Objective:The study objective was to translate,validate,and test the reliability of the original kidney disease and quality of life-36(KDQOL-36^(TM))instruments in Odia.Materials and Methods:A cross-sectional design w...Objective:The study objective was to translate,validate,and test the reliability of the original kidney disease and quality of life-36(KDQOL-36^(TM))instruments in Odia.Materials and Methods:A cross-sectional design with a purposive sampling technique was used.According to RAND Corporation guidelines,initially,the items of the KDQOL-36^(TM)questionnaires were translated into Odia by two independent,bilingual,professional translators,and then back-translated to English,followed by tryout and field testing.The experts validated the KDQOL-36^(TM)instrument review committee for review related to kidney health conditions.The tool was implemented among 180 patients undergoing“maintenance”hemodialysis.The following tests evaluated reliability and validity:test-retest reliability with Cronbach’s alpha correlation(stability),(reliability)internal consistency,and contents validity index.Results:The Cronbach’s alpha value and intraclass correlation coefficient(ICC)score of all five domains,namely“physical component summary,mental component summary(MCS),the burden of kidney disease,symptoms and problems of kidney disease,and effects of kidney disease”of both KDQOL-36^(TM)English and Odia(KDQOL-36-E^(TM)and KDQOL-36-O^(TM))version,recommended excellent homogeneity.A high positive correlation(r=0.998)was found between the Odia version of KDQOL-36^(TM)and the English version KDQOL-36^(TM)questionnaire.The ICC score ranges from 0.889 to 0.997 at a 95%confidence interval for test-retest reliability,and Cronbach’s alpha was 0.832.Conclusion:This study explores the Odia version of KDQOL-36^(TM)psychometric properties,depicted at an acceptable level of internal consistency.The KDQOL-36-O^(TM)instrument is a valid and reliable tool for assessing the kidney disease-related quality of life in Odia-speaking hemodialysis patients.展开更多
Background: Post hepatitis C virus chronic liver disease (CLD) is prevalent among the Egyptian population with a bad impact upon their quality of life (QOL). Hepatocellular carcinoma (HCC) is one of the long term and ...Background: Post hepatitis C virus chronic liver disease (CLD) is prevalent among the Egyptian population with a bad impact upon their quality of life (QOL). Hepatocellular carcinoma (HCC) is one of the long term and fatal complications of CLD and it also has its negative impact on patient’s quality of life. Aim: To assess impact of CLD and HCC on the quality of life of group of hospitalized elderly patients. Methodology: Ninety elderly patients were divided into three groups: 30 elderly with post hepatitis C virus CLD, 30 elderly with HCC and 30 others free of liver disease as control group (Cn), all were recruited from the in-patient ward and the outpatient clinic of the Geriatric Department, Ain-Shams University Hospital. After giving consent, comprehensive geriatric assessment was done with assessment of their quality of life by using the Short Form-36 health survey (SF-36). Investigations including liver enzymes, serum albumin, serum bilirubin and abdominal ultrasound were done. Results: All QOL domains were the highest among control group, followed by HCC group and the least among CLD group. The differences were statistically significant in most subscales and total score [Mean of Cn = 81.9 ± 12.4, Mean of CLD = 47.5 ± 21.9, Mean of HCC = 62.3 ± 16.1;P Cn/CLD ≤ 0.001, P Cn/HCC ≤ 0.001, P CLD/HCC = 0.004]. Albumin was the only biochemical marker correlated positively with total SF score and two subscales (PF and EF) [r = 0.408;P = 0.025]. Conclusion & Recommendation: Our study showed a decrease in the QOL of Egyptian post hepatitis C virus CLD and HCC patients compared with Egyptian population norms. The results showed that CLD were more affected than HCC patients. This had a particularly serious negative impact on their life. The findings indicate a need for updated counseling and educational materials designed to provide adequate information and consistent healthcare service to this patient setting.展开更多
目的:探讨甲状旁腺全切术(total parathyroidectomy,TPTX)对维持性血液透析(maintenance hemodialysis,MHD)患者临床指标及生活质量的影响。方法:回顾性分析89例继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者手术...目的:探讨甲状旁腺全切术(total parathyroidectomy,TPTX)对维持性血液透析(maintenance hemodialysis,MHD)患者临床指标及生活质量的影响。方法:回顾性分析89例继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者手术前后血清钙、磷、全段甲状旁腺激素(intact parathyroid hormone,IPTH)、碱性磷酸酶、血红蛋白、白蛋白等生化指标变化,应用肾脏病与生活质量问卷36(kidney disease quality of life 36,KDQOL-36)量表和36项简明健康调查问卷(the medical outcome 36-item short form health survey,SF-36)量表对患者进行手术前、后生活质量评估,比较手术前、后生活质量评分变化。结果:术后患者乏力、骨痛、皮肤瘙痒等症状明显改善。术后血清钙、磷、碱性磷酸酶、IPTH较术前明显下降(均P<0.01),血红蛋白、白蛋白较术前明显增加(P<0.01)。术前生活质量评分均较低,TPTX后生活质量评分均显著增加(P<0.01)。术前肾病相关生活质量、一般健康相关生活质量、综合生活质量与血红蛋白、白蛋白呈正相关,与年龄呈负相关(均P<0.05);肾病相关生活质量、综合生活质量与文化程度呈正相关(均P<0.05);一般健康相关生活质量与血清尿素氮、磷呈负相关(均P<0.05)。结论:TPTX可以显著改善难治性SHPT患者的临床指标,提高生活质量。展开更多
目的调查肝硬化患者肝移植前后生存质量的变化情况。方法研究对象为在中山大学附属第三医院移植中心行首次肝移植手术的68例肝硬化患者。分别在术前,术后0～6个月、7～12个月、12个月以上对患者进行问卷调查。问卷采用健康调查简表(medi...目的调查肝硬化患者肝移植前后生存质量的变化情况。方法研究对象为在中山大学附属第三医院移植中心行首次肝移植手术的68例肝硬化患者。分别在术前,术后0～6个月、7～12个月、12个月以上对患者进行问卷调查。问卷采用健康调查简表(medical outcome study 36-item short form health survey,SF-36)与疾病专用调查表——慢性肝病问卷(chronic liver disease questionaire,CLDQ)。结果在肝移植术前,肝硬化患者的SF-36和CLDQ各维度评分均偏低。术后各时段SF-36的生理机能、躯体疼痛、一般健康、精力和CLDQ的腹部症状、乏力、全身症状、活动评分均较术前明显升高(均为P<0.05);与术前比较,术后0～6个月SF-36的生理职能、社会功能、情感职能、精神健康和CLDQ的情感功能、焦虑评分差异无统计学意义(均为P>0.05),但术后7～12个月、术后12个月以上述维度评分比较差异均有统计学意义(均为P<0.05);术后随着时间的推移,两表各维度得分逐步升高。结论肝硬化肝移植患者术后的生存质量与术前比较有明显改善,术后早期以生理功能方面改善明显,随时间的推移,生存质量其他指标如心理状态和社会功能也得到明显的改善。展开更多
目的了解马鞍山市现存尘肺病患者的生命质量,探讨相关影响因素,为寻求提高其生命质量、减轻疾病负担的方法和途径提供依据。方法2022年6—11月,选取现住址为马鞍山市辖区,被确诊为尘肺病的494名患者为调查对象,采用自制量表结合《简明...目的了解马鞍山市现存尘肺病患者的生命质量,探讨相关影响因素,为寻求提高其生命质量、减轻疾病负担的方法和途径提供依据。方法2022年6—11月,选取现住址为马鞍山市辖区,被确诊为尘肺病的494名患者为调查对象,采用自制量表结合《简明健康调查量表》(36-Item Short-Form Health Survey,SF-36)对患者的基本情况、疾病情况及生命质量进行调查,应用多元线性回归模型分析尘肺病患者生命质量的影响因素。结果患者中有男性488例(占98.8%),女性6例(占1.2%);文化程度为小学及以下的有308例(占62.35%),接尘工龄10年以下的有225例(占45.55%);尘肺病分期以壹期为主,共380例(占76.92%);112例(占22.67%)患者有并发症;398例(占80.57%)患者自觉健康状况比1年前差。尘肺病患者总体生命质量得分及躯体功能(PF)、躯体角色(RP)、躯体疼痛(BP)、一般健康状况(GH)、生命力(VT)、社会职能(SF)、情感职能(RE)、心理健康(MH)共8个维度得分均有不同程度下降。多因素分析结果显示,与80岁及以上年龄组患者相比,70~79、60~69、≤59岁组患者生命质量总分分别提高8.171分、13.139分、15.563分(均P<0.001);相对于文化程度小学及以下、有慢性病、有并发症、独居或居住在养老院、接尘工龄≥30年、伤残等级1~4级、尘肺病叁期的患者,文化程度高中及以上、无慢性病、无并发症、与家人居住在一起、接尘工龄≤9年、伤残等级7级及以上、尘肺病壹期的患者的生命质量总分分别提高5.358分、6.897分、6.117分、10.349分、12.386分、6.347分和15.152分(均P<0.05)。结论马鞍山市尘肺病患者总体生命质量不高,建议重点关注年龄较大、独居或居住在养老院、患有慢性病或尘肺病并发症、低学历,以及尘肺病分期较高的尘肺病患者的生命质量状况。展开更多
文摘Objective:The study objective was to translate,validate,and test the reliability of the original kidney disease and quality of life-36(KDQOL-36^(TM))instruments in Odia.Materials and Methods:A cross-sectional design with a purposive sampling technique was used.According to RAND Corporation guidelines,initially,the items of the KDQOL-36^(TM)questionnaires were translated into Odia by two independent,bilingual,professional translators,and then back-translated to English,followed by tryout and field testing.The experts validated the KDQOL-36^(TM)instrument review committee for review related to kidney health conditions.The tool was implemented among 180 patients undergoing“maintenance”hemodialysis.The following tests evaluated reliability and validity:test-retest reliability with Cronbach’s alpha correlation(stability),(reliability)internal consistency,and contents validity index.Results:The Cronbach’s alpha value and intraclass correlation coefficient(ICC)score of all five domains,namely“physical component summary,mental component summary(MCS),the burden of kidney disease,symptoms and problems of kidney disease,and effects of kidney disease”of both KDQOL-36^(TM)English and Odia(KDQOL-36-E^(TM)and KDQOL-36-O^(TM))version,recommended excellent homogeneity.A high positive correlation(r=0.998)was found between the Odia version of KDQOL-36^(TM)and the English version KDQOL-36^(TM)questionnaire.The ICC score ranges from 0.889 to 0.997 at a 95%confidence interval for test-retest reliability,and Cronbach’s alpha was 0.832.Conclusion:This study explores the Odia version of KDQOL-36^(TM)psychometric properties,depicted at an acceptable level of internal consistency.The KDQOL-36-O^(TM)instrument is a valid and reliable tool for assessing the kidney disease-related quality of life in Odia-speaking hemodialysis patients.
文摘Background: Post hepatitis C virus chronic liver disease (CLD) is prevalent among the Egyptian population with a bad impact upon their quality of life (QOL). Hepatocellular carcinoma (HCC) is one of the long term and fatal complications of CLD and it also has its negative impact on patient’s quality of life. Aim: To assess impact of CLD and HCC on the quality of life of group of hospitalized elderly patients. Methodology: Ninety elderly patients were divided into three groups: 30 elderly with post hepatitis C virus CLD, 30 elderly with HCC and 30 others free of liver disease as control group (Cn), all were recruited from the in-patient ward and the outpatient clinic of the Geriatric Department, Ain-Shams University Hospital. After giving consent, comprehensive geriatric assessment was done with assessment of their quality of life by using the Short Form-36 health survey (SF-36). Investigations including liver enzymes, serum albumin, serum bilirubin and abdominal ultrasound were done. Results: All QOL domains were the highest among control group, followed by HCC group and the least among CLD group. The differences were statistically significant in most subscales and total score [Mean of Cn = 81.9 ± 12.4, Mean of CLD = 47.5 ± 21.9, Mean of HCC = 62.3 ± 16.1;P Cn/CLD ≤ 0.001, P Cn/HCC ≤ 0.001, P CLD/HCC = 0.004]. Albumin was the only biochemical marker correlated positively with total SF score and two subscales (PF and EF) [r = 0.408;P = 0.025]. Conclusion & Recommendation: Our study showed a decrease in the QOL of Egyptian post hepatitis C virus CLD and HCC patients compared with Egyptian population norms. The results showed that CLD were more affected than HCC patients. This had a particularly serious negative impact on their life. The findings indicate a need for updated counseling and educational materials designed to provide adequate information and consistent healthcare service to this patient setting.
文摘目的:探讨甲状旁腺全切术(total parathyroidectomy,TPTX)对维持性血液透析(maintenance hemodialysis,MHD)患者临床指标及生活质量的影响。方法:回顾性分析89例继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者手术前后血清钙、磷、全段甲状旁腺激素(intact parathyroid hormone,IPTH)、碱性磷酸酶、血红蛋白、白蛋白等生化指标变化,应用肾脏病与生活质量问卷36(kidney disease quality of life 36,KDQOL-36)量表和36项简明健康调查问卷(the medical outcome 36-item short form health survey,SF-36)量表对患者进行手术前、后生活质量评估,比较手术前、后生活质量评分变化。结果:术后患者乏力、骨痛、皮肤瘙痒等症状明显改善。术后血清钙、磷、碱性磷酸酶、IPTH较术前明显下降(均P<0.01),血红蛋白、白蛋白较术前明显增加(P<0.01)。术前生活质量评分均较低,TPTX后生活质量评分均显著增加(P<0.01)。术前肾病相关生活质量、一般健康相关生活质量、综合生活质量与血红蛋白、白蛋白呈正相关,与年龄呈负相关(均P<0.05);肾病相关生活质量、综合生活质量与文化程度呈正相关(均P<0.05);一般健康相关生活质量与血清尿素氮、磷呈负相关(均P<0.05)。结论:TPTX可以显著改善难治性SHPT患者的临床指标,提高生活质量。
文摘目的调查肝硬化患者肝移植前后生存质量的变化情况。方法研究对象为在中山大学附属第三医院移植中心行首次肝移植手术的68例肝硬化患者。分别在术前,术后0～6个月、7～12个月、12个月以上对患者进行问卷调查。问卷采用健康调查简表(medical outcome study 36-item short form health survey,SF-36)与疾病专用调查表——慢性肝病问卷(chronic liver disease questionaire,CLDQ)。结果在肝移植术前,肝硬化患者的SF-36和CLDQ各维度评分均偏低。术后各时段SF-36的生理机能、躯体疼痛、一般健康、精力和CLDQ的腹部症状、乏力、全身症状、活动评分均较术前明显升高(均为P<0.05);与术前比较,术后0～6个月SF-36的生理职能、社会功能、情感职能、精神健康和CLDQ的情感功能、焦虑评分差异无统计学意义(均为P>0.05),但术后7～12个月、术后12个月以上述维度评分比较差异均有统计学意义(均为P<0.05);术后随着时间的推移,两表各维度得分逐步升高。结论肝硬化肝移植患者术后的生存质量与术前比较有明显改善,术后早期以生理功能方面改善明显,随时间的推移,生存质量其他指标如心理状态和社会功能也得到明显的改善。
文摘目的了解马鞍山市现存尘肺病患者的生命质量,探讨相关影响因素,为寻求提高其生命质量、减轻疾病负担的方法和途径提供依据。方法2022年6—11月,选取现住址为马鞍山市辖区,被确诊为尘肺病的494名患者为调查对象,采用自制量表结合《简明健康调查量表》(36-Item Short-Form Health Survey,SF-36)对患者的基本情况、疾病情况及生命质量进行调查,应用多元线性回归模型分析尘肺病患者生命质量的影响因素。结果患者中有男性488例(占98.8%),女性6例(占1.2%);文化程度为小学及以下的有308例(占62.35%),接尘工龄10年以下的有225例(占45.55%);尘肺病分期以壹期为主,共380例(占76.92%);112例(占22.67%)患者有并发症;398例(占80.57%)患者自觉健康状况比1年前差。尘肺病患者总体生命质量得分及躯体功能(PF)、躯体角色(RP)、躯体疼痛(BP)、一般健康状况(GH)、生命力(VT)、社会职能(SF)、情感职能(RE)、心理健康(MH)共8个维度得分均有不同程度下降。多因素分析结果显示,与80岁及以上年龄组患者相比,70~79、60~69、≤59岁组患者生命质量总分分别提高8.171分、13.139分、15.563分(均P<0.001);相对于文化程度小学及以下、有慢性病、有并发症、独居或居住在养老院、接尘工龄≥30年、伤残等级1~4级、尘肺病叁期的患者,文化程度高中及以上、无慢性病、无并发症、与家人居住在一起、接尘工龄≤9年、伤残等级7级及以上、尘肺病壹期的患者的生命质量总分分别提高5.358分、6.897分、6.117分、10.349分、12.386分、6.347分和15.152分(均P<0.05)。结论马鞍山市尘肺病患者总体生命质量不高,建议重点关注年龄较大、独居或居住在养老院、患有慢性病或尘肺病并发症、低学历,以及尘肺病分期较高的尘肺病患者的生命质量状况。
