To study the effects of the initiation position on the damage and fracture characteristics of linear-charge blasting, blasting model experiments were conducted in this study using computed tomography scanning and thre...To study the effects of the initiation position on the damage and fracture characteristics of linear-charge blasting, blasting model experiments were conducted in this study using computed tomography scanning and three-dimensional reconstruction methods. The fractal damage theory was used to quantify the crack distribution and damage degree of sandstone specimens after blasting. The results showed that regardless of an inverse or top initiation, due to compression deformation and sliding frictional resistance, the plugging medium of the borehole is effective. The energy of the explosive gas near the top of the borehole is consumed. This affects the effective crushing of rocks near the top of the borehole, where the extent of damage to Sections Ⅰ and Ⅱ is less than that of Sections Ⅲ and Ⅳ. In addition, the analysis revealed that under conditions of top initiation, the reflected tensile damage of the rock at the free face of the top of the borehole and the compression deformation of the plug and friction consume more blasting energy, resulting in lower blasting energy efficiency for top initiation. As a result, the overall damage degree of the specimens in the top-initiation group was significantly smaller than that in the inverse-initiation group. Under conditions of inverse initiation, the blasting energy efficiency is greater, causing the specimen to experience greater damage. Therefore, in the engineering practice of rock tunnel cut blasting, to utilize blasting energy effectively and enhance the effects of rock fragmentation, using the inverse-initiation method is recommended. In addition, in three-dimensional(3D) rock blasting, the bottom of the borehole has obvious end effects under the conditions of inverse initiation, and the crack distribution at the bottom of the borehole is trumpet-shaped. The occurrence of an end effect in the 3D linear-charge blasting model experiment is related to the initiation position and the blocking condition.展开更多
Water freezing in rock fractures causes volumetric expansion and fracture development through frost heaving.This study introduces a novel analytical model to investigate how uneven freezing force and surrounding rock ...Water freezing in rock fractures causes volumetric expansion and fracture development through frost heaving.This study introduces a novel analytical model to investigate how uneven freezing force and surrounding rock pressure influence fracture initiation,based on mass conservation,elasticity,and water-ice phase transition principles.A model for rock fracture initiation considering freezing temperature,uneven freezing expansion,in-situ stress,and lateral pressure was proposed based on fracture mechanics.Equations for stress intensity factors were developed and validated using the phase field method.The effects of rock elastic modulus anisotropy and critical fracture energy density on fracture initiation were also discussed.The results show that the values of KI and KII exhibit an upward trend as the freezing temperature,uneven expansion,in-situ stress,and lateral pressure increase.The uneven freezing expansion has the most significant influence on KI and KII values among these parameters.As the uneven freezing expansion coefficient increases to 0.5,the fracture initiation mode shifts from tensile fracture to shear fracture.As the lateral pressure coefficient increases to 1,the fracture initiation mode shifts from tensile fracture to shear fracture.Rock elastic modulus anisotropy causes fractures to propagate in a clockwise direction,forming a'butterfly'pattern.Critical fracture energy density an isotropy causes counterclockwise deviation in propagation direction,resulting in branching paths and an'H'-shaped pattern.展开更多
Nitrogen(N)and potassium(K)are two key mineral nutrient elements involved in rice growth.Accurate diagnosis of N and K status is very important for the rational application of fertilizers at a specific rice growth sta...Nitrogen(N)and potassium(K)are two key mineral nutrient elements involved in rice growth.Accurate diagnosis of N and K status is very important for the rational application of fertilizers at a specific rice growth stage.Therefore,we propose a hybrid model for diagnosing rice nutrient levels at the early panicle initiation stage(EPIS),which combines a convolutional neural network(CNN)with an attention mechanism and a long short-term memory network(LSTM).The model was validated on a large set of sequential images collected by an unmanned aerial vehicle(UAV)from rice canopies at different growth stages during a two-year experiment.Compared with VGG16,AlexNet,GoogleNet,DenseNet,and inceptionV3,ResNet101 combined with LSTM obtained the highest average accuracy of 83.81%on the dataset of Huanghuazhan(HHZ,an indica cultivar).When tested on the datasets of HHZ and Xiushui 134(XS134,a japonica rice variety)in 2021,the ResNet101-LSTM model enhanced with the squeeze-and-excitation(SE)block achieved the highest accuracies of 85.38 and 88.38%,respectively.Through the cross-dataset method,the average accuracies on the HHZ and XS134 datasets tested in 2022 were 81.25 and 82.50%,respectively,showing a good generalization.Our proposed model works with the dynamic information of different rice growth stages and can efficiently diagnose different rice nutrient status levels at EPIS,which are helpful for making practical decisions regarding rational fertilization treatments at the panicle initiation stage.展开更多
Lily(Lilium spp.) is an important ornamental flower, which is mainly propagated by bulbs. Cell wall invertases(CWINs), which catalyze the irreversibly conversion of sucrose into glucose and fructose in the extracellul...Lily(Lilium spp.) is an important ornamental flower, which is mainly propagated by bulbs. Cell wall invertases(CWINs), which catalyze the irreversibly conversion of sucrose into glucose and fructose in the extracellular space, are key enzymes participating in sucrose allocation in higher plants. Previous studies have shown that CWINs play an essential role in bulblet initiation process in bulbous crops, but the underlying molecular mechanism remains unclear. Here, a CWIN gene of Lilium brownii var. giganteum(Lbg) was identified and amplified from genomic DNA. Quantitative RT-PCR assays revealed that the expression level of LbgCWIN1 was highly upregulated exactly when the endogenous starch degraded in non-sucrose medium during in vitro bulblet initiation in Lbg. Phylogenetic relationship, motif, and domain analysis of LbgCWIN1 protein and CWINs in other plant species showed that all sequences of these CWIN proteins were highly conserved. The promoter sequence of LbgCWIN1 possessed a number of alpha-amylase-, phytohormone-, light-and stress-responsive cis-elements. Meanwhile, β-glucuronidase(GUS) assay showed that the 459 bp upstream fragment from the translational start site displayed maximal promoter activity. These results revealed that LbgCWIN1 might function in the process of in vitro bulblet initiation and be in the response to degradation of endogenous starch.展开更多
2,4-dinitroanisole(DNAN)is a good replacement for 2,4,6-trinitrotoluene(TNT)in melt-cast explosives due to its superior insensitivity.With the increasing use of DNAN-based melt-cast explosives,the prediction of reacti...2,4-dinitroanisole(DNAN)is a good replacement for 2,4,6-trinitrotoluene(TNT)in melt-cast explosives due to its superior insensitivity.With the increasing use of DNAN-based melt-cast explosives,the prediction of reaction violence and hazard assessment of the explosives subjected to shock is of great significance.This study investigated the shock initiation characteristics for a DNAN-based melt-cast explosive,DHFA,using the one-dimensional Lagrangian apparatus.The embedded manganin gauges in the apparatus record the pressure histories at four Lagrangian positions and show that shock-todetonation transition in DHFA needs a high input shock pressure.The experimental data are analyzed to calibrate the Ignition and Growth model.The calibration is performed using an objective function based on both pressure history and the arrival time of shock.Good agreement between experimental and calculated pressure histories indicates the high accuracy of the calibrated parameters with the optimization method.展开更多
This review examines the application of continuous renal replacement therapy(CRRT)in patients with sepsis-associated acute kidney injury(S-AKI),with a particular focus on the timing of CRRT initiation.This review addr...This review examines the application of continuous renal replacement therapy(CRRT)in patients with sepsis-associated acute kidney injury(S-AKI),with a particular focus on the timing of CRRT initiation.This review addresses the controversy surrounding initiation timing and proposes future research directions.Through a systematic review of recent literature on CRRT for S-AKI,working principles,therapeutic mechanisms,initiation timing of CRRT,and related meta-analyses were summarized.Current studies indicate that the optimal timing for CRRT initiation in S-AKI patients remains inconclusive,with ongoing debate regarding whether early initiation significantly improves patient survival and renal function.This lack of consensus reflects the heterogeneity of the S-AKI patient population and the limitations of existing research methodologies.Future studies should focus on advancing the application of precision medicine in S-AKI and developing individualized treatment strategies by integrating multidimensional information to optimize CRRT utilization and improve patient outcomes.展开更多
Introduction: Actors of psychoactive drug initiation refer to those who introduce others to psychoactive drug use (initiators) and those who are introduced to psychoactive drugs (users). By identifying their features,...Introduction: Actors of psychoactive drug initiation refer to those who introduce others to psychoactive drug use (initiators) and those who are introduced to psychoactive drugs (users). By identifying their features, better prevention and intervention programs can be developed to reduce psychoactive drug use among adolescents. This article describes the role of actors of psychoactive drug initiation among teenagers in secondary schools in Yaoundé (Cameroon). Methodology: A cross sectional study was carried out in twelve secondary schools in Yaoundé from October 2022 to May 2023. Adolescents from Form four to upper sixth, who assented to participate in the study and received parental consent were included. Data were collected in a structured self-reported questionnaire and analyzed using SPSS 23. Quantitative variables were expressed using means, standard deviations, median and interquartile ranges depending on the distribution of data. Qualitative variables were expressed in the form of frequency and percentages. Results: Drug use was more prevalent among male adolescents (55.3%) from nuclear families (91.4%) who received relatively high pocket money. The main sources of drug exposure were non-family members (49.7%), especially friends outside school. The most frequent place of initiation was snack bars (33.1%). Conclusion: The study revealed the importance of the family, friends and leisure places in the initiation process of drug use in teenagers. Based on these results, parents and school authorities should work together to create a safe and supportive environment that fosters communication, education to prevent drug abuse among adolescents in Yaoundé.展开更多
The blast-induced ground vibrations can be significantly controlled by varying the location and orien-tation of point of interest from blast site.The blast waves generated due to individual holes get super-imposed and...The blast-induced ground vibrations can be significantly controlled by varying the location and orien-tation of point of interest from blast site.The blast waves generated due to individual holes get super-imposed and resultant peak particle velocity(PPV)generates.With the orientation sequence of holes blasts on site,the superimposition angle of wave changes and hence results in significant variation in resultant PPV.The orientation with respect to the initiation of blasts resulting in lowest PPV needs to be identified for any site.By knowing the PPV contour of vibration waves in mine sites,it is possible to reduce the vibration on the structures by changing the initiation sequence.In this paper,experimental blasts were conducted at two different mine sites and the PPV values were recorded at different ori-entations from the blast site and its initiation sequence.The PPV contours were drawn to identify the orientation with least and highest PPV generation line.It was found that by merely changing the initi-ation sequence of blasts with respect to the sensitive structure or point of interest,the PPV values can be reduced significantly up to 76.9%.展开更多
Recently,Garai et al.(2022)published a paper on the impact of orientation of blast initiation on ground vibrations.However,some of the claims are not supported by the results of the given tests.In Fig.1(see Fig.8 in G...Recently,Garai et al.(2022)published a paper on the impact of orientation of blast initiation on ground vibrations.However,some of the claims are not supported by the results of the given tests.In Fig.1(see Fig.8 in Garai et al.,2022),there are contours of measured vibration velocities in 4 directions(every 90?)and an incorrect interpretation between them.By placing all measured vibration velocity values(Gerai et al.,2022)at well-defined points on a single figure,it was not possible to precisely determine the type of vibration velocity,such as radial,tangential and vertical vibration velocities,with their different shapes.An incorrect conclusion was also drawn about the direction of the highest vibration velocity.The paper by Garai et al.(2022)measured the vibrational velocity of the medium through which the seismic wave passed,but used the incorrect term shock wave.The shock wave would have destroyed the seismic measuring instruments.A superposition of the vibrational velocity was considered,but not combined with the vibrational frequency of the seismic wave.This paper presents a method for selecting the time delay between successively initiated explosive charges to the measured frequency of the seismic wave,so that the direction of initiation of the explosive charges does not affect the vibration velocity of the ground through which the seismic wave passes.The theoretical and measured shapes and waveforms of radial velocity and tangential velocity in an opencast lignite mine are then presented.Moreover,the conditions for the formation of shock wave,transition wave and seismic waves are presented.展开更多
Due to climate change, extreme heat stress events have become more frequent, adversely affecting rice yield and grain quality. The accumulation and translocation of dry matter and nitrogen substances are essential for...Due to climate change, extreme heat stress events have become more frequent, adversely affecting rice yield and grain quality. The accumulation and translocation of dry matter and nitrogen substances are essential for rice yield and grain quality. To assess the impact of high temperature stress(HTS) at the early panicle initiation(EPI) stage on the accumulation, transportation, and distribution of dry matter and nitrogen substances in various organs of rice, as well as the resulting effects on rice yield and grain quality, pot experiments were conducted using an indica rice cultivar Yangdao 6(YD6) and a japonica rice cultivar Jinxiangyu 1(JXY1) under both normal temperature(32 ℃/26 ℃) and high temperature(38 ℃/29 ℃) conditions. The results indicated that exposure to HTS at the EPI stage significantly decreased rice yield by reducing spikelet number per panicle, grain-filling rate, and grain weight. However, it improved the nutritional quality of rice grains by increasing protein and amylose contents. The reduction in nitrogen and dry matter accumulation accounted for the changes in spikelet number per panicle, grain-filling rate, and grain size. Under HTS, the decrease in nitrogen accumulation accompanied by the reduction in dry matter may be due to the down-regulation of leaf net photosynthesis and senescence, as evidenced by the decrease in nitrogen content. Furthermore, the decrease in sink size limited the translocation of dry matter and nitrogen substances to grains, which was closely related to the reduction in grain weight and the deterioration of grain quality. These findings significantly contribute to our understanding of the mechanisms of HTS on grain yield and quality formation from the perspective of dry matter and nitrogen accumulation and translocation. Further efforts are needed to improve the adaptability of rice varieties to climate change in the near future.展开更多
Compression is required for all kinds of subduction initiations,which may cause either subsidence or uplift,depending on the ages of the oceanic plates.Subduction initiations associated with the old oceanic crust tend...Compression is required for all kinds of subduction initiations,which may cause either subsidence or uplift,depending on the ages of the oceanic plates.Subduction initiations associated with the old oceanic crust tend to amplify preexisting subsidence by compression,whereas those associated with young oceanic plates may result in uplift.展开更多
At the beginning of the Cenozoic,the atmospheric CO_(2)concentration increased rapidly from~2000 ppmv at 60 Ma to~4600 ppmv at 51 Ma,which is 5–10 times higher than the present value,and then continuous declined from...At the beginning of the Cenozoic,the atmospheric CO_(2)concentration increased rapidly from~2000 ppmv at 60 Ma to~4600 ppmv at 51 Ma,which is 5–10 times higher than the present value,and then continuous declined from~51 to 34 Ma.The cause of this phenomenon is still not well understood.In this study,we demonstrate that the initiation of Cenozoic west Pacific plate subduction,triggered by the hard collision in the Tibetan Plateau,occurred at approximately 51 Ma,coinciding with the tipping point.The water depths of the Pacific subduction zones are mostly below the carbonate compensation depths,while those of the Neo-Tethys were much shallower before the collision and caused far more carbonate subducting.Additionally,more volcanic ashes erupted from the west Pacific subduction zones,which consume CO_(2).The average annual west Pacific volvano eruption is 1.11 km~3,which is higher than previous estimations.The amount of annual CO_(2)absorbed by chemical weathering of additional west Pacific volcanic ashes could be comparable to the silicate weathering by the global river.We propose that the initiation of the western Pacific subduction controlled the long-term reduction of atmospheric CO_(2)concentration.展开更多
High temperatures cause physiological and biochemical changes and significantly affect young panicle development of rice(Oryza sativa L.).Brassinosteroids play important roles in enhancing crop stress resistance.In th...High temperatures cause physiological and biochemical changes and significantly affect young panicle development of rice(Oryza sativa L.).Brassinosteroids play important roles in enhancing crop stress resistance.In this study,we subjected rice cultivars Huanghuazhan(heat-resistant)and IR36(heat-sensitive)to high temperature(HT,40 oC)or normal temperature(NT,33 oC)for 7 d at the panicle initiation stage,in conjunction with application of 24-epibrassinolide[EBR,a synthetic brassinolide(BR)]or brassinazole(BRZ,a BR biosynthesis inhibitor)at the beginning of the treatments.HT exacerbated spikelet degeneration and inhibited young panicle growth,which were partially prevented by EBR application,while BRZ application aggravated the reduction in spikelet number.HT decreased the contents of BR,active cytokinins(aCTK),active gibberellins(aGA)and indole-3-acetic acid(IAA),but increased the content of abscisic acid(ABA)in young panicles.The activities of key enzymes involved in sucrose hydrolysis,glycolysis and the tricarboxylic acid cycle in young panicles were decreased with the change of endogenous hormone levels under HT.In addition,the contents of H2O2 and malondialdehyde(MDA)were increased and the activities of antioxidant enzymes were decreased in young panicles.Exogenous application of EBR induced the expression of phytohormone biosynthesis-related genes and down-regulated the expression of phytohormone catabolism-related genes to increase the contents of endogenous BR,aCTK,aGA and ABA,thus promoting the decomposition and utilization of sucrose in young panicles,enhancing the activities of superoxide dismutase,catalase and peroxidase,and reducing the accumulation of H2O2 and MDA in young panicles,whereas application of BRZ had the opposite physiological effects.These results showed that brassinosteroids mediate endogenous phytohormone metabolism to alleviate HT injury at the panicle initiation stage in rice.展开更多
The detonation wave-aiming warhead can effectively enhance the lethality efficiency. In the past, rules for casing rupture and velocity distribution under asymmetrical initiations were not adequately investigated. In ...The detonation wave-aiming warhead can effectively enhance the lethality efficiency. In the past, rules for casing rupture and velocity distribution under asymmetrical initiations were not adequately investigated. In this study, X-ray photography and numerical modelling are used to examine the casing expansions under centre point, asymmetrical one-point, and asymmetrical two-point(with central angles of 45° and 90°) initiations. The results indicate that early casing ruptures are caused by local high pressures, induced by the initiation, detonation wave interaction, and Mach wave onset. The fragment shapes are controlled by the impact angle of the detonation wave. The fragment velocity distributions differ under different initiation types, and the end rarefaction waves can affect the velocity distribution.This study can serve as a reference for the design and optimization of high-efficiency warheads.展开更多
Accurately predicting reactive flow is a challenge when characterizing an explosive under external shock stimuli as the shock initiation time is on the order of a microsecond.The present study constructs a new Ignitio...Accurately predicting reactive flow is a challenge when characterizing an explosive under external shock stimuli as the shock initiation time is on the order of a microsecond.The present study constructs a new Ignition-Growth reaction rate model,which can describe the shock initiation processes of explosives with different initial densities,particle sizes and loading pressures by only one set of model parameters.Compared with the Lee-Tarver reaction rate model,the new Ignition-Growth reaction rate model describes better the shock initiation process of explosives and requires fewer model parameters.Moreover,the shock initiation of a 2,4-Dinitroanisole(DNAN)-based melt-cast explosive RDA-2(DNAN/HMX(octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazoncine)/aluminum)are investigated both experimentally and numerically.A series of shock initiation experiments is performed with manganin piezoresistive pressure gauges and corresponding numerical simulations are carried out with the new Ignition-Growth reaction rate model.The RDA-2 explosive is found to have higher critical initiation pressure and lower shock sensitivity than traditional explosives(such as the Comp.B explosive).The calibrated reaction rate model parameters of RDA-2 could provide numerical basis for its further application.展开更多
The prediction of wheel/rail rolling contact fatigue(RCF)crack initiation during railway operations is an important task.Since RCF crack evolution is influenced by many factors,its prediction process is complex.This p...The prediction of wheel/rail rolling contact fatigue(RCF)crack initiation during railway operations is an important task.Since RCF crack evolution is influenced by many factors,its prediction process is complex.This paper reviews the existing approaches to predict RCF crack initiation.The crack initiation region is predicted by the shakedown map.By combining the shakedown map with various initiation criteria and the critical plane method,the crack initiation life is calculated.The classification,methodologies,theories and applications of these approaches are included in this paper.The advantages and limitations of these methods are analyzed to provide recommendation for RCF crack initiation prediction.This review highlights that wheel/rail dynamic characteristic,complex working conditions,surface defects and wear all affect the RCF crack initiation.The optimal selection of criteria is essential in the crack initiation prediction.Based on the research gap regarding the challenging process of crack initiation prediction detailed in this review,a proposed prediction process of RCF crack initiation is proposed to achieve a more accurate result.展开更多
The fatigue crack initiation and early propagation behavior of 2A97 Al-Li alloy was studied. The smooth specimens were fatigued at room temperature under constant maximum stress control when stress ratio (R) is 0.1 ...The fatigue crack initiation and early propagation behavior of 2A97 Al-Li alloy was studied. The smooth specimens were fatigued at room temperature under constant maximum stress control when stress ratio (R) is 0.1 and frequency (f) is 40 Hz. Microstructure observations were examined by optical microscopy, transmission electron microscopy, scanning electron microscopy and electron back scattered diffusion, in order to investigate the relationship between microstructure and fatigue crack initiation and early propagation behavior of 2A97 alloy. The results show that the fatigue cracks are predominantly initiated at inclusions and coarsen secondary phases on the surface of 2A97 alloy. The fatigue crack early propagation behavior of 2A97 alloy is predominantly influenced by the interactions between grain structure and dislocations or persistent slip bands (PSBs). When the misorientation of two neighbouring grains is close to the orientations of the favorable slip plane within these two grains, high-angle grain boundary severely hinders the PSBs passing through, and thus leads to crack bifurcation and deflection.展开更多
The time course of the initiation of different types of apical primordia on the stem of wheat (Triticum aestivum L.) was investigated to establish a comprehensive pattern of apical primordium development and quantitat...The time course of the initiation of different types of apical primordia on the stem of wheat (Triticum aestivum L.) was investigated to establish a comprehensive pattern of apical primordium development and quantitative dynamic relationships among different primordium initiation. The results showed that the initiation of leaf and bracteal primordia took the S shape, and that of spikelet and floret took the rise stage of parabolic shape in relation to GDD (growing degree days after sowing) in wheat. The bracteal was much like vegetative rather than reproductive organ in terms of the dynamic pattern of primordium initiation. The progress of spikelet and floret primordium initiation could well reflect the characteristics of different genotypes and the impact of different ecological environments on wheat apical development. The integrated model of different primordium initiation in shoot of wheat was an S_shaped curvilinear, and could be divided into three sub_models. The number of leaf primordia was affected by both genotype and environment, while the numbers of bracteal, spikelet and floret primordia were affected mainly by environmental factors. Measured with mean thermochron, the rates of initiation of leaf, bracteal and spikelet primordia in normal planting were the highest among all the sowing date treatments. In contrast to the relationships among leaf, bracteal, spikelet and their initiation duration, the correlation between the number of floret and its initiation duration was highly significant.展开更多
The ratio of crack initiation stress to the uniaxial compressive strength(SCI,B/SUC,B) and the ratio of axial strain at the crack initiation stress to the axial strain at the uniaxial compressive strength(B,UCB,CI,A,A...The ratio of crack initiation stress to the uniaxial compressive strength(SCI,B/SUC,B) and the ratio of axial strain at the crack initiation stress to the axial strain at the uniaxial compressive strength(B,UCB,CI,A,A/SSSS) were studied by performing numerical stress analysis on blocks having multi flaws at close spacing's under uniaxial loading using PFC3 D. The following findings are obtained: SCI,B/SUC,B has an average value of about 0.5 with a variability of ± 0.1. This range agrees quite well with the values obtained by former research. For joint inclination angle, β=90°,B,UCB,CI,A,A/SSSS is found to be around 0.48 irrespective of the value of joint continuity factor, k. No particular relation is found betweenB,UCB,CI,A,A/SSSS and β; however, the average B,UCB,CI,A,A/SSSS seems to slightly decrease with increasing k. The variability ofB,UCB,CI,A,A/SSSS is found to increase with k.Based on the cases studied in this work,B,UCB,CI,A,A/SSSS ranges between 0.3 and 0.5. This range is quite close to the range of 0.4to 0.6 obtained for SCI,B/SUC,B. The highest variability of ± 0.12 forB,UCB,CI,A,A/SSSS is obtained for k=0.8. For the remaining k values the variability ofB,UCB,CI,A,A/SSSS can be expressed within ± 0.05. This finding is very similar to the finding obtained for the variability of SCI,B/SUC,B.展开更多
In order to study the relationship between charge size and thermal initiation critical temperature of explosive in defined conditions,cook-off test about JH explosive was carried out at a heating rate of 1 ℃/min usin...In order to study the relationship between charge size and thermal initiation critical temperature of explosive in defined conditions,cook-off test about JH explosive was carried out at a heating rate of 1 ℃/min using self-designed cook-off experiment setup based on thermostatic control technology.Numerical simulation was conducted to study the effects of different charge sizes on thermal initiation critical temperature of explosives with FLUENT software.Experiment results show that there is a thermal initiation critical temperature in cook-off bomb.Simulation results show that when the ratio of the length to diameter of explosives grains is a fixed value,the thermal initiation critical temperature of explosives decreases with the increase of the diameter of explosives grains.When the grains diameter of explosives increase up to a certain value,the influence of charge size on thermal initiation critical temperature tends to be weakened.Charge size has no influence on the ignition point of explosives.The ignition point is always in the center of the grain.展开更多
基金supported by the National Natural Science Foundation of China (No.52204085)the Interdisciplinary Research Project for Young Teachers of USTB,Fundamental Research Funds for the Central Universities (No.FRF-IDRY-21-006).
文摘To study the effects of the initiation position on the damage and fracture characteristics of linear-charge blasting, blasting model experiments were conducted in this study using computed tomography scanning and three-dimensional reconstruction methods. The fractal damage theory was used to quantify the crack distribution and damage degree of sandstone specimens after blasting. The results showed that regardless of an inverse or top initiation, due to compression deformation and sliding frictional resistance, the plugging medium of the borehole is effective. The energy of the explosive gas near the top of the borehole is consumed. This affects the effective crushing of rocks near the top of the borehole, where the extent of damage to Sections Ⅰ and Ⅱ is less than that of Sections Ⅲ and Ⅳ. In addition, the analysis revealed that under conditions of top initiation, the reflected tensile damage of the rock at the free face of the top of the borehole and the compression deformation of the plug and friction consume more blasting energy, resulting in lower blasting energy efficiency for top initiation. As a result, the overall damage degree of the specimens in the top-initiation group was significantly smaller than that in the inverse-initiation group. Under conditions of inverse initiation, the blasting energy efficiency is greater, causing the specimen to experience greater damage. Therefore, in the engineering practice of rock tunnel cut blasting, to utilize blasting energy effectively and enhance the effects of rock fragmentation, using the inverse-initiation method is recommended. In addition, in three-dimensional(3D) rock blasting, the bottom of the borehole has obvious end effects under the conditions of inverse initiation, and the crack distribution at the bottom of the borehole is trumpet-shaped. The occurrence of an end effect in the 3D linear-charge blasting model experiment is related to the initiation position and the blocking condition.
基金This study was funded by the National Natural Science Foundation of China(No.51978039).
文摘Water freezing in rock fractures causes volumetric expansion and fracture development through frost heaving.This study introduces a novel analytical model to investigate how uneven freezing force and surrounding rock pressure influence fracture initiation,based on mass conservation,elasticity,and water-ice phase transition principles.A model for rock fracture initiation considering freezing temperature,uneven freezing expansion,in-situ stress,and lateral pressure was proposed based on fracture mechanics.Equations for stress intensity factors were developed and validated using the phase field method.The effects of rock elastic modulus anisotropy and critical fracture energy density on fracture initiation were also discussed.The results show that the values of KI and KII exhibit an upward trend as the freezing temperature,uneven expansion,in-situ stress,and lateral pressure increase.The uneven freezing expansion has the most significant influence on KI and KII values among these parameters.As the uneven freezing expansion coefficient increases to 0.5,the fracture initiation mode shifts from tensile fracture to shear fracture.As the lateral pressure coefficient increases to 1,the fracture initiation mode shifts from tensile fracture to shear fracture.Rock elastic modulus anisotropy causes fractures to propagate in a clockwise direction,forming a'butterfly'pattern.Critical fracture energy density an isotropy causes counterclockwise deviation in propagation direction,resulting in branching paths and an'H'-shaped pattern.
基金supported by the National Key Research and Development Program of China(2022YFD2300700)the Open Project Program of State Key Laboratory of Rice Biology,China National Rice Research Institute(20210403)the Zhejiang“Ten Thousand Talents”Plan Science and Technology Innovation Leading Talent Project,China(2020R52035)。
文摘Nitrogen(N)and potassium(K)are two key mineral nutrient elements involved in rice growth.Accurate diagnosis of N and K status is very important for the rational application of fertilizers at a specific rice growth stage.Therefore,we propose a hybrid model for diagnosing rice nutrient levels at the early panicle initiation stage(EPIS),which combines a convolutional neural network(CNN)with an attention mechanism and a long short-term memory network(LSTM).The model was validated on a large set of sequential images collected by an unmanned aerial vehicle(UAV)from rice canopies at different growth stages during a two-year experiment.Compared with VGG16,AlexNet,GoogleNet,DenseNet,and inceptionV3,ResNet101 combined with LSTM obtained the highest average accuracy of 83.81%on the dataset of Huanghuazhan(HHZ,an indica cultivar).When tested on the datasets of HHZ and Xiushui 134(XS134,a japonica rice variety)in 2021,the ResNet101-LSTM model enhanced with the squeeze-and-excitation(SE)block achieved the highest accuracies of 85.38 and 88.38%,respectively.Through the cross-dataset method,the average accuracies on the HHZ and XS134 datasets tested in 2022 were 81.25 and 82.50%,respectively,showing a good generalization.Our proposed model works with the dynamic information of different rice growth stages and can efficiently diagnose different rice nutrient status levels at EPIS,which are helpful for making practical decisions regarding rational fertilization treatments at the panicle initiation stage.
基金financially supported by the National Natural Science Foundation of China (Grant Nos.32101571,32002071)the Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding (Grant No.2021C02071-6)。
文摘Lily(Lilium spp.) is an important ornamental flower, which is mainly propagated by bulbs. Cell wall invertases(CWINs), which catalyze the irreversibly conversion of sucrose into glucose and fructose in the extracellular space, are key enzymes participating in sucrose allocation in higher plants. Previous studies have shown that CWINs play an essential role in bulblet initiation process in bulbous crops, but the underlying molecular mechanism remains unclear. Here, a CWIN gene of Lilium brownii var. giganteum(Lbg) was identified and amplified from genomic DNA. Quantitative RT-PCR assays revealed that the expression level of LbgCWIN1 was highly upregulated exactly when the endogenous starch degraded in non-sucrose medium during in vitro bulblet initiation in Lbg. Phylogenetic relationship, motif, and domain analysis of LbgCWIN1 protein and CWINs in other plant species showed that all sequences of these CWIN proteins were highly conserved. The promoter sequence of LbgCWIN1 possessed a number of alpha-amylase-, phytohormone-, light-and stress-responsive cis-elements. Meanwhile, β-glucuronidase(GUS) assay showed that the 459 bp upstream fragment from the translational start site displayed maximal promoter activity. These results revealed that LbgCWIN1 might function in the process of in vitro bulblet initiation and be in the response to degradation of endogenous starch.
基金Scientific Research Foundation for High-level Talents of Anhui University of Science and Technology(Grant No.2021yjrc38)Anhui Provincial Natural Science Foundation(Grant No.2208085QA27)+1 种基金National Natural Science Foundation of China(Grant Nos.11972046,12002266)the authors would like to thank these foundations for financial support.
文摘2,4-dinitroanisole(DNAN)is a good replacement for 2,4,6-trinitrotoluene(TNT)in melt-cast explosives due to its superior insensitivity.With the increasing use of DNAN-based melt-cast explosives,the prediction of reaction violence and hazard assessment of the explosives subjected to shock is of great significance.This study investigated the shock initiation characteristics for a DNAN-based melt-cast explosive,DHFA,using the one-dimensional Lagrangian apparatus.The embedded manganin gauges in the apparatus record the pressure histories at four Lagrangian positions and show that shock-todetonation transition in DHFA needs a high input shock pressure.The experimental data are analyzed to calibrate the Ignition and Growth model.The calibration is performed using an objective function based on both pressure history and the arrival time of shock.Good agreement between experimental and calculated pressure histories indicates the high accuracy of the calibrated parameters with the optimization method.
基金Wenzhou Science and Technology Project(Grant No.Y2020536)。
文摘This review examines the application of continuous renal replacement therapy(CRRT)in patients with sepsis-associated acute kidney injury(S-AKI),with a particular focus on the timing of CRRT initiation.This review addresses the controversy surrounding initiation timing and proposes future research directions.Through a systematic review of recent literature on CRRT for S-AKI,working principles,therapeutic mechanisms,initiation timing of CRRT,and related meta-analyses were summarized.Current studies indicate that the optimal timing for CRRT initiation in S-AKI patients remains inconclusive,with ongoing debate regarding whether early initiation significantly improves patient survival and renal function.This lack of consensus reflects the heterogeneity of the S-AKI patient population and the limitations of existing research methodologies.Future studies should focus on advancing the application of precision medicine in S-AKI and developing individualized treatment strategies by integrating multidimensional information to optimize CRRT utilization and improve patient outcomes.
文摘Introduction: Actors of psychoactive drug initiation refer to those who introduce others to psychoactive drug use (initiators) and those who are introduced to psychoactive drugs (users). By identifying their features, better prevention and intervention programs can be developed to reduce psychoactive drug use among adolescents. This article describes the role of actors of psychoactive drug initiation among teenagers in secondary schools in Yaoundé (Cameroon). Methodology: A cross sectional study was carried out in twelve secondary schools in Yaoundé from October 2022 to May 2023. Adolescents from Form four to upper sixth, who assented to participate in the study and received parental consent were included. Data were collected in a structured self-reported questionnaire and analyzed using SPSS 23. Quantitative variables were expressed using means, standard deviations, median and interquartile ranges depending on the distribution of data. Qualitative variables were expressed in the form of frequency and percentages. Results: Drug use was more prevalent among male adolescents (55.3%) from nuclear families (91.4%) who received relatively high pocket money. The main sources of drug exposure were non-family members (49.7%), especially friends outside school. The most frequent place of initiation was snack bars (33.1%). Conclusion: The study revealed the importance of the family, friends and leisure places in the initiation process of drug use in teenagers. Based on these results, parents and school authorities should work together to create a safe and supportive environment that fosters communication, education to prevent drug abuse among adolescents in Yaoundé.
文摘The blast-induced ground vibrations can be significantly controlled by varying the location and orien-tation of point of interest from blast site.The blast waves generated due to individual holes get super-imposed and resultant peak particle velocity(PPV)generates.With the orientation sequence of holes blasts on site,the superimposition angle of wave changes and hence results in significant variation in resultant PPV.The orientation with respect to the initiation of blasts resulting in lowest PPV needs to be identified for any site.By knowing the PPV contour of vibration waves in mine sites,it is possible to reduce the vibration on the structures by changing the initiation sequence.In this paper,experimental blasts were conducted at two different mine sites and the PPV values were recorded at different ori-entations from the blast site and its initiation sequence.The PPV contours were drawn to identify the orientation with least and highest PPV generation line.It was found that by merely changing the initi-ation sequence of blasts with respect to the sensitive structure or point of interest,the PPV values can be reduced significantly up to 76.9%.
文摘Recently,Garai et al.(2022)published a paper on the impact of orientation of blast initiation on ground vibrations.However,some of the claims are not supported by the results of the given tests.In Fig.1(see Fig.8 in Garai et al.,2022),there are contours of measured vibration velocities in 4 directions(every 90?)and an incorrect interpretation between them.By placing all measured vibration velocity values(Gerai et al.,2022)at well-defined points on a single figure,it was not possible to precisely determine the type of vibration velocity,such as radial,tangential and vertical vibration velocities,with their different shapes.An incorrect conclusion was also drawn about the direction of the highest vibration velocity.The paper by Garai et al.(2022)measured the vibrational velocity of the medium through which the seismic wave passed,but used the incorrect term shock wave.The shock wave would have destroyed the seismic measuring instruments.A superposition of the vibrational velocity was considered,but not combined with the vibrational frequency of the seismic wave.This paper presents a method for selecting the time delay between successively initiated explosive charges to the measured frequency of the seismic wave,so that the direction of initiation of the explosive charges does not affect the vibration velocity of the ground through which the seismic wave passes.The theoretical and measured shapes and waveforms of radial velocity and tangential velocity in an opencast lignite mine are then presented.Moreover,the conditions for the formation of shock wave,transition wave and seismic waves are presented.
基金supported by the Jiangsu Agriculture Science and Technology Innovation Fund,China(Grant No.CX(23)1035)the National Natural Science Foundation of China(Grant Nos.32201888,32071943,and 32272197)+2 种基金the Provincial Natural Science Foundation of Jiangsu,China(Grant No.BK20200923)the National Key Research and Development Program of China(Grant Nos.SQ 2022YFD1500402 and SQ2022YFD2300304)the Priority Academic Program Development of Jiangsu Higher Education Institutions,China.
文摘Due to climate change, extreme heat stress events have become more frequent, adversely affecting rice yield and grain quality. The accumulation and translocation of dry matter and nitrogen substances are essential for rice yield and grain quality. To assess the impact of high temperature stress(HTS) at the early panicle initiation(EPI) stage on the accumulation, transportation, and distribution of dry matter and nitrogen substances in various organs of rice, as well as the resulting effects on rice yield and grain quality, pot experiments were conducted using an indica rice cultivar Yangdao 6(YD6) and a japonica rice cultivar Jinxiangyu 1(JXY1) under both normal temperature(32 ℃/26 ℃) and high temperature(38 ℃/29 ℃) conditions. The results indicated that exposure to HTS at the EPI stage significantly decreased rice yield by reducing spikelet number per panicle, grain-filling rate, and grain weight. However, it improved the nutritional quality of rice grains by increasing protein and amylose contents. The reduction in nitrogen and dry matter accumulation accounted for the changes in spikelet number per panicle, grain-filling rate, and grain size. Under HTS, the decrease in nitrogen accumulation accompanied by the reduction in dry matter may be due to the down-regulation of leaf net photosynthesis and senescence, as evidenced by the decrease in nitrogen content. Furthermore, the decrease in sink size limited the translocation of dry matter and nitrogen substances to grains, which was closely related to the reduction in grain weight and the deterioration of grain quality. These findings significantly contribute to our understanding of the mechanisms of HTS on grain yield and quality formation from the perspective of dry matter and nitrogen accumulation and translocation. Further efforts are needed to improve the adaptability of rice varieties to climate change in the near future.
基金Supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Nos.XDA22050103,XDB42020203)。
文摘Compression is required for all kinds of subduction initiations,which may cause either subsidence or uplift,depending on the ages of the oceanic plates.Subduction initiations associated with the old oceanic crust tend to amplify preexisting subsidence by compression,whereas those associated with young oceanic plates may result in uplift.
基金supported by NSFC Major Research Plan on‘‘West-Pacific Earth System Multispheric Interactions’’to Prof.Weidong Sun(Grant No.92258303)AND Prof.Tianyu Chen(Grant No.91858105)。
文摘At the beginning of the Cenozoic,the atmospheric CO_(2)concentration increased rapidly from~2000 ppmv at 60 Ma to~4600 ppmv at 51 Ma,which is 5–10 times higher than the present value,and then continuous declined from~51 to 34 Ma.The cause of this phenomenon is still not well understood.In this study,we demonstrate that the initiation of Cenozoic west Pacific plate subduction,triggered by the hard collision in the Tibetan Plateau,occurred at approximately 51 Ma,coinciding with the tipping point.The water depths of the Pacific subduction zones are mostly below the carbonate compensation depths,while those of the Neo-Tethys were much shallower before the collision and caused far more carbonate subducting.Additionally,more volcanic ashes erupted from the west Pacific subduction zones,which consume CO_(2).The average annual west Pacific volvano eruption is 1.11 km~3,which is higher than previous estimations.The amount of annual CO_(2)absorbed by chemical weathering of additional west Pacific volcanic ashes could be comparable to the silicate weathering by the global river.We propose that the initiation of the western Pacific subduction controlled the long-term reduction of atmospheric CO_(2)concentration.
基金funded by the Natural Science Foundation of Zhejiang Province,China(Grant No.LQ20C130009)the Science and Technology Project of Zhejiang Province,China(Grant No.2022C02034)the Special Fund for China Agricultural Research System(Grant No.CARS-01-22)。
文摘High temperatures cause physiological and biochemical changes and significantly affect young panicle development of rice(Oryza sativa L.).Brassinosteroids play important roles in enhancing crop stress resistance.In this study,we subjected rice cultivars Huanghuazhan(heat-resistant)and IR36(heat-sensitive)to high temperature(HT,40 oC)or normal temperature(NT,33 oC)for 7 d at the panicle initiation stage,in conjunction with application of 24-epibrassinolide[EBR,a synthetic brassinolide(BR)]or brassinazole(BRZ,a BR biosynthesis inhibitor)at the beginning of the treatments.HT exacerbated spikelet degeneration and inhibited young panicle growth,which were partially prevented by EBR application,while BRZ application aggravated the reduction in spikelet number.HT decreased the contents of BR,active cytokinins(aCTK),active gibberellins(aGA)and indole-3-acetic acid(IAA),but increased the content of abscisic acid(ABA)in young panicles.The activities of key enzymes involved in sucrose hydrolysis,glycolysis and the tricarboxylic acid cycle in young panicles were decreased with the change of endogenous hormone levels under HT.In addition,the contents of H2O2 and malondialdehyde(MDA)were increased and the activities of antioxidant enzymes were decreased in young panicles.Exogenous application of EBR induced the expression of phytohormone biosynthesis-related genes and down-regulated the expression of phytohormone catabolism-related genes to increase the contents of endogenous BR,aCTK,aGA and ABA,thus promoting the decomposition and utilization of sucrose in young panicles,enhancing the activities of superoxide dismutase,catalase and peroxidase,and reducing the accumulation of H2O2 and MDA in young panicles,whereas application of BRZ had the opposite physiological effects.These results showed that brassinosteroids mediate endogenous phytohormone metabolism to alleviate HT injury at the panicle initiation stage in rice.
基金funded by the National Natural Science Foundation of China [Grant No. 12002178]opening project of the State Key Laboratory of Explosion Science and Technology (Beijing Institute of Technology) [Grant No. KFJJ22-17M]the Fundamental Research Funds for Central Universities
文摘The detonation wave-aiming warhead can effectively enhance the lethality efficiency. In the past, rules for casing rupture and velocity distribution under asymmetrical initiations were not adequately investigated. In this study, X-ray photography and numerical modelling are used to examine the casing expansions under centre point, asymmetrical one-point, and asymmetrical two-point(with central angles of 45° and 90°) initiations. The results indicate that early casing ruptures are caused by local high pressures, induced by the initiation, detonation wave interaction, and Mach wave onset. The fragment shapes are controlled by the impact angle of the detonation wave. The fragment velocity distributions differ under different initiation types, and the end rarefaction waves can affect the velocity distribution.This study can serve as a reference for the design and optimization of high-efficiency warheads.
基金supported by the Innovative Group of Material and Structure Impact Dynamics(Grant No.11521062)。
文摘Accurately predicting reactive flow is a challenge when characterizing an explosive under external shock stimuli as the shock initiation time is on the order of a microsecond.The present study constructs a new Ignition-Growth reaction rate model,which can describe the shock initiation processes of explosives with different initial densities,particle sizes and loading pressures by only one set of model parameters.Compared with the Lee-Tarver reaction rate model,the new Ignition-Growth reaction rate model describes better the shock initiation process of explosives and requires fewer model parameters.Moreover,the shock initiation of a 2,4-Dinitroanisole(DNAN)-based melt-cast explosive RDA-2(DNAN/HMX(octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazoncine)/aluminum)are investigated both experimentally and numerically.A series of shock initiation experiments is performed with manganin piezoresistive pressure gauges and corresponding numerical simulations are carried out with the new Ignition-Growth reaction rate model.The RDA-2 explosive is found to have higher critical initiation pressure and lower shock sensitivity than traditional explosives(such as the Comp.B explosive).The calibrated reaction rate model parameters of RDA-2 could provide numerical basis for its further application.
基金supported by National Natural Science Foundation of China(Nos.52202510,U21A20167,52272443 and 51975489)Autonomous Research Project of State Key Laboratory(Nos.2020TPL-T10 and 2022TPL-T04)+1 种基金For a scholarship to S.Y.Zhang,under the State Scholarship Fund of the China Scholarship Council(CSC)(No.202007000128)to pursue study in the Central Queensland University as a cotutelle PhD Student.Dr.Qing Wu is the recipient of an Australian Research Council Discovery Early Career Award(Project Number DE210100273)funded by the Australian Government.
文摘The prediction of wheel/rail rolling contact fatigue(RCF)crack initiation during railway operations is an important task.Since RCF crack evolution is influenced by many factors,its prediction process is complex.This paper reviews the existing approaches to predict RCF crack initiation.The crack initiation region is predicted by the shakedown map.By combining the shakedown map with various initiation criteria and the critical plane method,the crack initiation life is calculated.The classification,methodologies,theories and applications of these approaches are included in this paper.The advantages and limitations of these methods are analyzed to provide recommendation for RCF crack initiation prediction.This review highlights that wheel/rail dynamic characteristic,complex working conditions,surface defects and wear all affect the RCF crack initiation.The optimal selection of criteria is essential in the crack initiation prediction.Based on the research gap regarding the challenging process of crack initiation prediction detailed in this review,a proposed prediction process of RCF crack initiation is proposed to achieve a more accurate result.
文摘The fatigue crack initiation and early propagation behavior of 2A97 Al-Li alloy was studied. The smooth specimens were fatigued at room temperature under constant maximum stress control when stress ratio (R) is 0.1 and frequency (f) is 40 Hz. Microstructure observations were examined by optical microscopy, transmission electron microscopy, scanning electron microscopy and electron back scattered diffusion, in order to investigate the relationship between microstructure and fatigue crack initiation and early propagation behavior of 2A97 alloy. The results show that the fatigue cracks are predominantly initiated at inclusions and coarsen secondary phases on the surface of 2A97 alloy. The fatigue crack early propagation behavior of 2A97 alloy is predominantly influenced by the interactions between grain structure and dislocations or persistent slip bands (PSBs). When the misorientation of two neighbouring grains is close to the orientations of the favorable slip plane within these two grains, high-angle grain boundary severely hinders the PSBs passing through, and thus leads to crack bifurcation and deflection.
文摘The time course of the initiation of different types of apical primordia on the stem of wheat (Triticum aestivum L.) was investigated to establish a comprehensive pattern of apical primordium development and quantitative dynamic relationships among different primordium initiation. The results showed that the initiation of leaf and bracteal primordia took the S shape, and that of spikelet and floret took the rise stage of parabolic shape in relation to GDD (growing degree days after sowing) in wheat. The bracteal was much like vegetative rather than reproductive organ in terms of the dynamic pattern of primordium initiation. The progress of spikelet and floret primordium initiation could well reflect the characteristics of different genotypes and the impact of different ecological environments on wheat apical development. The integrated model of different primordium initiation in shoot of wheat was an S_shaped curvilinear, and could be divided into three sub_models. The number of leaf primordia was affected by both genotype and environment, while the numbers of bracteal, spikelet and floret primordia were affected mainly by environmental factors. Measured with mean thermochron, the rates of initiation of leaf, bracteal and spikelet primordia in normal planting were the highest among all the sowing date treatments. In contrast to the relationships among leaf, bracteal, spikelet and their initiation duration, the correlation between the number of floret and its initiation duration was highly significant.
基金Project(11102224)supported by the National Natural Science Foundation of ChinaProject(201206370124)supported by the China Scholarship Council,China
文摘The ratio of crack initiation stress to the uniaxial compressive strength(SCI,B/SUC,B) and the ratio of axial strain at the crack initiation stress to the axial strain at the uniaxial compressive strength(B,UCB,CI,A,A/SSSS) were studied by performing numerical stress analysis on blocks having multi flaws at close spacing's under uniaxial loading using PFC3 D. The following findings are obtained: SCI,B/SUC,B has an average value of about 0.5 with a variability of ± 0.1. This range agrees quite well with the values obtained by former research. For joint inclination angle, β=90°,B,UCB,CI,A,A/SSSS is found to be around 0.48 irrespective of the value of joint continuity factor, k. No particular relation is found betweenB,UCB,CI,A,A/SSSS and β; however, the average B,UCB,CI,A,A/SSSS seems to slightly decrease with increasing k. The variability ofB,UCB,CI,A,A/SSSS is found to increase with k.Based on the cases studied in this work,B,UCB,CI,A,A/SSSS ranges between 0.3 and 0.5. This range is quite close to the range of 0.4to 0.6 obtained for SCI,B/SUC,B. The highest variability of ± 0.12 forB,UCB,CI,A,A/SSSS is obtained for k=0.8. For the remaining k values the variability ofB,UCB,CI,A,A/SSSS can be expressed within ± 0.05. This finding is very similar to the finding obtained for the variability of SCI,B/SUC,B.
文摘In order to study the relationship between charge size and thermal initiation critical temperature of explosive in defined conditions,cook-off test about JH explosive was carried out at a heating rate of 1 ℃/min using self-designed cook-off experiment setup based on thermostatic control technology.Numerical simulation was conducted to study the effects of different charge sizes on thermal initiation critical temperature of explosives with FLUENT software.Experiment results show that there is a thermal initiation critical temperature in cook-off bomb.Simulation results show that when the ratio of the length to diameter of explosives grains is a fixed value,the thermal initiation critical temperature of explosives decreases with the increase of the diameter of explosives grains.When the grains diameter of explosives increase up to a certain value,the influence of charge size on thermal initiation critical temperature tends to be weakened.Charge size has no influence on the ignition point of explosives.The ignition point is always in the center of the grain.