A modified OMP method for multi-orbit three dimensional ISAR imaging of the space target

The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is proposed based on mutliorbit observation data and an improved orthogonal matching pursuit(OMP)algorithm.Firstly,the 3D scattered field data is converted into a set of 2D matrix by stacking slices of the 3D data along the elevation direction dimension.Then,an improved OMP algorithm is applied to recover the space target's amplitude information via the 2D matrix data.Finally,scattering centers can be reconstructed with specific three dimensional locations.Numerical simulations are provided to demonstrate the effectiveness and superiority of the proposed 3D imaging method.

Four-dimensional flow magnetic resonance imaging incirrhosis

Since its introduction in the 1970’s,magnetic resonance imaging(MRI)has become a standard imaging modality.With its broad and standardized application,it is firmly established in the clinical routine and an essential element in cardiovascular and abdominal imaging.In addition to sonography and computer tomography,MRI is a valuable tool for diagnosing cardiovascular and abdominal diseases,for determining disease severity,and for assessing therapeutic success.MRI techniques have improved over the last few decades,revealing not just morphologic information,but functional information about perfusion,diffusion and hemodynamics as well.Four-dimensional(4D)flow MRI,a time-resolved phase contrast-MRI with three-dimensional(3D)anatomic coverage and velocity encoding along all three flow directions has been used to comprehensively assess complex cardiovascular hemodynamics in multiple regions of the body.The technique enables visualization of 3D blood flow patterns and retrospective quantification of blood flow parameters in a region of interest.Over the last few years,4D flow MRI has been increasingly performed in the abdominal region.By applying different acceleration techniques,taking 4D flow MRI measurements has dropped to a reasonable scanning time of 8 to 12 min.These new developments have encouraged a growing number of patient studies in the literature validating the technique’s potential for enhanced evaluation of blood flow parameters within the liver’s complex vascular system.The purpose of this review article is to broaden our understanding of 4D flow MRI for the assessment of liver hemodynamics by providing insights into acquisition,data analysis,visualization and quantification.Furthermore,in this article we highlight its development,focussing on the clinical application of the technique.

Continuous imaging space in three-dimensional integral imaging

We report an integral imaging method with continuous imaging space. This method simultaneously reconstructs real and virtual images in the virtual mode, with a minimum gap that separates the entire imaging space into real and virtual space. Experimental results show that the gap is reduced to 45% of that in a conventional integral imaging system with the same parameters.

Three-dimensional imaging identified the accessory bile duct in a patient with cholangiocarcinoma

The development of diagnostic imaging technology, such as multidetector computed tomography(MDCT) and magnetic resonance cholangiopancreatography(MRCP), has made it possible to obtain detailed images of the bile duct. Recent reports have indicated that a 3-dimensional(3D) reconstructed imaging system would be useful for understanding the liver anatomy before surgery. We have investigated a novel method that fuses MDCT and MRCP images. This novel system easily made it possible to detect the anatomical relationship between the vessels and bile duct in the portal hepatis. In this report, we describe a very rare case of extrahepatic cholangiocarcinoma associated with an accessory bile duct from the caudate lobe connecting with the intrapancreatic bile duct. We were unable to preoperatively detect this accessory bile duct using MDCT and MRCP. However, prior to the second operation, we were able to clearly visualise the injured accessory bile duct using our novel 3D imaging modality. In thisreport, we suggest that this imaging technique can be considered a novel and useful modality for understanding the anatomy of the portal hepatis, including the hilar bile duct.

3-Dimensional Irradiance Imaging with a Single Camera System

The focusing tomography is presented to reconstruct 3 dimensional irradiance distribution. A 3 dimensional luminous body could be considered as the combination of many 2 dimensional parallel luminous sections. Focus on these discrete sections respectively by a single camera, a group of images would be captured to form governing equations of irradiance. After inversion procedure, the irradiance distribution of different sections could be decoded. In this experimentation two lightbulbs are used to simulate two luminous sections. Reasonable results demonstrate that this technique could be a useful method in irradiance reconstruction after further development.

Application of Three-Dimensional Magnetic Resonance Imaging in the Diagnosis of Perianal Abscess

Perianal abscess is a common disease in anorectal surgery. If the diagnosis is not clear and the cure is thoroughly cleared, the recurrence and spread of anal fistula will cause life-long pain. Objective: To investigate the application of 3.0T MRI 3D CUBE T2WI lipid suppression sequence in the diagnosis of perianal abscess. Methods: Thirty-six patients with perianal abscess confirmed by operation were examined with 2D T2WI and 3D CUBE T2WI lipid suppression sequences before operation. Two imaging techniques were evaluated to show the types of perianal abscess, the number of abscesses, the number of internal orifices of abscess, and the number of fistula branches with anal fistula in abscess. Results: Among 36 cases of perianal abscess, there were 5 cases of anal subcutaneous abscess, 12 cases of ischiorectal space abscess (8 cases complicated with anal fistula), 6 cases of posterior anal space abscess, 5 cases of anal sphincter abscess (3 cases complicated with anal fistula), 2 cases of high intermuscular abscess, 2 cases of rectal submucosal abscess, 3 cases of complex abscess (3 cases complicated with anal fistula), 1 case of misdiagnosis, 2D T2WI lipid suppression sequence and 3D CUBE T2WI suppression. The accuracy of lipid sequence abscess typing was 80.6% (29/36) and 88.9% (32/36), respectively, with no significant difference (P > 0.05). Thirty-six patients were surgically diagnosed as having 32 internal orifices, 68.8% (22/32) and 93.8% (30/32) of 2D T2WI and 3D CUBE T2WI lipid-suppressing sequences, respectively, with significant difference (P Conclusion: 3D CUBE T2WI lipid suppression sequence is superior to 2D T2WI lipid suppression sequence in the classification of perianal abscess, the number of internal orifices of abscess and the number of fistula branches of abscess complicated with anal fistula. It can also determine the number of internal orifices of abscess complicated with anal fistula, the number of fistula branches, the shape of primary and branch fistula and the relationship among pelvic floor muscle tissues. It can provide more accurate images for preoperative and intraoperative clinical surgery.

Prenatal Diagnosis of Sirenomelia by Two-Dimensional and Three-Dimensional Skeletal Imaging Ultrasound

Summary： This study sought to evaluate the contribution of two-dimensional ultrasound （2D-US） and three-dimensional skeletal imaging ultrasound （3D-SUIS） in the prenatal diagnosis of sirenomelia. Be- tween September 2010 and April 2014, a prospective study was conducted in a single referral center using 3D-SU1S performed after 2D-US in 10 cases of sirenomelia. Diagnostic accuracy and detailed findings were compared with postnatal three-dimensional helical computed tomography （3D-HCT）, radiological findings and autopsy. Pregnancy was terminated in all 10 sirenomelia cases, including 9 singletons and I conjoined twin pregnancy, for a total of 5 males and 5 females. These cases of sirenomelia were deter- mined by autopsy and/or chromosomal examination. Initial 2D-US showed that there were 10 cases of oligohydranmios, bilateral renal agenesis, bladder agenesis, single umbilical artery, fusion of the lower limbs and spinal abnormalities; 8 cases of dipus or monopus; 2 cases of apus; and 8 cases of cardiac abnormalities. Subsequent 3D-SUIS showed that there were 9 cases of scoliosis, l0 cases of sacrococ- cygeal vertebra dysplasia, 3 cases of hemivertebra, 1 case of vertebral fusion, 3 cases of spina bifida, and 5 cases of rib abnormalities. 3D-SUIS identified significantly more skeletal abnormalities than did 2D-US, and its accuracy was 79.5% （70/88） compared with 3D-HCT and radiography. 3D-SUIS seems to be a useful complementary method to 2D-US and may improve the accuracy of identifying prenatal skeletal abnormalities related to sirenomelia.

Real-time Three-Dimensional Color Doppler Flow Imaging： An Improved Technique for Quantitative Analysis of Aortic Regurgitation

The recently introduced real-time three-dimensional color Doppler flow imaging （RT-3D CDFI） technique provides a quick and accurate calculation of regurgitant jet volume （RJV） and fraction. In order to evaluate RT-3D CDFI in the noninvasive assessment of aortic RJV and regurgitant jet fraction （RJF） in patients with isolated aortic regurgitation, real-time three-dimensional echocardiographic studies were performed on 23 patients with isolated aortic regurgitation to obtain LV end-diastolic volumes （LVEDV）, end-systolic volumes （LVESV） and RJV, and then RJF could be calculated. The regurgitant volume （RV） and regurgitant fraction （RF） calculated by two-dimensional pulsed Doppler （2D-PD） method served as reference values. The results showed that aortic RJV measured by the RT-3D CDFI method showed a good correlation with the 2D-PD measurements （r= 0.93, Y=0.89X＋ 3.9, SEE= 8.6 mL, P〈0.001 ）; the mean （SD） difference between the two methods was - 1.5 （9.8） mL. % RJF estimated by the RT-3D CDFI method was also correlated well with the values obtained by the 2D-PD method （r=0.88, Y=0.71X＋ 14.8, SEE= 6.4 %, P〈0. 001）; the mean （SD） difference between the two methods was -1.2 （7.9） %. It was suggested that the newly developed RT-3D CDFI technique was feasible in the majority of patients. In patients with eccentric aortic regurgitation, this new modality provides additional information to that obtained from the two-dimensional examination, which overcomes the inherent limitations of two-dimensional echocardiography by depicting the full extent of the jet trajectory. In addition, the RT-3D CDFI method is quick and accurate in calculating RJV and RJF.

Evaluation of Airway Obstruction at Soft Palate Level in Male Patients with Obstructive Sleep Apnea/Hypopnea Syndrome:Dynamic 3-Dimensional CT Imaging of Upper Airway

This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome（OSAHS） by using dynamic 3-Dimensional（3-D） CT imaging.A total of 41 male patients who presented with 2 of the following symptoms,i.e.,daytime sleepiness and fatigue,frequent snoring,and apnea with witness,were diagnosed as having OSAHS.They underwent full-night polysomnography and then dynamic 3-D CT imaging of the upper airway during quiet breathing and in Muller＇s maneuver.The soft palate length（SPL）,the minimal cross-sectional area of the retropalatal region（mXSA-RP）,and the vertical distance from the hard palate to the upper posterior part of the hyoid（hhL） were compared between the two breathing states.These parameters,together with hard palate length（HPL）,were also compared between mild/moderate and severe OSAHS groups.Association of these parameters with the severity of OSAHS [as reflected by apnea hypopnea index（AHI） and the lowest saturation of blood oxygen（LSaO2）] was examined.The results showed that 31 patients had severe OSAHS,and 10 mild/moderate OSAHS.All the patients had airway obstruction at soft palate level.mXSA-RP was significantly decreased and SPL remarkably increased during Muller＇s maneuver as compared with the quiet breathing state.There were no significant differences in these airway parameters（except the position of the hyoid bone） between severe and mild/moderate OSAHS groups.And no significant correlation between these airway parameters and the severity of OSAHS was found.The position of hyoid was lower in the severe OSAHS group than in the mild/moderate OSAHS group.The patients in group with body mass index（BMI）≥26 had higher collapse ratio of mXSA-RP,greater neck circumference and smaller mXSA-RP in the Muller＇s maneuver than those in group with BMI26（P0.05 for all）.It was concluded that dynamic 3-D CT imaging could dynamically show the upper airway changes at soft palate level in OSAHS patients.All the OSAHS patients had airway obstruction of various degrees at soft palate level.But no correlation was observed between the airway change at soft palate level and the severity of OSAHS.The patients in group with BMI≥26 were more likely to develop airway obstruction at soft palate level than those with BMI26.

Magnetic resonance imaging-three-dimensional printing technology fabricates customized scaffolds for brain tissue engineering

Conventional fabrication methods lack the ability to control both macro- and micro-structures of generated scaffolds. Three-dimensional printing is a solid free-form fabrication method that provides novel ways to create customized scaffolds with high precision and accuracy. In this study, an electrically controlled cortical impactor was used to induce randomized brain tissue defects. The overall shape of scaffolds was designed using rat-specific anatomical data obtained from magnetic resonance imaging, and the internal structure was created by computer- aided design. As the result of limitations arising from insufficient resolution of the manufacturing process, we magnified the size of the cavity model prototype five-fold to successfully fabricate customized collagen-chitosan scaffolds using three-dimensional printing. Results demonstrated that scaffolds have three-dimensional porous structures, high porosity, highly specific surface areas, pore connectivity and good internal characteristics. Neural stem cells co-cultured with scaffolds showed good viability, indicating good biocompatibility and biodegradability. This technique may be a promising new strategy for regenerating complex damaged brain tissues, and helps pave the way toward personalized medicine.

Visibility enhancement in two-dimensional lensless ghost imaging with true thermal light

We report an experimental demonstration of two-dimensional（2D） lensless ghost imaging with true thermal light. An electrodeless discharge lamp with a higher light intensity than the hollow cathode lamp used before is employed as a light source. The main problem encountered by the 2D lensless ghost imaging with true thermal light is that its coherence time is much shorter than the resolution time of the detection system. To overcome this difficulty we derive a method based on the relationship between the true and measured values of the second-order optical intensity correlation, by which means the visibility of the ghost image can be dramatically enhanced. This method would also be suitable for ghost imaging with natural sunlight.

A rapid micro-magnetic resonance imaging scanning for three-dimensional reconstruction of peripheral nerve fascicles

The most common methods for three-dimensional reconstruction of peripheral nerve fascicles include histological and radiology techniques. Histological techniques have many drawbacks including an enormous manual workload and poor image registration. Micro-magnetic resonance imaging（Micro-MRI）, an emerging radiology technique, has been used to report results in the brain, liver and tumor tissues. However, micro-MRI usage for obtaining intraneural structures has not been reported. The aim of this study was to present a new imaging method for three-dimensional reconstruction of peripheral nerve fascicles by ~1T micro-MRI. Freshly harvested sciatic nerve samples from an amputated limb were divided into four groups. Two different scanning conditions（Mannerist Solution/GD-DTPA contrast agent, distilled water） were selected, and both T1 and T2 phases programmed for each scanning condition. Three clinical surgeons evaluated the quality of the images via a standardized scale. Moreover, to analyze deformation of the two-dimensional image, the nerve diameter and total area of the micro-MRI images were compared after hematoxylin-eosin staining. The results show that rapid micro-MRI imaging method can be used for three-dimensional reconstruction of the fascicle structure. Nerve sample immersed in contrast agent（Mannerist Solution/GD-DTPA） and scanned in the T1 phase was the best. Moreover, the nerve sample was scanned freshly and can be recycled for other procedures. MRI images show better stability and smaller deformation compared with histological images. In conclusion, micro-MRI provides a feasible and rapid method for three-dimensional reconstruction of peripheral nerve fascicles, which can clearly show the internal structure of the peripheral nerve.

Validation of a novel imaging approach using multi-slice CT and cone-beam CT to follow-up on condylar remodeling after bimaxillary surgery

The main goal of this study was to introduce a novel three-dimensional procedure to objectively quantify both inner and outer condylar remodelling on preoperative multi-slice computed tomography （MSCT） and postoperative cone-beam computed tomography （CBCT） images. Second, the reliability and accuracy of this condylar volume quantification method was assessed. The mandibles of 20 patients （11 female and 9 male） who underwent bimaxillary surgery were semi-automatically extracted from MSCT/CBCT scans and rendered in 3D. The resulting condyles were spatially matched by using an anatomical landmark-based registration procedure. A standardized sphere was created around each condyle, and the condylar bone volume within this selected region of interest was automatically calculated. To investigate the reproducibility of the method, inter- and intra-observer reliability was calculated for assessments made by two experienced radiologists twice five months apart in a set of ten randomly selected patients. To test the accuracy of the bone segmentation, the inner and outer bone structures of one dry mandible, scanned according to the clinical set-up, were compared with the gold standard, micro-CT. Thirty-eight condyles showed a significant （P〈O.05） mean bone volume decrease of 26.4%_ 11.4% （502.9 mm3＋ 268.1 mm3）. No significant effects of side, sex or age were found. Good to excellent （ICC〉 0.6） intra- and inter-observer reliability was observed for both MSCT and CBCT. Moreover, the bone segmentation accuracy was less than one voxel （0.4 mm） for MSCT （0.3 mm __. 0.2 mm） and CBCT （0.4 mm _ 0.3 mm）, thus indicating the clinical potential of this method for objective follow-up in pathological condylar resorption.

Value of CA19-9, CA125 and CEA combined magnetic resonance imaging in the diagnosis of pancreatic cancer

Objective:To study the value of CA19-9, CA125 and CEA combined magnetic resonance imaging (MRI) in the diagnosis of pancreatic cancer, and to provide a reference for clinical diagnosis and treatment.Methods:A total of 110 cases of pancreatic cancer admitted to our hospital from November 2015 to November 2017 were selected as the observation group, and another 80 normal pancreas organizers who participated in the physical examination in the same period were selected as the control group. The change of magnetic resonance scanning parameters and serum CA19-9, CA125 and CEA detection were compared between the two groups of subjects at the same time, contrast scan and serum magnetic resonance detection of CA19-9, CA125 and CEA positive rate, and to evaluate the four alone and in combination with the diagnosis of pancreatic cancer specificity, sensitivity, negative predictive value and positive predictive value.Results:The T1WI of the observation group was low or slightly low signal, T2WI was slightly high signal, and the tumor of fat suppression sequence was low signal, which was in line with the typical characteristics of pancreatic cancer. The serum levels of CA19-9, CA125 and CEA in the observation group were significantly higher than those in the control group, and the difference was statistically significant. Compared with the two groups, the positive rates of MRI and serum CA19-9, CA125 and CEA in the observation group were higher than those in the control group, and the difference was statistically significant. The sensitivity and accuracy of MRI scan combined with three serological markers were higher than those of single detection. The specificity was between four.Conclusion: CA19-9, CA125 and CEA combined magnetic resonance imaging (MRI) have good sensitivity and accuracy in diagnosis of pancreatic cancer, but their specificity is common, which should be used for reference.

A super-high angular resolution principle for coded-mask X-ray imaging beyond the diffraction limit of a single pinhole

High angular resolution X-ray imaging is always useful in astrophysics and solar physics. In principle, it can be performed by using coded-mask imaging with a very long mask-detector distance. Previously, the diffraction-interference effect was thought to degrade coded-mask imaging performance dramatically at the low energy end with its very long mask-detector distance. The diffraction-interference effect is described with numerical calculations, and the diffraction-interference cross correlation reconstruction method （DICC） is developed in order to overcome the imaging performance degradation. Based on the DICC, a super-high angular resolution principle （SHARP） for coded-mask X-ray imaging is proposed. The feasibility of coded mask imaging beyond the diffraction limit of a single pinhole is demonstrated with simulations. With the specification that the mask element size is 50 × 50 μm^2 and the mask-detector distance is 50 m, the achieved angular resolution is 0.32arcsec above about 10keV and 0.36arcsec at 1.24keV （λ = 1 nm）, where diffraction cannot be neglected. The on-axis source location accuracy is better than 0.02 arcsec. Potential applications for solar observations and wide-field X-ray monitors are also briefly discussed.

An active coronagraph using a liquid crystal array for exoplanet imaging:principle and testing

High-contrast imaging coronagraphs, used for the detection of exoplanets, have always adopted passive coronagraph optical components. It is therefore impossible to actively optimize the coronagraphs to achieve their best performance. To solve this problem, we propose a novel high-contrast imaging coronagraph which combines a liquid crystal array （LCA） for active pupil apodization and a deformable mirror （DM） for phase correction. The LCA we use is an amplitude-only spatial light mod- ulator. The LCA is well calibrated and compensates for its amplitude non-uniformity and nonlinear intensity responsivity. We measured the imaging contrasts of the coron- agraph system with the LCA only and without the DM deployed. Imaging contrasts of 10-4 and 10-5 can be reached at an inner working angular distance of 2.5 and 5A/D, respectively. A simulation shows that the phase errors on the coronagraph pupil limit the contrast performance. The contrast could be further improved if a DM is deployed to correct the phase errors induced by the LCA and coronagraph optics.

IMAGING OF EEG BY SPHERICAL HARMONIC ANALYSIS

A new three dimensional imaging method for electroencephalogram(EEG) is suggested. It consists of the solution of an inward spherical harmonic continuation. The principle of the new method is introduced in Section II, then a few numerical simulation tests are shown and the feasibility of the new method is confirmed by the simulation results.

Optical Antenna System Design for 3D Imaging Lidar

A new aspheric surface pre-collimation lenses system for the optical antenna of three-dimensional （3D） imaging of lidar has been optimally designed and simulated by optical design software CODE-V.Four kinds of aspheric surfaces spherical lenses including the sections of spherical,elliptical,hyperbola,and parabola have been researched.The optical system,including the elliptical cylinder lenses collimation and the optical antenna,can be realized less than 5 rad collimation angle for dot source semiconductor laser beam.

Diagnostic imaging:Morphological and eruptive disturbances in the permanent teeth

This paper reviewed the literature on newer threedimensional imaging techniques and their applications in diagnosis and treatment planning of various dental anomalies. Developmental anomalies can occur during any of the developmental stages and are manifested clinically after the tooth is fully formed. These dental anomalies may involve a single tooth, a group of teeth, or the entire dentition. Two-dimensional diagnosticimaging, including periapical, occlusal, panoramic, or cephalometric radiographs are essential in localization and management of morphological and eruptive disorders. However, due to their inherent limitations such as insufficient precision because of unusual projection errors and lack of information about spatial relationships, these methods are considered unreliable. Thus, the use of newer image acquisition techniques that allow comprehensive three dimensional imaging and visualization of dental abnormalities is highly recommended for making a confirmatory diagnosis. The significance of accurate endodontic, surgical and orthodontic treatment planning in dental abnormalities cannot be overstated as it pertains to critical anatomic landmarks such as proximity to adjacent teeth or the mandibular canal. The precise information on spatial relationships provided by multiplanar imaging helps the dental surgeon to establish more accurate diagnosis, management strategies and also increases the patient safety. This review highlights the use of high-end diagnostic imaging modalities in diagnosis of the various morphologic and eruptive dental abnormalities.

Multifunctional 2-(2-hydroxyphenyl)benzoxazoles: Ready synthesis,mechanochromism, fluorescence imaging, and OLEDs

Triphenylamine(TPA)-containing 2-(2-hydroxyphenyl)benzoxazoles(2a-2c)have been synthesized via a highly efficient rhodium-catalyzed C–H/C–H cross-coupling reaction.Compound 2a is a novel mechanofluorochromic material with blue-shifted mechanochromic properties.Compounds 2b and 2c presented opposite mechanochromic trends.For 2b,the enol-form emission enhanced,and the ketoform emission blue-shift after grinding.In contrast,2c exhibited the weak enol-form emission disappeared and the keto-form emission slightly red-shift after grinding treatments.The estrone-containing2b-based water-dispersed nanoparticles(NPs)exhibit apparent dual-emission and were applied for fluorescence images.In addition,bis(TPA)-containing 2c-based devices exhibit dual-emission with good performance and a singlet exciton yield of 92%,which breaks through the theoretical upper limit of 25%in conventional fluorescent OLEDs.This is one of the highest exciton utilization values recorded for the ESIPT molecules with a dual emission system.