目的研究个体化三维数字模型(three-dimension digital manikin,3D-DM)在内镜经鼻颞骨岩部解剖中的应用,探讨其临床应用价值。方法 10例(20侧)成人头部标本灌注后经CT扫描,将图像导入3Dview软件,重建出个体化3D-DM,运用"逆向骨窗形...目的研究个体化三维数字模型(three-dimension digital manikin,3D-DM)在内镜经鼻颞骨岩部解剖中的应用,探讨其临床应用价值。方法 10例(20侧)成人头部标本灌注后经CT扫描,将图像导入3Dview软件,重建出个体化3D-DM,运用"逆向骨窗形成"技术设计并模拟颞骨岩部骨窗形成。然后在3D-DM辅助下对颞骨岩部进行内镜解剖,对头部标本解剖与个体化3D-DM视野及相关测量进行比较。结果通过逆向骨窗形成技术可术前模拟颞骨岩部磨除,头部标本解剖与个体化3D-DM下视野高度一致,相关测量间比较无统计学差异。结论个体化3D-DM为内镜下经鼻入路暴露颞骨岩部提供详尽解剖数据,可以术前模拟颞骨岩部磨除,提高术中颞骨岩部磨除的准确性和安全性,对该手术入路的临床应用具重要指导意义。展开更多
Over the past decade,there has been notable progress in the systemic treatment of liver cancer.However,despite the emergence of new therapeutic strategies,they have not universally achieved success,with patients affli...Over the past decade,there has been notable progress in the systemic treatment of liver cancer.However,despite the emergence of new therapeutic strategies,they have not universally achieved success,with patients afflicted by liver diseases frequently displaying resistance to these treatments(1).Consequently,liver cancer remains a global health challenge,and hepatocellular carcinoma(HCC)stands as the fourth most common cause of cancer-related deaths globally,constituting 80-90%of primary liver cancer cases(2,3).This poses a substantial threat to both the survival and overall well-being of individuals.展开更多
Pancreatic cancer(PC)is a prevalent digestive malignancy worldwide and ranks as the fourth leading cause of cancer-related deaths globally.The incidence and mortality rates have been increasing annually,and due to its...Pancreatic cancer(PC)is a prevalent digestive malignancy worldwide and ranks as the fourth leading cause of cancer-related deaths globally.The incidence and mortality rates have been increasing annually,and due to its insidious onset and high malignancy,most patients are diagnosed at an advanced stage,with a 5-year survival rate of less than 8%(1).PC can be classified into endocrine and exocrine tumors,with over 95% of pancreatic malignant tumors originating from the exocrine portion of the pancreas.展开更多
文摘目的研究个体化三维数字模型(three-dimension digital manikin,3D-DM)在内镜经鼻颞骨岩部解剖中的应用,探讨其临床应用价值。方法 10例(20侧)成人头部标本灌注后经CT扫描,将图像导入3Dview软件,重建出个体化3D-DM,运用"逆向骨窗形成"技术设计并模拟颞骨岩部骨窗形成。然后在3D-DM辅助下对颞骨岩部进行内镜解剖,对头部标本解剖与个体化3D-DM视野及相关测量进行比较。结果通过逆向骨窗形成技术可术前模拟颞骨岩部磨除,头部标本解剖与个体化3D-DM下视野高度一致,相关测量间比较无统计学差异。结论个体化3D-DM为内镜下经鼻入路暴露颞骨岩部提供详尽解剖数据,可以术前模拟颞骨岩部磨除,提高术中颞骨岩部磨除的准确性和安全性,对该手术入路的临床应用具重要指导意义。
基金supported by the National Natural Science Foundation of China(No.32271470).
文摘Over the past decade,there has been notable progress in the systemic treatment of liver cancer.However,despite the emergence of new therapeutic strategies,they have not universally achieved success,with patients afflicted by liver diseases frequently displaying resistance to these treatments(1).Consequently,liver cancer remains a global health challenge,and hepatocellular carcinoma(HCC)stands as the fourth most common cause of cancer-related deaths globally,constituting 80-90%of primary liver cancer cases(2,3).This poses a substantial threat to both the survival and overall well-being of individuals.
基金supported by grants from National Natural Science Foundation of China(No.32271470)CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2021-I2M-1-058).
文摘Pancreatic cancer(PC)is a prevalent digestive malignancy worldwide and ranks as the fourth leading cause of cancer-related deaths globally.The incidence and mortality rates have been increasing annually,and due to its insidious onset and high malignancy,most patients are diagnosed at an advanced stage,with a 5-year survival rate of less than 8%(1).PC can be classified into endocrine and exocrine tumors,with over 95% of pancreatic malignant tumors originating from the exocrine portion of the pancreas.