The optical potential ambiguity is a long-standing problem in the analysis of elastic scattering data.For a specific collid-ing system,ambiguous potential families can lead to different behaviors in the nearside and f...The optical potential ambiguity is a long-standing problem in the analysis of elastic scattering data.For a specific collid-ing system,ambiguous potential families can lead to different behaviors in the nearside and farside scattering components.By contrast,the envelope method can decompose the experimental data into two components with negative and positive deflection angles,respectively.Hence,a question arises as to whether the comparison between the calculated nearside(or farside)component and the derived positive-deflection-angle(or negative-deflection-angle)component can help analyze the potential ambiguity problem.In this study,we conducted a trial application of the envelope method to the potential ambiguity problem.The envelope method was improved by including uncertainties in the experimental data.The colliding systems of 16O+28Si at 215.2 MeV and 12C+12C at 1016 MeV were considered in the analyses.For each colliding system,the angular distribution experimental data were described nearly equally well by two potential sets,one of which is“surface transpar-ent”and the other is refractive.The calculated angular distributions were decomposed into nearside and farside scattering components.Using the improved envelope method,the experimental data were decomposed into the positive-deflection-angle and negative-deflection-angle components,which were then compared with the calculated nearside and farside components.The capability of the envelope method to analyze the potential ambiguities was also discussed.展开更多
The development of machine learning technology enables more robust real-time earthquake monitoring through automated implementations. However, the application of machine learning to earthquake location problems faces ...The development of machine learning technology enables more robust real-time earthquake monitoring through automated implementations. However, the application of machine learning to earthquake location problems faces challenges in regions with limited available training data. To address the issues of sparse event distribution and inaccurate ground truth in historical seismic datasets, we expand the training dataset by using a large number of synthetic envelopes that closely resemble real data and build an earthquake location model named ENVloc. We propose an envelope-based machine learning workflow for simultaneously determining earthquake location and origin time. The method eliminates the need for phase picking and avoids the accumulation of location errors resulting from inaccurate picking results. In practical application, ENVloc is applied to several data intercepted at different starting points. We take the starting point of the time window corresponding to the highest prediction probability value as the origin time and save the predicted result as the earthquake location. We apply ENVloc to observed data acquired in the southern Sichuan Basin, China, between September 2018 and March 2019. The results show that the average difference with the catalog in latitude, longitude, depth, and origin time is 0.02°,0.02°, 2 km, and 1.25 s, respectively. These suggest that our envelope-based method provides an efficient and robust way to locate earthquakes without phase picking, and can be used in earthquake monitoring in near-real time.展开更多
Substantially glazed facades are extensively used in contemporary high-rise buildings to achieve attractive architectural aesthetics.Inherent conflicts exist among architectural aesthetics,building energy consumption,...Substantially glazed facades are extensively used in contemporary high-rise buildings to achieve attractive architectural aesthetics.Inherent conflicts exist among architectural aesthetics,building energy consumption,and solar energy harvesting for glazed facades.In this study,we addressed these conflicts by introducing a new dynamic and vertical photovoltaic integrated building envelope(dvPVBE)that offers extraordinary flexibility with weather-responsive slat angles and blind positions,superior architectural aesthetics,and notable energy-saving potential.Three hierarchical control strategies were proposed for different scenarios of the dvPVBE:power generation priority(PGP),natural daylight priority(NDP),and energy-saving priority(ESP).Moreover,the PGP and ESP strategies were further analyzed in the simulation of a dvPVBE.An office room integrated with a dvPVBE was modeled using EnergyPlus.The influence of the dvPVBE in improving the building energy efficiency and corresponding optimal slat angles was investigated under the PGP and ESP control strategies.The results indicate that the application of dvPVBEs in Beijing can provide up to 131%of the annual energy demand of office rooms and significantly increase the annual net energy output by at least 226%compared with static photovoltaic(PV)blinds.The concept of this novel dvPVBE offers a viable approach by which the thermal load,daylight penetration,and energy generation can be effectively regulated.展开更多
BACKGROUND Occult hepatitis B infection(OBI)is characterized by the detection of hepatitis B virus(HBV)DNA in serum(usually HBV DNA<200 IU/mL)or the liver but negativity for hepatitis B surface antigen(HBsAg).The d...BACKGROUND Occult hepatitis B infection(OBI)is characterized by the detection of hepatitis B virus(HBV)DNA in serum(usually HBV DNA<200 IU/mL)or the liver but negativity for hepatitis B surface antigen(HBsAg).The diagnosis of OBI relies on the sensitivity of assays used in the detection of HBV DNA and HBsAg.HBsAg assays with inadequate sensitivity or inability to detect HBV S variants may lead to misdiagnosis of OBI in people with overt HBV infection.CASE SUMMARY We report a HBsAg-negative but hepatitis B envelope antigen-positive patient who had a significant HBV DNA level.The patient was initially diagnosed as having OBI.However,sequence analysis revealed a unique insertion of amino acid residues at positions 120-124 in the S protein,which affects the formation of a disulfide bond that is associated with the formation of a loop.It is well known that there is an overlap between the S protein and Pol protein.We found that this new insertion site occurred in polymerase/reverse transcriptase domain,indi-cating that this insertion might be involved in HBV pathogenicity.The patient was finally diagnosed with a false OBI.CONCLUSION An insertion of amino acid residues at positions 120-124 of the S protein affects the formation of immunodominant epitopes and results in negative HBsAg levels.展开更多
Fine structure and elemental composition of envelopes of 10 taxa of Trachelomonas and Strombomonas from natural freshwater bodies in China were studied and phylogeny of both genera were discussed. The results indicate...Fine structure and elemental composition of envelopes of 10 taxa of Trachelomonas and Strombomonas from natural freshwater bodies in China were studied and phylogeny of both genera were discussed. The results indicate that iron (Fe) and silicon (Si) are the primary mineral elements of the envelopes. Composition of mineral elements was uncorrelated with envelope color, however, it was highly correlated with the microarchitecture of the envelopes. Content of Si was higher than that of Fe in all species of Strombomonas and some species of Trachelomonas with rough surface. In most species of Trachelomonas, especially those with dense and smoothy surface, content of Fe was higher than that of Si. Based on the above results, we propose to assign those species of Strombomonas into Trachelomonas and consider them as a group of the latter. These species were the most primitive among the group with envelopes in Euglenaceae.展开更多
The absence of low-frequency information in seismic data is one of the most difficult problems in elastic full waveform inversion. Without low-frequency data, it is difficult to recover the long-wavelength components ...The absence of low-frequency information in seismic data is one of the most difficult problems in elastic full waveform inversion. Without low-frequency data, it is difficult to recover the long-wavelength components of subsurface models and the inversion converges to local minima. To solve this problem, the elastic envelope inversion method is introduced. Based on the elastic envelope operator that is capable of retrieving low- frequency signals hidden in multicomponent data, the proposed method uses the envelope of multicomponent seismic signals to construct a misfit function and then recover the long- wavelength components of the subsurface model. Numerical tests verify that the elastic envelope method reduces the inversion nonlinearity and provides better starting models for the subsequent conventional elastic full waveform inversion and elastic depth migration, even when low frequencies are missing in multicomponent data and the starting model is far from the true model. Numerical tests also suggest that the proposed method is more effective in reconstructing the long-wavelength components of the S-wave velocity model. The inversion of synthetic data based on the Marmousi-2 model shows that the resolution of conventional elastic full waveform inversion improves after using the starting model obtained using the elastic envelope method. Finally, the limitations of the elastic envelope inversion method are discussed.展开更多
As in homology, the notion of injectivity is introduced in the category whose objects are Hilbert C * module over a C * algebra and whose morphism are bounded module operators. The definition of injective envelope...As in homology, the notion of injectivity is introduced in the category whose objects are Hilbert C * module over a C * algebra and whose morphism are bounded module operators. The definition of injective envelopes of an extension of a Hilbert C * modules over a C * algebra is introduced, and is characterized in terms of the injectivity and essence. It is shown that every Hilbert C * module has a unique (up to H isometrics) injective envelope if it exists. It is also shown that an extension of a Hilbert C * module is an injective envelope if and only if it is an injective and essential extension. Moreover, every Hilbert C * module over a W * algebra has a unique (up to H isometrics) injective envelope and the injective envelope of a Hilbert C * module H is maximal essential extension of H .展开更多
The Shipboard Operation Envelope(SOE) is the safe boundary of the helicopter/ship dynamic interface. The night deck on a ship is usually behind the hangar, where the airflow is turbulent due to the influence of the up...The Shipboard Operation Envelope(SOE) is the safe boundary of the helicopter/ship dynamic interface. The night deck on a ship is usually behind the hangar, where the airflow is turbulent due to the influence of the upper structure, wind and ship speed. The turbulent airnow is the major adverse factor for the safety of shipboard operations. In this paper, the night deck abbot is analysed as the superposition of two penyndicular 2-D airflows.N-S equations are used to calculate the velocity field and the range of turbulent airflow using finite element method. The result is correspondent well with test. Incorporating the influence of the airflow and giving some restrictions on the movements of the ship and on the control margin of the helicopter, the operation envelopes are calculated. The operation envelopes include three types for hovering over the deck, taking-off from and landing on ship, and landing with a landing-aid system. These results are helpful to the pilot training and night safety.展开更多
The vibration signal contains a wealth of sensitive information which reflects the running status of the equipment. It is one of the most important steps for precise diagnosis to decompose the signal and extracts the ...The vibration signal contains a wealth of sensitive information which reflects the running status of the equipment. It is one of the most important steps for precise diagnosis to decompose the signal and extracts the effective information properly. The traditional classical adaptive signal decomposition method, such as EMD, exists the problems of mode mixing, low decomposition accuracy etc. Aiming at those problems, EAED(extreme average envelope decomposition) method is presented based on EMD. EAED method has three advantages. Firstly, it is completed through midpoint envelopment method rather than using maximum and minimum envelopment respectively as used in EMD. Therefore, the average variability of the signal can be described accurately. Secondly, in order to reduce the envelope errors during the signal decomposition, replacing two envelopes with one envelope strategy is presented. Thirdly, the similar triangle principle is utilized to calculate the time of extreme average points accurately. Thus, the influence of sampling frequency on the calculation results can be significantly reduced. Experimental results show that EAED could separate out single frequency components from a complex signal gradually. EAED could not only isolate three kinds of typical bearing fault characteristic of vibration frequency components but also has fewer decomposition layers. EAED replaces quadratic enveloping to an envelope which ensuring to isolate the fault characteristic frequency under the condition of less decomposition layers. Therefore, the precision of signal decomposition is improved.展开更多
Efficiency and linearity of the microwave power amplifier are critical elements for mobile communication systems. A memory polynomial baseband predistorter based on an indirect learning architecture is presented for i...Efficiency and linearity of the microwave power amplifier are critical elements for mobile communication systems. A memory polynomial baseband predistorter based on an indirect learning architecture is presented for improving the linearity of an envelope tracing (ET) amplifier with application to a wireless transmitter. To deal with large peak-to-average ratio (PAR) problem, a clipping procedure for the input signal is employed. Then the system performance is verified by simulation results. For a single carrier wideband code division multiple access (WCDMA) signal of 16-quadrature amplitude modulation (16-QAM), about 2% improvement of the error vector magnitude (EVM) is achieved at an average output power of 45.5 dBm and gain of 10.6 dB, with adjacent channel leakage ratio (ACLR) of -64.55 dBc at offset frequency of 5 MHz. Moreover, a three-carrier WCDMA signal and a third-generation (3G) long term evolution (LTE) signal are used as test signals to demonstrate the performance of the proposed linearization scheme under different bandwidth signals.展开更多
Hepatitis B virus(HBV),a major cause of human liver disease worldwide,encodes three envelope proteins needed for the attachment and entry of the virus into susceptible host cells.A second virus,hepatitis delta virus,w...Hepatitis B virus(HBV),a major cause of human liver disease worldwide,encodes three envelope proteins needed for the attachment and entry of the virus into susceptible host cells.A second virus,hepatitis delta virus,which is known to enhance liver disease in HBV infected patients,diverts the same HBV envelope proteins to achieve its own assembly and infection.In the lab,lentiviral vectors based on human immunodeficiency virus type 1 can be assembled using the HBV envelope proteins,and will similarly infect susceptible cells.This article provides a partial review and some personal reflections of how these three viruses infect and of how recipient cells become susceptible,along with some consideration of questions that remain to be answered.展开更多
A simple shallow-water model on an equatorial β-plane is employed to investigate the nonlinear equatorial Rossby solitons in a mean zonal flow with meridional shear by the asymptotic method of multiple scales. The cu...A simple shallow-water model on an equatorial β-plane is employed to investigate the nonlinear equatorial Rossby solitons in a mean zonal flow with meridional shear by the asymptotic method of multiple scales. The cubic nonlinear Schr?dinger (NLS, for short) equation, satisfied for large amplitude equatorial envelope Rossby solitons in shear basic flow, is derived. The effects of basic flow shear on the nonlinear equatorial Rossby solitons are also analyzed. Key words Envelope solitons - NLS This work was supported by the Foundation for University Key Teacher by the Ministry of Education.展开更多
Constant envelope with a fractional Fourier transformorthogonal frequency division multiplexing(CE-FrFT-OFDM)is a special case of a constant envelope OFDM(CE-OFDM),both being energy efficient wireless communication te...Constant envelope with a fractional Fourier transformorthogonal frequency division multiplexing(CE-FrFT-OFDM)is a special case of a constant envelope OFDM(CE-OFDM),both being energy efficient wireless communication techniques with a 0 dB peak to average power ratio(PAPR).However,with the proper selection of fractional order,the first technique has a high bit error rate(BER)performance in the frequency-time selective channels.This paper performs further analysis of CE-FrFT-OFDM by examining its spectral efficiency(SE)and energy efficiency(EE)and compare to the famous OFDM and FrFT-OFDM techniques.Analytical and comprehensive simulations conducted show that,the CE-FrFT-OFDM has five times the EE of OFDM and FrFT-OFDM systems with a slightly less SE.Increasing CE-FrFT-OFDM’s transmission power by increasing its amplitude to 1.7 increases its SE to match that of the OFDM and FrFT-OFDM systems while slightly reducing its EE by 20%to be four times that of OFDM and FrFTOFDM systems.OFDM and FrFT-OFDM’s amplitude fluctuations cause rapid changing output back-off(OBO)power requirements and further reduce power amplifier(PA)efficiency while CE-FrFTOFDM stable operational linear range makes it a better candidate and outperforms the other techniques when their OBO exceeds 1.7.Higher EE and low BER in time-frequency selective channel are attracting features for CE-FrFT-OFDM deployment in mobile devices.展开更多
The cylindrical worm processed by annular grinding wheel envelope in two degree of freedom motion state is a novel worm. This paper explains the shaping principle of such a worm. To improve meshing quality and the p...The cylindrical worm processed by annular grinding wheel envelope in two degree of freedom motion state is a novel worm. This paper explains the shaping principle of such a worm. To improve meshing quality and the properties of contact and lubrication, the multi objective optimization has been conducted for the first time to the parameters of such a worm pair by the fuzzy optimal method. The results show that, the shape of the contact line is visibly more sloped than before being optimized, lubrication angle is apparently bigger, and the distribution of contact lines is much improved.展开更多
Pepper mild mottle virus(PMMoV)is a devastating viral pathogen of pepper(Capsicum annuum)but it is unclear whether and how peppers protect against PMMoV infection.The expression of the chloroplast outer membrane prote...Pepper mild mottle virus(PMMoV)is a devastating viral pathogen of pepper(Capsicum annuum)but it is unclear whether and how peppers protect against PMMoV infection.The expression of the chloroplast outer membrane protein 24(OMP24)of C.annuum was upregulated under PMMoV infection and it interacted with PMMoV coat protein(CP).Silencing of OMP24 in either C.annuum or Nicotiana benthamiana facilitated PMMoV infection,whereas overexpression of N.benthamiana OMP24 in transgenic plants inhibited PMMoV infection.Both C.annuum OMP24(CaOMP24)and N.benthamiana OMP24(NbOMP24)localized to the chloroplast and have a moderately hydrophobic transmembrane domain that is necessary for their localization.Overexpression of CaOMP24 induced stromules,perinuclear chloroplast clustering,and accumulation of reactive oxygen species(ROS),the typical defense responses of chloroplasts transferring the retrograde signaling to the nucleus to regulate resistance genes.The expression of PR1 and PR2 was also upregulated significantly in plants overexpressing OMP24.Self-interaction of OMP24 was demonstrated and was required for OMP24-mediated plant defense.Interaction with PMMoV CP interfered with the self-interaction of OMP24 and impaired OMP24-induced stromules,perinuclear chloroplast clustering and ROS accumulation.The results demonstrate the defense function of OMP24 in pepper during viral infection and suggest a possible mechanism by which PMMoV CP modulates the plant defense to facilitate viral infection.展开更多
The CD4 binding site(CD4bs) of envelope glycoprotein(Env) is an important conserved target for anti-human immunodeficiency virus type 1(HIV-1) neutralizing antibodies. Neutralizing monoclonal antibodies IgG1 b12(b12) ...The CD4 binding site(CD4bs) of envelope glycoprotein(Env) is an important conserved target for anti-human immunodeficiency virus type 1(HIV-1) neutralizing antibodies. Neutralizing monoclonal antibodies IgG1 b12(b12) could recognize conformational epitopes that overlap the CD4 bs of Env. Different virus strains, even derived from the same individual, showed distinct neutralization susceptibility to b12. We examined the key amino acid residues affecting b12 neutralization susceptibility using single genome amplification and pseudovirus neutralization assay. Eleven amino acid residues were identified that affect the sensitivity of Env to b12. Through site-directed mutagenesis, an amino acid substitution at position 182 in the V2 region of Env was confirmed to play a key role in regulating the b12 neutralization susceptibility. The introduction of V182 L to a resistant strain enhanced its sensitivity to b12 more than twofold. Correspondingly, the introduction of L182 V to a sensitive strain reduced its sensitivity to b12 more than tenfold. Amino acid substitution at positions 267 and 346 could both enhance the sensitivity to b12 more than twofold. However, no additive effect was observed when the three site mutageneses were introduced into the same strain, and the sensitivity was equivalent to the single V182 L mutation. CRF07_BC is a major circulating recombinant form of HIV-1 prevalent in China. Our data may provide important information for understanding the molecular mechanism regulating the neutralization susceptibility of CRF07_BC viruses to b12 and may be helpful for a vaccine design targeting the CD4 bs epitopes.展开更多
One of the important issues in the system identification and the spectrum analysis is the frequency resolution, i.e., the capability of distinguishing between two or more closely spaced frequency components. In the mo...One of the important issues in the system identification and the spectrum analysis is the frequency resolution, i.e., the capability of distinguishing between two or more closely spaced frequency components. In the modal identification by the empirical mode decomposition (EMD) method, because of the separating capability of the method, it is still a challenge to consistently and reliably identify the parameters of structures of which modes are not well separated. A new method is introduced to generate the intrin- sic mode functions (IMFs) through the filtering algorithm based on the wavelet packet decomposition (GIFWPD). In this paper, it is demonstrated that the CIFWPD method alone has a good capability of separating close modes, even under the severe condition beyond the critical frequency ratio limit which makes it impossible to separate two closely spaced harmonics by the EMD method. However, the GIFWPD-only based method is impelled to use a very fine sampling frequency with consequent prohibitive computational costs. Therefore, in order to decrease the computational load by reducing the amount of samples and improve the effectiveness of separation by increasing the frequency ratio, the present paper uses a combination of the complex envelope displacement analysis (CEDA) and the GIFWPD method. For the validation, two examples from the previous works are taken to show the results obtained by the GIFWPD-only based method and by combining the CEDA with the GIFWPD method.展开更多
Envelope inversion(El)is an efficient tool to mitigate the nonlinearity of conventional full waveform inversion(FWI)by utilizing the ultralow-frequency component in the seismic data.However,the performance of envelope...Envelope inversion(El)is an efficient tool to mitigate the nonlinearity of conventional full waveform inversion(FWI)by utilizing the ultralow-frequency component in the seismic data.However,the performance of envelope inversion depends on the frequency component and initial model to some extent.To improve the convergence ability and avoid the local minima issue,we propose a convolution-based envelope inversion method to update the low-wavenumber component of the velocity model.Besides,the multi-scale inversion strategy(MCEI)is also incorporated to improve the inversion accuracy while guaranteeing the global convergence.The success of this method relies on modifying the original envelope data to expand the overlap region between observed and modeled envelope data,which in turn expands the global minimum basin of misfit function.The accurate low-wavenumber component of the velocity model provided by MCEI can be used as the migration model or an initial model for conventional FWI.The numerical tests on simple layer model and complex BP 2004 model verify that the proposed method is more robust than El even when the initial model is coarse and the frequency component of data is high.展开更多
This study aimed to investigate the effect of artificial weathering test on the photoaging behavior of TPU films. Changes in mechanical properties, morphology and chemical structures are studied by tensile test, scann...This study aimed to investigate the effect of artificial weathering test on the photoaging behavior of TPU films. Changes in mechanical properties, morphology and chemical structures are studied by tensile test, scanning electron microscopy, atomic force microscopy, Fourier-transformed infrared, and X-ray photoelectron spectroscopy. The results show that the photoaging negatively affects the initial modulus and stress at break values of TPU films. The surface of the specimen that is exposed to irradiation becomes rough, and some visible micro-defects such as blisters and voids can be detected. The morphology of the fracture surfaces illustrates that irradiation reduces the plasticity but increases the brittleness of the TPU films. The chemical structure analyses of the accelerated aged films prove that chemical structural changes in TPU films occur. The irradiation may break the long molecular chains on the surface of the specimens and form the lowmolecular weight oxygen-containing groups. The number of chain scissions increases with the increase in exposure time.展开更多
基金This work was supported by the National Natural Science Foundation of China(Nos.12005047 and U1832105).
文摘The optical potential ambiguity is a long-standing problem in the analysis of elastic scattering data.For a specific collid-ing system,ambiguous potential families can lead to different behaviors in the nearside and farside scattering components.By contrast,the envelope method can decompose the experimental data into two components with negative and positive deflection angles,respectively.Hence,a question arises as to whether the comparison between the calculated nearside(or farside)component and the derived positive-deflection-angle(or negative-deflection-angle)component can help analyze the potential ambiguity problem.In this study,we conducted a trial application of the envelope method to the potential ambiguity problem.The envelope method was improved by including uncertainties in the experimental data.The colliding systems of 16O+28Si at 215.2 MeV and 12C+12C at 1016 MeV were considered in the analyses.For each colliding system,the angular distribution experimental data were described nearly equally well by two potential sets,one of which is“surface transpar-ent”and the other is refractive.The calculated angular distributions were decomposed into nearside and farside scattering components.Using the improved envelope method,the experimental data were decomposed into the positive-deflection-angle and negative-deflection-angle components,which were then compared with the calculated nearside and farside components.The capability of the envelope method to analyze the potential ambiguities was also discussed.
基金the financial support of the National Key R&D Program of China(2021YFC3000701)the China Seismic Experimental Site in Sichuan-Yunnan(CSES-SY)for providing data for this study.
文摘The development of machine learning technology enables more robust real-time earthquake monitoring through automated implementations. However, the application of machine learning to earthquake location problems faces challenges in regions with limited available training data. To address the issues of sparse event distribution and inaccurate ground truth in historical seismic datasets, we expand the training dataset by using a large number of synthetic envelopes that closely resemble real data and build an earthquake location model named ENVloc. We propose an envelope-based machine learning workflow for simultaneously determining earthquake location and origin time. The method eliminates the need for phase picking and avoids the accumulation of location errors resulting from inaccurate picking results. In practical application, ENVloc is applied to several data intercepted at different starting points. We take the starting point of the time window corresponding to the highest prediction probability value as the origin time and save the predicted result as the earthquake location. We apply ENVloc to observed data acquired in the southern Sichuan Basin, China, between September 2018 and March 2019. The results show that the average difference with the catalog in latitude, longitude, depth, and origin time is 0.02°,0.02°, 2 km, and 1.25 s, respectively. These suggest that our envelope-based method provides an efficient and robust way to locate earthquakes without phase picking, and can be used in earthquake monitoring in near-real time.
基金supported by the National Natural Science Foundation of China(52078269 and 52325801).
文摘Substantially glazed facades are extensively used in contemporary high-rise buildings to achieve attractive architectural aesthetics.Inherent conflicts exist among architectural aesthetics,building energy consumption,and solar energy harvesting for glazed facades.In this study,we addressed these conflicts by introducing a new dynamic and vertical photovoltaic integrated building envelope(dvPVBE)that offers extraordinary flexibility with weather-responsive slat angles and blind positions,superior architectural aesthetics,and notable energy-saving potential.Three hierarchical control strategies were proposed for different scenarios of the dvPVBE:power generation priority(PGP),natural daylight priority(NDP),and energy-saving priority(ESP).Moreover,the PGP and ESP strategies were further analyzed in the simulation of a dvPVBE.An office room integrated with a dvPVBE was modeled using EnergyPlus.The influence of the dvPVBE in improving the building energy efficiency and corresponding optimal slat angles was investigated under the PGP and ESP control strategies.The results indicate that the application of dvPVBEs in Beijing can provide up to 131%of the annual energy demand of office rooms and significantly increase the annual net energy output by at least 226%compared with static photovoltaic(PV)blinds.The concept of this novel dvPVBE offers a viable approach by which the thermal load,daylight penetration,and energy generation can be effectively regulated.
基金Supported by the Shanghai Municipal Commission of Health and Family Planning,No.PKJ2018-Y05.
文摘BACKGROUND Occult hepatitis B infection(OBI)is characterized by the detection of hepatitis B virus(HBV)DNA in serum(usually HBV DNA<200 IU/mL)or the liver but negativity for hepatitis B surface antigen(HBsAg).The diagnosis of OBI relies on the sensitivity of assays used in the detection of HBV DNA and HBsAg.HBsAg assays with inadequate sensitivity or inability to detect HBV S variants may lead to misdiagnosis of OBI in people with overt HBV infection.CASE SUMMARY We report a HBsAg-negative but hepatitis B envelope antigen-positive patient who had a significant HBV DNA level.The patient was initially diagnosed as having OBI.However,sequence analysis revealed a unique insertion of amino acid residues at positions 120-124 in the S protein,which affects the formation of a disulfide bond that is associated with the formation of a loop.It is well known that there is an overlap between the S protein and Pol protein.We found that this new insertion site occurred in polymerase/reverse transcriptase domain,indi-cating that this insertion might be involved in HBV pathogenicity.The patient was finally diagnosed with a false OBI.CONCLUSION An insertion of amino acid residues at positions 120-124 of the S protein affects the formation of immunodominant epitopes and results in negative HBsAg levels.
文摘Fine structure and elemental composition of envelopes of 10 taxa of Trachelomonas and Strombomonas from natural freshwater bodies in China were studied and phylogeny of both genera were discussed. The results indicate that iron (Fe) and silicon (Si) are the primary mineral elements of the envelopes. Composition of mineral elements was uncorrelated with envelope color, however, it was highly correlated with the microarchitecture of the envelopes. Content of Si was higher than that of Fe in all species of Strombomonas and some species of Trachelomonas with rough surface. In most species of Trachelomonas, especially those with dense and smoothy surface, content of Fe was higher than that of Si. Based on the above results, we propose to assign those species of Strombomonas into Trachelomonas and consider them as a group of the latter. These species were the most primitive among the group with envelopes in Euglenaceae.
文摘The absence of low-frequency information in seismic data is one of the most difficult problems in elastic full waveform inversion. Without low-frequency data, it is difficult to recover the long-wavelength components of subsurface models and the inversion converges to local minima. To solve this problem, the elastic envelope inversion method is introduced. Based on the elastic envelope operator that is capable of retrieving low- frequency signals hidden in multicomponent data, the proposed method uses the envelope of multicomponent seismic signals to construct a misfit function and then recover the long- wavelength components of the subsurface model. Numerical tests verify that the elastic envelope method reduces the inversion nonlinearity and provides better starting models for the subsequent conventional elastic full waveform inversion and elastic depth migration, even when low frequencies are missing in multicomponent data and the starting model is far from the true model. Numerical tests also suggest that the proposed method is more effective in reconstructing the long-wavelength components of the S-wave velocity model. The inversion of synthetic data based on the Marmousi-2 model shows that the resolution of conventional elastic full waveform inversion improves after using the starting model obtained using the elastic envelope method. Finally, the limitations of the elastic envelope inversion method are discussed.
文摘As in homology, the notion of injectivity is introduced in the category whose objects are Hilbert C * module over a C * algebra and whose morphism are bounded module operators. The definition of injective envelopes of an extension of a Hilbert C * modules over a C * algebra is introduced, and is characterized in terms of the injectivity and essence. It is shown that every Hilbert C * module has a unique (up to H isometrics) injective envelope if it exists. It is also shown that an extension of a Hilbert C * module is an injective envelope if and only if it is an injective and essential extension. Moreover, every Hilbert C * module over a W * algebra has a unique (up to H isometrics) injective envelope and the injective envelope of a Hilbert C * module H is maximal essential extension of H .
文摘The Shipboard Operation Envelope(SOE) is the safe boundary of the helicopter/ship dynamic interface. The night deck on a ship is usually behind the hangar, where the airflow is turbulent due to the influence of the upper structure, wind and ship speed. The turbulent airnow is the major adverse factor for the safety of shipboard operations. In this paper, the night deck abbot is analysed as the superposition of two penyndicular 2-D airflows.N-S equations are used to calculate the velocity field and the range of turbulent airflow using finite element method. The result is correspondent well with test. Incorporating the influence of the airflow and giving some restrictions on the movements of the ship and on the control margin of the helicopter, the operation envelopes are calculated. The operation envelopes include three types for hovering over the deck, taking-off from and landing on ship, and landing with a landing-aid system. These results are helpful to the pilot training and night safety.
基金Supported by National Natural Science Foundation of China(Grant Nos.51175316,51575331)
文摘The vibration signal contains a wealth of sensitive information which reflects the running status of the equipment. It is one of the most important steps for precise diagnosis to decompose the signal and extracts the effective information properly. The traditional classical adaptive signal decomposition method, such as EMD, exists the problems of mode mixing, low decomposition accuracy etc. Aiming at those problems, EAED(extreme average envelope decomposition) method is presented based on EMD. EAED method has three advantages. Firstly, it is completed through midpoint envelopment method rather than using maximum and minimum envelopment respectively as used in EMD. Therefore, the average variability of the signal can be described accurately. Secondly, in order to reduce the envelope errors during the signal decomposition, replacing two envelopes with one envelope strategy is presented. Thirdly, the similar triangle principle is utilized to calculate the time of extreme average points accurately. Thus, the influence of sampling frequency on the calculation results can be significantly reduced. Experimental results show that EAED could separate out single frequency components from a complex signal gradually. EAED could not only isolate three kinds of typical bearing fault characteristic of vibration frequency components but also has fewer decomposition layers. EAED replaces quadratic enveloping to an envelope which ensuring to isolate the fault characteristic frequency under the condition of less decomposition layers. Therefore, the precision of signal decomposition is improved.
基金supported by the National High Technology Researchand Development Program of China (863 Program) (YJCB2008023WL)
文摘Efficiency and linearity of the microwave power amplifier are critical elements for mobile communication systems. A memory polynomial baseband predistorter based on an indirect learning architecture is presented for improving the linearity of an envelope tracing (ET) amplifier with application to a wireless transmitter. To deal with large peak-to-average ratio (PAR) problem, a clipping procedure for the input signal is employed. Then the system performance is verified by simulation results. For a single carrier wideband code division multiple access (WCDMA) signal of 16-quadrature amplitude modulation (16-QAM), about 2% improvement of the error vector magnitude (EVM) is achieved at an average output power of 45.5 dBm and gain of 10.6 dB, with adjacent channel leakage ratio (ACLR) of -64.55 dBc at offset frequency of 5 MHz. Moreover, a three-carrier WCDMA signal and a third-generation (3G) long term evolution (LTE) signal are used as test signals to demonstrate the performance of the proposed linearization scheme under different bandwidth signals.
文摘Hepatitis B virus(HBV),a major cause of human liver disease worldwide,encodes three envelope proteins needed for the attachment and entry of the virus into susceptible host cells.A second virus,hepatitis delta virus,which is known to enhance liver disease in HBV infected patients,diverts the same HBV envelope proteins to achieve its own assembly and infection.In the lab,lentiviral vectors based on human immunodeficiency virus type 1 can be assembled using the HBV envelope proteins,and will similarly infect susceptible cells.This article provides a partial review and some personal reflections of how these three viruses infect and of how recipient cells become susceptible,along with some consideration of questions that remain to be answered.
基金the Foundation for University Key Teacher by the Ministry of Education.
文摘A simple shallow-water model on an equatorial β-plane is employed to investigate the nonlinear equatorial Rossby solitons in a mean zonal flow with meridional shear by the asymptotic method of multiple scales. The cubic nonlinear Schr?dinger (NLS, for short) equation, satisfied for large amplitude equatorial envelope Rossby solitons in shear basic flow, is derived. The effects of basic flow shear on the nonlinear equatorial Rossby solitons are also analyzed. Key words Envelope solitons - NLS This work was supported by the Foundation for University Key Teacher by the Ministry of Education.
文摘Constant envelope with a fractional Fourier transformorthogonal frequency division multiplexing(CE-FrFT-OFDM)is a special case of a constant envelope OFDM(CE-OFDM),both being energy efficient wireless communication techniques with a 0 dB peak to average power ratio(PAPR).However,with the proper selection of fractional order,the first technique has a high bit error rate(BER)performance in the frequency-time selective channels.This paper performs further analysis of CE-FrFT-OFDM by examining its spectral efficiency(SE)and energy efficiency(EE)and compare to the famous OFDM and FrFT-OFDM techniques.Analytical and comprehensive simulations conducted show that,the CE-FrFT-OFDM has five times the EE of OFDM and FrFT-OFDM systems with a slightly less SE.Increasing CE-FrFT-OFDM’s transmission power by increasing its amplitude to 1.7 increases its SE to match that of the OFDM and FrFT-OFDM systems while slightly reducing its EE by 20%to be four times that of OFDM and FrFTOFDM systems.OFDM and FrFT-OFDM’s amplitude fluctuations cause rapid changing output back-off(OBO)power requirements and further reduce power amplifier(PA)efficiency while CE-FrFTOFDM stable operational linear range makes it a better candidate and outperforms the other techniques when their OBO exceeds 1.7.Higher EE and low BER in time-frequency selective channel are attracting features for CE-FrFT-OFDM deployment in mobile devices.
文摘The cylindrical worm processed by annular grinding wheel envelope in two degree of freedom motion state is a novel worm. This paper explains the shaping principle of such a worm. To improve meshing quality and the properties of contact and lubrication, the multi objective optimization has been conducted for the first time to the parameters of such a worm pair by the fuzzy optimal method. The results show that, the shape of the contact line is visibly more sloped than before being optimized, lubrication angle is apparently bigger, and the distribution of contact lines is much improved.
基金This work was financially supported by National Key R&D Program of China(2022YFD1401200)China Agriculture Research System of MOF and MARA(CARS-24-C-04)+3 种基金National Natural Science Foundation of China(32270294)Ningbo Major Special Projects of the Plan‘Science and Technology Innovation 2025’(2021Z106)the Postdoctoral Science Foundation of Anhui Province,China(2021B558)K.C.Wong Magna Fund in Ningbo University.
文摘Pepper mild mottle virus(PMMoV)is a devastating viral pathogen of pepper(Capsicum annuum)but it is unclear whether and how peppers protect against PMMoV infection.The expression of the chloroplast outer membrane protein 24(OMP24)of C.annuum was upregulated under PMMoV infection and it interacted with PMMoV coat protein(CP).Silencing of OMP24 in either C.annuum or Nicotiana benthamiana facilitated PMMoV infection,whereas overexpression of N.benthamiana OMP24 in transgenic plants inhibited PMMoV infection.Both C.annuum OMP24(CaOMP24)and N.benthamiana OMP24(NbOMP24)localized to the chloroplast and have a moderately hydrophobic transmembrane domain that is necessary for their localization.Overexpression of CaOMP24 induced stromules,perinuclear chloroplast clustering,and accumulation of reactive oxygen species(ROS),the typical defense responses of chloroplasts transferring the retrograde signaling to the nucleus to regulate resistance genes.The expression of PR1 and PR2 was also upregulated significantly in plants overexpressing OMP24.Self-interaction of OMP24 was demonstrated and was required for OMP24-mediated plant defense.Interaction with PMMoV CP interfered with the self-interaction of OMP24 and impaired OMP24-induced stromules,perinuclear chloroplast clustering and ROS accumulation.The results demonstrate the defense function of OMP24 in pepper during viral infection and suggest a possible mechanism by which PMMoV CP modulates the plant defense to facilitate viral infection.
基金supported by grants from National Science and Technology Major Project(2012ZX10004701)
文摘The CD4 binding site(CD4bs) of envelope glycoprotein(Env) is an important conserved target for anti-human immunodeficiency virus type 1(HIV-1) neutralizing antibodies. Neutralizing monoclonal antibodies IgG1 b12(b12) could recognize conformational epitopes that overlap the CD4 bs of Env. Different virus strains, even derived from the same individual, showed distinct neutralization susceptibility to b12. We examined the key amino acid residues affecting b12 neutralization susceptibility using single genome amplification and pseudovirus neutralization assay. Eleven amino acid residues were identified that affect the sensitivity of Env to b12. Through site-directed mutagenesis, an amino acid substitution at position 182 in the V2 region of Env was confirmed to play a key role in regulating the b12 neutralization susceptibility. The introduction of V182 L to a resistant strain enhanced its sensitivity to b12 more than twofold. Correspondingly, the introduction of L182 V to a sensitive strain reduced its sensitivity to b12 more than tenfold. Amino acid substitution at positions 267 and 346 could both enhance the sensitivity to b12 more than twofold. However, no additive effect was observed when the three site mutageneses were introduced into the same strain, and the sensitivity was equivalent to the single V182 L mutation. CRF07_BC is a major circulating recombinant form of HIV-1 prevalent in China. Our data may provide important information for understanding the molecular mechanism regulating the neutralization susceptibility of CRF07_BC viruses to b12 and may be helpful for a vaccine design targeting the CD4 bs epitopes.
基金supported by the State Key Program of National Natural Science of China (No. 11232009)the Shanghai Leading Academic Discipline Project (No. S30106)
文摘One of the important issues in the system identification and the spectrum analysis is the frequency resolution, i.e., the capability of distinguishing between two or more closely spaced frequency components. In the modal identification by the empirical mode decomposition (EMD) method, because of the separating capability of the method, it is still a challenge to consistently and reliably identify the parameters of structures of which modes are not well separated. A new method is introduced to generate the intrin- sic mode functions (IMFs) through the filtering algorithm based on the wavelet packet decomposition (GIFWPD). In this paper, it is demonstrated that the CIFWPD method alone has a good capability of separating close modes, even under the severe condition beyond the critical frequency ratio limit which makes it impossible to separate two closely spaced harmonics by the EMD method. However, the GIFWPD-only based method is impelled to use a very fine sampling frequency with consequent prohibitive computational costs. Therefore, in order to decrease the computational load by reducing the amount of samples and improve the effectiveness of separation by increasing the frequency ratio, the present paper uses a combination of the complex envelope displacement analysis (CEDA) and the GIFWPD method. For the validation, two examples from the previous works are taken to show the results obtained by the GIFWPD-only based method and by combining the CEDA with the GIFWPD method.
基金supported by the National Science Foundation(Grant No.41104069,41274124)National“973 Project”(Grant No.2014CB239006)+1 种基金National Oil and Gas Project(Grant No.2016ZX05014001,2016ZX05002)supported by Tai Shan Science Foundation for the Excellent Youth Scholars.
文摘Envelope inversion(El)is an efficient tool to mitigate the nonlinearity of conventional full waveform inversion(FWI)by utilizing the ultralow-frequency component in the seismic data.However,the performance of envelope inversion depends on the frequency component and initial model to some extent.To improve the convergence ability and avoid the local minima issue,we propose a convolution-based envelope inversion method to update the low-wavenumber component of the velocity model.Besides,the multi-scale inversion strategy(MCEI)is also incorporated to improve the inversion accuracy while guaranteeing the global convergence.The success of this method relies on modifying the original envelope data to expand the overlap region between observed and modeled envelope data,which in turn expands the global minimum basin of misfit function.The accurate low-wavenumber component of the velocity model provided by MCEI can be used as the migration model or an initial model for conventional FWI.The numerical tests on simple layer model and complex BP 2004 model verify that the proposed method is more robust than El even when the initial model is coarse and the frequency component of data is high.
基金Funded by the Fundamental Research Funds for the Central Universities(No.HIT.KISTP.201408)
文摘This study aimed to investigate the effect of artificial weathering test on the photoaging behavior of TPU films. Changes in mechanical properties, morphology and chemical structures are studied by tensile test, scanning electron microscopy, atomic force microscopy, Fourier-transformed infrared, and X-ray photoelectron spectroscopy. The results show that the photoaging negatively affects the initial modulus and stress at break values of TPU films. The surface of the specimen that is exposed to irradiation becomes rough, and some visible micro-defects such as blisters and voids can be detected. The morphology of the fracture surfaces illustrates that irradiation reduces the plasticity but increases the brittleness of the TPU films. The chemical structure analyses of the accelerated aged films prove that chemical structural changes in TPU films occur. The irradiation may break the long molecular chains on the surface of the specimens and form the lowmolecular weight oxygen-containing groups. The number of chain scissions increases with the increase in exposure time.