Both behavioral and medical health should be improved to prevent premature deaths.展开更多
South Asians(SA)are at higher cardiovascular risk than other ethnic groups,and SA kidney transplant recipients(SA KTR)are no exception.SA KTR experience increased major adverse cardiovascular events both early and lat...South Asians(SA)are at higher cardiovascular risk than other ethnic groups,and SA kidney transplant recipients(SA KTR)are no exception.SA KTR experience increased major adverse cardiovascular events both early and late posttransplantation.Cardiovascular risk management should therefore begin well before transplantation.SA candidates may require aggressive screening for pretransplant cardiovascular disease(CVD)due to their ethnicity and comorbidities.Recording SA ethnicity during the pre-transplant evaluation may enable programs to better assess cardiovascular risk,thus allowing for earlier targeted periand post-transplant intervention to improve cardiovascular outcomes.Diabetes remains the most prominent post-transplant cardiovascular risk factor in SA KTR.Diabetes also clusters with other metabolic syndrome components including lower high-density lipoprotein cholesterol,higher triglycerides,hypertension,and central obesity in this population.Dyslipidemia,metabolic syndrome,and obesity are all significant CVD risk factors in SA KTR,and contribute to increased insulin resistance.Novel biomarkers such as adiponectin,apolipoprotein B,and lipoprotein(a)may be especially important to study in SA KTR.Focused interventions to improve health behaviors involving diet and exercise may especially benefit SA KTR.However,there are few interventional clinical trials specific to the SA population,and none are specific to SA KTR.In all cases,understanding the nuances of managing SA KTR as a distinct post-transplant group,while still screening for and managing each CVD risk factor individually in all patients may help improve the long-term success of all kidney transplant programs catering to multi-ethnic populations.展开更多
文摘Objective: To relate cardiovascular risk factor knowledge to lifestyle. Methods: In this cross-sectional study, food consumption and lifestyle characteristics were recorded using mailed questionnaires. The dietary pattern was described using the Mediterranean Diet Score (MDS). An open ended questionnaire without predefined choices or answers was used to capture cardiovascular knowledge. Results: Lack of physical activity, smoking and eating too much fat were the 3 most cited potential cardiovascular risk factors, while being overweight, eating too much salt and a low consumption of fruits and vegetables were the least cited risk factors. Age, Body Mass Index, physical activity, smoking, income and dietary habits were not consistently associated with knowledge of risk factors. A low socioeconomic position as measured by the indicator education was associated with a lower knowledge of established and modifiable cardiovascular risk factors. Conclusions: Risk factor knowledge, an essential step in prevention of CVD, is not systematically associated with a healthier lifestyle. The findings of this study confirm that there is a gap between risk factor knowledge and lifestyle.
基金supported by grants from the National Nature Science Foundation of China(Nos.81930124 and 82021005)The Dongfeng-Tongji cohort was supported by the National Key Research and Development Program of China(Nos.2016YFC0900801 and 2017YFC0907504)+2 种基金The China Kadoorie Biobank study was funded by the National Natural Science Foundation of China(Nos.82192901,82192900,and 81390540)the National Key Research and Development Program of China(No.2016YFC0900500)and the Chinese Ministry of Science and Technology(No.2011BAI09B01).
文摘Background: Evidence on the relations of the American Heart Association’s ideal cardiovascular health (ICH) with mortality in Asians is sparse, and the interaction between behavioral and medical metrics remained unclear. We aimed to fill the gaps. Methods: A total of 198,164 participants without cancer and cardiovascular disease (CVD) were included from the China Kadoorie Biobank study (2004-2018), Dongfeng-Tongji cohort (2008-2018), and Kailuan study (2006-2019). Four behaviors (i.e., smoking, physical activity, diet, body mass index) and three medical factors (i.e., blood pressure, blood glucose, and blood lipid) were classified into poor, intermediate, and ideal levels (0, 1, and 2 points), which constituted 8-point behavioral, 6-point medical, and 14-point ICH scores. Results of Cox regression from three cohorts were pooled using random-effects models of meta-analysis. Results: During about 2 million person-years, 20,176 deaths were recorded. After controlling for demographic characteristics and alcohol drinking, hazard ratios (95% confidence intervals) comparing ICH scores of 10-14 vs. 0-6 were 0.52 (0.41-0.67), 0.44 (0.37-0.53), 0.54 (0.45-0.66), and 0.86 (0.64-1.14) for all-cause, CVD, respiratory, and cancer mortality. A higher behavioral or medical score was independently associated with lower all-cause and CVD mortality among the total population and populations with different levels of behavioral or medical health equally, and no interaction was observed. Conclusions: ICH was associated with lower all-cause, CVD, and respiratory mortality among Chinese adults. Both behavioral and medical health should be improved to prevent premature deaths.
文摘South Asians(SA)are at higher cardiovascular risk than other ethnic groups,and SA kidney transplant recipients(SA KTR)are no exception.SA KTR experience increased major adverse cardiovascular events both early and late posttransplantation.Cardiovascular risk management should therefore begin well before transplantation.SA candidates may require aggressive screening for pretransplant cardiovascular disease(CVD)due to their ethnicity and comorbidities.Recording SA ethnicity during the pre-transplant evaluation may enable programs to better assess cardiovascular risk,thus allowing for earlier targeted periand post-transplant intervention to improve cardiovascular outcomes.Diabetes remains the most prominent post-transplant cardiovascular risk factor in SA KTR.Diabetes also clusters with other metabolic syndrome components including lower high-density lipoprotein cholesterol,higher triglycerides,hypertension,and central obesity in this population.Dyslipidemia,metabolic syndrome,and obesity are all significant CVD risk factors in SA KTR,and contribute to increased insulin resistance.Novel biomarkers such as adiponectin,apolipoprotein B,and lipoprotein(a)may be especially important to study in SA KTR.Focused interventions to improve health behaviors involving diet and exercise may especially benefit SA KTR.However,there are few interventional clinical trials specific to the SA population,and none are specific to SA KTR.In all cases,understanding the nuances of managing SA KTR as a distinct post-transplant group,while still screening for and managing each CVD risk factor individually in all patients may help improve the long-term success of all kidney transplant programs catering to multi-ethnic populations.
文摘目的综合评价世界人群理想心血管健康行为和因素的流行趋势,为心血管疾病的预防提供基础参考资料。方法系统检索Pub Med、Springer、Elsevier、EMBase、SSCI、中国生物医学文献服务系统（CBM）、中国期刊全文数据库（CJFD）、万方数据库、中国优秀硕士学位论文全文数据库（CMFD）及中国重要会议论文全文数据库（CPFD）中关于理想心血管健康行为和因素、相关心血管事件的文献。检索时间为2010年1月—2014年3月。采用Rev Man 3.1.0软件对符合纳入及排除标准的文献采用随机效应模型进行Meta分析。结果共纳入文献10篇,总样本量为519 052人。世界人群具有7项理想心血管健康行为和因素的人数发生率为0.47%〔95%CI（0.22%,1.03%）〕,具有5~7项理想心血管健康行为和因素的人数发生率为16.26%〔95%CI（11.18%,23.05%）〕。亚组分析显示,女性人群具有5~7项理想心血管健康行为和因素的人数发生率为23.25%〔95%CI（19.34%,27.69%）〕,男性人群具有5~7项理想心血管健康行为和因素的人数发生率为8.08%〔95%CI（4.56%,13.92%）〕,不同性别间理想心血管健康行为和因素的人数发生率比较,差异有统计学意义（Z=-2.67,P=0.008）。结论世界人群理想心血管健康行为和因素的发生率较低,女性优于男性。建议关注并采取积极干预措施,提高人群理想心血管健康水平。
