For deep tunnel projects,selecting an appropriate initial support distance is critical to improving the self-supporting capacity of surrounding rock.In this work,an intuitive method for determining the tunnel’s initi...For deep tunnel projects,selecting an appropriate initial support distance is critical to improving the self-supporting capacity of surrounding rock.In this work,an intuitive method for determining the tunnel’s initial support distance was proposed.First,based on the convergence-confinement method,a three-dimensional analytical model was constructed by combining an analytical solution of a non-circular tunnel with the Tecplot software.Then,according to the integral failure criteria of rock,the failure tendency coefficients of hard surrounding rock were computed and the spatial distribution plots of that were constructed.On this basis,the tunnel’s key failure positions were identified,and the relationship between the failure tendency coefficient at key failure positions and their distances from the working face was established.Finally,the distance from the working face that corresponds to the critical failure tendency coefficient was taken as the optimal support distance.A practical project was used as an example,and a reasonable initial support distance was successfully determined by applying the developed method.Moreover,it is found that the stability of hard surrounding rock decreases rapidly within the range of 1.0D(D is the tunnel diameter)from the working face,and tends to be stable outside the range of 1.0D.展开更多
Aplastic anemia （AA） and myelodysplastic syndrome （MDS） are both included in the bone marrow failure syndromes （BMFS）. AA is a group of diseases characterized by hematopoietic stem/progenitor cell damage, oerioh...Aplastic anemia （AA） and myelodysplastic syndrome （MDS） are both included in the bone marrow failure syndromes （BMFS）. AA is a group of diseases characterized by hematopoietic stem/progenitor cell damage, oerioheral blood cvtooenia, andclinical manifestations including anemia, bleeding and infection, which eventually lead to bone marrow failure. The incidence rate of AA in China is 7.4/10^6, higher than that in Western countries, among which the morbidity of acute AA and chronic AA （CAA） is 1.4/10^6 and 6.0/10^6, respectively.展开更多
Introduction Acetaminophen （APP） is one of the most common antipyretic analgesics and is generally considered as a safe drug. However, acute or accumulative overdose of it can cause liver damage, even liver failure...Introduction Acetaminophen （APP） is one of the most common antipyretic analgesics and is generally considered as a safe drug. However, acute or accumulative overdose of it can cause liver damage, even liver failure. Here we reported a case of an 11-year-old patient with acute liver failure （ALF） induced by taking 0.25 g APP orally, who was successfully treated by integrative Chinese and Western medicine.展开更多
基金Project(2021JLM-49) supported by Natural Science Basic Research Program of Shaanxi-Joint Fund of Hanjiang to Weihe River Valley Water Diversion Project,ChinaProject(42077248) supported by the National Natural Science Foundation of China
文摘For deep tunnel projects,selecting an appropriate initial support distance is critical to improving the self-supporting capacity of surrounding rock.In this work,an intuitive method for determining the tunnel’s initial support distance was proposed.First,based on the convergence-confinement method,a three-dimensional analytical model was constructed by combining an analytical solution of a non-circular tunnel with the Tecplot software.Then,according to the integral failure criteria of rock,the failure tendency coefficients of hard surrounding rock were computed and the spatial distribution plots of that were constructed.On this basis,the tunnel’s key failure positions were identified,and the relationship between the failure tendency coefficient at key failure positions and their distances from the working face was established.Finally,the distance from the working face that corresponds to the critical failure tendency coefficient was taken as the optimal support distance.A practical project was used as an example,and a reasonable initial support distance was successfully determined by applying the developed method.Moreover,it is found that the stability of hard surrounding rock decreases rapidly within the range of 1.0D(D is the tunnel diameter)from the working face,and tends to be stable outside the range of 1.0D.
文摘Aplastic anemia （AA） and myelodysplastic syndrome （MDS） are both included in the bone marrow failure syndromes （BMFS）. AA is a group of diseases characterized by hematopoietic stem/progenitor cell damage, oerioheral blood cvtooenia, andclinical manifestations including anemia, bleeding and infection, which eventually lead to bone marrow failure. The incidence rate of AA in China is 7.4/10^6, higher than that in Western countries, among which the morbidity of acute AA and chronic AA （CAA） is 1.4/10^6 and 6.0/10^6, respectively.
基金Supported by National Science and Technology Major Project (No.2012ZX10005010-004)
文摘Introduction Acetaminophen （APP） is one of the most common antipyretic analgesics and is generally considered as a safe drug. However, acute or accumulative overdose of it can cause liver damage, even liver failure. Here we reported a case of an 11-year-old patient with acute liver failure （ALF） induced by taking 0.25 g APP orally, who was successfully treated by integrative Chinese and Western medicine.
