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Neurochemical mechanism of the gastrointestinal interdigestive migrating motor complex in rats with acute inflammatory stomach ache 被引量:1
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作者 Xiaoli Xu Qin Li +1 位作者 Lv Zhou Liqiang Ru 《Neural Regeneration Research》 SCIE CAS CSCD 2012年第27期2136-2143,共8页
The normal gastrointestinal interdigestive migrating motor complex cycle was interrupted, and paroxysmal contraction appeared after formaldehyde-induced stomach ache. Activities of nitric oxide synthase, acetylcholine... The normal gastrointestinal interdigestive migrating motor complex cycle was interrupted, and paroxysmal contraction appeared after formaldehyde-induced stomach ache. Activities of nitric oxide synthase, acetylcholinesterase and vasoactive intestinal peptide neurons were significantly reduced, whereas activities of calcitonin gene-related peptide neurons were significantly increased in the pyloric sphincter muscular layer, myenteric nerve plexus and submucous nerve plexus. Electroacupuncture at Zusanfi (ST36) suppressed paroxysmal contraction in rats with formaldehyde-induced stomach ache, and neurons in the enteric nervous system were normal. These results indicated that nitrergic neurons, cholinergic neurons, vasoactive intestinal peptide neurons and calcitonin gene-related peptide neurons in the enteric nervous system may be involved in changes to the gastrointestinal interdigestive migrating motor complex following stomach ache, and that electroacupuncture can regulate this process. 展开更多
关键词 pyloric sphincter inflammatory pain interdigestive migrating motor complex enteric nervoussystem ELECTROACUPUNCTURE neural regeneration
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Relationship between Gastric Stasis in the Remnant Stomach and Interdigestive Migrating Complex in Patients after Pylorus-Preserving Gastrectomy for Gastric Cancer
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作者 Ryouichi Tomita Kenichi Sakurai +2 位作者 Shigeru Fujisaki Takeo Azuhata Yuko Takamoto 《Journal of Cancer Therapy》 2018年第9期639-649,共11页
Objectives: The demerit of pylorus-preserving gastrectomy (PPG) is gastric stasis in the remnant stomach (GSRS). We investigated the relationship between postgastrectomy disorder (PGD), especially GSRS, and interdiges... Objectives: The demerit of pylorus-preserving gastrectomy (PPG) is gastric stasis in the remnant stomach (GSRS). We investigated the relationship between postgastrectomy disorder (PGD), especially GSRS, and interdigestive migrating complex (IMC) in PPG patients. Background: The cause of GSRS is still unknown. Therefore, we studied relationship between GSRS and IMC. Methods: 24 PPG patients (16 men and 8 women;mean, 61.2 years) were divided into groups A (12 patients without GSRS) and B (12 patients with GSRS). The relationship between GSRS and IMC was studied. Results: Length of the antral cuff (LAC) was significantly longer in group A than group B (P < 0.0001). IMC and appetite were significantly more common in group A than in group B (P = 0.0465, P = 0.0186, respectively). Postprandial abdominal fullness (PAF) was significantly more common in group B than in group A (P = 0.0061). Reflux esophagitis (RE) and body weight loss were found in group B more than in group A. Dumping syndrome was not found in either group. Endoscopic gastritis was found significantly more in group B than in group A (P = 0.0047). Conclusions: In PPG patients with a short LAC, GSRS may occur by the decrease of IMC occurrence. 展开更多
关键词 GASTRIC Stasis in the Remnant Stomach interdigestive Migrating Complex Pylorus-Preserving GASTRECTOMY GASTRIC Cancer
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Effect of electroacupuncture in Weijing points on gastrointestinal interdigestive migrating motor complex and brain gut peptides release in dogs
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作者 ZHOU Lu WANG Lijian +1 位作者 YUN Tianyou WANG Ling 《Chinese Science Bulletin》 SCIE EI CAS 2001年第10期843-850,共8页
Interdigestive gastrointestinal migrating motor complex (MMC) activities were recorded by strain gauge implanted on the serosa in 7 conscious dogs. We studied the effects of electroacupuncture (EAP) Weijing points Zus... Interdigestive gastrointestinal migrating motor complex (MMC) activities were recorded by strain gauge implanted on the serosa in 7 conscious dogs. We studied the effects of electroacupuncture (EAP) Weijing points Zusanli (S36), Tianshu (S25), Liangmen (S21) on MMC and release of motilin and gastrin, and compared them with that of EAP Pangguangjing points. The results indicated that EAP Weijing points could not only strengthen MMC contractions in antrum, duodenum and proximal jejunum, but also increase plasma concentration of motilin and gastrin. Anti-motilin serum, proglumide, atropine, or hexamethonium could markedly block the effect of EAP on reinforcing MMC contraction and release of motilin and gastrin. We could get the conclusions that such enhancing effect of EAP Weijing points on MMC and brain-gut peptides release is mediated by motilin and gastrin, on which both cholinergic nerve and sympathetic nerve play important roles. 展开更多
关键词 interdigestive migrating motor complex (MMC) elec-troacupuncture MOTILIN gastrin.
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Gastrointestinal migrating motor complex during early stage of cholesterol gallstone formation in guinea pigs 被引量:1
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作者 Wang Ling Bai Wenyuan +1 位作者 Ma Yongzhi Gu Yong 《Journal of Medical Colleges of PLA(China)》 CAS 2008年第1期9-14,共6页
Objective: To determine the changes of gastrointestinal migrating motor complex (MMC) during the early stage of cholesterol gallstone formation. Methods:Totally 45 healthy adult guinea pigs were randomly and equal... Objective: To determine the changes of gastrointestinal migrating motor complex (MMC) during the early stage of cholesterol gallstone formation. Methods:Totally 45 healthy adult guinea pigs were randomly and equally divided into 3 groups, that is, normal control, group B (1% cholesterol diet for 2 weeks) and group C (1% cholesterol diet for 4 weeks). Three pairs of silver electrodes were inserted into the gastric antrum, duodenum and jejunum of every animal respectively. Record of gastrointestinal MMC of these guinea pigs were recorded and analyzed. Gallbladder bile was taken to detect the formation of cholesterol gallstone. Results: There were only 29 guinea pigs living. The MMC cycle time and the duration of phase Ⅱ were prolonged significantly and gradually compared with the control group (P〈0.01), but the duration of phase Ⅲ became significantly and gradually shorter. Conclusion: During the early stage of cholesterol gallstone formation, the MMC cycle time and the duration of phase Ⅱ are prolonged and the duration of phase Ⅲ is shortened. 展开更多
关键词 High cholesterol diet interdigestive stage Migrating motor complex
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