Dynamic Interaction Analysis of Coupled Axial-Torsional-Lateral Mechanical Vibrations in Rotary Drilling Systems

Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emphasis on structural durability and monitoring is required.This study focuses on the mechanical vibrations that occur in rotary drilling systems,which have a substantial impact on the structural integrity of drilling equipment.The study specifically investigates axial,torsional,and lateral vibrations,which might lead to negative consequences such as bit-bounce,chaotic whirling,and high-frequency stick-slip.These events not only hinder the efficiency of drilling but also lead to exhaustion and harm to the system’s components since they are difficult to be detected and controlled in real time.The study investigates the dynamic interactions of these vibrations,specifically in their high-frequency modes,usingfield data obtained from measurement while drilling.Thefindings have demonstrated the effect of strong coupling between the high-frequency modes of these vibrations on drilling sys-tem performance.The obtained results highlight the importance of considering the interconnected impacts of these vibrations when designing and implementing robust control systems.Therefore,integrating these compo-nents can increase the durability of drill bits and drill strings,as well as improve the ability to monitor and detect damage.Moreover,by exploiting thesefindings,the assessment of structural resilience in rotary drilling systems can be enhanced.Furthermore,the study demonstrates the capacity of structural health monitoring to improve the quality,dependability,and efficiency of rotary drilling systems in the petroleum industry.

Research status and prospects of the fractal analysis of metal material surfaces and interfaces

As a mathematical analysis method,fractal analysis can be used to quantitatively describe irregular shapes with self-similar or self-affine properties.Fractal analysis has been used to characterize the shapes of metal materials at various scales and dimensions.Conventional methods make it difficult to quantitatively describe the relationship between the regular characteristics and properties of metal material surfaces and interfaces.However,fractal analysis can be used to quantitatively describe the shape characteristics of metal materials and to establish the quantitative relationships between the shape characteristics and various properties of metal materials.From the perspective of two-dimensional planes and three-dimensional curved surfaces,this paper reviews the current research status of the fractal analysis of metal precipitate interfaces,metal grain boundary interfaces,metal-deposited film surfaces,metal fracture surfaces,metal machined surfaces,and metal wear surfaces.The relationship between the fractal dimensions and properties of metal material surfaces and interfaces is summarized.Starting from three perspectives of fractal analysis,namely,research scope,image acquisition methods,and calculation methods,this paper identifies the direction of research on fractal analysis of metal material surfaces and interfaces that need to be developed.It is believed that revealing the deep influence mechanism between the fractal dimensions and properties of metal material surfaces and interfaces will be the key research direction of the fractal analysis of metal materials in the future.

Antioxidant and lipoxygenase inhibitory properties of a novel flavonoid from Pistacia chinensis Bunge and its molecular docking analysis

Background:Pistacia chinensis Bunge has been traditionally used to manage various conditions,including asthma,pain,inflammation,hepatoprotection,and diabetes.The study was conducted to investigate the antioxidant and anti-lipoxygenase(LOX)properties of the isolated compound 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one from Pistacia chinensis.Methods:LOX assay and antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl(DPPH)assay were performed.Molecular docking studies were conducted using a molecular operating environment.Results:The LOX assay revealed significant inhibitory effects at 0.2µM concentration,with an IC50 value of 37.80µM.The antioxidant effect demonstrated dose-dependency across 5 to 100µg/mL concentrations,reaching 93.09%at 100µg/mL,comparable to ascorbic acid’s 95.43%effect.Molecular docking studies highlighted strong interactions with the lipoxygenase enzyme,presenting an excellent docking score of-10.98 kcal/mol.Conclusion:These findings provide valuable insights into Pistacia chinensis’chemical components and biological effects,reinforcing its traditional medicinal applications.

Prenatal ultrasonography and genetic analysis of fetal cleidocranial dysplasia:A case report

BACKGROUND Cleidocranial dysplasia(CCD)is an infrequent clinical condition with an autosomal dominant inheritance pattern.It is characterized by abnormal clavicles,patent sutures and fontanelles,supernumerary teeth,and short stature.Approximately 60%-70%of patients with CCD have mutations in the RUNX family transcription factor 2 gene.However,prenatal diagnosis of CCD is difficult when the family history is unknown.CASE SUMMARY We report a rare case of fetal CCD with an unknown family history,confirmed by prenatal ultrasonography and genetic testing at a gestational age of 16 weeks.The genetic reports indicated that the fetus carried pathogenic mutations in the RUNX family transcription factor 2 gene(c.674G>A).After careful consideration,the pregnant woman and her family decided to continue the pregnancy.CONCLUSION Definitive prenatal diagnosis of CCD should include family history,ultrasound diagnosis,and genetic analysis,especially if family history is unknown.

Retrospective analysis of pathological types and imaging features in pancreatic cancer: A comprehensive study

BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features is crucial for early detection and appropriate treatment planning.AIM To retrospectively analyze the relationship between different pathological types of pancreatic cancer and their corresponding imaging features.METHODS We retrospectively analyzed the data of 500 patients diagnosed with pancreatic cancer between January 2010 and December 2020 at our institution.Pathological types were determined by histopathological examination of the surgical spe-cimens or biopsy samples.The imaging features were assessed using computed tomography,magnetic resonance imaging,and endoscopic ultrasound.Statistical analyses were performed to identify significant associations between pathological types and specific imaging characteristics.RESULTS There were 320(64%)cases of pancreatic ductal adenocarcinoma,75(15%)of intraductal papillary mucinous neoplasms,50(10%)of neuroendocrine tumors,and 55(11%)of other rare types.Distinct imaging features were identified in each pathological type.Pancreatic ductal adenocarcinoma typically presents as a hypodense mass with poorly defined borders on computed tomography,whereas intraductal papillary mucinous neoplasms present as characteristic cystic lesions with mural nodules.Neuroendocrine tumors often appear as hypervascular lesions in contrast-enhanced imaging.Statistical analysis revealed significant correlations between specific imaging features and pathological types(P<0.001).CONCLUSION This study demonstrated a strong association between the pathological types of pancreatic cancer and imaging features.These findings can enhance the accuracy of noninvasive diagnosis and guide personalized treatment approaches.

Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions

BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of global research on BD drug treatment over the last decade.METHODS The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were extracted.Data visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks.The University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this field.The Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited paper.CONCLUSION This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future directions.The study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.

Targeted gene sequencing and bioinformatics analysis of patients with gallbladder neuroendocrine carcinoma:A case report

BACKGROUND Gallbladder neuroendocrine carcinoma(NEC)represents a subtype of gallbladder malignancies characterized by a low incidence,aggressive nature,and poor prognosis.Despite its clinical severity,the genetic alterations,mechanisms,and signaling pathways underlying gallbladder NEC remain unclear.CASE SUMMARY This case study presents a rare instance of primary gallbladder NEC in a 73-year-old female patient,who underwent a radical cholecystectomy with hepatic hilar lymphadenectomy and resection of liver segments IV-B and V.Targeted gene sequencing and bioinformatics analysis tools,including STRING,GeneMANIA,Metascape,TRRUST,Sangerbox,cBioPortal and GSCA,were used to analyze the biological functions and features of mutated genes in gallbladder NEC.Twelve mutations(APC,ARID2,IFNA6,KEAP1,RB1,SMAD4,TP53,BTK,GATA1,GNAS,and PRDM3)were identified,and the tumor mutation burden was determined to be 9.52 muts/Mb via targeted gene sequencing.A protein-protein interaction network showed significant interactions among the twelve mutated genes.Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were used to assess mutation functions and pathways.The results revealed 40 tumor-related pathways.A key regulatory factor for gallbladder NEC-related genes was identified,and its biological functions and features were compared with those of gallbladder carcinoma.CONCLUSION Gallbladder NEC requires standardized treatment.Comparisons with other gallbladder carcinomas revealed clinical phenotypes,molecular alterations,functional characteristics,and enriched pathways.

Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and disabilities.Research on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target organs.This has led to restrictions on current therapeutic approaches.In this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target organs.After peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal cord.The nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury site.Corresponding damage to target organs can occur,including skeletal muscle atrophy and sensory receptor disruption.We then provide a brief review of the research advances in therapeutic approaches to peripheral nerve injury.The main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical exercise.However,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ pathway.Therefore,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

Optimization of constitutive parameters of foundation soils k-means clustering analysis

The goal of this study was to optimize the constitutive parameters of foundation soils using a k-means algorithm with clustering analysis. A database was collected from unconfined compression tests, Proctor tests and grain distribution tests of soils taken from three different types of foundation pits： raft foundations, partial raft foundations and strip foundations. k-means algorithm with clustering analysis was applied to determine the most appropriate foundation type given the un- confined compression strengths and other parameters of the different soils.

Polarimetric Meteorological Satellite Data Processing Software Classification Based on Principal Component Analysis and Improved K-Means Algorithm

With the increasing variety of application software of meteorological satellite ground system, how to provide reasonable hardware resources and improve the efficiency of software is paid more and more attention. In this paper, a set of software classification method based on software operating characteristics is proposed. The method uses software run-time resource consumption to describe the software running characteristics. Firstly, principal component analysis (PCA) is used to reduce the dimension of software running feature data and to interpret software characteristic information. Then the modified K-means algorithm was used to classify the meteorological data processing software. Finally, it combined with the results of principal component analysis to explain the significance of various types of integrated software operating characteristics. And it is used as the basis for optimizing the allocation of software hardware resources and improving the efficiency of software operation.

Cluster analysis of polymers using laser-induced breakdown spectroscopy with K-means

Laser-induced breakdown spectroscopy（LIBS） combined with K-means algorithm was employed to automatically differentiate industrial polymers under atmospheric conditions.The unsupervised learning algorithm K-means were utilized for the clustering of LIBS dataset measured from twenty kinds of industrial polymers.To prevent the interference from metallic elements,three atomic emission lines（C I 247.86 nm,H I 656.3 nm,and O I 777.3 nm） and one molecular line C–N（0,0） 388.3 nm were used.The cluster analysis results were obtained through an iterative process.The Davies–Bouldin index was employed to determine the initial number of clusters.The average relative standard deviation values of characteristic spectral lines were used as the iterative criterion.With the proposed approach,the classification accuracy for twenty kinds of industrial polymers achieved 99.6%.The results demonstrated that this approach has great potential for industrial polymers recycling by LIBS.

A State of Art Analysis of Telecommunication Data by k-Means and k-Medoids Clustering Algorithms

Cluster analysis is one of the major data analysis methods widely used for many practical applications in emerging areas of data mining. A good clustering method will produce high quality clusters with high intra-cluster similarity and low inter-cluster similarity. Clustering techniques are applied in different domains to predict future trends of available data and its uses for the real world. This research work is carried out to find the performance of two of the most delegated, partition based clustering algorithms namely k-Means and k-Medoids. A state of art analysis of these two algorithms is implemented and performance is analyzed based on their clustering result quality by means of its execution time and other components. Telecommunication data is the source data for this analysis. The connection oriented broadband data is given as input to find the clustering quality of the algorithms. Distance between the server locations and their connection is considered for clustering. Execution time for each algorithm is analyzed and the results are compared with one another. Results found in comparison study are satisfactory for the chosen application.

Multiple Parameter Based Clustering (MPC): Prospective Analysis for Effective Clustering in Wireless Sensor Network (WSN) Using K-Means Algorithm

In wireless sensor network cluster architecture is useful because of its inherent suitability for data fusion. In this paper we represent a new approach called Multiple Parameter based Clustering (MPC) embedded with the traditional k-means algorithm which takes different parameters (Node energy level, Euclidian distance from the base station, RSSI, Latency of data to reach base station) into consideration to form clusters. Then the effectiveness of the clusters is evaluated based on the uniformity of the node distribution, Node range per cluster, Intra and Inter cluster distance and required energy level of each centroid. Our result shows that by varying multiple parameters we can create clusters with more uniformly distributed nodes, minimize intra and maximize inter cluster distance and elect less power consuming centroid.

A Study on the Online Teaching Input of Higher Education Teachers Based on K-Means Analysis

Online teaching has become an important form of regular teaching in higher education institutions,and teachers’input in online teaching is directly related to the quality of online teaching.A K-means cluster analysis of teachers’teaching behaviours in the online teaching platform of Sanya Aviation and Tourism College and a comparison of the mean values of each semester’s behaviours reveal that teachers’overall online teaching input is insufficient and their online teaching behaviours need to be optimized;their teaching energy has improved and their online teaching resources are more completed;their teaching emotional input is seriously lacking and their online interaction needs to be strengthened.To address these problems,the following measures can be taken:improve teachers’incentives to increase the overall investment in online teaching;change teachers’roles to strengthen the emotional investment in online teaching;and strengthen teachers’training to enhance online teaching design skills.

基于改进K-means聚类的轨道交通基础设施分布式光伏发电典型场景生成及出力特性分析

受限于自然条件,光伏出力具有很强的随机性。为准确评估轨道交通基础设施分布式光伏发电的光伏出力特性,提出一种基于改进K-means聚类算法的轨道交通基础设施分布式光伏发电典型场景生成方法,并基于此进行光伏出力特性分析。首先,基于分布式光伏发电设施以及气象数据,利用PVsyst软件模拟光伏发电出力数据。然后,针对基本K-means聚类算法聚类参数和初始聚类中心盲目性高的问题,结合聚类有效性指标(Density based index,DBI)和层次聚类对其进行改进并利用改进K-means聚类算法生成光伏典型日出力场景。最后,基于华中地区某地轨道交通基础设施分布式光伏系统对所提方法的有效性和优越性进行验证,并通过定性和定量分析各典型场景的出力特性揭示轨道交通基础设施分布式光伏出力的规律和特点。

基于特征分箱和K-Means算法的用户行为分析方法

针对网购用户所产生的购物行为进行分析,首先通过数据处理构建客户关系管理模型(RFM模型),在此模型的基础上采用特征分箱法和K-Means聚类两种方法对用户进行细分,并对2种模型结果进行比较分析,讨论二者的差异性和具体的应用范围和意义.其中,基于特征分箱法的RFM模型将变量转化到相似的尺度上并将变量离散化,使得用户分类标签更加清晰,也可依据各类标签分类出不同类型的用户.K-Means算法通过轮廓系数评估聚类算法质量以至于选取最优K值.本文实验分析结果可为运营商提供更加可靠直观的数据,使得运营商可以根据不同用户的不同行为进行市场细分,进而进行精准营销和服务设置.

基于改进K-means与机器视觉的档案数据分析技术

为了提升医疗信息系统对健康档案数据的分析效率,文中采用图像采集、降噪、配准与差分等技术提取医疗图像信息,进而有效提升信息系统的数据采集效率。同时还对传统的K-means算法加以改进,并提出了一种基于类间、类内距离的聚类初始化评价指标体系(BWP),将其应用于采集到的档案数据中,以实现快速的聚类分析。将所提算法在CUDA计算平台上进行了实现,测试结果表明,该方法的聚类精度和运行效率较现有算法均有显著提升。此外,改进后K-means算法的正确聚类样本数量占比提升了4.88%,高于现有的主流指标体系,且当聚类数k的取值为16或32时,运行时间大幅降低。

Campus Economic Analysis Based on K-Means Clustering and Hotspot Mining

With the advent of the era of big data and the development and construction of smart campuses,the campus is gradually moving towards digitalization,networking and informationization.The campus card is an important part of the construction of a smart campus,and the massive data it generates can indirectly reflect the living conditions of students at school.In the face of the campus card,how to quickly and accurately obtain the information required by users from the massive data sets has become an urgent problem that needs to be solved.This paper proposes a data mining algorithm based on K-Means clustering and time series.It analyzes the consumption data of a college student’s card to deeply mine and analyze the daily life consumer behavior habits of students,and to make an accurate judgment on the specific life consumer behavior.The algorithm proposed in this paper provides a practical reference for the construction of smart campuses in universities,and has important theoretical and application values.

光伏波动平抑下改进K-means的电池储能动态分组控制策略

针对电池储能系统(battery energy storage system,BESS)进行光伏波动平抑时寿命损耗高及荷电状态(state of charge,SOC)一致性差的问题,提出了光伏波动平抑下改进K-means的BESS动态分组控制策略。首先,采用最小最大调度方法获取光伏并网指令。其次,设计了改进侏儒猫鼬优化算法(improved dwarf mongoose optimizer,IDMO),并利用它对传统K-means聚类算法进行改进,加快了聚类速度。接着,制定了电池单元动态分组原则,并根据电池单元SOC利用改进K-means将其分为3个电池组。然后,设计了基于充放电函数的电池单元SOC一致性功率分配方法,并据此提出BESS双层功率分配策略,上层确定电池组充放电顺序及指令,下层计算电池单元充放电指令。对所提策略进行仿真验证,结果表明,所设计的IDMO具有更高的寻优精度及更快的寻优速度。所提BESS平抑光伏波动策略在有效平抑波动的同时,降低了BESS运行寿命损耗并提高了电池单元SOC的均衡性。

加入跳跃连接的深度嵌入K-means聚类

现有的深度聚类算法大多采用对称的自编码器来提取高维数据的低维特征,但随着自编码器训练次数的不断增加,数据的低维特征空间在一定程度上发生了扭曲,这样得到的数据低维特征空间无法反映原始数据空间中潜在的聚类结构信息.为了解决上述问题,本文提出了一种新的深度嵌入K-means算法(SDEKC).首先,在低维特征提取阶段,在对称的卷积自编码器中相对应的编码器与解码器之间以一定的权重加入两个跳跃连接,以减弱解码器对编码器的编码要求同时突出卷积自编码器的编码能力,这样可以更好地保留原始数据空间中蕴含的聚类结构信息;其次,在聚类阶段,通过一个标准正交变换矩阵将低维数据空间转换为一个新的揭示聚类结构信息的空间;最后,本文以端到端的方式采用贪婪算法迭代优化数据的低维表示及其聚类,在6个真实数据集上验证了本文提出新算法的有效性.