Background Transcatheter bronchial artery embolization （BAE） is widely used for the treatment of hemoptysis and the immediate success rate is high, but there are still some hemorrhage recurrences. One of the common ...Background Transcatheter bronchial artery embolization （BAE） is widely used for the treatment of hemoptysis and the immediate success rate is high, but there are still some hemorrhage recurrences. One of the common reasons for failure of BAE is collateral branches as blood supply. The inferior phrenic artery （IPA） is one of the most common collateral branches that is scarcely reported. Our purpose was to observe manifestations of IPA supplying to hemoptysis and evaluate the efficacy and safety of IPA embolization. Methods Angiography during interventional treatment of 178 hemoptysis patients in the past 7 years confirmed that IPA hemorrhage resulted in hemoptysis in 25 patients （26-67 years old） who had： lung cancer （11 patients）, bronchiectasis （11 patients）, chronic lung inflammation （2 patients）, and pulmonary tuberculosis （1 patient）. Among the 25 patients, 7 patients had twice interventional operations within one week and 6 patients still experienced intraoperative hemoptysis after conventional embolization of the bronchial artery, the internal thoracic artery, and the intercostal artery, then had the second interventional operation immediately. The total number of cases were 191. Selective embolization of the IPA was performed using polyvinyl alcohol microspheres, gelatin sponge particles, and microcoil. The safety and clinical significance of IPA embolization were evaluated. The Pearson X2 test and Fisher＇s exact probability test were used in this study. Results Selective IPA angiography showed increased diameter of the IPA, disorganization of the branches, and varying degrees of angiogenesis. In 11 cases, contrast material was seen in vessels supplying the tumor and in the tumor. In 9 cases, contrast material had leaked into the area supplied by the IPA; in 8 cases, non-specific flake-like deposits of contrast material were seen; and in 14 cases, abnormal communication or shunt was visualized. Lesions were closely related to the pleura in 25 patients. Fifteen lesions were close to the diaphragmatic pleura, seven close to the mediastinal pleura, and three close to the lateral pleura of the lower lung. Eleven cases had inferior thoracic pleural thickening and adhesions. The IPA was embolized in 25 cases, and the success rate of hemostasis was 100%. The IPA was not embolized in the other 166 cases, and the success rate of hemostasis was 92.17 %. In the 25 cases with IPA embolization, the involvement of the IPA in the blood supply of the hemoptysis was correlated with the duration of the disease （P=0.0344）. The involvement of IPA in the blood supply of the hemoptysis was not correlated with the characteristic of the lung lesions （benign or malignant） （P=1.0000）. Duration of follow-up was 8 months to 5 years. Hemoptysis recurred in four patients 1,2, 3, and 6 months after interventional operation, respectively, and was controlled by conservative treatment. Twenty-one patients had no recurrence of hemoptysis. Conclusions Bleeding from the IPA can result in hemoptysis and failure of BAE in the treatment of hemoptysis. If IPA hemorrhage contributes to hemoptysis, supplementary IPA embolization may be a safe and effective treatment.展开更多
目的评价进展期胃底贲门癌行腹主动脉、腹腔动脉、胃左动脉(LGA)及左膈下动脉(LIPA)造影的意义;探讨LGA and LIPA联合化疗栓塞对进展期胃底贲门癌的价值。方法18例经DSA确认有LGA and LIPA均参与胃底贲门癌供血者行二动脉化疗栓塞术,LG...目的评价进展期胃底贲门癌行腹主动脉、腹腔动脉、胃左动脉(LGA)及左膈下动脉(LIPA)造影的意义;探讨LGA and LIPA联合化疗栓塞对进展期胃底贲门癌的价值。方法18例经DSA确认有LGA and LIPA均参与胃底贲门癌供血者行二动脉化疗栓塞术,LGA共行70次TACE,LIPA共行65次TACE。术前除胃镜和钡餐检查外均行多层螺旋CT三期增强扫描,术中常规行腹主动脉、腹腔动脉及LGA and LIPA造影,准确估计腔内外病变情况,在确认供血范围后将导管逐一超选择至LGA and LIPA支,再分别用碘油-抗癌乳剂栓塞肿瘤末梢血管,然后注入明胶海。结果LGA and LIPA联合化疗栓塞后1、2年、3年生存率分别为88.9%(16/18)、55.6%(10/18)、38.9%(7/18);有4例均行LGA and LIPA化疗栓塞2-3次后行外科手术根治术,已存活4年和5年,目前仍在随访中。未出现一例严重并发症。结论进展期胃底贲门癌术中行腹主动脉、腹腔动脉及LGA and LIPA造影能进一步明确肿瘤的T分期;行LGA and LIPA联合化疗栓塞是一种疗效好、安全性高、科学合理、并发症少且多为自限性的治疗方法。展开更多
文摘Background Transcatheter bronchial artery embolization （BAE） is widely used for the treatment of hemoptysis and the immediate success rate is high, but there are still some hemorrhage recurrences. One of the common reasons for failure of BAE is collateral branches as blood supply. The inferior phrenic artery （IPA） is one of the most common collateral branches that is scarcely reported. Our purpose was to observe manifestations of IPA supplying to hemoptysis and evaluate the efficacy and safety of IPA embolization. Methods Angiography during interventional treatment of 178 hemoptysis patients in the past 7 years confirmed that IPA hemorrhage resulted in hemoptysis in 25 patients （26-67 years old） who had： lung cancer （11 patients）, bronchiectasis （11 patients）, chronic lung inflammation （2 patients）, and pulmonary tuberculosis （1 patient）. Among the 25 patients, 7 patients had twice interventional operations within one week and 6 patients still experienced intraoperative hemoptysis after conventional embolization of the bronchial artery, the internal thoracic artery, and the intercostal artery, then had the second interventional operation immediately. The total number of cases were 191. Selective embolization of the IPA was performed using polyvinyl alcohol microspheres, gelatin sponge particles, and microcoil. The safety and clinical significance of IPA embolization were evaluated. The Pearson X2 test and Fisher＇s exact probability test were used in this study. Results Selective IPA angiography showed increased diameter of the IPA, disorganization of the branches, and varying degrees of angiogenesis. In 11 cases, contrast material was seen in vessels supplying the tumor and in the tumor. In 9 cases, contrast material had leaked into the area supplied by the IPA; in 8 cases, non-specific flake-like deposits of contrast material were seen; and in 14 cases, abnormal communication or shunt was visualized. Lesions were closely related to the pleura in 25 patients. Fifteen lesions were close to the diaphragmatic pleura, seven close to the mediastinal pleura, and three close to the lateral pleura of the lower lung. Eleven cases had inferior thoracic pleural thickening and adhesions. The IPA was embolized in 25 cases, and the success rate of hemostasis was 100%. The IPA was not embolized in the other 166 cases, and the success rate of hemostasis was 92.17 %. In the 25 cases with IPA embolization, the involvement of the IPA in the blood supply of the hemoptysis was correlated with the duration of the disease （P=0.0344）. The involvement of IPA in the blood supply of the hemoptysis was not correlated with the characteristic of the lung lesions （benign or malignant） （P=1.0000）. Duration of follow-up was 8 months to 5 years. Hemoptysis recurred in four patients 1,2, 3, and 6 months after interventional operation, respectively, and was controlled by conservative treatment. Twenty-one patients had no recurrence of hemoptysis. Conclusions Bleeding from the IPA can result in hemoptysis and failure of BAE in the treatment of hemoptysis. If IPA hemorrhage contributes to hemoptysis, supplementary IPA embolization may be a safe and effective treatment.
文摘目的评价进展期胃底贲门癌行腹主动脉、腹腔动脉、胃左动脉(LGA)及左膈下动脉(LIPA)造影的意义;探讨LGA and LIPA联合化疗栓塞对进展期胃底贲门癌的价值。方法18例经DSA确认有LGA and LIPA均参与胃底贲门癌供血者行二动脉化疗栓塞术,LGA共行70次TACE,LIPA共行65次TACE。术前除胃镜和钡餐检查外均行多层螺旋CT三期增强扫描,术中常规行腹主动脉、腹腔动脉及LGA and LIPA造影,准确估计腔内外病变情况,在确认供血范围后将导管逐一超选择至LGA and LIPA支,再分别用碘油-抗癌乳剂栓塞肿瘤末梢血管,然后注入明胶海。结果LGA and LIPA联合化疗栓塞后1、2年、3年生存率分别为88.9%(16/18)、55.6%(10/18)、38.9%(7/18);有4例均行LGA and LIPA化疗栓塞2-3次后行外科手术根治术,已存活4年和5年,目前仍在随访中。未出现一例严重并发症。结论进展期胃底贲门癌术中行腹主动脉、腹腔动脉及LGA and LIPA造影能进一步明确肿瘤的T分期;行LGA and LIPA联合化疗栓塞是一种疗效好、安全性高、科学合理、并发症少且多为自限性的治疗方法。
