Objective:To evaluate the intervention effect of diet, exercise and Jiangtang Bushen Recipe (JBR, 降糖补肾方), a Chinese herbal recipe, in preventing the progress of patients with impaired glucose tolerance ( IGT ) to...Objective:To evaluate the intervention effect of diet, exercise and Jiangtang Bushen Recipe (JBR, 降糖补肾方), a Chinese herbal recipe, in preventing the progress of patients with impaired glucose tolerance ( IGT ) to diabetes mellitus (DM) type 2. Methods: Fifty-one IGT patients with their diagnosis conformed to the diagnosis standard of WHO, 1999, were randomly divided into the control group (n = 26) and the TCM group (n=25). Patients in the control group attended to the educational course for DM and received dietotherapy and kinetotherapy, and to those in the TCM group, under these treatments, JBR was given additionally. Oral glucose tolerance test (OGTT), body weight index (BWI), levels of blood lipids and fasting insulin of all the patients were examined after 3 months, 6 months and 12 months of treatment. The total observation time was 1 year. Results:Except the 6 cases out of the 51 patients (11.7%), on whom the observa-tion discontinued, in the control group, as compared with before treatment, levels of fasting insulin and fasting blood glucose after treatment were not changed significantly ( P > 0. 05 ) , also insignificant difference was shown in levels of total cholesterol (TC) and triglyceride (TG), thoughthe two indexes lowered slightly after treatment (P>0. 05), but significant difference was shown in comparison of OGTT/2h, blood glucose and BWI (P<0. 05). While in the TCM group, fasting blood glucose was changed insignificantly (P> 0. 05) , but there was significant difference in comparison of fasting insulin, TC, BWI, OGTT/2h and plasma glucose levels (P<0. 01) respectively before and after treatment. At the end of the stud-y, the cumulative cases with conversion to diabetes were 3 (13. 6%) in the control group, and 1 (4. 3%) in the TCM group, x2 test showed insignificant difference in comparison of diabetes conversion rate between the two groups (P>0. 05), however, the TCM group showed a better year conversion rate of normal glucose tolerance than that in the control group (x2 = 8. 31, P<0. 01). Conclusion: TCM intervention is possibly effective in delaying the conversion of IGT to DM type 2, and plays integrative effeciency in impelling IGT patients to health. The favorable education and treatment of DM controlling, including dieto- and kineto-therapy may also be advantageous in IGT intervention, but could not be effective in blocking the advance of IGT.Original article on CJITWM (Chin) 2004 ;24 (4): 317展开更多
目的探究高膳食纤维限能干预对肥胖合并糖耐量异常患者体重和代谢指标的影响。方法前瞻性选取陕西省中医医院营养科门诊收治的60例肥胖合并糖耐量异常患者为研究对象,采用随机数字表法将其分为高膳食纤维限能组(30例,高膳食纤维限能干预...目的探究高膳食纤维限能干预对肥胖合并糖耐量异常患者体重和代谢指标的影响。方法前瞻性选取陕西省中医医院营养科门诊收治的60例肥胖合并糖耐量异常患者为研究对象,采用随机数字表法将其分为高膳食纤维限能组(30例,高膳食纤维限能干预)和常规饮食限能组(30例,常规饮食限能)。比较两组的干预效果。结果干预后,高膳食纤维限能组的甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FBG)、餐后2 h血糖(2 h PG)水平及稳态模型胰岛素抵抗指数(HOMA-IR)优于常规饮食限能组(P<0.05)。干预后,高膳食纤维限能组的腰围、体质量指数(BMI)、体脂率、内脏脂肪指数小于常规饮食限能组(P<0.05)。高膳食纤维限能组的治疗有效率高于常规饮食限能组,差异具有统计学意义(P<0.05)。结论高膳食纤维限能干预在肥胖合并糖耐量异常患者中的效果较好,可改善体重和代谢指标。展开更多
目的探讨行为转变理论(trans-theoretical model of behavior,TTM)在空腹血糖受损(impaired fasting glucose,IFG)人群生活方式干预中的应用效果。方法便利抽样法选取2012年3月至2013年3月在无锡市人民医院体检中心体检且符合IFG诊断的4...目的探讨行为转变理论(trans-theoretical model of behavior,TTM)在空腹血糖受损(impaired fasting glucose,IFG)人群生活方式干预中的应用效果。方法便利抽样法选取2012年3月至2013年3月在无锡市人民医院体检中心体检且符合IFG诊断的40例患者为研究对象。由研究团队根据TTM理论,制定综合、分阶段干预措施,一对一进行为期1年的运动、医学营养、糖尿病知识和心理等干预,使其逐步建立合理的饮食结构及适当的运动量,形成健康的生活方式。结果应用TTM方法干预生活方式后,IFG人群体质量指数(body mass index,BMI)、收缩压、舒张压、三酰甘油(triglyceride,TG)、总胆固醇(total cholesterol,TC)、低密度脂蛋白(low density lipoprotein,LDL)、空腹血糖(fasting plasma glucose,FPG)明显低于干预前,差异均有统计学意义(均P<0.05);但是腰围(waist circumference,WC)、高密度脂蛋白(high-density lipoprotein,HDL)较干预前好转不明显,差异均无统计学意义(均P>0.05)。干预后,IFG人群三餐饮食搭配合理例数明显高于干预前,差异有统计学意义(P<0.01)。每天摄入三种主要营养素、食用油、食盐、蔬菜摄入的合理例数明显高于干预前,差异有统计学意义(P<0.01)。IFG人群每天有效运动时间、总运动量、有效运动量均明显增加,与干预前比较,差异均有统计学意义(均P<0.01)。结论应用TTM干预有助于帮助IFG人群逐步建立和维持合理的膳食、适当的运动、改善代谢指标,从而降低发病危险因素,达到健康的生活方式,逐步从源头上控制2型糖尿病的发生与发展。展开更多
文摘Objective:To evaluate the intervention effect of diet, exercise and Jiangtang Bushen Recipe (JBR, 降糖补肾方), a Chinese herbal recipe, in preventing the progress of patients with impaired glucose tolerance ( IGT ) to diabetes mellitus (DM) type 2. Methods: Fifty-one IGT patients with their diagnosis conformed to the diagnosis standard of WHO, 1999, were randomly divided into the control group (n = 26) and the TCM group (n=25). Patients in the control group attended to the educational course for DM and received dietotherapy and kinetotherapy, and to those in the TCM group, under these treatments, JBR was given additionally. Oral glucose tolerance test (OGTT), body weight index (BWI), levels of blood lipids and fasting insulin of all the patients were examined after 3 months, 6 months and 12 months of treatment. The total observation time was 1 year. Results:Except the 6 cases out of the 51 patients (11.7%), on whom the observa-tion discontinued, in the control group, as compared with before treatment, levels of fasting insulin and fasting blood glucose after treatment were not changed significantly ( P > 0. 05 ) , also insignificant difference was shown in levels of total cholesterol (TC) and triglyceride (TG), thoughthe two indexes lowered slightly after treatment (P>0. 05), but significant difference was shown in comparison of OGTT/2h, blood glucose and BWI (P<0. 05). While in the TCM group, fasting blood glucose was changed insignificantly (P> 0. 05) , but there was significant difference in comparison of fasting insulin, TC, BWI, OGTT/2h and plasma glucose levels (P<0. 01) respectively before and after treatment. At the end of the stud-y, the cumulative cases with conversion to diabetes were 3 (13. 6%) in the control group, and 1 (4. 3%) in the TCM group, x2 test showed insignificant difference in comparison of diabetes conversion rate between the two groups (P>0. 05), however, the TCM group showed a better year conversion rate of normal glucose tolerance than that in the control group (x2 = 8. 31, P<0. 01). Conclusion: TCM intervention is possibly effective in delaying the conversion of IGT to DM type 2, and plays integrative effeciency in impelling IGT patients to health. The favorable education and treatment of DM controlling, including dieto- and kineto-therapy may also be advantageous in IGT intervention, but could not be effective in blocking the advance of IGT.Original article on CJITWM (Chin) 2004 ;24 (4): 317
文摘目的探究高膳食纤维限能干预对肥胖合并糖耐量异常患者体重和代谢指标的影响。方法前瞻性选取陕西省中医医院营养科门诊收治的60例肥胖合并糖耐量异常患者为研究对象,采用随机数字表法将其分为高膳食纤维限能组(30例,高膳食纤维限能干预)和常规饮食限能组(30例,常规饮食限能)。比较两组的干预效果。结果干预后,高膳食纤维限能组的甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FBG)、餐后2 h血糖(2 h PG)水平及稳态模型胰岛素抵抗指数(HOMA-IR)优于常规饮食限能组(P<0.05)。干预后,高膳食纤维限能组的腰围、体质量指数(BMI)、体脂率、内脏脂肪指数小于常规饮食限能组(P<0.05)。高膳食纤维限能组的治疗有效率高于常规饮食限能组,差异具有统计学意义(P<0.05)。结论高膳食纤维限能干预在肥胖合并糖耐量异常患者中的效果较好,可改善体重和代谢指标。
文摘目的探讨行为转变理论(trans-theoretical model of behavior,TTM)在空腹血糖受损(impaired fasting glucose,IFG)人群生活方式干预中的应用效果。方法便利抽样法选取2012年3月至2013年3月在无锡市人民医院体检中心体检且符合IFG诊断的40例患者为研究对象。由研究团队根据TTM理论,制定综合、分阶段干预措施,一对一进行为期1年的运动、医学营养、糖尿病知识和心理等干预,使其逐步建立合理的饮食结构及适当的运动量,形成健康的生活方式。结果应用TTM方法干预生活方式后,IFG人群体质量指数(body mass index,BMI)、收缩压、舒张压、三酰甘油(triglyceride,TG)、总胆固醇(total cholesterol,TC)、低密度脂蛋白(low density lipoprotein,LDL)、空腹血糖(fasting plasma glucose,FPG)明显低于干预前,差异均有统计学意义(均P<0.05);但是腰围(waist circumference,WC)、高密度脂蛋白(high-density lipoprotein,HDL)较干预前好转不明显,差异均无统计学意义(均P>0.05)。干预后,IFG人群三餐饮食搭配合理例数明显高于干预前,差异有统计学意义(P<0.01)。每天摄入三种主要营养素、食用油、食盐、蔬菜摄入的合理例数明显高于干预前,差异有统计学意义(P<0.01)。IFG人群每天有效运动时间、总运动量、有效运动量均明显增加,与干预前比较,差异均有统计学意义(均P<0.01)。结论应用TTM干预有助于帮助IFG人群逐步建立和维持合理的膳食、适当的运动、改善代谢指标,从而降低发病危险因素,达到健康的生活方式,逐步从源头上控制2型糖尿病的发生与发展。
