We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and...We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.展开更多
Background:To validate the Catquest-9SF questionnaire in Italian,assess the change in visual disability with cataract surgery and determine the correlation between pre-operative Catquest-9SF scores and Lens Opacities ...Background:To validate the Catquest-9SF questionnaire in Italian,assess the change in visual disability with cataract surgery and determine the correlation between pre-operative Catquest-9SF scores and Lens Opacities Classification System(LOCS)III cataract grading.Methods:Prospective,questionnaire validation study.The Catquest-9SF questionnaire was forward and back translated and completed by 209 Italian patients before and three months following cataract surgery.Rasch analysis was used to assess its psychometric properties.Results:The Italian Catquest-9SF demonstrated ordered response categories,unidimensionality(item fit statistics range:0.73–1.34),adequate person separation(2.04),and no differential item functioning.Mistargeting was evident with a mean difference in item difficulty and person ability of 2.04 logits but improved with inclusion of pre-operative data only.There was a statistically significant(Friedman tests,p<0.001)median improvement in visual disability of 1.92,3.57,1.44 and 2.94 logits in patients undergoing first eye surgery with and without ocular comorbidity,and second eye surgery with and without ocular comorbidity respectively.There was no statistically significant difference in the improvements among the four groups(Kruskal-Wallis H test,X^(2)(3)=5.445,p=0.142).There was no correlation between Catquest-9SF scores and nuclear opalescence(r_(s)=0.049,p=0.478),nuclear colour(r_(s)=0.008,p=0.909),cortical(r_(s)=0.066,p=0.341),and posterior subcapsular components(r_(s)=0.048,p=0.494).Conclusions:The Italian Catquest-9SF demonstrated good psychometric properties and is suitable for use in Italian speaking patients.There were similar improvements in visual disability in patients undergoing first or second eye surgery,with or without ocular comorbidity.There was no correlation between pre-operative Catquest-9SF scores and LOCS III cataract grading.展开更多
目的:引进简明幸福与生活质量满意度问卷(Quality of Life Enjoyment and Satisfaction Ques-tionnaire,Short Form,Q-LES-Q-SF),评估其在中国精神障碍患者中的信效度和适用性。方法:在山东省精神卫生中心2007年7月-2008年1月的门诊和...目的:引进简明幸福与生活质量满意度问卷(Quality of Life Enjoyment and Satisfaction Ques-tionnaire,Short Form,Q-LES-Q-SF),评估其在中国精神障碍患者中的信效度和适用性。方法:在山东省精神卫生中心2007年7月-2008年1月的门诊和住院患者中,按照就诊或住院的先后顺序,选取385例符合《ICD-10精神与行为障碍分类》诊断标准的精神分裂症(n=193)和心境障碍患者(n=192);按1∶2的比例选取与其相匹配的健康对照者196例。对所有对象进行Q-LES-Q-SF初次测评,30天后进行重测,对原始测评结果进行信度分析。以世界卫生组织生活质量量表(World Health Organization Quality of Life,WHO-QOL-100)为效标变量评价患者和健康对照者效标效度并进行区分效度分析。结果:信度分析显示量表的Cronbacnα系数为0.920,重测信度为0.785。总量表评分与WHOQOL-100总分及6个领域和24个方面均具有较高的相关性(心境障碍,r=0.22～0.71;精神分裂症,r=0.24～0.70;健康对照,r=0.17～0.73;Ps<0.01)。精神分裂症组和心境障碍组患者的幸福与生活质量满意度总分及各条目分均低于健康对照组[如总分,(46.42±8.36)vs.(54.34±8.11),(46.20±10.12)vs.(54.34±8.11),Ps<0.01]。结论:简明幸福与生活质量满意度问卷在中国精神障碍患者中有较好的信效度,适用于精神障碍患者生活质量的量化评估。展开更多
文摘We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.
基金Colm McAlinden was funded in part from a grant from the European Society of Cataract and Refractive Surgeons(ESCRS).
文摘Background:To validate the Catquest-9SF questionnaire in Italian,assess the change in visual disability with cataract surgery and determine the correlation between pre-operative Catquest-9SF scores and Lens Opacities Classification System(LOCS)III cataract grading.Methods:Prospective,questionnaire validation study.The Catquest-9SF questionnaire was forward and back translated and completed by 209 Italian patients before and three months following cataract surgery.Rasch analysis was used to assess its psychometric properties.Results:The Italian Catquest-9SF demonstrated ordered response categories,unidimensionality(item fit statistics range:0.73–1.34),adequate person separation(2.04),and no differential item functioning.Mistargeting was evident with a mean difference in item difficulty and person ability of 2.04 logits but improved with inclusion of pre-operative data only.There was a statistically significant(Friedman tests,p<0.001)median improvement in visual disability of 1.92,3.57,1.44 and 2.94 logits in patients undergoing first eye surgery with and without ocular comorbidity,and second eye surgery with and without ocular comorbidity respectively.There was no statistically significant difference in the improvements among the four groups(Kruskal-Wallis H test,X^(2)(3)=5.445,p=0.142).There was no correlation between Catquest-9SF scores and nuclear opalescence(r_(s)=0.049,p=0.478),nuclear colour(r_(s)=0.008,p=0.909),cortical(r_(s)=0.066,p=0.341),and posterior subcapsular components(r_(s)=0.048,p=0.494).Conclusions:The Italian Catquest-9SF demonstrated good psychometric properties and is suitable for use in Italian speaking patients.There were similar improvements in visual disability in patients undergoing first or second eye surgery,with or without ocular comorbidity.There was no correlation between pre-operative Catquest-9SF scores and LOCS III cataract grading.
文摘目的:引进简明幸福与生活质量满意度问卷(Quality of Life Enjoyment and Satisfaction Ques-tionnaire,Short Form,Q-LES-Q-SF),评估其在中国精神障碍患者中的信效度和适用性。方法:在山东省精神卫生中心2007年7月-2008年1月的门诊和住院患者中,按照就诊或住院的先后顺序,选取385例符合《ICD-10精神与行为障碍分类》诊断标准的精神分裂症(n=193)和心境障碍患者(n=192);按1∶2的比例选取与其相匹配的健康对照者196例。对所有对象进行Q-LES-Q-SF初次测评,30天后进行重测,对原始测评结果进行信度分析。以世界卫生组织生活质量量表(World Health Organization Quality of Life,WHO-QOL-100)为效标变量评价患者和健康对照者效标效度并进行区分效度分析。结果:信度分析显示量表的Cronbacnα系数为0.920,重测信度为0.785。总量表评分与WHOQOL-100总分及6个领域和24个方面均具有较高的相关性(心境障碍,r=0.22～0.71;精神分裂症,r=0.24～0.70;健康对照,r=0.17～0.73;Ps<0.01)。精神分裂症组和心境障碍组患者的幸福与生活质量满意度总分及各条目分均低于健康对照组[如总分,(46.42±8.36)vs.(54.34±8.11),(46.20±10.12)vs.(54.34±8.11),Ps<0.01]。结论:简明幸福与生活质量满意度问卷在中国精神障碍患者中有较好的信效度,适用于精神障碍患者生活质量的量化评估。
