BACKGROUND Attention-deficit/hyperactivity disorder(ADHD)is one of the most common disorders in child and adolescent psychiatry,with a prevalence of more than 5%.Despite extensive research on ADHD in the last 10 to 20...BACKGROUND Attention-deficit/hyperactivity disorder(ADHD)is one of the most common disorders in child and adolescent psychiatry,with a prevalence of more than 5%.Despite extensive research on ADHD in the last 10 to 20 years,effective treatments are still lacking.Instead,the concept of ADHD seems to have become broader and more heterogeneous.Therefore,the diagnosis and treatment of ADHD remains challenging for clinicians.AIM To investigate the effects of a multimodal integrated intervention for children with ADHD.METHODS Between March 2019 and September 2020,a total of 100 children with ADHD who were diagnosed and treated at our hospital were assessed for eligibility,two of whom revoked their consent.A case-control study was conducted in which the children were equally assigned,using a randomized number table,to either a medication group(methylphenidate hydrochloride extended-release tablets and atomoxetine hydrochloride tablets)or a multimodal integrated intervention group(medication+parent training+behavior modification+sensory integration therapy+sand tray therapy),with 49 patients in each group.The clinical endpoint was the efficacy of the different intervention modalities.RESULTS The two groups of children with ADHD had comparable patient characteristics(P>0.05).Multimodal integrated intervention resulted in a significantly higher treatment efficacy(91.84%)than medication alone(75.51%)(P<0.05).Children who received the multimodal integrated intervention showed lower scores in the Conners Parent Symptom Questionnaire and the Weiss Functional Impairment Rating Scale than those treated with medication alone(P<0.05).The Sensory Integration Scale scores of children in the multimodal integrated intervention group were higher than those of children in the medication group(P<0.05).Children who received the multimodal integrated intervention had higher compliance and family satisfaction and a lower incidence of adverse events than those treated with medication alone(P<0.05).CONCLUSION Multimodal integrated intervention effectively alleviated symptoms associated with ADHD in children.It enhanced their memory and attention with high safety and parental satisfaction,demonstrating good potential for clinical promotion.展开更多
目的:分析国内外体医融合领域的研究现状、热点及趋势。方法:运用CiteSpace和VOSviewer软件对中国知网(CNKI)和科学引文索引(Web of Science)两大数据库中体医融合领域2013—2023年的研究文献进行可视化分析。结果:从发文数量看,2017年...目的:分析国内外体医融合领域的研究现状、热点及趋势。方法:运用CiteSpace和VOSviewer软件对中国知网(CNKI)和科学引文索引(Web of Science)两大数据库中体医融合领域2013—2023年的研究文献进行可视化分析。结果:从发文数量看,2017年以后国外体医融合领域文献增长迅速,国内文献增长速度较慢;从发文作者看,国外核心作者数量大于国内;从研究机构看,国内研究机构跨区域合作不明显,国外研究机构关系紧密;从高被引文献看,国内外研究方向有一定相似性,但侧重点不同;从关键词分析看,我国该领域研究相较于国外在先进性、多维性和深刻性方面存在一些滞后。结论:为实现健康中国的目标,国内学者应完善现有的理论体系,丰富研究方法,促成跨学科交叉融合研究,关注国际研究热点,优化中国体医融合领域研究。展开更多
基金Supported by Ningbo Medical Key Fostering Discipline Child Health Science,No.2022-F26Ningbo Science and Technology Plan Project Public Welfare Plan,No.2019C50099.
文摘BACKGROUND Attention-deficit/hyperactivity disorder(ADHD)is one of the most common disorders in child and adolescent psychiatry,with a prevalence of more than 5%.Despite extensive research on ADHD in the last 10 to 20 years,effective treatments are still lacking.Instead,the concept of ADHD seems to have become broader and more heterogeneous.Therefore,the diagnosis and treatment of ADHD remains challenging for clinicians.AIM To investigate the effects of a multimodal integrated intervention for children with ADHD.METHODS Between March 2019 and September 2020,a total of 100 children with ADHD who were diagnosed and treated at our hospital were assessed for eligibility,two of whom revoked their consent.A case-control study was conducted in which the children were equally assigned,using a randomized number table,to either a medication group(methylphenidate hydrochloride extended-release tablets and atomoxetine hydrochloride tablets)or a multimodal integrated intervention group(medication+parent training+behavior modification+sensory integration therapy+sand tray therapy),with 49 patients in each group.The clinical endpoint was the efficacy of the different intervention modalities.RESULTS The two groups of children with ADHD had comparable patient characteristics(P>0.05).Multimodal integrated intervention resulted in a significantly higher treatment efficacy(91.84%)than medication alone(75.51%)(P<0.05).Children who received the multimodal integrated intervention showed lower scores in the Conners Parent Symptom Questionnaire and the Weiss Functional Impairment Rating Scale than those treated with medication alone(P<0.05).The Sensory Integration Scale scores of children in the multimodal integrated intervention group were higher than those of children in the medication group(P<0.05).Children who received the multimodal integrated intervention had higher compliance and family satisfaction and a lower incidence of adverse events than those treated with medication alone(P<0.05).CONCLUSION Multimodal integrated intervention effectively alleviated symptoms associated with ADHD in children.It enhanced their memory and attention with high safety and parental satisfaction,demonstrating good potential for clinical promotion.
文摘目的:分析国内外体医融合领域的研究现状、热点及趋势。方法:运用CiteSpace和VOSviewer软件对中国知网(CNKI)和科学引文索引(Web of Science)两大数据库中体医融合领域2013—2023年的研究文献进行可视化分析。结果:从发文数量看,2017年以后国外体医融合领域文献增长迅速,国内文献增长速度较慢;从发文作者看,国外核心作者数量大于国内;从研究机构看,国内研究机构跨区域合作不明显,国外研究机构关系紧密;从高被引文献看,国内外研究方向有一定相似性,但侧重点不同;从关键词分析看,我国该领域研究相较于国外在先进性、多维性和深刻性方面存在一些滞后。结论:为实现健康中国的目标,国内学者应完善现有的理论体系,丰富研究方法,促成跨学科交叉融合研究,关注国际研究热点,优化中国体医融合领域研究。
