Based on updating of new generation weather radar software,compilation system of new generation weather radar case data could automatically back up data and compile radar case.Using C language and VC++6.0 development ...Based on updating of new generation weather radar software,compilation system of new generation weather radar case data could automatically back up data and compile radar case.Using C language and VC++6.0 development technology,the software realizes the automatic sorting and saving of radar base data,radar products and radar status information on different machines every day,and automatically creates various folders and files required for compiling data.By inputting the days,date,start and end times,renaming and compression of the base data,product data and status information could be automatically completed,to realize automation,batch,process and standardization of case data compilation.Since putting into the radar business,the operation has been stable and reliable.The working efficiency of business personnel has been improved,and a large number of manpower has been saved.It can be transplanted and popularized in other new generation weather radar stations.展开更多
BACKGROUND Lutetium has been shown to be an important potential innovation in pre-treated metastatic castration-resistant prostate cancer.Two clinical trials have evaluated lutetium thus far(therap and vision with 99 ...BACKGROUND Lutetium has been shown to be an important potential innovation in pre-treated metastatic castration-resistant prostate cancer.Two clinical trials have evaluated lutetium thus far(therap and vision with 99 and 385 patients,respectively),but their results are discordant.AIM To synthetize the available evidence on the effectiveness of lutetium in pre-treated metastatic castration-resistant prostate cancer;and to test the application of a new artificial intelligence technique that synthetizes effectiveness based on reconstructed patient-level data.METHODS We employed a new artificial intelligence method(shiny method)to pool the survival data of these two trials and evaluate to what extent the lutetium cohorts differed from one another.The shiny technique employs an original reconstruction of individual patient data from the Kaplan-Meier curves.The progression-free survival graphs of the two lutetium cohorts were analyzed and compared.RESULTS The hazard ratio estimated was in favor of the vision trial;the difference was statistically significant(P<0.001).These results indicate that further studies on lutetium are needed because the survival data of the two trials published thus far are conflicting.CONCLUSION Our study confirms the feasibility of reconstructing patient-level data from survival graphs in order to generate a survival statistics.展开更多
Background Chinese dietary reference intakes for calcium are largely based on foreign studies. We undertook meta- regression to estimate calcium requirements for Chinese adults derived from calcium balance data in Chi...Background Chinese dietary reference intakes for calcium are largely based on foreign studies. We undertook meta- regression to estimate calcium requirements for Chinese adults derived from calcium balance data in Chinese adults. Methods We searched PubMed, Cochrane CENTRAL, and SinoMed from inception to March 5, 2014, by using a structured search strategy. The bibliographies of any relevant papers and journals were also screened for potentially eligible studies. We extracted a standardized data set from studies in Chinese adults that reported calcium balance data. The relationship between calcium intake and output was examined by an individual participant data (IPD) and aggregate data (AD) meta-regression. Results We identified 11 metabolic studies in Chinese adults within 18-60 years of age. One hundred and forty-one IPD (n=35) expressed as mg/d, 127 IPD (n=32) expressed as mg.kg body wt-l-d-1, and 44 AD (n=132) expressed as mg/d were collected. The models predicted a neutral calcium balance (defined as calcium output (Y) equal to calcium intake (C)) at intakes of 460 mg/d (Y=0.60C+183.98) and 8.27 mg.kg body wt-l.d-1 (Y=0.60C+3.33) for IPD, or 409 mg/d (Y=0.66C+139.00) for AD. Calcium requirements at upper intakes were higher than that at lower intakes in all these models. Conclusion Calcium requirement for Chinese adults 18-60 years of age approximately ranges between 400 mg/d and 500 mg/d when consuming traditional plant-based Chinese diets.展开更多
We analyze the radio spectral index of blazars from the University of Michigan Radio Astronomy Observatory database,and find that there exists quasiperiodic activity in 2251+158.The long-term periodicity analysis is ...We analyze the radio spectral index of blazars from the University of Michigan Radio Astronomy Observatory database,and find that there exists quasiperiodic activity in 2251+158.The long-term periodicity analysis is accomplished by three methods,which are the Jurkevich method(Jurkevich),the discrete correlation function(DCF),and the Periodogram method(P).The results show that 2251+158 has two strong periodicities,which are P1=6.3±1.1 yr and P2=3.8±1.2 yr.展开更多
Publication biases and collection limitations are the main disadvantages of a traditional meta-analysis based on aggregate patient data(APD)from published articles.Individual patient data(IPD)meta-analysis,as the ...Publication biases and collection limitations are the main disadvantages of a traditional meta-analysis based on aggregate patient data(APD)from published articles.Individual patient data(IPD)meta-analysis,as the gold standard of systematic review,is a possible alternative in this context.However,the publications relative to IPD meta-analyses are still rare compared with the traditional ones,especially in the research oriented to Chinese medicine(CM).In this article,the strengths and detailed functioning of IPD meta-analysis are described.Furthermore,the need for IPD meta-analysis to assess the treatments based on CM was also discussed.Compared with the traditional APD meta-analysis,the IPD meta-analysis might give a more accurate and unbiased assessment and is worth to be recommended to CM researchers.展开更多
Quantities characterizing temporal property, e.g., power density, coherence, and time lag, can be defined and calculated directly in the time domain without using the Fourier transformation. Spectral hardness, variab...Quantities characterizing temporal property, e.g., power density, coherence, and time lag, can be defined and calculated directly in the time domain without using the Fourier transformation. Spectral hardness, variability duration, and correlation between different characteristic quamtities on different time scale can be studied in the time domain as well. The temporal analysis technique in the time domain is a powerful tool, particularly in studying rapid variability on short time scales (or in high frequencies). Results of studying variabilities of X-rays from Cyg X-1 with the analysis technique in the time domain and RXTE data reveal valuable clues to understanding production and propagation processes of X-rays and structure of accretion disk in the black hole system.展开更多
Modern methods of spectral estimation based on parametric time-series models are useful tools in power spectral analysis. We apply the autoregressive (AR) model to study quasi-periodic oscillations (QPOs). An empi...Modern methods of spectral estimation based on parametric time-series models are useful tools in power spectral analysis. We apply the autoregressive (AR) model to study quasi-periodic oscillations (QPOs). An empirical formula to estimate the expectation and standard deviation of the noise AR power densities is derived, which can be used to estimate the statistical significance of an apparent QPO peak in an AR spectrum. An iterative adding-noise algorithm in AR spectral analysis is proposed and applied to studying QPOs in the X-ray binary Cir X-1.展开更多
We simulated the R-band contribution of the host galaxy of TeV γ-ray BL Lac object Mrk 501 in different aperture sizes and seeing conditions. An intensive set of observations was acquired with the 1.02m optical teles...We simulated the R-band contribution of the host galaxy of TeV γ-ray BL Lac object Mrk 501 in different aperture sizes and seeing conditions. An intensive set of observations was acquired with the 1.02m optical telescope, managed by Yunnan Observatories, from 2010 May 15 to 18. Based on the host subtraction data usually used in the literature, the subtraction of host galaxy contamination results in significant seeing-brightness correlations. These correlations would lead to illusive large amplitude variations at short timescales, which will mask the intrinsic microvariability, thus giving rise to difficulty in detecting the intrinsic microvariability. Both aperture size and seeing condition influence the flux measurements, but the aperture size impacts the result more significantly. Based on the parameters of an elliptical galaxy provided in the literature, we simulated the host contributions of Mrk 501 in different aperture sizes and seeing conditions. Our simulation data of the host galaxy obviously weaken these significant seeing-brightness correlations for the host-subtracted brightness of Mrk 501, and can help us discover the intrinsic short timescale microvariability. The pure nuclear flux is -8.0 mJy in the R band, i.e., the AGN has a magnitude of R - 13.96 mag.展开更多
基金Supported by Scientific Research and Technology Development Project of Wuzhou Meteorological Bureau(WUQIKE2020001)。
文摘Based on updating of new generation weather radar software,compilation system of new generation weather radar case data could automatically back up data and compile radar case.Using C language and VC++6.0 development technology,the software realizes the automatic sorting and saving of radar base data,radar products and radar status information on different machines every day,and automatically creates various folders and files required for compiling data.By inputting the days,date,start and end times,renaming and compression of the base data,product data and status information could be automatically completed,to realize automation,batch,process and standardization of case data compilation.Since putting into the radar business,the operation has been stable and reliable.The working efficiency of business personnel has been improved,and a large number of manpower has been saved.It can be transplanted and popularized in other new generation weather radar stations.
文摘BACKGROUND Lutetium has been shown to be an important potential innovation in pre-treated metastatic castration-resistant prostate cancer.Two clinical trials have evaluated lutetium thus far(therap and vision with 99 and 385 patients,respectively),but their results are discordant.AIM To synthetize the available evidence on the effectiveness of lutetium in pre-treated metastatic castration-resistant prostate cancer;and to test the application of a new artificial intelligence technique that synthetizes effectiveness based on reconstructed patient-level data.METHODS We employed a new artificial intelligence method(shiny method)to pool the survival data of these two trials and evaluate to what extent the lutetium cohorts differed from one another.The shiny technique employs an original reconstruction of individual patient data from the Kaplan-Meier curves.The progression-free survival graphs of the two lutetium cohorts were analyzed and compared.RESULTS The hazard ratio estimated was in favor of the vision trial;the difference was statistically significant(P<0.001).These results indicate that further studies on lutetium are needed because the survival data of the two trials published thus far are conflicting.CONCLUSION Our study confirms the feasibility of reconstructing patient-level data from survival graphs in order to generate a survival statistics.
文摘Background Chinese dietary reference intakes for calcium are largely based on foreign studies. We undertook meta- regression to estimate calcium requirements for Chinese adults derived from calcium balance data in Chinese adults. Methods We searched PubMed, Cochrane CENTRAL, and SinoMed from inception to March 5, 2014, by using a structured search strategy. The bibliographies of any relevant papers and journals were also screened for potentially eligible studies. We extracted a standardized data set from studies in Chinese adults that reported calcium balance data. The relationship between calcium intake and output was examined by an individual participant data (IPD) and aggregate data (AD) meta-regression. Results We identified 11 metabolic studies in Chinese adults within 18-60 years of age. One hundred and forty-one IPD (n=35) expressed as mg/d, 127 IPD (n=32) expressed as mg.kg body wt-l-d-1, and 44 AD (n=132) expressed as mg/d were collected. The models predicted a neutral calcium balance (defined as calcium output (Y) equal to calcium intake (C)) at intakes of 460 mg/d (Y=0.60C+183.98) and 8.27 mg.kg body wt-l.d-1 (Y=0.60C+3.33) for IPD, or 409 mg/d (Y=0.66C+139.00) for AD. Calcium requirements at upper intakes were higher than that at lower intakes in all these models. Conclusion Calcium requirement for Chinese adults 18-60 years of age approximately ranges between 400 mg/d and 500 mg/d when consuming traditional plant-based Chinese diets.
基金supported by the National Natural Science Foundation of China (Grant No.10633010)the University of Michigan Radio Astronomy Observatory,which has been supported by the University of Michigan and the Nationa Science Foundation
文摘We analyze the radio spectral index of blazars from the University of Michigan Radio Astronomy Observatory database,and find that there exists quasiperiodic activity in 2251+158.The long-term periodicity analysis is accomplished by three methods,which are the Jurkevich method(Jurkevich),the discrete correlation function(DCF),and the Periodogram method(P).The results show that 2251+158 has two strong periodicities,which are P1=6.3±1.1 yr and P2=3.8±1.2 yr.
基金Supported by the Fundamental Research Funds for the CentralPublic Welfare Research Institutes of China(No.ZZ070818 andZ0259)National Natural Science Foundation of China(No.81072920 and 81303149)
文摘Publication biases and collection limitations are the main disadvantages of a traditional meta-analysis based on aggregate patient data(APD)from published articles.Individual patient data(IPD)meta-analysis,as the gold standard of systematic review,is a possible alternative in this context.However,the publications relative to IPD meta-analyses are still rare compared with the traditional ones,especially in the research oriented to Chinese medicine(CM).In this article,the strengths and detailed functioning of IPD meta-analysis are described.Furthermore,the need for IPD meta-analysis to assess the treatments based on CM was also discussed.Compared with the traditional APD meta-analysis,the IPD meta-analysis might give a more accurate and unbiased assessment and is worth to be recommended to CM researchers.
基金the Special Funds for Major State Basic Research Projects and by the National Natural Science Foundation of China
文摘Quantities characterizing temporal property, e.g., power density, coherence, and time lag, can be defined and calculated directly in the time domain without using the Fourier transformation. Spectral hardness, variability duration, and correlation between different characteristic quamtities on different time scale can be studied in the time domain as well. The temporal analysis technique in the time domain is a powerful tool, particularly in studying rapid variability on short time scales (or in high frequencies). Results of studying variabilities of X-rays from Cyg X-1 with the analysis technique in the time domain and RXTE data reveal valuable clues to understanding production and propagation processes of X-rays and structure of accretion disk in the black hole system.
基金Supported by the National Natural Science Foundation of China and by the State Basic Science Research Projects of China.
文摘Modern methods of spectral estimation based on parametric time-series models are useful tools in power spectral analysis. We apply the autoregressive (AR) model to study quasi-periodic oscillations (QPOs). An empirical formula to estimate the expectation and standard deviation of the noise AR power densities is derived, which can be used to estimate the statistical significance of an apparent QPO peak in an AR spectrum. An iterative adding-noise algorithm in AR spectral analysis is proposed and applied to studying QPOs in the X-ray binary Cir X-1.
基金financial supports of the Key Research Program of the CAS(Grant No.KJZD-EW-M06)the National Natural Science Foundation of China(NSFC+3 种基金Grant No.11433004)the Ministry of Science and Technology of China(2016YFA0400700)the financial supports of the NSFC(Grant Nos.11273052 and U1431228)the Youth Innovation Promotion Association,CAS
文摘We simulated the R-band contribution of the host galaxy of TeV γ-ray BL Lac object Mrk 501 in different aperture sizes and seeing conditions. An intensive set of observations was acquired with the 1.02m optical telescope, managed by Yunnan Observatories, from 2010 May 15 to 18. Based on the host subtraction data usually used in the literature, the subtraction of host galaxy contamination results in significant seeing-brightness correlations. These correlations would lead to illusive large amplitude variations at short timescales, which will mask the intrinsic microvariability, thus giving rise to difficulty in detecting the intrinsic microvariability. Both aperture size and seeing condition influence the flux measurements, but the aperture size impacts the result more significantly. Based on the parameters of an elliptical galaxy provided in the literature, we simulated the host contributions of Mrk 501 in different aperture sizes and seeing conditions. Our simulation data of the host galaxy obviously weaken these significant seeing-brightness correlations for the host-subtracted brightness of Mrk 501, and can help us discover the intrinsic short timescale microvariability. The pure nuclear flux is -8.0 mJy in the R band, i.e., the AGN has a magnitude of R - 13.96 mag.