Interactive Development of Heritage Resource Utilization and Cultural Creative Industry:A Case Study of Jingdezhen

Heritage resources provide profound historical and cultural connotations and earners for the cultural creative industry the development of cultural creative industry also promotes the sustainable development of heritage resources.Taking Jingdezhen for example,this paper analyzed local heritage resources and development of local cultural creative industry,on this basis proposed that key efforts should be devoted to develop ceramic culture creative industry,cultivate industrial agglomerations of considerable scale,and form industrial chain,in order to realize the high-efficiency transition from heritage resources to cultural creative industry,and eventually improve cultural taste and build the characteristic brand of the city.

Radial glia interact with primary olfactory axons to regulate development of the olfactory bulb

The developing olfactory system - merging of the periph- eral and central nervous systems： The olfactory system is responsible for the sense of smell and is comprised of a complex topographic map that regenerates throughout life. In rodents each olfactory sensory neuron expresses one of N 1,300 odorant receptors with the neurons being distributed mosaically within the epithelium. The axons of the sensory neurons do not maintain near-neighbour relationships and instead project to disparate topographic targets in the olfac- tory bulb within the central nervous system. The develop- ment of the targets relies on the intermingling of the sensory axons with the interneurons, glia and second order neurons of the olfactory bulb. Thus the formation of the olfactory system involves the coordinated integration of the axons of the peripheral olfactory sensory neurons with the cells of the olfactory bulb.

FRUCTOKINASE-LIKE PROTEIN 1 interacts with TRXz to regulate chloroplast development in rice

Chloroplast genes are transcribed by the plastidencoded RNA polymerase（PEP） or nucleus-encoded RNA polymerase. FRUCTOKINASE-LIKE PROTEINS（FLNs） are phosphofructokinase-B（Pfk B）-type carbohydrate kinases that act as part of the PEP complex; however, the molecular mechanisms underlying FLN activity in rice remain elusive.Previously, we identified and characterized a heat-stress sensitive albino（hsa_1） mutant in rice. Map-based cloning revealed that HSA_1 encodes a putative OsFLN_2. Here, we further demonstrated that knockdown or knockout of the OsFLN_1, a close homolog of HSA_1/OsFLN_2, considerably inhibits chloroplast biogenesis and the fln_1 knockout mutants, created by clustered regularly interspaced short palindromic repeats（CRISPR） and CRISPR-associate protein_9, exhibit severe albino phenotype and seedling lethality. Moreover, OsFLN_1 localizes to the chloroplast.Yeast two-hybrid, pull-down and bimolecular fluorescencecomplementation experiments revealed that OsFLN_1 and HSA_1/OsFLN_2 interact with THIOREDOXINZ（OsTRXz） to regulate chloroplast development. In agreement with this,knockout of OsTRXz resulted in a similar albino and seedling lethality phenotype to that of the fln_1 mutants. Quantitative reverse transcription polymerase chain reaction and immunoblot analysis revealed that the transcription and translation of PEP-dependent genes were strongly inhibited in fln_1 and trxz mutants, indicating that loss of OsFLN_1, HSA_1/OsFLN_2, or OsTRXz function perturbs the stability of the transcriptionally active chromosome complex and PEP activity. These results show that OsFLN_1 and HSA_1/OsFLN_2 contribute to chloroplast biogenesis and plant growth.

VisComposer: A Visual Programmable Composition Environment for Information Visualization

As the amount of data being collected has increased,the need for tools that can enable the visual exploration of data has also grown.This has led to the development of a variety of widely used programming frameworks for information visualization.Unfortunately,such frameworks demand comprehensive visualization and coding skills and require users to develop visualization from scratch.An alternative is to create interactive visualization design environments that require lttle to no programming.However,these tools only supports a small portion of visual formns.We present a programmable integrated development environment(IDE),VisComposer,that supports the development of expressive visualization using a drag and-drop visual interface.Vis-Composer exposes the programmability by customizing desired components within a modular-ized visualization composition pipeline,effectively balancing the capability gap between expert coders and visualization artists.The implemented system empowers users to compose compre-bensive visualizations with real-time preview and optimization features,and supports prototyp-ing,sharing and reuse of the effects by means of an intuitive visual composer.Visual program-ming and textual programming integrated in our system allow users to compose more complex visual effects while retaining the simplicity of use.We demonstrate the performance of VisCom-poser with a variety of examples and an informal user evaluation.