Recent studies have found that although tinnitus originates from the cochlea,its root lies in the plasticity of the auditory center.In other words,the peripheral auditory system damage causes abnormal excitement and e...Recent studies have found that although tinnitus originates from the cochlea,its root lies in the plasticity of the auditory center.In other words,the peripheral auditory system damage causes abnormal excitement and even functional reorganization of the brain stem and cerebral cortex,finally leading to tinnitus progresses and persists in the center.The mechanism of"central plasticity"is related to the physiological characteristics of related brain regions,the characteristics of electrophysiological changes,the changes of central neurotransmitters,and psychological factors.It is speculated that the possible mechanisms of the acupuncture treatment of tinnitus are as follows:1.Acupuncture can alter the level of neurotransmitters 5-HT and GABA in nerve center,that is,GABA increases and 5-HT decreases after acupuncture;2.Acupuncture changes the wrong central pattern of the cerebral cortex caused by tinnitus through strong stimulation,and aids the cerebral cortex adapt to the changes of the internal and external environment to produce benign functional reorganization,in order to treat tinnitus;3.External stimulation of acupuncture can accelerate the contraction of muscle vessels around the ears,accelerate blood circulation and metabolism,and improve the blood supply of the auditory system,thus improving tinnitus.4.Acupuncture can improve or even cure tinnitus by stimulating the acupoint-nerve pathway around the ear,regulating unbalanced neurotransmitters,inhibiting abnormal nerve discharge,correcting wrong auditory pathway patterns,and establishing new auditory pathway nerve conduction patterns.展开更多
基金supported by the TCM Evidence-based capacity Building project-evidence-based research on acupuncture and moxibustion treatment of dominant diseases(2019XZZX-ZJ010)National Key Research and development Program(2017YFC1703600,2017YFC1703603)Shaanxi Provincial Administration of Traditional Chinese Medicine:Shaanxi Electroacupuncture School Inheritance Studio(construction)project(2018).
文摘Recent studies have found that although tinnitus originates from the cochlea,its root lies in the plasticity of the auditory center.In other words,the peripheral auditory system damage causes abnormal excitement and even functional reorganization of the brain stem and cerebral cortex,finally leading to tinnitus progresses and persists in the center.The mechanism of"central plasticity"is related to the physiological characteristics of related brain regions,the characteristics of electrophysiological changes,the changes of central neurotransmitters,and psychological factors.It is speculated that the possible mechanisms of the acupuncture treatment of tinnitus are as follows:1.Acupuncture can alter the level of neurotransmitters 5-HT and GABA in nerve center,that is,GABA increases and 5-HT decreases after acupuncture;2.Acupuncture changes the wrong central pattern of the cerebral cortex caused by tinnitus through strong stimulation,and aids the cerebral cortex adapt to the changes of the internal and external environment to produce benign functional reorganization,in order to treat tinnitus;3.External stimulation of acupuncture can accelerate the contraction of muscle vessels around the ears,accelerate blood circulation and metabolism,and improve the blood supply of the auditory system,thus improving tinnitus.4.Acupuncture can improve or even cure tinnitus by stimulating the acupoint-nerve pathway around the ear,regulating unbalanced neurotransmitters,inhibiting abnormal nerve discharge,correcting wrong auditory pathway patterns,and establishing new auditory pathway nerve conduction patterns.
