We implemented a 3-3-1 algorithm in order to provide safe and simple self-titration in patients who newly initiated BOT as well as who were already on BOT and evaluated its utility in clinical setting. A total of 46 p...We implemented a 3-3-1 algorithm in order to provide safe and simple self-titration in patients who newly initiated BOT as well as who were already on BOT and evaluated its utility in clinical setting. A total of 46 patients, 21 patients in the newly-initiated group and 25 patients in the existing BOT group performed dose adjustment using 3-3-1 algorithm. HbA1c was significantly improved 4 weeks after the initiation from 8.5% ± 1.2% at baseline to 7.3% ± 0.7% at the final evaluation (p 0.01, vs. Baseline). The average daily insulin units increased throughout the study period from 10.1 ± 6.7 at baseline to 14.6 ± 8.9 units at the final evaluation. Weight didn’t significantly change throughout the study (p = 0.12). The incidents of hypoglycemia were 0.8/month during the insulin dose self-adjustment period and 0.4/month during the follow-up period. The 3-3-1 algorithm using insulin glargine provided a safe and simple dose adjustment and demonstrated its utility in patients who were newly introduced to insulin treatment as well as who were already on BOT.展开更多
An algorithm for integrating the constitutive equations in thermal framework is presented, in which the plastic deformation gradient is chosen as the integration variable. Compared with the classic algorithm, a key fe...An algorithm for integrating the constitutive equations in thermal framework is presented, in which the plastic deformation gradient is chosen as the integration variable. Compared with the classic algorithm, a key feature of this new approach is that it can describe the finite deformation of crystals under thermal conditions. The obtained plastic deformation gradient contains not only plastic defor- mation but also thermal effects. The governing equation for the plastic deformation gradient is obtained based on ther- mal multiplicative decomposition of the total deformation gradient. An implicit method is used to integrate this evo- lution equation to ensure stability. Single crystal 1 100 aluminum is investigated to demonstrate practical applications of the model. The effects of anisotropic properties, time step, strain rate and temperature are calculated using this integration model.展开更多
In order to optimize the knapsack problem further, this paper proposes an innovative model based on dynamic expectation efficiency, and establishes a new optimization algorithm of 0-1 knapsack problem after analysis a...In order to optimize the knapsack problem further, this paper proposes an innovative model based on dynamic expectation efficiency, and establishes a new optimization algorithm of 0-1 knapsack problem after analysis and research. Through analyzing the study of 30 groups of 0-1 knapsack problem from discrete coefficient of the data, we can find that dynamic expectation model can solve the following two types of knapsack problem. Compared to artificial glowworm swam algorithm, the convergence speed of this algorithm is ten times as fast as that of artificial glowworm swam algorithm, and the storage space of this algorithm is one quarter that of artificial glowworm swam algorithm. To sum up, it can be widely used in practical problems.展开更多
Discrete choice models are widely used in multiple sectors such as transportation, health, energy, and marketing, etc., where the model estimation is usually carried out by using commercial software. Nonetheless, tail...Discrete choice models are widely used in multiple sectors such as transportation, health, energy, and marketing, etc., where the model estimation is usually carried out by using commercial software. Nonetheless, tailored computer codes offer modellers greater flexibility and control of unique modelling situation. Aligned with empirically tailored computing environment, this research discusses the relative performance of six different algorithms of a discrete choice model using three key performance measures： convergence time, number of iterations, and iteration time. The computer codes are developed by using Visual Basic Application （VBA）. Maximum likelihood function （MLF） is formulated and the mathematical relationships of gradient and Hessian matrix are analytically derived to carry out the estimation process. The estimated parameter values clearly suggest that convergence criterion and initial guessing of parameters are the two critical factors in determining the overall estimation performance of a custom-built discrete choice model.展开更多
Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed...Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed by adopting adaptive step length and improved update strategy of wolf pack. AIBWPA is applied to 10 classic 0-1 knapsack problems and compared with BWPA, DPSO, which proves that AIBWPA has higher optimization accuracy and better computational robustness. AIBWPA makes the parameters simple, protects the population diversity and enhances the global convergence.展开更多
The production cycle of open-cast coal mines generally in eludes drilling, blasting, loading, hauling and coal preparation activities. Individual optimization of these activities does not mean that the whole system is...The production cycle of open-cast coal mines generally in eludes drilling, blasting, loading, hauling and coal preparation activities. Individual optimization of these activities does not mean that the whole system is optimized. This paper proposes a cost model considering all activities in mining cycle and system-wide approach to minimize the total mining cost of bench production. Since the fragmentation size and blast-hole diameter are linked to all activities of mining system, they are considered as decision variables in the problem form ul at io n. The operatio n costs are then minimized by using the evolutionary algorithm. Moreover, the impact of the change in the explosive price, and the hourly unit cost of equipment on total mining cost is quantified by sensitivity analysis. A case study is implemented to demonstrate the developed model.展开更多
Using S-rough sets, this paper gives the concepts off-heredity knowledge and its heredity coefficient, and f-variation coefficient of knowledge; presents the theorem of f-attribute dependence of variation coefficient ...Using S-rough sets, this paper gives the concepts off-heredity knowledge and its heredity coefficient, and f-variation coefficient of knowledge; presents the theorem of f-attribute dependence of variation coefficient and the relation theorem of heredity-variation. The attribute dependence of f-variation coefficient and the relation of heredity-variation are important characteristics of S-rough sets. From such discussion, this paper puts forward the heredity mining off-knowledge and the algorithm of heredity mining, also gives its relative application.展开更多
The pressing bonding of steel plate with QTi3.5-3.5graphite slurry was studied. The relationship among preheating temperature of steel plate, preheating temperature of dies, solid fraction of QTi3.5-3.5graphite slurry...The pressing bonding of steel plate with QTi3.5-3.5graphite slurry was studied. The relationship among preheating temperature of steel plate, preheating temperature of dies, solid fraction of QTi3.5-3.5graphite slurry, and interfacial shear strength of bonding plate could be established with artificial neural networks perfectly. This model could be optimized with a genetic algorithm. The results show that the optimum bonding parameters are: 618℃ for preheating temperature of steel plate, 526℃ for preheating temperature of dies and 46.2% for solid fraction of QTi3.5-3.5graphite slurry, and the largest interfacial shear strength of bonding plate is 128.3 MPa.展开更多
As a key to improve the performance of the interbay automated material handling system （AMHS） in 300 mm semiconductor wafer fabrication system, the real- time overhead hoist transport （OHT） dispatching problem has...As a key to improve the performance of the interbay automated material handling system （AMHS） in 300 mm semiconductor wafer fabrication system, the real- time overhead hoist transport （OHT） dispatching problem has received much attention. This problem is first formu- lated as a special form of assignment problem and it is proved that more than one solution will be obtained by Hungarian algorithm simultaneously. Through proposing and strictly proving two propositions related to the char- acteristics of these solutions, a modified Hungarian algo- rithm is designed to distinguish these solutions. Finally, a new real-time OHT dispatching method is carefully designed by implementing the solution obtained by the modified Hungarian algorithm. The experimental results of discrete event simulations show that, compared with con- ventional Hungarian algorithm dispatching method, the proposed dispatching method that chooses the solution with the maximum variance respectively reduces on average 4 s of the average waiting time and average lead time of wafer lots, and its performance is rather stable in multiple dif- ferent scenarios of the interbay AMHS with different quantities of shortcuts. This research provides an efficient real-time OHT dispatching mechanism for the interbay AMHS with shortcuts and bypasses.展开更多
Optimization of antenna array pattern used in a spaceborne Synthetic Aperture Radar (SAR) system is considered in this study. A robust evolutionary algorithm, Non-dominated Sorting Genetic Algorithms (the improved NS...Optimization of antenna array pattern used in a spaceborne Synthetic Aperture Radar (SAR) system is considered in this study. A robust evolutionary algorithm, Non-dominated Sorting Genetic Algorithms (the improved NSGA-Ⅱ), is applied on a spaceborne SAR antenna pattern design. The system consists of two objective functions with two constraints. Pareto fronts are generated as a result of multi-objective optimization. After being validated by a test problem ZDT4, the algorithms are used to synthesize spaceborne SAR antenna radiation pattern. The good results with low Ambi- guity-to-Signal Ratio (ASR) and high directivity are obtained in the paper.展开更多
A 0-1 integer programming model for weekly fleet assignment was put forward based on linear network and weekly flight scheduling in China. In this model, the objective function is to maximize the total profit of fleet...A 0-1 integer programming model for weekly fleet assignment was put forward based on linear network and weekly flight scheduling in China. In this model, the objective function is to maximize the total profit of fleet assignment, subject to the constraints of coverage, aircraft flow balance, fleet size, aircraft availability, aircraft usage, flight restriction, aircraft seat capacity, and stopover. Then the branch-and-bound algorithm based on special ordered set was applied to solve the model. At last, a real- wofld case study on an airline with 5 fleets, 48 aircrafts and 1 786 flight legs indicated that the profit increase was ￥ 1 591276 one week and the running time was no more than 4 rain, which shows that the model and algorithm are fairly good for domestic airline.展开更多
To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexe...To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexes(average temperature,average moisture content,average retention rate of the total anthocyanin content,temperature contrast value,and moisture dispersion value)were investigated via the response surface method(RSM)and the artificial neural network(ANN)with genetic algorithm(GA).The results showed that the microwave intensity and drying time dominated the changes of evaluation indexes.Overall,the ANN model was superior to the RSM model with better estimation ability,and higher drying uniformity and anthocyanin retention rate were achieved for the ANN-GA model compared with RSM.The optimal parameters were microwave intensity of 5.53 W•g^(-1),air velocity of 1.22 m·s^(-1),and drying time of 5.85 min.This study might provide guidance for process optimization of microwave drying berry fruits.展开更多
文摘We implemented a 3-3-1 algorithm in order to provide safe and simple self-titration in patients who newly initiated BOT as well as who were already on BOT and evaluated its utility in clinical setting. A total of 46 patients, 21 patients in the newly-initiated group and 25 patients in the existing BOT group performed dose adjustment using 3-3-1 algorithm. HbA1c was significantly improved 4 weeks after the initiation from 8.5% ± 1.2% at baseline to 7.3% ± 0.7% at the final evaluation (p 0.01, vs. Baseline). The average daily insulin units increased throughout the study period from 10.1 ± 6.7 at baseline to 14.6 ± 8.9 units at the final evaluation. Weight didn’t significantly change throughout the study (p = 0.12). The incidents of hypoglycemia were 0.8/month during the insulin dose self-adjustment period and 0.4/month during the follow-up period. The 3-3-1 algorithm using insulin glargine provided a safe and simple dose adjustment and demonstrated its utility in patients who were newly introduced to insulin treatment as well as who were already on BOT.
基金supported by the Key Project of the National Natural Science Foundation of China(10932003)Project of Chinese National Programs for Fundamental Research and Development(2012CB619603 and 2010CB832700)"04" Great Project of Ministry of Industrialization and Information of China (2011ZX04001-21)
文摘An algorithm for integrating the constitutive equations in thermal framework is presented, in which the plastic deformation gradient is chosen as the integration variable. Compared with the classic algorithm, a key feature of this new approach is that it can describe the finite deformation of crystals under thermal conditions. The obtained plastic deformation gradient contains not only plastic defor- mation but also thermal effects. The governing equation for the plastic deformation gradient is obtained based on ther- mal multiplicative decomposition of the total deformation gradient. An implicit method is used to integrate this evo- lution equation to ensure stability. Single crystal 1 100 aluminum is investigated to demonstrate practical applications of the model. The effects of anisotropic properties, time step, strain rate and temperature are calculated using this integration model.
文摘In order to optimize the knapsack problem further, this paper proposes an innovative model based on dynamic expectation efficiency, and establishes a new optimization algorithm of 0-1 knapsack problem after analysis and research. Through analyzing the study of 30 groups of 0-1 knapsack problem from discrete coefficient of the data, we can find that dynamic expectation model can solve the following two types of knapsack problem. Compared to artificial glowworm swam algorithm, the convergence speed of this algorithm is ten times as fast as that of artificial glowworm swam algorithm, and the storage space of this algorithm is one quarter that of artificial glowworm swam algorithm. To sum up, it can be widely used in practical problems.
文摘Discrete choice models are widely used in multiple sectors such as transportation, health, energy, and marketing, etc., where the model estimation is usually carried out by using commercial software. Nonetheless, tailored computer codes offer modellers greater flexibility and control of unique modelling situation. Aligned with empirically tailored computing environment, this research discusses the relative performance of six different algorithms of a discrete choice model using three key performance measures： convergence time, number of iterations, and iteration time. The computer codes are developed by using Visual Basic Application （VBA）. Maximum likelihood function （MLF） is formulated and the mathematical relationships of gradient and Hessian matrix are analytically derived to carry out the estimation process. The estimated parameter values clearly suggest that convergence criterion and initial guessing of parameters are the two critical factors in determining the overall estimation performance of a custom-built discrete choice model.
文摘Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed by adopting adaptive step length and improved update strategy of wolf pack. AIBWPA is applied to 10 classic 0-1 knapsack problems and compared with BWPA, DPSO, which proves that AIBWPA has higher optimization accuracy and better computational robustness. AIBWPA makes the parameters simple, protects the population diversity and enhances the global convergence.
文摘The production cycle of open-cast coal mines generally in eludes drilling, blasting, loading, hauling and coal preparation activities. Individual optimization of these activities does not mean that the whole system is optimized. This paper proposes a cost model considering all activities in mining cycle and system-wide approach to minimize the total mining cost of bench production. Since the fragmentation size and blast-hole diameter are linked to all activities of mining system, they are considered as decision variables in the problem form ul at io n. The operatio n costs are then minimized by using the evolutionary algorithm. Moreover, the impact of the change in the explosive price, and the hourly unit cost of equipment on total mining cost is quantified by sensitivity analysis. A case study is implemented to demonstrate the developed model.
基金This project was supported by the National Natural Science Foundation of China (60364001), the Shandong ProvincialNatural Science Foundation of China (Y2004A04) and Fujian Provincial Education Foundation of China(JA04268).
文摘Using S-rough sets, this paper gives the concepts off-heredity knowledge and its heredity coefficient, and f-variation coefficient of knowledge; presents the theorem of f-attribute dependence of variation coefficient and the relation theorem of heredity-variation. The attribute dependence of f-variation coefficient and the relation of heredity-variation are important characteristics of S-rough sets. From such discussion, this paper puts forward the heredity mining off-knowledge and the algorithm of heredity mining, also gives its relative application.
基金This project was supported by the National Natural Science Foundation of China(No.50274047 and 50304001)the Bejing Jiaotong University Foundation.
文摘The pressing bonding of steel plate with QTi3.5-3.5graphite slurry was studied. The relationship among preheating temperature of steel plate, preheating temperature of dies, solid fraction of QTi3.5-3.5graphite slurry, and interfacial shear strength of bonding plate could be established with artificial neural networks perfectly. This model could be optimized with a genetic algorithm. The results show that the optimum bonding parameters are: 618℃ for preheating temperature of steel plate, 526℃ for preheating temperature of dies and 46.2% for solid fraction of QTi3.5-3.5graphite slurry, and the largest interfacial shear strength of bonding plate is 128.3 MPa.
基金Supported by National Natural Science Foundation of China(Grant No.51275307)
文摘As a key to improve the performance of the interbay automated material handling system （AMHS） in 300 mm semiconductor wafer fabrication system, the real- time overhead hoist transport （OHT） dispatching problem has received much attention. This problem is first formu- lated as a special form of assignment problem and it is proved that more than one solution will be obtained by Hungarian algorithm simultaneously. Through proposing and strictly proving two propositions related to the char- acteristics of these solutions, a modified Hungarian algo- rithm is designed to distinguish these solutions. Finally, a new real-time OHT dispatching method is carefully designed by implementing the solution obtained by the modified Hungarian algorithm. The experimental results of discrete event simulations show that, compared with con- ventional Hungarian algorithm dispatching method, the proposed dispatching method that chooses the solution with the maximum variance respectively reduces on average 4 s of the average waiting time and average lead time of wafer lots, and its performance is rather stable in multiple dif- ferent scenarios of the interbay AMHS with different quantities of shortcuts. This research provides an efficient real-time OHT dispatching mechanism for the interbay AMHS with shortcuts and bypasses.
文摘Optimization of antenna array pattern used in a spaceborne Synthetic Aperture Radar (SAR) system is considered in this study. A robust evolutionary algorithm, Non-dominated Sorting Genetic Algorithms (the improved NSGA-Ⅱ), is applied on a spaceborne SAR antenna pattern design. The system consists of two objective functions with two constraints. Pareto fronts are generated as a result of multi-objective optimization. After being validated by a test problem ZDT4, the algorithms are used to synthesize spaceborne SAR antenna radiation pattern. The good results with low Ambi- guity-to-Signal Ratio (ASR) and high directivity are obtained in the paper.
基金The National Natural Science Foundationof China (70473037)
文摘A 0-1 integer programming model for weekly fleet assignment was put forward based on linear network and weekly flight scheduling in China. In this model, the objective function is to maximize the total profit of fleet assignment, subject to the constraints of coverage, aircraft flow balance, fleet size, aircraft availability, aircraft usage, flight restriction, aircraft seat capacity, and stopover. Then the branch-and-bound algorithm based on special ordered set was applied to solve the model. At last, a real- wofld case study on an airline with 5 fleets, 48 aircrafts and 1 786 flight legs indicated that the profit increase was ￥ 1 591276 one week and the running time was no more than 4 rain, which shows that the model and algorithm are fairly good for domestic airline.
基金Supported by the National Natural Science Foundation of China(32072352)。
文摘To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexes(average temperature,average moisture content,average retention rate of the total anthocyanin content,temperature contrast value,and moisture dispersion value)were investigated via the response surface method(RSM)and the artificial neural network(ANN)with genetic algorithm(GA).The results showed that the microwave intensity and drying time dominated the changes of evaluation indexes.Overall,the ANN model was superior to the RSM model with better estimation ability,and higher drying uniformity and anthocyanin retention rate were achieved for the ANN-GA model compared with RSM.The optimal parameters were microwave intensity of 5.53 W•g^(-1),air velocity of 1.22 m·s^(-1),and drying time of 5.85 min.This study might provide guidance for process optimization of microwave drying berry fruits.
