BACKGROUND The aging of the population has become increasingly obvious in recent years,and the incidence of cerebral infarction has shown an increasing trend annually,with high death and disability rates.AIM To analyz...BACKGROUND The aging of the population has become increasingly obvious in recent years,and the incidence of cerebral infarction has shown an increasing trend annually,with high death and disability rates.AIM To analyze the effects of infarct location and volume on cognitive dysfunction in elderly patients with acute insular cerebral infarction.METHODS Between January 2020 and December 2023,we treated 98 cases of elderly acute insula,patients with cerebral infarction in the cerebral infarction acute phase(3-4 weeks)and for the course of 6 months in Montreal Cognitive Assessment Scale(MoCA)for screening of cognition.Notably,58 and 40 patients were placed in the cognitive impairment group and without-cognitive impairment group,respec-tively.In patients with cerebral infarction,magnetic resonance imaging was used to screen and clearly analyze the MoCA scores of two groups of patients with different infarctions,the relationship between the parts of the infarction volume,and analysis of acute insula cognitive disorder in elderly patients with cerebral RESULTS The number of patients with cognitive impairment in the basal ganglia and thalamus was significantly higher than that without cognitive impairment(P<0.05).The total infarct volume in the cognitive impairment group was higher than that in the non-cognitive impairment group,and the difference was statistically significant(P<0.05).The infarct volumes at different sites in the cognitive impairment group was higher than in the non-cognitive impairment group(P<0.05).In the cognitive impairment group,the infarct volumes in the basal ganglia,thalamus,and mixed lesions were negatively correlated with the total MoCA score,with correlation coefficients of-0.67,-0.73,and-0.77,respectively.CONCLUSION In elderly patients with acute insular infarction,infarction in the basal ganglia,thalamus,and mixed lesions were more likely to lead to cognitive dysfunction than in other areas,and patients with large infarct volumes were more likely to develop cognitive dysfunction.The infarct volume in the basal ganglia,thalamus,and mixed lesions was significantly negatively correlated with the MoCA score.展开更多
目的探讨老年(年龄60~70岁)急性岛叶梗死患者的梗死部位、梗死体积与临床预后的关系。方法选取2021年2~12月张家口市第一医院老年病科及全科医学科收治的100例老年急性岛叶梗死患者作为研究对象,受试者的脑梗死部位均运用核磁共振成像(m...目的探讨老年(年龄60~70岁)急性岛叶梗死患者的梗死部位、梗死体积与临床预后的关系。方法选取2021年2~12月张家口市第一医院老年病科及全科医学科收治的100例老年急性岛叶梗死患者作为研究对象,受试者的脑梗死部位均运用核磁共振成像(magnetic resonance imaging,MRI)筛查并明确,按Pullicino公式计算其脑梗死体积。根据脑梗死体积大小分组,脑梗死体积<3 cm^(3)组(A组)61例,脑梗死体积≥3 cm^(3)组(B组)39例,利用美国国立卫生院卒中量表(national institutesof health stroke scale,NIHSS)、蒙特利尔认知评估量表(montreal cognitive assessment,MoCA)、脑卒中改良Rankin量表(modifed rankin scale,mRS)、日常生活能力评估量表(activity of daily living scale,ADL)和简易精神状况量表(mini-mental state examination,MMSE)分别评估所有受试者入院时、出院时、出院后的神经功能缺损程度、认知、功能恢复、日常生活能力及精神状态进行综合评估。用秩和检验、Spearman等级相关性检验NIHSS、MoCA、mRS、ADL、MMSE评分与梗死部位、梗死体积的相关性。结果组内比较,A、B组入院时NIHSS、mRS评分依次高于出院时,出院后3、6个月时,MoCA、ADL、MMSE评分及TST剩余值依次低于出院时(P<0.05)。组间比较,A组入院时、出院期(出院时,出院后3、6个月)NIHSS、mRS评分显著低于B组,MoCA、ADL、MMSE评分及TST剩余值显著高于B组(P<0.05)。A组梗死部位(基底核、皮质、脑干、小脑、丘脑、混合病变)的TST剩余值均高于B组(P<0.05)。急性岛叶梗死患者的TST剩余值、NIHSS评分、mRA评分与脑梗死体积呈负相关(rs=-0.358、-0.425、-5.06,P=0.003、0.06、0.09),MoCA、ADL、MMSE评分与脑梗死体积呈正相关(rs=0.547、0.614、0.548,P均<0.001)。结论老年急性岛叶梗死患者的脑梗死部位与神经功能缺损程度、功能恢复呈负相关,与认知、日常生活能力及精神状态呈正相关,其中脑梗死体积与肢体运动功能呈负相关。展开更多
目的:探讨脑梗塞患者经外周静脉置入中心静脉导管(peripherally inserted central catheter,PICC)的知信行现状调查及影响因素,为健康教育提供理论依据。方法:选择行PICC的316例脑梗塞患者进行知信行现状调查,并分析其影响因素。结果:...目的:探讨脑梗塞患者经外周静脉置入中心静脉导管(peripherally inserted central catheter,PICC)的知信行现状调查及影响因素,为健康教育提供理论依据。方法:选择行PICC的316例脑梗塞患者进行知信行现状调查,并分析其影响因素。结果:共发放调查问卷316份,回收有效问卷316份,有效回收率为100%。316例脑梗塞PICC患者中男性182例,女性134例,知信行平均得分为(64.67±6.73)分,其中知识(9.17±0.83)分,态度(30.84±4.73)分,行为(24.66±4.47)分。单因素分析显示,PICC位置和性别对脑梗塞PICC患者的维护行为存在影响,文化水平对PICC患者知识存在影响,合并慢性病对脑梗塞PICC患者的态度存在影响,差异有统计学意义(P<0.05)。进一步多元回归分析显示,文化水平对脑梗塞PICC患者相关知识有影响(β=0.136),患者文化程度越高,知识得分越高;性别对脑梗塞PICC患者维护行为有影响(β=-0.103),行为得分女性患者较男性高,差异有统计学意义(P<0.05)。结论:脑梗塞PICC患者总体的知信行水平较高,文化程度较低;男性患者PICC知信行水平不高,应引起重视,对其进行有针对性的健康教育。展开更多
基金Zhangjiakou City Science and Technology Bureau Municipal Science and Technology Plan Project,No.2121136D.
文摘BACKGROUND The aging of the population has become increasingly obvious in recent years,and the incidence of cerebral infarction has shown an increasing trend annually,with high death and disability rates.AIM To analyze the effects of infarct location and volume on cognitive dysfunction in elderly patients with acute insular cerebral infarction.METHODS Between January 2020 and December 2023,we treated 98 cases of elderly acute insula,patients with cerebral infarction in the cerebral infarction acute phase(3-4 weeks)and for the course of 6 months in Montreal Cognitive Assessment Scale(MoCA)for screening of cognition.Notably,58 and 40 patients were placed in the cognitive impairment group and without-cognitive impairment group,respec-tively.In patients with cerebral infarction,magnetic resonance imaging was used to screen and clearly analyze the MoCA scores of two groups of patients with different infarctions,the relationship between the parts of the infarction volume,and analysis of acute insula cognitive disorder in elderly patients with cerebral RESULTS The number of patients with cognitive impairment in the basal ganglia and thalamus was significantly higher than that without cognitive impairment(P<0.05).The total infarct volume in the cognitive impairment group was higher than that in the non-cognitive impairment group,and the difference was statistically significant(P<0.05).The infarct volumes at different sites in the cognitive impairment group was higher than in the non-cognitive impairment group(P<0.05).In the cognitive impairment group,the infarct volumes in the basal ganglia,thalamus,and mixed lesions were negatively correlated with the total MoCA score,with correlation coefficients of-0.67,-0.73,and-0.77,respectively.CONCLUSION In elderly patients with acute insular infarction,infarction in the basal ganglia,thalamus,and mixed lesions were more likely to lead to cognitive dysfunction than in other areas,and patients with large infarct volumes were more likely to develop cognitive dysfunction.The infarct volume in the basal ganglia,thalamus,and mixed lesions was significantly negatively correlated with the MoCA score.
文摘目的探讨老年(年龄60~70岁)急性岛叶梗死患者的梗死部位、梗死体积与临床预后的关系。方法选取2021年2~12月张家口市第一医院老年病科及全科医学科收治的100例老年急性岛叶梗死患者作为研究对象,受试者的脑梗死部位均运用核磁共振成像(magnetic resonance imaging,MRI)筛查并明确,按Pullicino公式计算其脑梗死体积。根据脑梗死体积大小分组,脑梗死体积<3 cm^(3)组(A组)61例,脑梗死体积≥3 cm^(3)组(B组)39例,利用美国国立卫生院卒中量表(national institutesof health stroke scale,NIHSS)、蒙特利尔认知评估量表(montreal cognitive assessment,MoCA)、脑卒中改良Rankin量表(modifed rankin scale,mRS)、日常生活能力评估量表(activity of daily living scale,ADL)和简易精神状况量表(mini-mental state examination,MMSE)分别评估所有受试者入院时、出院时、出院后的神经功能缺损程度、认知、功能恢复、日常生活能力及精神状态进行综合评估。用秩和检验、Spearman等级相关性检验NIHSS、MoCA、mRS、ADL、MMSE评分与梗死部位、梗死体积的相关性。结果组内比较,A、B组入院时NIHSS、mRS评分依次高于出院时,出院后3、6个月时,MoCA、ADL、MMSE评分及TST剩余值依次低于出院时(P<0.05)。组间比较,A组入院时、出院期(出院时,出院后3、6个月)NIHSS、mRS评分显著低于B组,MoCA、ADL、MMSE评分及TST剩余值显著高于B组(P<0.05)。A组梗死部位(基底核、皮质、脑干、小脑、丘脑、混合病变)的TST剩余值均高于B组(P<0.05)。急性岛叶梗死患者的TST剩余值、NIHSS评分、mRA评分与脑梗死体积呈负相关(rs=-0.358、-0.425、-5.06,P=0.003、0.06、0.09),MoCA、ADL、MMSE评分与脑梗死体积呈正相关(rs=0.547、0.614、0.548,P均<0.001)。结论老年急性岛叶梗死患者的脑梗死部位与神经功能缺损程度、功能恢复呈负相关,与认知、日常生活能力及精神状态呈正相关,其中脑梗死体积与肢体运动功能呈负相关。
文摘目的:探讨脑梗塞患者经外周静脉置入中心静脉导管(peripherally inserted central catheter,PICC)的知信行现状调查及影响因素,为健康教育提供理论依据。方法:选择行PICC的316例脑梗塞患者进行知信行现状调查,并分析其影响因素。结果:共发放调查问卷316份,回收有效问卷316份,有效回收率为100%。316例脑梗塞PICC患者中男性182例,女性134例,知信行平均得分为(64.67±6.73)分,其中知识(9.17±0.83)分,态度(30.84±4.73)分,行为(24.66±4.47)分。单因素分析显示,PICC位置和性别对脑梗塞PICC患者的维护行为存在影响,文化水平对PICC患者知识存在影响,合并慢性病对脑梗塞PICC患者的态度存在影响,差异有统计学意义(P<0.05)。进一步多元回归分析显示,文化水平对脑梗塞PICC患者相关知识有影响(β=0.136),患者文化程度越高,知识得分越高;性别对脑梗塞PICC患者维护行为有影响(β=-0.103),行为得分女性患者较男性高,差异有统计学意义(P<0.05)。结论:脑梗塞PICC患者总体的知信行水平较高,文化程度较低;男性患者PICC知信行水平不高,应引起重视,对其进行有针对性的健康教育。
