The occurrence,inheritance,and segregation of complex genomic structural variation in synthetic Brassica napus

"Synthetic"allopolyploids recreated by interspecific hybridization play an important role in providing novel genomic variation for crop improvement.Such synthetic allopolyploids often undergo rapid genomic structural variation(SV).However,how such SV arises,is inherited and fixed,and how it affects important traits,has rarely been comprehensively and quantitively studied in advanced generation synthetic lines.A better understanding of these processes will aid breeders in knowing how to best utilize synthetic allopolyploids in breeding programs.Here,we analyzed three genetic mapping populations(735 DH lines)derived from crosses between advanced synthetic and conventional Brassica napus(rapeseed)lines,using whole-genome sequencing to determine genome composition.We observed high tolerance of large structural variants,particularly toward the telomeres,and preferential selection for balanced homoeologous exchanges(duplication/deletion events between the A and C genomes resulting in retention of gene/chromosome dosage between homoeologous chromosome pairs),including stable events involving whole chromosomes("pseudoeuploidy").Given the experimental design(all three populations shared a common parent),we were able to observe that parental SV was regularly inherited,showed genetic hitchhiking effects on segregation,and was one of the major factors inducing adjacent novel and larger SV.Surprisingly,novel SV occurred at low frequencies with no significant impacts on observed fertility and yield-related traits in the advanced generation synthetic lines.However,incorporating genome-wide SV in linkage mapping explained significantly more genetic variance for traits.Our results provide a framework for detecting and understanding the occurrence and inheritance of genomic SV in breeding programs,and support the use of synthetic parents as an important source of novel trait variation.

Exploration of the Inheritance and Innovation Carrier of National Culture in the Teaching Model of Art Design Major in Higher Vocational Colleges:Integrating Lijiang Baisha Murals into Higher Vocational Art Design Curriculum System

This study aims to further promote the inheritance and innovative development of intangible cultural heritage in Yunnan Province,promote the protection,inheritance,integration,and innovation of ethnic culture in Lijiang,strengthen the protection and inheritance of Baisha murals in Lijiang,and change the teaching of art design majors in vocational colleges in Yunnan.Given the lack of traditional Chinese culture and local ethnic culture,this article focuses on the teaching of art design majors in Yunnan vocational colleges.It explores the construction model of the cultural inheritance and innovation carrier of Lijiang Baisha murals to meet the spiritual and cultural needs of the local people,and efforts will be made to promote the high-quality development of the Baisha ethnic area in Lijiang.

Higher rates of autism and attention deficit/hyperactivity disorder in American children:Are food quality issues impacting epigenetic inheritance?

In the United States,schools offer special education services to children who are diagnosed with a learning or neurodevelopmental disorder and have difficulty meeting their learning goals.Pediatricians may play a key role in helping children access special education services.The number of children ages 6-21 in the United States receiving special education services increased 10.4%from 2006 to 2021.Children receiving special education services under the autism category increased 242%during the same period.The demand for special education services for children under the developmental delay and other health impaired categories increased by 184%and 83%respectively.Although student enrollment in American schools has remained stable since 2006,the percentage distribution of children receiving special education services nearly tripled for the autism category and quadrupled for the developmental delay category by 2021.Allowable heavy metal residues remain persistent in the American food supply due to food ingredient manufacturing processes.Numerous clinical trial data indicate heavy metal exposures and poor diet are the primary epigenetic factors responsible for the autism and attention deficit hyperactivity disorder epidemics.Dietary heavy metal exposures,especially inorganic mercury and lead may impact gene behavior across generations.In 2021,the United States Congress found heavy metal residues problematic in the American food supply but took no legislative action.Mandatory health warning labels on select foods may be the only way to reduce dietary heavy metal exposures and improve child learning across generations.

Lack of fitness cost and inheritance of resistance to abamectin based on the establishment of a near-isogenic strain of Tetranychus urticae

Many populations of the two-spotted spider mite, Tetranychus urticae Koch, have developed high levels of resistance to the pesticide abamectin in China and other countries. This study developed a near-isogenic line to understand better the inheritance, cross-resistance, and fitness costs associated with abamectin resistance in the field population of T. urticae in China. We introduced the trait that confers extremely high abamectin resistance in a field-collected population of T. urticae into a susceptible laboratory strain(IPP-SS) to generate an abamectin-resistant near-isogenic line(NIL-Aba).This process was carried out through multiple backcrossing to IPP-SS and via parthenogenesis and abamectin screening. Compared with IPP-SS, the NIL-Aba strain had a 25 147-fold resistance to abamectin and a high level of cross-resistance to bifenthrin(288.17-fold), an intermediate level to emamectin benzoate(42.57-fold), and low levels to bifenazate, chlorfenapyr, cyflumetofen, cyenopyrafen, and cyetpyrafen with resistance ranging from 3.18-to 9.31-fold.But it had no cross-resistance to profenofos. The resistance to abamectin in NIL-Aba was autosomal, incompletely dominant, and polygenic. Based on two sex life table parameters, no fitness cost was found in NIL-Aba. Establishing the NIL-Aba strain provides a reliable basis for an in-depth study of abamectin resistance in T. urticae. New information on toxicological characteristics and fitness cost should facilitate the management of abamectin resistance in field populations of T. urticae.

Research on Inheritance and Innovation of Children's Folk Sports Culture in the Junction Area Between Chongqing and Hubei

This paper examines the current status and development dilemma of the children’s folk sports culture in the junction area between Chongqing and Hubei with reference to relevant literature.After the literature review and summary,the study finds there are several factors restricting the inheritance and development of the children’s folk sports culture in the area,including insufficiency of theoretical analysis,weak public support in cities,blind imitation of modern sports culture,and absence of policy support.To address the above problems,we put forward several suggestions to promote the inheritance and development of children’s folk sports game culture.First,we should focus on the theoretical research and cultural dissemination of children’s folk sports culture.Second,we should improve the basic rules of children’s folk sports games.Third,importance should be attached to government support in developing children’s folk sports game culture.Fourth,we should ensure the continuation and inheritance of children’s folk sports culture via school activities.Finally,we should carry forward children’s folk sports culture and explore ways to develop excellent cultural tourism.

Application and Practice of Traditional Chinese Medicine Characteristic Technology Inheritance in Research and Development of Traditional Chinese Medicine Preparations in Medical Institutions

Medical institution preparations play an important role in the development of hospitals,being one of the main forms of traditional Chinese medicine clinical characteristic medication,as well as an important carrier for the inheritance and innovation of traditional Chinese medicine.In recent years,the research and development of traditional Chinese medicine preparations has become a hot spot in the research and development of preparations by medical institutions.Traditional Chinese medicine preparations prepared by traditional processes and their entrusted preparation matters have changed from the current licensing management to filing management.The registration model of traditional Chinese medicine preparations has undergone significant changes,emphasizing more on real data and evaluation results from the objective world,respecting traditional medication experience,and emphasizing the inheritance and innovative development of traditional technological experience.In the process of following teachers in the inheritance project of traditional Chinese medicine,we combined the inheritance of traditional Chinese medicine characteristic technology with the research and development practice of traditional Chinese medicine preparations in medical institutions,and focused on the analysis and discussion of technical problems such as prescription screening,dosage form selection,process route design and clinical observation of traditional Chinese medicine preparations,hoping to provide reference for scholars in the same field of traditional Chinese medicine.

Inheritance and Innovation of Regional Cultures in Architectural Designs of Yichang

Against the background of outstanding traditional Chinese culture and the innovation-drivendevelopment strategy, this study analyzed regional cultures of Yichang where ancient Ba and Chu culturesmet and blended, proposed regional architectural designs adapted to modern conditions, fully clarified thedesign concepts of “deeply exploring, highly condensing, making the past serve the present, inheriting andinnovating” through analyzing the design cases in many regional architectural projects. The paper aimedat further inheriting and developing the outstanding traditional Chinese cultures, and provided theoreticalreferences for future designs.

On ecological inheritance construction of intangible cultural heritage in era of intellectual media

It is known that intangible cultural heritage is an important resource of the cultural soft power in a country, and it is also an organic component and representation of national history, spirit and cohesion.Therefore, a good inheritance of intangible cultural heritage is of great significance for carrying forward the ethical basis of human culture as well as maintaining its value core. Nowadays, the rapid intelligentization of media has ushered in the era of intellectual media, with characteristics of “massive media, man-machine integration and self-evolution”. In the era of intellectual media, traces of intelligent technologies can be seen everywhere, and the ecology of the inheritance of intangible cultural heritage has been reconstructed. Under this circumstance, the author firstly makes clarification of the advancement of the era, which has given a new logic of intangible cultural heritage inheritance, and various intelligent powers should be developed including intelligent acquisition, processing and judgement ability of content value. Then, the technology empowerment is analyzed, which has made reconstruction of intangible cultural heritage inheritance: while being digitalized,the inheritance of intangible cultural heritage has become systematized in way of “Points, Lines and Planes” at the same time. Therefore, the communication ecology of intangible cultural heritage could be established as a new approach of inheritance via all sorts of intelligent technologies, so as to promote Chinese cultural soft power and enhance our national image in the long run.

Discussion on Cultural Inheritance of Water Parks in the Yellow River Basin

At the Symposium on Ecological Protection and High-quality Development of the Yellow River Basin, General Secretary Xi Jinping pointed out that "it should deeply explore the time value contained in the Yellow River culture, tell the story of the Yellow River well, and protect, inherit and carry forward the Yellow River culture". Water park is an important carrier of the Yellow River culture transmission. In this paper, the basic characteristics and regional distribution of water parks in the Yellow River basin are analyzed. For the problems faced by cultural heritage of water parks in the Yellow River basin, from three aspects of exploring and integrating the connotation, innovating communication methods, and shaping brand IP, cultural heritage of water parks in the Yellow River basin is discussed. It is beneficial to carry forward the Yellow River culture, and better meet the spiritual and cultural needs of the people.

Inheritance and Development of Guangxi Minority Musical Instruments and Their Integration With Operas

The traditional musical instrument of minorities converges the evolution of ethnic group culture and history,and ethnic musical instruments are a core component of minority culture.The traditional instruments of Guangxi minorities are rich and varied,and an all-round cultural inheritance and protection mechanism should be used for ethnic musical instruments,so that the performance form of classical musical instruments of minorities can be more widely understood and mastered.Therefore,in this paper,we discuss the specific practice idea of the inheritance and development of classical musical instruments of Guangxi minorities,and facilitate the innovation of development path of ethnic musical instruments by taking the inheritance form of integrating musical instruments with operas.

A Study on the Inheritance Path of Red Music in Universities Under the Multicultural Background

Red music culture is a cultural form created by the people led by the Communist Party of China(CPC)in the process of revolution,construction,and reform.The inheritance and dissemination of this cultural form in universities,especially in the context of multiculturalism,has important social and cultural value.This study takes the red music culture in Shanghai as the research carrier,and explores the inheritance path of red music in universities through background investigation,theoretical research,specific practice,and achievement display.The research results show that red music culture can be effectively inherited and promoted by strengthening the construction of the red music culture cloud platform in universities,integrating red music culture resources into the campus environment,and promoting it in Chinese,English,and Japanese on social media.In addition,this study also explores the effective role of red music culture in establishing correct ideals and beliefs among college students.

School Education and Inheritance of Ethnic Culture in Minority Areas-Take School Education in Tibetan Areas as an Example

Ethnic education is an important way to inherit ethnic culture.Under the background of cultural globalization and cultural diversification,minority cultures are facing the danger of extinction and change.Schools in minority areas give full play to their own advantages and become the main places to train students to master ethnic culture in a purposeful,planned,and organized way.However,there are also many problems in school education in the inheritance of national culture,such as the content of school education and national culture cannot be effectively integrated,teachers lack scientific and effective teaching methods,teaching activities content cannot be flexibly used.In this regard,we should excavate the national cultural resources in school education,improve the professional quality and skills of teachers,and enhance the national consciousness of teachers,so as to improve the quality of school education and realize the effective inheritance of national culture.Taking Tibetan areas as an example,this paper analyzes the advantages,existing problems,and solutions of the school in Tibetan cultural traditions.

The Inheritance and Deviation of the Subjective Construction“You Bei X Dao(有被X到)”

Sentence“bei”(“被”字句)and“bei xx”(被xx)provide syntactic and semantic basis for the generation of the construction“You Bei X Dao(有被x到)”.They are in a continuum and have family similarity.The sentence“bei”is a typical member,while“bei xx”is an atypical member.Because the construction“You Bei X Dao”has a single function and less attention,it is at the edge of the continuum and is a marginal member.However,it has certain research value in the inheritance and innovation of“bei”and“bei xx”.

The Aesthetic Inheritance of the Mao Dun Literature Prize in the Flux-Take Xu Mao and His Daughters and A Tale of the Wind as Examples

The Mao Dun Literature Prize is one of the well-known literary awards in China,and in the process of selection over the years,the Mao Dun Literature Prize has developed its own aesthetic orientation.A comparison is made between the early generation of Xu Mao and His Daughters and the recent award-winning work,A Tale of the Wind,to discover the aesthetic heritage in its flux,which is enlightening for the literary criticism and an orientation for the literary creators.

Contemporary Inheritance of the Legend of ZHANG Zhongjing's Practicing Medicine in the Clinic

From the perspective of narratology, this paper explores the contemporary inheritance of the medical legacy of Zhang Zhongjing's practice medicine in the clinic. Its inheritance mode includes: the enrichment of language and characters and the narratio of romance, the spatial reductive narratio of cultural landscape, the body expressive narratio of ritual behavior. This makes the legend more concerned with the real society, enhances the regional cultural image, develops the local economy, and confidences to the practices role of carrying forward the response and mission of practicing medicine to save people. Compared with the previous academic circle, which previous focus on the textual research of the dispute over its historical authentication, or focus on the retrospective study of its historical origin, this paper is based on the research perspective of historical inheritance, which is constructive to the living inheritance and protection of legends.

非遗视角下苗族蜡染技艺的数字化传承

蜡染技艺作为中国非物质文化遗产的重要组成部分,正面临着传承困境和现代化转型的挑战。文章聚焦于探索数字化时代背景下非遗苗族蜡染技艺的创新传承方法,分析了非遗蜡染技艺传承中存在的闭塞性、局限性和单一性问题,提出建立多元化技艺体验中心、开发数字化技艺传承渠道、完善全面化技艺反馈机制等举措,助力非遗苗族蜡染实现现代化转型。

我国生态文明思想的经济发展历程与实践检验

我国把节约资源和保护环境确立为基本国策,把可持续发展确立为国家战略,大力推进社会主义生态文明建设。我国的生态文明建设是基于中华文明“天人合一”的历史文化传承,结合马克思主义理论中国化、时代化,致力于实现经济社会与绿色发展的和谐统一。笔者通过文献调查,梳理了中华人民共和国成立以来生态文明思想的传承发展脉络。生态文明建设经历了从起步、发展到完善三个阶段:起步阶段,在我国生态文明思想史上具有开创与先驱作用,集中体现为毛泽东林业建设思想;发展阶段,我国生态文明思想呈现出接续性、连贯性和发展性,具有承上启下的作用;完善阶段,我国生态文明思想体现了对马克思主义思想的灵活运用,对前代探索成果的继承,对于实践经验的高度概括,对于时代发展的创新开拓,形成了习近平新时代生态文明思想体系。在各个阶段的实践中,生态文明建设成效显著,尤其是新时代10年来生态文明建设取得了历史性成就和标志性成果,为世界各国提供了中国智慧和中国方案。

文化传承视域下传统刺绣工艺与现代服装设计的结合

传统刺绣工艺作为一种重要的文化遗产,具有丰富的历史和文化内涵。将传统刺绣工艺融入现代服装设计,能够突出现代服饰的装饰感,改善服装构图,使传统刺绣工艺焕发出新的生机和活力,从而促进传统刺绣工艺的传承和发展。通过分析传统刺绣工艺与现代服装设计的关联性,分析了传统刺绣工艺在现代服装设计中的表达方式,探究了文化传承视域下传统刺绣工艺与现代服装设计结合的策略,以期促进对传统刺绣工艺的保护和传承,以及现代服装样式、造型、风格等的创新。

国医大师熊继柏治疗失眠的方药规律分析

目的对国医大师熊继柏教授治疗失眠的病案进行数据挖掘,分析熊继柏教授诊治失眠的用方、用药经验。方法基于中医传承辅助平台软件(V3.5),归纳和分析熊继柏教授在湖南中医药大学第一附属医院治疗失眠患者的门诊病历数据,利用该平台软件的关联规则、复杂系统熵聚类等统计方法进行数据挖掘和分析,总结药物的性味、归经、应用频次、药对组合及合方,对“证-症-方”“证-症-药”“证-方-药”进行关联,结合熊继柏教授对失眠病因病机、治则治法的认识,明确核心用药,探索其对失眠的诊治规律及遣方用药心得。结果通过总结分析,共纳入病历276份,处方中用药频次较多的有酸枣仁、龙齿、茯神、甘草,重在补虚安神;黄连、陈皮、竹茹、半夏、珍珠母、远志,重在清热化痰安神。用药性味偏甘、苦、辛,归经多为心、脾经。并归纳出虚证治疗常用合方为酸枣仁汤、枕中丹和甘麦大枣汤;因痰所致失眠治疗的主方为温胆汤及温胆汤类方(枣仁温胆汤、黄连温胆汤及十味温胆汤)。结论国医大师熊继柏治疗失眠以“补脾化痰清热,养血补肝宁心”为治疗原则,以温胆汤为基础进行加减化裁。

论习近平文化思想对马克思主义文化理论的继承与发展

习近平文化思想与马克思主义文化理论一脉相承,是马克思主义文化理论的时代表达,实现了对马克思主义文化理论的继承与发展。从马克思主义立场来看,习近平文化思想继承与发展了马克思主义文化理论的唯物主义哲学立场、人民群众政治立场与共产主义价值立场;从马克思主义观点来看,习近平文化思想继承与发展了马克思主义文化理论关于文化认识、文化价值、意识形态文化、民族传统文化与世界文化的观点;从马克思主义方法来看,习近平文化思想继承与发展了马克思主义文化理论的系统分析法、矛盾分析法与唯物辩证法。习近平文化思想内涵丰富、意义重大,开拓了马克思主义文化理论的新境界、开启了中华文化传承与发展的新篇章、开拓了新时代文化强国建设的新征程。