类黄杞属(Palaeocarya Saporta,1873,emend.Manchester,1987)隶属于胡桃科,是一个化石属,典型特征为翅果具有三裂片。该属的化石记录非常丰富,在北半球的新生代地层中被广泛报道。在中国,类黄杞属的化石记录主要见于海南、广西、吉林和...类黄杞属(Palaeocarya Saporta,1873,emend.Manchester,1987)隶属于胡桃科,是一个化石属,典型特征为翅果具有三裂片。该属的化石记录非常丰富,在北半球的新生代地层中被广泛报道。在中国,类黄杞属的化石记录主要见于海南、广西、吉林和云南。本文描述了发现于广东茂名盆地晚始新世和早渐新世地层中的类黄杞属果化石4种,分别为:Palaeocarya yunnanensis San-Ping Xie et Bai-Nian Sun,P.guangxiensis Li et Chen Y.F.,P.gaolingensis Yun-Fa Chen,P.hispida H.H.Meng et Z.K.Zhou。这是迄今广东首次发现类黄杞属大化石,表明在晚始新世时类黄杞属植物即已分布到我国低纬度亚热带地区,并开始了多样性的演化。展开更多
Pterocarine (1), a new diarylheptanoidal compound, was isolated from Pterocaryatonkinesis (Franch.) Dode. together with a known diarylheptanoid, myricatomentogenin (2), througha bioassay-guided fractionation procedure...Pterocarine (1), a new diarylheptanoidal compound, was isolated from Pterocaryatonkinesis (Franch.) Dode. together with a known diarylheptanoid, myricatomentogenin (2), througha bioassay-guided fractionation procedure. The structure of 1 was elucidated as (+)-3', 4''-epoxy-1-(4'-hydroxyphenyl)-7-(3''-hydroxyphenyl)-heptane-3-one by the spectroscopic methods.Pterocarine (1) inhibited the proliferation of tsFT210, HCT-15 and K562 cells with the inhibitionrates of 20.2±2.4, 23.8±2.4 and 50.5±1.2% at 100 μg/mL, respectively. Flow cytometric analysisindicated that 1 could inhibit the cell cycle of tsFT210, HCT-15 and K562 cells at the G0/G1 phaseand could also induce apoptosis in HCT-15 (19%) and K562 (11%) cells.展开更多
A new compound, 4-hydroxy-a-tetralone-4-O-b-D-[6-O-(3,4,5-trihydroxybenzoyl) glucopyranoside (1), together with a known compound, 4-hydroxy-a-tetralone (2), has been isolated from the roots of Juglans regia. 2 showed...A new compound, 4-hydroxy-a-tetralone-4-O-b-D-[6-O-(3,4,5-trihydroxybenzoyl) glucopyranoside (1), together with a known compound, 4-hydroxy-a-tetralone (2), has been isolated from the roots of Juglans regia. 2 showed moderate bioactivity against protein tyrosine phosphatase 1B (PTP1B).展开更多
采用柱色谱、重结晶等方法从核桃青皮Walnut green husk进行分离得到13个化合物,利用现代波谱学方法鉴定了它们的结构,分别鉴定为3,5-二甲氧基-4-羟基-苯甲酸-7-O-β-D-葡萄糖苷(1)、myricananin F(2)、β-谷甾醇(3)、齐墩果酸(4)、核桃...采用柱色谱、重结晶等方法从核桃青皮Walnut green husk进行分离得到13个化合物,利用现代波谱学方法鉴定了它们的结构,分别鉴定为3,5-二甲氧基-4-羟基-苯甲酸-7-O-β-D-葡萄糖苷(1)、myricananin F(2)、β-谷甾醇(3)、齐墩果酸(4)、核桃酮(5)、积雪草酸(6)、常春藤皂苷元(7)、β-胡萝卜苷(8)、(4R)-4,8-二羟基-α-四氢萘酮-4-O-β-D-吡喃葡萄糖苷(9)、3β,23-二羟基-12-烯-28-乌苏酸(10)、熊果酸(11)、丁香酸(12)、Juglanoside B(13)。其中,化合物1、2、6、7、9、10均为首次从该属植物中分离得到。经体外抗肿瘤活性筛选,发现化合物4对人肝癌细胞(Hep G-2)的增殖显示了较强的生长抑制活性,化合物9对人乳腺癌细胞(MCF-7)的增殖具有一定的生长抑制活性。展开更多
文摘类黄杞属(Palaeocarya Saporta,1873,emend.Manchester,1987)隶属于胡桃科,是一个化石属,典型特征为翅果具有三裂片。该属的化石记录非常丰富,在北半球的新生代地层中被广泛报道。在中国,类黄杞属的化石记录主要见于海南、广西、吉林和云南。本文描述了发现于广东茂名盆地晚始新世和早渐新世地层中的类黄杞属果化石4种,分别为:Palaeocarya yunnanensis San-Ping Xie et Bai-Nian Sun,P.guangxiensis Li et Chen Y.F.,P.gaolingensis Yun-Fa Chen,P.hispida H.H.Meng et Z.K.Zhou。这是迄今广东首次发现类黄杞属大化石,表明在晚始新世时类黄杞属植物即已分布到我国低纬度亚热带地区,并开始了多样性的演化。
基金This work was supported by the Fund from the National Natural Science Foundation of China(C.-B.CUI,No.39825126)the Fund for the 973-project from Ministry of Science and Technology(C.-B.CUI,No.1998051113),Chinathe Fund for Cheung Kong Scholar(C.B.CUI)from Cheung Kong Scholars Program,Ministry of Education of China.
文摘Pterocarine (1), a new diarylheptanoidal compound, was isolated from Pterocaryatonkinesis (Franch.) Dode. together with a known diarylheptanoid, myricatomentogenin (2), througha bioassay-guided fractionation procedure. The structure of 1 was elucidated as (+)-3', 4''-epoxy-1-(4'-hydroxyphenyl)-7-(3''-hydroxyphenyl)-heptane-3-one by the spectroscopic methods.Pterocarine (1) inhibited the proliferation of tsFT210, HCT-15 and K562 cells with the inhibitionrates of 20.2±2.4, 23.8±2.4 and 50.5±1.2% at 100 μg/mL, respectively. Flow cytometric analysisindicated that 1 could inhibit the cell cycle of tsFT210, HCT-15 and K562 cells at the G0/G1 phaseand could also induce apoptosis in HCT-15 (19%) and K562 (11%) cells.
文摘A new compound, 4-hydroxy-a-tetralone-4-O-b-D-[6-O-(3,4,5-trihydroxybenzoyl) glucopyranoside (1), together with a known compound, 4-hydroxy-a-tetralone (2), has been isolated from the roots of Juglans regia. 2 showed moderate bioactivity against protein tyrosine phosphatase 1B (PTP1B).
