2020年,国家药品监督管理局颁布了《模型引导的药物研发技术指导原则》等技术指南,为建模与模拟技术在新药研发中的应用提供了技术指导。2022年7月,为了解国内新药研发企业在模型引导的药物研发(model-informed drug development,MIDD)...2020年,国家药品监督管理局颁布了《模型引导的药物研发技术指导原则》等技术指南,为建模与模拟技术在新药研发中的应用提供了技术指导。2022年7月,为了解国内新药研发企业在模型引导的药物研发(model-informed drug development,MIDD)方面的实践情况,药品审评中心对制药工业界在新药研发中应用MIDD的实践能力进行了问卷调查。本文主要针对收集到的企业反馈数据,分析MIDD技术在国内制药工业界的实践情况,并对当前仍存在的部分问题进行简要讨论。展开更多
Modern society is called the stress society, there has been a growing interest in comfortable living space. Therefore, a lot of studies using biological information have been done to quantitatively assess the effects ...Modern society is called the stress society, there has been a growing interest in comfortable living space. Therefore, a lot of studies using biological information have been done to quantitatively assess the effects on the human body in recent years. This study verified quantitatively difference between healing effect and stress reduction effect of sea space and general street space using an inexpensive EEG (Electroencephalogram) machine. The purpose of this study is to verify quantitatively healing effect and stress reduction effect of sea space using the EEG measurement from the psychological analysis by questionnaire survey and the SD (Semantic Differential) method. As a result, EEG and questionnaire results, psychological analysis results can be seen to match, and the effectiveness of the EEG measurement was confirmed.展开更多
文摘2020年,国家药品监督管理局颁布了《模型引导的药物研发技术指导原则》等技术指南,为建模与模拟技术在新药研发中的应用提供了技术指导。2022年7月,为了解国内新药研发企业在模型引导的药物研发(model-informed drug development,MIDD)方面的实践情况,药品审评中心对制药工业界在新药研发中应用MIDD的实践能力进行了问卷调查。本文主要针对收集到的企业反馈数据,分析MIDD技术在国内制药工业界的实践情况,并对当前仍存在的部分问题进行简要讨论。
文摘Modern society is called the stress society, there has been a growing interest in comfortable living space. Therefore, a lot of studies using biological information have been done to quantitatively assess the effects on the human body in recent years. This study verified quantitatively difference between healing effect and stress reduction effect of sea space and general street space using an inexpensive EEG (Electroencephalogram) machine. The purpose of this study is to verify quantitatively healing effect and stress reduction effect of sea space using the EEG measurement from the psychological analysis by questionnaire survey and the SD (Semantic Differential) method. As a result, EEG and questionnaire results, psychological analysis results can be seen to match, and the effectiveness of the EEG measurement was confirmed.
