The coronavirus disease 2019(COVID-19)pandemic has been ongoing for more than 3 years,with an enormous impact on global health and economies.In some patients,symptoms and signs may remain after recovery from severe ac...The coronavirus disease 2019(COVID-19)pandemic has been ongoing for more than 3 years,with an enormous impact on global health and economies.In some patients,symptoms and signs may remain after recovery from severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,which cannot be explained by an alter-nate diagnosis;this condition has been defined as long COVID.Long COVID may exist in patients with both mild and severe disease and is prevalent after infection with different SARS-CoV-2 variants.The most common symp-toms include fatigue,dyspnea,and other symptoms involving multiple organs.Vaccination results in lower rates of long COVID.To date,the mechanisms of long COVID remain unclear.In this narrative review,we summarized the clinical presentations and current evidence regarding the pathogenesis of long COVID.展开更多
基金This work was supported by the Fundamental Research Funds for the Central Universities(No.3332022078)Chinese Academy of Medical Sciences Institute of Respiratory Medicine Young Scientist Fund(No.2023-ZF-12)the Natural Science Foundation of Shandong Province(No.ZR2021MH266).
文摘The coronavirus disease 2019(COVID-19)pandemic has been ongoing for more than 3 years,with an enormous impact on global health and economies.In some patients,symptoms and signs may remain after recovery from severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,which cannot be explained by an alter-nate diagnosis;this condition has been defined as long COVID.Long COVID may exist in patients with both mild and severe disease and is prevalent after infection with different SARS-CoV-2 variants.The most common symp-toms include fatigue,dyspnea,and other symptoms involving multiple organs.Vaccination results in lower rates of long COVID.To date,the mechanisms of long COVID remain unclear.In this narrative review,we summarized the clinical presentations and current evidence regarding the pathogenesis of long COVID.
